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Cfd Simulation Of Pharmaceutical Particle Drying In A Bubbling Fluidized Bed Reactor, Jungkee Jang, Cezar Rosa, Hamid Arastoopour

The 13th International Conference on Fluidization - New Paradigm in Fluidization Engineering

The bubbling fluidized bed flow regime is characterized by high heat and mass transfer rate and leads to a relatively short drying time. In this study, the gas-solid mixing and drying of pharmaceutical particles in a bubbling fluidized bed reactor was simulated using Computational Fluid Dynamics approach.

A Perspective On Development Of Novel Fluidized Bed Processes For A More Sustainable Global Future, John Grace

The 13th International Conference on Fluidization - New Paradigm in Fluidization Engineering

Faced with the need for transformative changes to solve global problems, fluidization could play a major role in contributing in areas like carbon capture, use of renewable resources, and recovery of valuable materials from waste streams. Some current examples are discussed where the fluidization community can help to find solutions

Subject Index, Sang Done Kim

The 13th International Conference on Fluidization - New Paradigm in Fluidization Engineering

Index

Processing Of Pure Vegetable Oils In A Continuous Fcc Pilot Plant, Peter Bielansky, Alexander Reichhold, Christoph Schönberger

The 13th International Conference on Fluidization - New Paradigm in Fluidization Engineering

The basic objective of the presented work is the application of vegetable oils as an alternative CO2-neutral feedstock for fluid catalytic cracking (FCC). The experimental test program was conducted in a fully continuously operated FCC pilot plant with intern CFB-design at Vienna University of Technology. Vegetable oils with the highest global production (soy bean oil, palm oil and rapeseed oil) were used. The addition of vegetable oil had hardly any influence on the cracking process. The gasoline achieved is oxygen free at high octane numbers.

Dem Fluidization Of Smart Particles, Amit Suri, Masayuki Horio

The 13th International Conference on Fluidization - New Paradigm in Fluidization Engineering

Numerical simulations using DEM for smart particles/bodies having a capability to induce a repulsive force on the particle based on the cognition were simulated. A particle-particle interaction type repulsive force was used to induce self fluidization and it was found that if the repulsive force is sufficiently high, fluidization of particles can be achieved.

Design And Analysis Of A Compliant Mechanism Spinal Implant, Eric M. Stratton

Theses and Dissertations

This thesis introduces and presents the modeling of a novel compliant spinal implant designed to reduce back pain and restore function to degenerate spinal disc tissues as well as provide a mechanical environment conducive to healing the tissues. The initial objectives for this device development and the focus of this work are modeling and validation of the force-deflection relationships and stress analysis. Modeling was done using the pseudo-rigid-body model to create a 3 degree of freedom mechanism for flexion-extension (forward-backward bending) and a 5 degree of freedom mechanism for lateral bending (side-to-side). These models were analyzed using the principle of …

An Ensemble-Based Computational Approach For Incremental Learning In Non-Stationary Environments Related To Schema- And Scaffolding-Based Human Learning, Ryan Elwell

Theses and Dissertations

The principal dilemma in a learning process, whether human or computer, is adapting to new information, especially in cases where this new information conflicts with what was previously learned. The design of computer models for incremental learning is an emerging topic for classification and prediction of large-scale data streams undergoing change in underlying class distributions (definitions) over time; yet currently, they often ignore significant foundational learning theory that has been developed in the domain of human learning. This shortfall leads to many deficiencies in the ability to organize existing knowledge and to retain relevant knowledge for long periods of time. …

A Reactive Molecular Dynamics Simulation Of The Silica-Water Interface, Joseph C. Fogarty, Hasan Metin Aktulga, Ananth Y. Grama, Adri C. T. Van Duin, Sagar A. Pandit

PRISM: NNSA Center for Prediction of Reliability, Integrity and Survivability of Microsystems

We report our study of a silica-water interface using reactive molecular dynamics. This first-of-its-kind simulation achieves length and time scales required to investigate the detailed chemistry of the system. Our molecular dynamics approach is based on the ReaxFF force field of van Duin [J. Phys. Chem. A 107, 3803 (2003)]. The specific ReaxFF implementation (SERIALREAX) and force fields are first validated on structural properties of pure silica and water systems. Chemical reactions between reactive water and dangling bonds on a freshly cut silica surface are analyzed by studying changing chemical composition at the interface. In our simulations, reactions involving silanol …

Computation Intelligence Method To Find Generic Non-Coding Rna Search Models, Jennifer A. Smith

Electrical and Computer Engineering Faculty Publications and Presentations

Fairly effective methods exist for finding new noncoding RNA genes using search models based on known families of ncRNA genes (for example covariance models). However, these models only find new members of the existing families and are not useful in finding potential members of novel ncRNA families. Other problems with family-specific search include large processing requirements, ambiguity in defining which sequences form a family and lack of sufficient numbers of known sequences to properly estimate model parameters. An ncRNA search model is proposed which includes a collection of non-overlapping RNA hairpin structure covariance models. The hairpin models are chosen from …

Detection And Filtering Of Landmark Occlusions Using Terrain Spatiograms, Damian M. Lyons

Faculty Publications

A team of robots cooperating to quickly produce a map needs to share landmark information between members so that the local maps can be accurately merged. However, the appearance of landmarks as seen by members of the team can change dramatically due to the phenomenon of occlusion.

We have previously presented an approach to landmark representation using Terrain Spatiograms – an extension to image spatiograms in which the spatial information relates to the scene rather than the image. Because this representation preserves depth structure, it is possible to identify and filter potential occlusions.

We present an approach to identifying and …

Acceleration Of Spiking Neural Networks On Single-Gpu And Multi-Gpu Systems, Venkittaraman Vivek Pallipuram Krishnamani

All Theses

There has been a strong interest in modeling a mammalian brain in order to study the architectural and functional principles of the brain and offer tools to neuroscientists and medical researchers for related studies. Artificial Neural Networks (ANNs) are compute models that try to simulate the structure and/or the functional behavior of neurons and process information using the connectionist approach to computation. Hence, the ANNs are the viable options for such studies.
Of many classes of ANNs, Spiking Neuron Network models (SNNs) have been employed to simulate mammalian brain, capturing its functionality and inference capabilities. In this class of neuron …

Liquid-Liquid Equilibrium For Iodine-Hydroiodic Acid-Water Mixtures At Elevated Temperatures And Pressures For The Sulfur-Iodine Cycle, Sarah Mena

All Theses

An alternative scenario to the overdependence on fossil fuels is the use of thermochemical cycles to split water into hydrogen and oxygen. The Sulfur-Iodine (SI) cycle, developed at General Atomics in the mid 1970s, is a leading candidate of international interest for the centralized production of hydrogen from nuclear and/or solar power. For a comprehensive assessment of the SI cycle, thermodynamic data for I2-HI-H2O mixtures at elevated temperatures and pressures have been identified as a basic research need.

The focus of this study was liquid-liquid equilibrium (LLE) measurements for the above system. To carry out the measurements, a continuous-flow apparatus …

Sensitivity Constrained Pmu Placement Utilizing Multiple Methods, Zheng Zhao

All Theses

Phasor Measurement Unit (PMU), which is based on the GPS technique, is able to provide power engineers with immediate and precise measurements. By utilizing PMUs, the reliability and stability in power system are expected to be improved. Conventionally, an optimal PMU placement is considered to use the least number of units to make the entire system completely observable. In this thesis, it is recommended to not only optimize the number of PMUs but also install the majority of PMUs on the most sensitive buses in a power system. Thus a bus sensitivity analysis based on Decoupled Power Flow method is …

Equilibrium Studies And Kinetics Mechanism For The Removal Of Basic And Reactive Dyes In Both Single And Binary Systems Using Edta Modified Rice Husk, Siew-Teng Ong, Weng-Nam Lee, Pei-Sin Keng, Yung-Tse Hung, Sie-Tiong Ha

Civil and Environmental Engineering Faculty Publications

The potential of using ethylenediamine tetraacetic acid modified rice husk (ERH) to remove different types of dyes, namely basic and reactive dyes were studied. Sorption characteristic of ERH showed that it was pH dependent. The kinetics of sorption for both dyes was rapid within the first 60 min regardless of its initial concentration. Using the pseudo-second order kinetics model, the predicted uptakes of Methylene Blue (MB) and Reactive Orange 16 (RO16) agreed closely with experimental values obtained. Three isotherm models were used to fit with equilibrium data, namely Langmuir, Freundlich and BET models. It was found that the equilibrium fitted …

Plutonium - Humic Acid Stability Constant Determination And Subsequent Studies Examining Sorption In The Ternary Pu(Iv) - Humic Acid - Gibbsite System, Trevor Zimmerman

All Theses

Plutonium has been released to the environment through a variety of intentional and unintentional mechanisms, including atmospheric testing, disposition from weapons manufacturing processes, and subsurface disposal. Therefore, a thorough understanding of the chemical, physical, and biological processes affecting plutonium transport is imperative. It has been shown that humic acid (HA) (a refractory component of natural organic matter (NOM)) can effectively solubilize plutonium (Santschi et al., 2002). Increased solubility may result in enhanced subsurface transport, due to the higher concentration of Pu in the aqueous phase. In contrast, the formation of ternary surface complexes may hinder actinide transport. Solution pH is …

Biodegradable Polymer Blends And Composites From Proteins Produced By Animal Co-Product Industry, Bernice Nzioki

All Theses

ABSTRACT
Development of new green materials from by-products of animal rendering industries would provide a substantial economic return to animal rendering processors. Meat and bone meal (MBM), one of the products of the rendering industry, has potential for numerous bio-based applications. This research focuses on fabrication of plastics blends made of MBM (Meat and bone meal) and UHMWPE (ultra high molecular weight polyethylene). We investigated thermal, morphological, water absorption and mechanical properties of the plastics. The plastics were compression molded and their properties were examined.
DSC thermographs of the blends indicated that the thermal properties of UHMWPE did not change …

Renewable Energy Education At Merrimack College, Jack Adams

Electrical Engineering Faculty Publications

This paper describes recent, ongoing and planned Renewable Energy (RE) education at Merrimack College. The primary RE education efforts have been through the department of Electrical Engineering (EE), with involvement from the department of Civil Engineering. In summer of 2009 the college installed a solar hot water (SHW) system in one of its student townhouses. The subjects of the advanced EE elective “Energy Measurement and Display” in summer 2009 were the selection of sensors to measure energy delivered by this SHW unit, and the uploading via Ethernet of real time data to a central server. The EE department requires all …

An Evaluation Of Low Cost Fpga-Based Software Defined Radios For Education And Research, Abhilash M. Purani

Masters Theses and Doctoral Dissertations

The purpose of this study is to evaluate a low-cost Software Defined Radio (SDR) platform for educational and research purposes. An evaluation of existing SDR platforms and design techniques was performed, identifying low cost hardware and software suitable for a laboratory environment. The idea behind the project is to provide undergraduate students with a generic hardware platform so that they can perform simple radio communication experiments. This paper compares and evaluates the existing research projects and educational lab experiments done for SDR. Basic AM and FM radios are created and simulated on the hardware. The detailed procedure to create a …

A Web And Mobile System For Environmental Decision Support, James Carswell, Keith Gardiner, Michela Bertolotto, Andrea Rizzine

Books/Book chapters

Current field data collection methods for many of today’s scientific and other observer/monitor type applications are still entrenched in the “clipboard age”, requiring manual data transcription to a database management system at some (often much) later date, and only allows for visualisation and analysis of recently captured field data “back in the lab”. This chapter is targeted at progressing today’s pen & paper methodology into the spatially enabled mobile computing age of realtime multi-media data input, integration, visualisation, and analysis simultaneously both in the field and the lab. The system described is customized to the specific needs of the Canadian …

Acceleration Of Biomolecular Simulations Using Fpga-Based Reconfigurable Computing, Ananth Nallamuthu

All Theses

A paradigm shift is occurring in the way compute-intensive scientific applications are developed. Thanks to advancements in commercially viable hybrid architectures for High-Performance Computing (HPC), the focus has shifted from improving performance by merely scaling algorithms on von Neumann computing nodes to fully exploiting additional computational capabilities provided by accelerators such as FPGAs (Field Programmable Gate Arrays) and GPGPUs (General Purpose Graphical Processing Units).
Computational chemists use Molecular Dynamics (MD) simulations like LAMMPS (Large Scale Atomic Molecular Massively Parallel Systems) and NAMD (NAnoscale Molecular Dynamics) to simulate biomolecular behaviour such as protein folding and small molecule docking to proteins. MD …

Waste To Work Using Eccrine Sweat Battery Modules To Enhance Pedestrian Safety, Lauren J. Vesty

Renée Crown University Honors Thesis Projects - All

There is a need for increased pedestrian visibility. Improved athletic clothing with built in visibility features would enhance a roadside athlete’s safety. This experiment aims to create such an athletic shirt, while incorporating wearable biotechnology. A sweat battery that produced a voltage of 0.49 V and a current of 5.16 mA was created to power the visibility aspects of the shirt. The battery uses an aluminum anode, a carbon cathode, a sponge block as the container and semi-permeable membrane, and the body’s eccrine sweat as the electrolyte solution. The battery cells were arranged into blocks to produce an optimal current …

Responses Of Problematic Algae To Algaecide Exposures, West Bishop

All Theses

Excessive growths of algae can cause significant disruption of critical water resource usages including: drinking, irrigation, recreation as well as be aesthetically displeasing. Water resource managers are often compelled to take action to mitigate these nuisance algal infestations. Algaecides can be efficient and effective management options to rapidly suppress algal blooms and restore water usages. However, laboratory and field data are required to accurately predict responses to an application as well as potential risks to non-target organisms. Laboratory experiments were used to measure the responses of problematic algae to algaecide exposures and evaluate the margin of safety to sensitive, non-target …

Electrokinetic Manipulation Of Particles And Cells In Microfluidic Devices, Christopher Church

All Theses

With the recent advancement in micro-fabrication technology, lab-on-a-chip devices have been developed in order to perform biological analysis through cell manipulation. Microchannels used in these lab-on-a-chip devices have been demonstrated to accurately perform many different cell manipulation techniques such as focusing, separation, trapping, and lysis. Although there are many methods available for these techniques, electrokinetics has been rapidly gaining popularity due to the simplicity of application and removal of the need for in channel micro-structures. This thesis studies the use of electrokinetic flow and accompanying phenomena in various structured microchannels to perform focusing, separation, trapping, and lysis of cells. Three …

Interpretability Analysis Of Function Structures At Various Levels Of Abstraction: A User Study, Jonathan Thomas

All Theses

Function models are used during the conceptual design phase of the design process to model the intended use or objective of a product, independent of the products physical form. Function models also aid in guiding design activities such as generating concepts and allocating design team resources. Recent research efforts have focused on the formalization of functional models through a controlled vocabulary and archival of functional representations in computer-based repositories. However, the usefulness and interpretability of these function models has not been rigorously evaluated.
This thesis presents the results of two controlled user studies to ascertain the interpretability of functional representations …

Bio-Inspired Distributed Constrained Optimization Technique And Its Application In Dynamic Thermal Management, Saranya Chandrasekaran

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The stomatal network in plants is a well-characterized biological system that hypothetically solves the constrained optimization problem of maximizing CO₂ uptake from the air while constraining evaporative water loss during the process of photosynthesis. There are numerous such constrained optimization problems present in the real world as well as in computer science. This thesis work attempts to solve one such constrained optimization problem in a distributed manner by taking a cue from the dynamics of stomatal networks. The problem considered here is Dynamic Thermal Management (DTM) in a multi-processing element system in computing. There have been several approaches in …

Comparative Studies On Oxygen Mass Transfer For The Design And Development Of A Single-Use Fermentor, Kristan L. Sorenson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Accurate experimental oxygen mass transfer coefficient, a measure of how quickly oxygen travels from a gas bubble to the bulk liquid, is important for comparing performance and for evaluating the oxygen transfer capability of a fermentor. Delays in probe response and changing gas volumes upon start-up of gassing affect the accuracy of oxygen transfer measurements. To mitigate these inaccuracies, a standard correction procedure for oxygen mass transfer data was established for highly oxygenated, well-mixed fermentation systems. Probe response time correction was generated by applying a second-order response model to dissolved oxygen probes and shown to be effective within 4%. By …

Electrospun Scaffolds For Directed Pancreatic Differentiation Of Human Ips Cells, Karl Sonntag

Biological and Agricultural Engineering Undergraduate Honors Theses

In this work, an electrospinning device for fabricating three-dimensional scaffolds was constructed. The device can be used to produce tissue engineered scaffolds electrospun for directing the differentiation of human induced pluripotent stem (iPS) cells into glucose-responsive, insulin-secreting cells for diabetes treatment. Electrospinning utilizes high electrical charge to generate nanofibers from polymers dissolved in solution. A standard setup for such a device includes a high-voltage power source, a syringe pump, and a grounded collector. The process works by dissolving the polymer in a volatile solvent, and filling a syringe with the polymer/solvent mixture. Next, the syringe is locked into place in …

Energy And Nutrient Recovery From Anaerobic Treatment Of Organic Wastes, Christian-Dominik Henrich

All Dissertations

The objective of the research was to develop a complete systems design and predictive model framework of a series of linked processes capable of providing treatment of landfill leachate while simultaneously recovering nutrients and bioenergy from the waste inputs. This proposed process includes an 'Ammonia Recovery Process' (ARP) consisting of: 1) ammonia de-sorption requiring leachate pH adjustment with lime or sodium hydroxide addition followed by, 2) ammonia re-absorption into a 6-molar sulfuric acid spray-tower followed by, 3) biological activated sludge treatment of soluble organic residuals (BOD) followed by, 4) high-rate algal post-treatment and finally, 5) an optional anaerobic digestion process …

Design Of Adaptive Collective Foraging In Swarm Robotic Systems, Hanyi Dai

Dissertations

Inspired by the collective behavior observed in biological colonies, swarm robotics is a new approach to design a distributed control algorithm in order to coordinate a group of simple robots performing a complex group task. With only limited computation and communication ability of individual robots, one of the challenges in designing such multi-robotic systems is to understand the effect of individual robots behavior on the group performance. This thesis dedicates the research to designing a set of local interaction and adaptation rule for individual robots so that optimized collective foraging performance can be achieved at group level.

The research starts …

Optimizing Green Sand Properties Of Fluidized Sand From Aeration And Developing New Green Sand Testing Technique, Ananda Mani Paudel

Dissertations

Aeration sand filling is a new molding technique in foundry. Using this technique, sand with smooth flow can be filled in any orientation and shape using low-pressure air. This is not possible by conventional gravity and high-pressure blow filling techniques. Aeration was introduced as an energy-efficient and environmentally- friendly sand molding technique. In addition, aeration has its niche on quality of molds it could produce. Friability, one of the crucial green properties for the quality mold was significantly low in aeration in comparison to the gravity and high-pressure blow filling. The fluidization action in aeration acted upon the sand clay …