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Processing, Characterization And Performance Of Carbon Nanopaper Based Multifunctional Nanocomposites, Fei Liang

Electronic Theses and Dissertations

Carbon nanofibers (CNFs) used as nano-scale reinforcement have been extensively studied since they are capable of improving the physical and mechanical properties of conventional fiber reinforced polymer composites. However, the properties of CNFs are far away from being fully utilized in the composites due to processing challenges including the dispersion of CNFs and the viscosity increase of polymer matrix. To overcome these issues, a unique approach was developed by making carbon nanopaper sheet through the filtration of well-dispersed carbon nanofibers under controlled processing conditions, and integrating carbon nanopaper sheets into composite laminates using autoclave process and resin transfer molding (RTM). …

Curcumin-Loaded Magnetic Nanoparticles For Breast Cancer Therapeutics And Imaging Applications., Murali M. Yallapu, Shadi F. Othman, Evan Curtis, Nichole A. Bauer, Neeraj Chauhan, Deepak Kumar, Meena Jaggi, Subhash C. Chauhan

All Faculty Articles - School of Engineering and Computer Science

BACKGROUND: The next generation magnetic nanoparticles (MNPs) with theranostic applications have attracted significant attention and will greatly improve nanomedicine in cancer therapeutics. Such novel MNP formulations must have ultra-low particle size, high inherent magnetic properties, effective imaging, drug targeting, and drug delivery properties. To achieve these characteristic properties, a curcumin-loaded MNP (MNP-CUR) formulation was developed.

METHODS: MNPs were prepared by chemical precipitation method and loaded with curcumin (CUR) using diffusion method. The physicochemical properties of MNP-CUR were characterized using dynamic light scattering, transmission electron microscopy, and spectroscopy. The internalization of MNP-CUR was achieved after 6 hours incubation with MDA-MB-231 breast …

Gaining Insight Into The Physics Of Dynamic Atomic Force Microscopy In Complex Environments Using The Veda Simulator, Daniel Kiracofe, John Melcher, Arvind Raman

Birck and NCN Publications

Dynamic atomic force microscopy (dAFM) continues to grow in popularity among scientists in many different fields, and research on new methods and operating modes continues to expand the resolution, capabilities, and types of samples that can be studied. But many promising increases in capability are accompanied by increases in complexity. Indeed, interpreting modern dAFM data can be challenging, especially on complicated material systems, or in liquid environments where the behavior is often contrary to what is known in air or vacuum environments. Mathematical simulations have proven to be an effective tool in providing physical insight into these non-intuitive systems. In …

Eastern Ichigan University Graduate Catalog, 2012-2013, Office Of The Registrar

Graduate Catalogs

No abstract provided.

Optimization Of Bio-Impedance Sensor For Enhanced Detection And Characterization Of Adherent Cells, Dorielle T. Price

USF Tampa Graduate Theses and Dissertations

This research focuses on the detection and characterization of cells using

impedance-based techniques to understand the behavior and response of cells to internal/environmental changes. In combination with impedimetric sensing techniques, the biosensors in this work allow rapid, label-free, quantitative measurements and are very sensitive to changes in environment and cell morphology. The biosensor design and measurement setup is optimized to detect and differentiate cancer cells and healthy (normal) cells. The outcome of this work will provide a foundation for enhanced 3-dimensional tumor analysis and characterization; thus creating an avenue for earlier cancer detection and reduced healthcare costs.

The magnitude of …

Model And Validation Of Static And Dynamic Behavior Of Passive Diamagnetic Levitation For Energy Harvesting, Chamila Shyamalee Siyambalapitiya

USF Tampa Graduate Theses and Dissertations

This dissertation reports the investigation conducted on the static and dynamic behavior of the passive diamagnetic levitation systems.

Attachment of a device to a substrate hinders the optimum performance ability of vibrating devices by altering the dynamic behavior of the moving part whilst introducing higher overall stiffness. The significance of this effect is prominent especially in vibration based energy harvesters as higher stiffness elevates the resonance frequency of the system, making it difficult to tune into ambient low frequencies. Other advantages of the proposed method are given by the removal of mechanical bending elements, which are often the source of …

Research Week 2012, Linda Gardiner

Office of Research Institutional Research and Scholarship

No abstract provided.

Cordyline Fruticosa Growth And Soil Microbial Quality With Topical Application Of Coal Combustion By-Products Aggregates, Sangchul Hwang, Isomar Latorre, Eileen Irizarry

Coal Combustion and Gasification Products Journal Archive

Coal combustion by-products aggregates (CCAs) are a solidified composite of fly and bottom ashes (2:1, by wt). Here, we assessed the feasibility of beneficial use of CCAs as a soil amendment or conditioner by conducting an outdoor experiment with Cordyline fruticosa (lucky plant) to determine its growth and soil microbial quality under the influence of topical CCA application (95 tons ha21). Enhanced growth of C. fruticosa with CCA application was noted, with respect to plant height, growth rate, leaf size, and leaf chlorophyll intensity. Soil dehydrogenase activity and total heterotrophic bacteria count were greater with topical CCA application, especially in …

Mineralogical Transformations In Coal Feedstocks During Carbon Conversion, Based On Packed-Bed Combustor Tests: Part 2. Behavior Of Individual Particles, Ratale H. Matjie, Colin R. Ward, Zhongsheng Li

Coal Combustion and Gasification Products Journal Archive

Handpicked carbon-rich particles (coal or char), mineral-rich particles (heated stones), and bonded stone aggregates (clinkers) from the upper and lower parts of a pilot-scale packed-bed combustor bed, designed to simulate conversion or combustion processes, were subjected to mineralogical and inorganic geochemical studies, in order to evaluate the reactions that may occur during carbon conversion at a particle-by-particle scale. The mineral matter of the carbon-rich particles was found to have higher proportions of carbonate minerals and kaolinite than the mineral-rich (stone) particles in the coal feedstocks used in the study, and to form phases such as anorthite, gehlenite, pyrrhotite, troilite, and …

Mineralogical Transformations In Coal Feedstocks During Carbon Conversion, Based On Packed-Bed Combustor Tests: Part 1. Bulk Coal And Ash Studies, Ratale H. Matjie, Colin R. Ward, Zhongsheng Li

Coal Combustion and Gasification Products Journal Archive

Mineralogical and inorganic geochemical studies have been carried out on composite samples of six different coarse-crushed (,120 mm) feed coals tested in a pilot-scale packed-bed combustor designed to simulate conversion and some fixed-bed combustion processes, and also on composite samples of the ashes produced. The mineral matter of the coals consisted mainly of quartz, kaolinite, and Ca-bearing carbonate minerals (calcite, dolomite, aragonite), with minor proportions of illite, pyrite, and several other phases, along with some Ca in an organically associated form. The base to acid ratio of the coal ashes ranged from 0.1 to 0.3, due mainly to variations in …

Understanding Fracture, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.

An Evaluation Into The Cause Of Corrosive Failure In Autophoretic Coated Material, Sean M. Derrick, Matthew A. Johnson, Gary P. Nola, David Meade Phd, Margaret Joyce Phd

Green Manufacturing Research Journal

This paper documents a study of performance failures in Autophoretic® (A-coat or AP) coatings. As AP is a proprietary process and coating material, limited research has been published regarding the field performance of this coating technique. The specific failure under analysis in this study was corrosion. The study was performed at the request of a manufacturer that was experiencing pre-mature failures in the field on product coated using this process and material. Prepared samples were evaluated using several analysis techniques including, BET Gas Absorption Testing, Optical Microcroscopy, FE-SEM, and Corrosion-Rate Analysis. Samples were subjected to the Society of Automotive Engineers …

Understanding The Role Of Defects In The Radiation Response Of Nanoceria, Amit Kumar

Electronic Theses and Dissertations

Nanoscale cerium oxide (nanoceria) have shown to possess redox active property , and has been widely studied for potential use in catalysis, chemical-mechanical planarization, biomedical and solid oxide fuel cell (SOFC), etc. The redox state of nanoceria can be tuned by controlling the defects within the lattice and thus its physical and chemical properties. Perfect ceria lattice has fluorite structure and the research in last decade has shown that oxide and mixed oxide systems with pyrochlore and fluorite have better structural stability under high energy radiation. However, the current literature shows a limited number of studies on the effect of …

Self-Assmbled Lithography-Free Fabrication Of Microchannels And Microfluidics In Polymers, Wintana Tadesse Kahsai

Bioengineering Theses - Archive

Rapid, reliable and easy to implement approaches are needed for fabrication of circular microchannels in polymeric microfluidics. PDMS has been a choice of material in microfluidics and it is being used as prototype due to its unique property such as flexibility and transparency. Traditional method of fabrication such as photolithography and soft lithography are complicated and time consuming. In this thesis, a non-lithography and bottom-up self-assembled approach is shown. The resulting devices can have uses in many applications such as assays, biosensing, separation of mixtures, micro-mixing and bioreactors. This thesis presents novel approaches of manufacturing self-assembled microchannels in polydimethyleneoxide (PDMS) …

Alignment And Composition Of Laminin-Polycaprolactone Nanofiber Blends Enhance Peripheral Nerve Regeneration, Rebekah A. Neal, Sunil S. Tholpady, Patricia L. Foley, Nathan Swami, Roy C. Ogle, Edward A. Botchwey

School of Medical Diagnostics & Translational Sciences Publications

Peripheral nerve transection occurs commonly in traumatic injury, causing deficits distal to the injury site. Conduits for repair currently on the market are hollow tubes; however, they often fail due to slow regeneration over long gaps. To facilitate increased regeneration speed and functional recovery, the ideal conduit should provide biochemically relevant signals and physical guidance cues, thus playing an active role in regeneration. To that end, laminin and lamininpolycaprolactone (PCL) blend nanofibers were fabricated to mimic peripheral nerve basement membrane. In vitro assays established 10% (wt) laminin content is sufficient to retain neurite-promoting effects of laminin. In addition, modified collector …

Enhanced Killing Effect Of Nanosecond Pulse Electric Fields On Panc1 And Jurkat Cell Lines In The Presence Of Tween 80, Gaurav Basu, Bhargava Subhash Kalluri, Ahmet Can Sabuncu, Christopher J. Osgood, Michael W. Stacey

Bioelectrics Publications

We investigated the effects of nanosecond pulse electric fields (nsPEFs) on Jurkat and PANC1 cells, which are human carcinoma cell lines, in the presence of Tween 80 (T80) at a concentration of 0.18% and demonstarted an enhanced killing effect. We used two biological assays to determine cell viability after exposing cells to nsPEFs in the presence of T80 and observed a significant increase in the killing effect of nsPEFs. We did not see a toxic effect of T80 when cells were exposed to surfactant alone. However, we saw a synergistic effect when cells exposed to T80 were combined with the …

Probing Nanoparticle Interactions In Cell Culture Media, Ahmet C. Sabuncu, Janna Grubbs, Shizhi Qian, Tarek M. Abdel-Fattah, Michael W. Stacey, Ali Beskok

Bioelectrics Publications

Nanoparticle research is often performed in vitro with little emphasis on the potential role of cell culture medium. In this study, gold nanoparticle interactions with cell culture medium and two cancer cell lines (human T-cell leukemia Jurkat and human pancreatic carcinoma PANC1) were investigated. Gold nanoparticles of 10, 25, 50, and 100 nm in diameter at fixed mass concentration were tested. Size distributions and zeta potentials of gold nanoparticles suspended in deionized (DI) water and Dulbecco's Modified Eagle's Media (DMEM) supplemented with fetal calf serum (FCS) were measured using dynamic light scattering (DLS) technique. In DI water, particle size distributions …

The Use Of An In Vitro 3d Melanoma Model To Predict In Vivo Plasmid Transfection Using Electroporation, Benadette Marrero, Richard Heller

Bioelectrics Publications

A large-scale in vitro 3D tumor model was generated to evaluate gene delivery procedures in vivo. This 3D tumor model consists of a "tissue-like" spheroid that provides a micro-environment supportive of melanoma proliferation, allowing cells to behave similarly to cells in vivo. This functional spheroid measures approximately 1 cm in diameter and can be used to effectively evaluate plasmid transfection when testing various electroporation (EP) electrode applicators. In this study, we identified EP conditions that efficiently transfect green fluorescent protein (GFP) and interleukin 15 (IL-15) plasmids into tumor cells residing in the 3D construct. We found that plasmids …

Macro And Microfluidic Flows For Skeletal Regenerative Medicine, Brandon D. Riehl, Jung Yul Lim

Department of Mechanical and Materials Engineering: Faculty Publications

Fluid flow has a great potential as a cell stimulatory tool for skeletal regenerative medicine, because fluid flow-induced bone cell mechanotransduction in vivo plays a critical role in maintaining healthy bone homeostasis. Applications of fluid flow for skeletal regenerative medicine are reviewed at macro and microscale. Macroflow in two dimensions (2D), in which flow velocity varies along the normal direction to the flow, has explored molecular mechanisms of bone forming cell mechanotransduction responsible for flow-regulated differentiation, mineralized matrix deposition, and stem cell osteogenesis. Though 2D flow set-ups are useful for mechanistic studies due to easiness in in situ and post-flow …

Kentucky Water Resources Research Institute Annual Technical Report Fy 2011, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY2011 Annual Technical Report for Kentucky consolidates reporting requirements for the Section 104(b) base grant award into a single document that includes; 1) a synopsis of each research project that was conducted during the period, 2) citations for related publications, reports, and presentations, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable awards and achievements during the year.

Project 2011KY166B (Sewage to fertilizer: a proposed solution to water pollution) was not initiated because the principal investigator (Dr. Rebecca Evans Kelley) resigned from the Department of Biological Sciences at …

Timing Of Residential Electric Loads To Reduce Air Emissions From Power Generation, Michelle Marinich Rogers

Wayne State University Theses

Over the course of a day, power utilities must respond to changing demand by dispatching or shedding output from different generators. Each generator is associated with a unique profile of air emissions, based on the type of fuel consumed, installed pollution controls, and the generator's efficiency. The aim of this study is to determine whether shifting electric demand to times when cleaner generation sources are available would result in overall emissions reduction.

Dynamic wholesale pricing in the electric power market, specifically the Locational Marginal Price (LMP), provides a means to estimate the marginal generator fuel type. This knowledge was used …

The Influence Of Membrane Cholesterol-Related Shear Stress Mechanosensitivity On Neutrophil Flow Behavior, Xiaoyan Zhang

Theses and Dissertations--Biomedical Engineering

Hypercholesterolemia is a dominant risk factor for a variety of cardiovascular diseases and involves a chronic inflammatory component in which neutrophil activity plays a critical role. Recently, fluid shear stress mechanotransduction has been established as a control mechanism that regulates the activity of neutrophils by reducing the formation of pseudopods and the surface expression of CD18 integrins, thereby rendering these cells rounded, deformable, and non-adhesive. This is critical for maintaining a healthy circulation, because chronically activated neutrophils not only release excess cytotoxic and degradative agents but also exhibit a reduced efficiency to pass through the small vessels of the microcirculation …

Test 2043: John Deere 9510rt, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2039: John Deere 9410r, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Test 2032a: Challenger Mt595b, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Nebraska Summary: S868 Massey Ferguson 8660, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Nebraska Summary: S845 Challenger Mt585d, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Nebraska Summary: S841 Massey Ferguson 7624, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Nebraska Summary: S838 Massey Ferguson 7619, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …

Consensus-Type Stochastic Approximation Algorithms, Yu Sun

Wayne State University Dissertations

This work is concerned with asymptotic properties of consensus-type algorithms for networked systems whose topologies switch randomly. The regime-switching process is modeled as a discrete-time Markov chain with a nite state space. The consensus control is achieved by designing stochastic approximation algorithms. In the setup, the regime-switching process (the Markov chain) contains a rate parameter

"Ε> 0 in the transition probability matrix that characterizes how frequently the topology switches. On the other hand, the consensus control algorithm uses a step-size Μ that denes how fast the network states are updated. Depending on their relative values, three distinct scenarios emerge. Under …