Digital Commons Network^™

Enhancing Webtas: From An Atam Simulator To A Developmental Environment, Elizabeth G. Schmidt

Electrical Engineering and Computer Science Undergraduate Honors Theses

As interest in a niche research area, like the abstract Tile Assembly Model (aTAM), grows it is crucial to ensure that simulation tools are accessible and user-friendly for a broad audience. Existing resources can pose challenges for less experienced users, highlighting the need for enhancements that improve usability and functionality. To address these issues, key upgrades to the current online simulation platform, WebTAS, were implemented, including breakpoint functionality and nondeterminism checks, alongside features such as XML file integration, image capturing, and simulation view resets. These enhancements collectively elevate the platform from a basic learning tool to a comprehensive environment for …

Assessing Reproducibility Challenges In Clinical Metabolics, Darcy Lin Cochran

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Current metabolomics research is expanding to be multiplatform and interdisciplinary. Metabolomic analysis has the potential to provide detailed insight into any biological system of interest to analyze the underlying molecular mechanisms of variables like environment, disease, and genetics. Human clinical metabolomics is a major research area that is often focused on finding biomarkers or panels of biomarkers for different diseases. However, results are difficult to compare across different laboratories since the field of metabolomics has yet to widely adopt best practices for sample preparation, data acquisition and data processing, results are difficult to compare across different laboratories.

This thesis focuses …

Uncovering The Light Network Load Performance Penalty Of The Network Link Outlier Factor (Nlof), Michelle Lara

Open Access Theses & Dissertations

This thesis evaluates the effectiveness of the Network Link Outlier Factor with Most Likely Link (NLOF: MLL) algorithm under varying network load conditions. Repeated simulation experiments using Mininet were conducted for four different network-wide load levels: 100 Mbps, 500 Mbps, 1 Gbps, and 5 Gbps. Using statistical inference, our experimental results indicate that NLOF: MLL is ineffective under light load conditions (i.e., 100Mbps load) due to the limited network flow data available for its learning process. This limitation highlights a key challenge in applying the algorithm to lightly loaded networks. A preliminary algorithm was proposed to address this light-load performance …

Ultra-High Temperature Ceramics: Materials, Manufacturing, And Machine Development, Joseph Matthew Munoz

Open Access Theses & Dissertations

This research aimed to advance the 3D printing of ultra-high-temperature ceramic matrix composites (UHTCMCs) and develop a custom Direct Ink Writing (DIW) system with multimaterial and in-line mixing capabilities. The study first focused on creating ZrB₂–SiC composites reinforced with aligned silicon carbide fibers (SiCf) using paste extrusion. By formulating suspensions with a preceramic polymer (SMP-10), ZrB₂, and SiCf, the study assessed how fiber alignment influenced key properties such as thermal and electrical conductivity and mechanical strength. Green curing and pyrolysis transformed the printed parts into UHTCMCs, with results showing substantial improvements in thermal conductivity—nearly double that of non-aligned parts—and a …

Advancements In Polymer Synthesis And Ceramic Additive Manufacturing For Energy Applications, Sofia Gabriela Gomez

Open Access Theses & Dissertations

The aim of this work was to create polymer and ceramic materials for integration into energy applications. The first part of this research was to fabricate polymer syntactic foams that exhibited high energy absorption capabilities. The fabrication of polymer syntactic foams was feasible through synthesizing hollow polysiloxane microspheres that were imbedded into a polydimethylsiloxane (PDMS) matrix. An array of characterization techniques was used to test the material and physical properties of the syntactic foams. The next step of this research was to fabricate a porous water emulsion foam ink for use in Direct-Ink-Write (DIW) additive manufacturing (AM) technologies. Unlike the …

General Purpose Gpu Benchmarks For Neural Networks, Jose Maria Granados

Open Access Theses & Dissertations

Neural networks are a field of computing experiencing a rise in popularity in recent years due to the utilization of graphics processing units as their computational centerpiece. The lack of neural network benchmarks for the open-source Nyuzi architecture, a developing general-purpose processor with graphical processing capabilities, is the focus of this thesis. This work aims to determine whether Nyuziâ??s performance counters and traceable events suffice for performance tuning of neural network implementations. Given the mathematical intensity of neural networks, a strong emphasis is placed on events related to arithmetic instructions. Experimenting with neural network implementations in C and C++, existent …

Sensitive Grip Mounting Surfaces For Physical Human-Robot Interaction., Branden Shay

Electronic Theses and Dissertations

As the development of robotics becomes ever increasingly present in our society, the need for studying how humans and robots interact with each other becomes more of a necessity to be properly integrated in the changing world around us. In this thesis, we undertake the study and development of how to create a tactile human-robot operator interface to guide a robot perform a physical task. The implementation of tactile interfaces such as SkinCell sensor arrays emulating skin, and of a robotic handlebar fitted with tactile sensors are critical examples of the challenges that come with mounting and packaging such sensors …

Study Of Temperature Effects Of Glucose And Microwave Dielectric Dispersion Model, Ethan Grant Boone

Theses and Dissertations

In this study, the temperature effect of dielectric properties in various aqueous solutions containing glucose are examined. A design for a new testing chamber is introduced to provide improved conditions for testing to ensure accurate and precise measurements. A N-SMA Adaptor is used when obtaining dielectric characteristics of glucose solutions ranging 100-300mg/dl. Dielectric parameters are obtained adopting a modified Debye dispersion model. MATLAB is used to confirm coaxial dimensions are suitable fabrication designs using fixed dielectric parameters of air and water. Simulations and design models were implemented utilizing ANSYS High Frequency Structure Simulator and 3-D Modeler software to develop the …

3d Bioprinted Coaxial Tubule Optimization For Human Aortic Endothelial Cell Growth, Ilse Gabriela Perez Garcia

Theses and Dissertations

This paper introduces a research study of printing parameter optimization of extruded, cell-laden, 3D bioprinted coaxial tubules, as well as cell interaction observations. Optimization of printing parameters seeks to reduce variability of the tubules’ inner and outer diameters. The tubules were manufactured from a 0.4% Collagen I - 1.6% NaC6H7O6 (Sodium Alginate) bioink, that reaches gelation through interaction with a 3.2% CaCl2 (Calcium Chloride) solution. The bioinks were extruded through a dual syringe pump mechanism connected to a coaxial nozzle, which is mounted on an adapted 3D FDM (Fused Deposition …

Resonances Of Electrostatically Actuated Non-Uniform Mems Cantilever Resonator Of Constant Width And Linearly Varying Thickness, Rigoberto Flores

Theses and Dissertations

In this investigation the behavior of an electrostatically actuated non-uniform microelectromechanical (MEMS) cantilever resonator of constant width and linearly varying thickness is investigated. The cantilever resonator vibrates using soft AC voltage at near half the first natural frequency of the cantilever and near the first natural frequency of the cantilever, known as primary and parametric resonances, respectively. Bifurcation diagrams for the amplitude-frequency and amplitude-voltage response are obtained for both resonances. Two methods are used in this investigation, namely the Method of Multiple Scales (MMS) and Reduced Order Model (ROM) using up to 6 modes of vibration.

These methods are used …

Physicochemical Property Effects On Immune Modulating Polymeric Nanoparticles: Potential Applications In Spinal Cord Injury, Daniel J. Kolpek, Jaechang Kim, Hisham Mohammed, John C. Gensel, Jonghyuck Park

Markey Cancer Center Faculty Publications

Nanoparticles (NPs) offer promising potential as therapeutic agents for inflammation-related diseases, owing to their capabilities in drug delivery and immune modulation. In preclinical studies focusing on spinal cord injury (SCI), polymeric NPs have demonstrated the ability to reprogram innate immune cells. This reprogramming results in redirecting immune cells away from the injury site, downregulating pro-inflammatory signaling, and promoting a regenerative environment post-injury. However, to fully understand the mechanisms driving these effects and maximize therapeutic efficacy, it is crucial to assess NP interactions with innate immune cells. This review examines how the physicochemical properties of polymeric NPs influence their modulation of …

Engineering Faculty Perceptions On Student-Use Of Generative Artificial Intelligence (Gai) In Course Completion, Michaela Harper

All Graduate Theses and Dissertations, Fall 2023 to Present

Computer science and engineering faculty often argue whether students should be allowed to use GAI tools, such as ChatGPT, or banned from using them for fear of decreasing learning and workforce quality. This research gathers and reports engineering and computer science faculty members’ perceptions, opinions, and recommendations for GAI use in higher education. Faculty members agree that these technologies are here to stay and must be understood to address GAI in college and university courses. However, their willingness to implement GAI into their courses varied based on prior experience in industry and with the technology itself. Those with very limited …

Assessing Khumbu Region Glaciers Mass Balance Change Using Geospatial Techniques From 2012 To 2024, Yashvi Jagatbhai Shah

Electronic Theses, Projects, and Dissertations

The glaciers in the Hindu Kush Himalaya are critical for sustaining the water supply of South Asia's major rivers, upon which over 230 million people, both in the mountainous regions and lowland areas, depend. Climate change is driving rapid glaciers melt near the summit of Mount Everest, located at an elevation of approximately 7,906 meters (25,938 feet). This has resulted in glacier thinning occurring up to 80 times faster than the original ice formation. However, due to their disposition in a complex topographic setting and inaccessible terrain, continuous glacier observations pose significant challenges.

This study evaluated the mass balance of …

Life Cycle Assessment Approach For Energy Usage In Animal Rendering Plants, Abel Binoy Mathew

All Theses

The animal rendering industry plays a crucial role in transforming waste products from livestock production and meat processing facilities into valuable and economically beneficial products, promoting both resource efficiency and sustainability. This study uses a life cycle assessment (LCA) approach to evaluate energy usage and greenhouse gas emissions in animal rendering plants, focusing on electricity and natural gas as the main energy inputs for plant operation. This research examines three distinct rendering facilities, each processing different raw materials, to quantify the environmental impacts of rendering operations. Site visits, data collection, and real-time monitoring were used to capture energy use across …

Microbial-Chemical Degradation Of Styrene In Co-Mingled Plumes With Ethylbenzene, Benzene, And Carbon Tetrachloride, Marcela C. Flórez-García

All Theses

Industrial sites contaminated with a complex matrix of chemicals represent a problem for the ecosystem and a high risk for the health of all individuals. That is why remediation strategies are needed to mitigate this environmental impact. The latex zone, located at the Corteva industrial site in San Lorenzo, Argentina, is the subject of this research. The environmental impacts in this area are a consequence of petrochemical operations carried out for many years.

Monoaromatic hydrocarbons such as styrene, ethylbenzene, and benzene, and chlorinated methanes like carbon tetrachloride, chloroform, dichloromethane, and chloromethane are among the contaminants identified at the site that …

Growing Industry-University Partnerships: Virtual Workshop On Industry Sponsored Research, Mark Stone, Santosh K. Pitla

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

The Department of Biological Systems Engineering (BSE) at the University of Nebraska-Lincoln (UNL) hosted a virtual workshop on developing capacity for industry-sponsored research (ISR). This dynamic event brought together faculty, researchers, industry leaders, and students to explore innovative strategies for advancing ISR.

The workshop addressed four key themes: (1) fostering sustainable industry-academic partnerships; (2) tackling intellectual property (IP) challenges; (3) building institutional and individual capacity for ISR, and (4) empowering students as critical contributors to industry research. Through expert-led presentations, an engaging panel discussion, and interactive brainstorming sessions, participants identified actionable steps and articulated a vision for the future of …

On Neutrosophic Pδs-Irresolute Functions In Neutrosophic Topological Spaces, Bishnupada Debnath, Anjan Mukherjee

Neutrosophic Systems with Applications

In general topology the notion of pds-irresolute and aδs-irresolute functions were introduced by Beceren and Noiri. In the present paper, these concepts of pδs-irresolute (briefly, Npδs-irresolute) and aδs-irresolute (briefly, Naδs-irresolute) functions are explored for the first time in neutrosophic topological spaces (NTS) as generalized version. We proved that every Naδs-irresolute function is Npδs-irresolute function but not conversely. Some characterizations, counter examples, and fundamental features are also presented. By neutrosophic pre-open, neutrosophic δ-open, and neutrosophic δ-semi-open sets, some new fundamental properties of such functions are provided. Furthermore, under Npδs-irresolute functions, the behavior of neutrosophic semi-connected, neutrosophic pre-connected, neutrosophic pre-T2, neutrosophic δ-semi-T2, …

Zero-G Exercise Equipment, Charisse Biglete, Jake Brajevich, James Monroe, Ethan Siahpush

Mechanical Engineering

In a micro-gravitational environment, the body undergoes less loading than that found on Earth. This leads to muscular atrophy, Osteoporosis, decreases in protein synthesis, and various other undesirable outcomes. To prevent this, astronauts undergo a strict exercise regime to maintain their health. The current exercise equipment available for spacecraft is large, heavy, complicated to use, costly, and unsafe. There is a definite need for the re-engineering of the exercise equipment to be used by astronauts while in microgravity environments to rectify these issues.

Fabrication And Charcaterization Of Pullulan-Collagen Nanofibers Via Forcespinning, Valeria Leon Leal

Theses and Dissertations

Extensive research on collagen has spurred advancements in tissue engineering and biomaterial development, given collagen´s pivotal role in regulating various tissue structures across diverse organisms. This study delves into fabricating nanocomposites utilizing collagen, along with silver nanoparticles, chondroitin sulfate and pullulan, for potential applications in antibacterial medical devices, and cell regeneration. Collagen, abundant in the extracellular matrix, provides essential structural support, while silver nanoparticles and chondroitin confer antimicrobial properties, crucial for combating infections. Pullulan, a polysaccharide polymer, serves as a biocompatible carrier for silver nanoparticles whilst being the starting nanofiber forming material. Utilizing Forcespinning® technology, composite nanofibers were successfully synthesized. …

Three-Dimensional Environmentally Sustainable Neuromorphic Computing System Based On Natural Organic Memristor, Mohammed Rafeeq Khan

Graduate Theses and Dissertations (2019 - present)

A three-dimensional neuromorphic (3D) computing architecture based on environmentally sustainable natural organic honey memristors is proposed in this thesis. A set of comprehensive and experimental results indicate that the proposed systems exhibit remarkable inference accuracy, consistently surpassing the 90% threshold, even with different challenges such as device variations and nonlinearity. This study also considers four different conductance drift situations, the effects of analog-to-digital converter (ADC) quantization, and multiple algorithms, such as VGG8 and DenseNet-40. The deliverable of this thesis will test the stability of the proposed systems and explore their potential applications and scalability in real-world situations.

The Clot Thickens: Investigation Of The Mechanism Behind Hypercoagulation In Covid-19 Patients, Toni Warnick

All Dissertations

Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with cardiovascular complications, which correlate with illness severity and increased mortality. It was initially thought that this hypercoagulable state was induced by endothelial dysfunction or cytokine storm because of SARS-CoV-2 infection. Although platelets have been reported to express the SARS-CoV-2 primary target receptor, angiotensin-converting enzyme 2 (ACE2), this remains controversial due to conflicting findings that suggest minimal to no ACE2 expression on platelets. This ambiguity has led to exploring alternative entry pathways, notably via the virus’s RGD (arginine-glycine-aspartic acid) sequence within its spike protein receptor-binding …

Magnetic Nano And Micro Rods As Tools For Characterizing Materials Mechanical Properties: Fundamentals And Applications, Artis Brasovs

All Dissertations

The focus of this dissertation is insect blood (Hemolymph). Hemolymph is analyzed by taking a materials science approach. Rheological characterization of hemolymph has been performed for the first time. Owing to a minute amount of available material, a new protocol was established where Magnetic Rotational Spectroscopy (MRS) with ferromagnetic nanorods was employed. The challenge was examining the microliter droplets' viscosity in less than a few minutes. This challenge was successfully resolved.

Blood is critical for the insect's survival: after wounding, the insect has to seal the wound quickly, in a few minutes. As the mechanism of fast clotting has never …

Optimization Of Polymeric Micelles As A Delivery System For Crispr/Cas9 Ribonucleoprotein, Lucian Williams

All Dissertations

Clustered regularly interspaced short palindromic repeats (CRISPR) is an adaptive immune system in bacteria that has been harnessed to perform precise genetic modifications in mammalian cells. Among CRISPR-associated (Cas) proteins, Cas9 has emerged as a transformative tool in gene editing due to its simplicity, high specificity, and versatility compared to the other Cas proteins and gene-editing technologies. Despite its potential to cure genetic disorders, the clinical application of Cas9 has been hindered by challenges such as immunogenicity, off-target effects, and low delivery efficiency. To address these issues, this dissertation explores using polymeric nanoparticle systems to encapsulate and protect Cas9 and …

Supporting Holistic, Informed, Decision-Making Through The Complementarity Of Life Cycle Assessment And Radiological Protection, Bryanna Wattier-Weisensee

All Dissertations

Decision making is challenging and it is necessary to consider all relevant data to make an informed decision. The work herein provides a pathway wherein the fields of radiological protection and life cycle assessment (LCA) can be utilized synergistically to benefit the decision-making using the other (and vice versa). Specifically, LCA parallels decision-aiding techniques used in the optimization of radiological protection and LCA includes an ionizing radiation potential (IRP) impact category wherein the impacts associated with an emission of radioactive material is quantified to determine the human health impact. Thus this body of work focuses on (1) expanding the platform …

Investigating The Role Of Cd44 In Her2+ Breast Cancer Cells During Cancer Cell Redirection, Holly Caroline Jordan Campbell

All Dissertations

Despite a rise in survival rates of breast cancer patients due to advances in modern medicine, breast cancer is the most common type of cancer in women and is the second leading cause of cancer death in the United States. Early detection and a more personalized treatment of breast cancer has slowly improved patient outcomes. Nevertheless, there are impediments to better patient outcomes due to the complexity of the disease physiology. Therefore, there is a demand for a comprehensive understanding of cancer development as well as a need to understand tumor progression for enhanced therapies for patients.

Previous in vivo …

Evaluation Of 3d Beach Profiles: A New Method For Monitoring Changes In Beach Morphology And Grain Size, Kalinda Ellen Roberts

Graduate Masters Theses

Beach profiles are a simple and affordable approach to monitoring changes in beach morphology. However, traditional methods offer limited resolution and dimension. Recent advancements in technologies, particularly structure-from-motion (SfM) and grain size detection models (GSDMs), can be integrated into conventional beach profiling techniques, enabling more detailed spatial and temporal analysis of slope and grain sizes. This research introduces a new technique for coastal monitoring, termed “3D Beach Profiles,” which integrates SfM technology to create high-resolution three-dimensional digital surface models (DSMs) and orthomosaics of beach surfaces. These digital surfaces enable the extraction of beach slopes with orders of magnitude more data …

Neutrosophic Cox Proportional Hazards Model For Robust Variable Selection In Survival Analysis, Ibrahim Yasser, Aya A. Abd El-Khalek, A. A. Salama, Doaa A. Abdo

Neutrosophic Systems with Applications

This paper introduces a novel approach for variable selection in survival analysis by integrating neutrosophic logic into the Cox Proportional Hazards (Cox PH) model to address the limitations of recent studies related to high dimensionality. Neutrosophic logic, is a mathematical framework that allows for uncertainty, indeterminacy, and inconsistency, and particularly well suited for handling the complexity and often-ambiguous nature of biological data. By incorporating neutrosophic sets into the Cox PH model, we aim to enhance model robustness, improve variable selection, and address the curse of dimensionality. We compare the performance of the neutrosophic-enhanced Cox PH model with traditional variable selection …

Exploring Variably Saturated Flow Formulations For Modflow: Implementing A Fully 3d Richards' Equation In Modflow 6, Sebastian Vazquez-Gasty

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

This thesis explores the implementation of a fully 3D Richards’ equation solution into MODFLOW 6 to solve for saturated/unsaturated flow. Currently, MODFLOW 6 has limited capability for solving unsaturated zone flow problems by using the Unsaturated Zone Flow (UZF) package, which neglects capillarity and assumes vertical 1-dimensional flow. Various formulations of the Richards’ equation were first evaluated for their strengths and weaknesses. Various numerical solution approaches to Richards’ equation were also studied to understand the robustness and efficiency of different approaches and to select one that would best fit into the MODFLOW 6 framework. The MODFLOW 6 framework was also …

Argument Schema Of Undergraduate Engineering Students, Anu Singh

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Critical thinking is one of the most desired skills in the workplace, as it assists an individual in solving complex problems and making informed decisions, resulting in their workplace success. Argumentation is one instructional approach that provides students an opportunity to engage in higher-order thinking and improve their communication skills. Argumentative writing provides opportunities to engage in multiple perspectives of a problem, provide evidence for the claim, evaluate evidence, engage in reasoning, and acknowledge self-bias, which automatically engages students in critical thinking. Previous literature has shown that despite the use of interventions and scaffolding approaches, students' argumentative texts lack elements …

Understanding Failure Mechanisms For Two Colorectal Anastomosis Techniques, Youssef Sherif Sadek Fahmy

UNLV Theses, Dissertations, Professional Papers, and Capstones

Colorectal Surgery continues to be one of the most common gastrointestinal surgeries performed in the US. A common complication known as Anastomotic Leakage (AL) that threatens up to 30% of patients with this surgery. Many cases of AL can decrease the quality of life for patients or extensively extend hospital stays, and in many cases, lead to death. Researchers have studied this complication in clinical trials, yet few studied the mechanics of stapled anastomosis in controlled environments. The purpose of this research was to understand the mechanical interaction between the staples and the tissue, and to eventually apply it in …