PdmsStar-Peg Hydrogels Prepared Via Solvent-Induced Phase Separation (Sips) And Their Potential Utility As Tissue Engineering Scaffolds, B. M. Bailey, R. Fei, Dany J. Munoz Pinto, M. S. Hahn, M. A. Grunlan

Engineering Faculty Research

Inorganic-organic hydrogels based on methacrylated star polydimethylsiloxane (PDMS_star-MA) and diacrylated poly(ethylene glycol) (PEG-DA) macromers were prepared via solvent-induced phase separation (SIPS). The macromers were combined in a dichloromethane precursor solution and sequentially photopolymerized, dried and hydrated. The chemical and physical properties of the hydrogels were further tailored by varying the number average molecular weight (M_n) of PEG-DA (M_n = 3.4k and 6k g mol^-1) as well as the weight percent ratio of PDMS_star-MA (M_n = 7k g mol^-1) to PEG-DA from 0:100 to 20:80. Compared to analogous hydrogels …

Estimation Of Solute Fluxes From Ungaged Headwater Catchments In The Catskill Park Of New York State, Chris Gianfagna

Civil and Environmental Engineering - Theses

Predictions of flow and subsequent solute fluxes from ungaged basins have important implications both for water resources management and ecosystem monitoring studies. The Catskill region of New York State is one such place that requires both water resources management and ecosystem monitoring due to its strategic location as the main water-supplying region for New York City. This study examines the differences in chemical mass flux estimates made in ungaged basins using three different chemistry aggregation methods for solute concentrations determined from monthly grab samples. The efficacy of area ratios for predicting flow at the upstream location of a nested pair …

Long-Term Integrated Studies Show Complex And Surprising Effects Of Climate Change In The Northern Hardwood Forest, Peter M. Groffman, Charles T. Driscoll, Chris E. Johnson, Lindsey E. Rustad, Pamela H. Templer

Civil and Environmental Engineering - All Scholarship

Evaluations of the local effects of global change are often confounded by the interactions of natural and anthropogenic factors that overshadow the effects of climate changes on ecosystems. Long-term watershed and natural elevation gradient studies at the Hubbard Brook Experimental Forest and in the surrounding region show surprising results demonstrating the effects of climate change on hydrologic variables (e.g., evapotranspiration, streamflow, soil moisture); the importance of changes in phenology on water, carbon, and nitrogen fluxes during critical seasonal transition periods; winter climate change effects on plant and animal community composition and ecosystem services; and the effects of anthropogenic disturbances and …

Creating Tomorrow, Fall 2012, College Of Engineering

College of Engineering Magazines

Annual magazine for the College of Engineering at Utah State University.

Silica Nanoparticle-Based Coatings With Superhydrophilic And Superhydrophobic Properties, Robert Andrew Fleming

Graduate Theses and Dissertations

Superhydrophilic and superhydrophobic surfaces have potential for implementation into a variety of fields, including self-cleaning surfaces, anti-fogging transparent materials, and biomedical applications. In this study, sandblasting, oxygen plasma treatments, silica nanoparticle films, and a low surface energy fluorocarbon film were employed to change the natural surface wettability of titanium, glass, and polyethylene terephthalate (PET) substrates, with an aim to produce superhydrophilic and superhydrophobic behavior. The effects of these surface modifications are characterized by water contact angles (WCAs), surface wetting stability, surface morphology and roughness, surface elemental composition, and optical transmittance measurements. The results show that stable superhydrophilic and superhydrophobic surfaces …

Design, Fabrication, Testing Of Cnt Based Isfet And Characterization Of Nano/Bio Materials Using Afm, Zhuxin Dong

Graduate Theses and Dissertations

A combination of Carbon Nanotubes (CNTs) and Ion Selective Field Effect Transistor (ISFET) is designed and experimentally verified in order to develop the next generation ion concentration sensing system. Micro Electro-Mechanical System (MEMS) fabrication techniques, such as photolithography, diffusion, evaporation, lift-off, packaging, etc., are required in the fabrication of the CNT-ISFET structure on p-type silicon wafers. In addition, Atomic Force Microscopy (AFM) based surface nanomachining is investigated and used for creating nanochannels on silicon surfaces. Since AFM based nanomanipulation and nanomachining is highly controllable, nanochannels are precisely scratched in the area between the source and drain of the FET where …

Comprehensive Drainage Study Of The Upper Reach Of College Branch In Fayetteville, Arkansas, Kathryn Lea Mccoy

Graduate Theses and Dissertations

College Branch is a stream with headwaters located on the University of Arkansas campus. The stream flows through much of the west side of campus, gaining discharge and enlarging its channel as it meanders to the south. College Branch has experienced erosion and flooding issues in recent years due to increased urbanization of its watershed and increased runoff volume.

The purpose of this project was to develop a comprehensive drainage study of College Branch on the University of Arkansas campus. Storm runoff and flood flow patterns were evaluated in order to understand the hydraulics and hydrology of the watershed and …

Application Of Response Surface Methodology And Central Composite Design For 5p12-Rantes Expression In The Pichia Pastoris System, Frank M. Fabian

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Pichia pastoris has demonstrated the ability to express high levels of recombinant heterologous proteins. Protein expression is enhanced during fermentation at high cell density. However, the level of expression is mainly regulated by fermentation operation factors. This research is directed to investigate the effect of methanol growth rate, temperature and pH in the expression of the total 5P12-Rantes concentration, expression of active 5P12-Rantes and Specific yield using the response surface methodology and central composite design.

The response surface methodology, RSM, has been used successfully used by Zhang, W. and Ian, M. to optimize the cell density and fermentation process. The …

Syntheses, Characterization, And Applications Of Injectable Citrate-Based Mussel-Inspired Biodegradable Adhesive (Icmba) Polymers And Hydrogels, Mohammadreza Mehdizadeh

Material Science and Engineering Dissertations - Archive

Tissue adhesives are increasingly gaining more popularity in various areas of biomedical applications. They are utilized as surgical adhesives, as a replacement or adjunct to conventional wound closure and bleeding control techniques such as suturing, as well as in other applications such as tissue engineering and drug delivery.Unfortunately, the existing surgical adhesives are not ideal for wet tissue adhesion required in many surgeries such as those for internal organs. Developing surgical adhesives with strong wet tissue adhesion, controlled degradability and mechanical properties, and excellent biocompatibility has been a significant challenge. Herein, learning from nature, we report a one-step synthesis of …

Phenomenological Modeling Of Image Irradiance For Non-Lambertian Surfaces Under Natural Illumination., Shireen Y. Elhabian

Electronic Theses and Dissertations

Various vision tasks are usually confronted by appearance variations due to changes of illumination. For instance, in a recognition system, it has been shown that the variability in human face appearance is owed to changes to lighting conditions rather than person's identity. Theoretically, due to the arbitrariness of the lighting function, the space of all possible images of a fixed-pose object under all possible illumination conditions is infinite dimensional. Nonetheless, it has been proven that the set of images of a convex Lambertian surface under distant illumination lies near a low dimensional linear subspace. This result was also extended to …

Note: A Transimpedance Amplifier For Remotely Located Quartz Tuning Forks, Ethan Kleinbaum, Gabor Csathy

Birck and NCN Publications

The cable capacitance in cryogenic and high vacuum applications of quartz tuning forks imposes severe constraints on the bandwidth and noise performance of the measurement. We present a single stage low noise transimpedance amplifier with a bandwidth exceeding 1 MHz and provide an in-depth analysis of the dependence of the amplifier parameters on the cable capacitance. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4769271]

Machining Stability Of Wire Edm Of Titanium, Farnaz Nourbakhsh

Department of Industrial and Management Systems Engineering: Dissertations, Theses, and Student Research

This work presents an experimental investigation of wire electro-discharge machining (WEDM) of titanium alloy. The outstanding characteristics of titanium alloys such as their compatibility and noticeable physical, mechanical and biological performances has led to increased application of them in various industries especially in biomedical industries over the last 50 years. However, due to low thermal conductivity of titanium and its alloys and their reactivity with cobalt in most tool materials, there are some difficulties in machining titanium and its alloys by conventional machining. On the other hand, unconventional machining processes especially Wire Electrical Discharge Machining (WEDM) are more appropriate techniques …

Low Cost Neurochairs, Frankie Pike

Master's Theses

Electroencephalography (EEG) was formerly confined to clinical and research settings with the necessary hardware costing thousands of dollars. In the last five years a number of companies have produced simple electroencephalograms, priced below $300 and available direct to consumers. These have stirred the imaginations of enthusiasts and brought the prospects of "thought-controlled" devices ever closer to reality. While these new devices were largely targeted at video games and toys, active research on enabling people suffering from debilitating diseases to control wheelchairs was being pursued. A number of neurochairs have come to fruition offering a truly hands-free mobility solution, but whether …

Effects Of Seawater On The Mechanical Behavior Of Composite Sandwich Panels Under Monotonic Shear Loading, Thomas Robert Woo

Master's Theses

Abstract

Salt water environments are very harsh on materials that are used within them. Many issues are caused by either corrosion and/or internal degradation to the materials themselves. Composites are better suited for this environment due to their high strength to weight ratios and their corrosion resistance, but very little is known about the fracture mechanics of composites. The goal of this study is to gain a better understanding for the behavior of a composite boat hull under a shear loading, similar to the force water applies on the hull as the boat moves through the water; then attempt to …

Bioflocculation Of Wastewater Treatment Pond Suspended Solids, Louis Lefebvre

Master's Theses

Bioflocculation of Wastewater Treatment Pond Suspended Solids

Louis Lefebvre

Wastewater treatment lagoons and high rate algae ponds (HRAPs) can provide cost effective wastewater treatment, but they commonly have high effluent concentrations of total suspended solids (TSS). In this thesis algae pond effluent was treated in a beaker testing apparatus (mixed and aerated) with various mixtures of activated sludge and primary effluent simulating differing activated sludge aeration basin compositions then was allowed to settle to assess settleability. Conventionally, microalgal suspended solids are removed by chemical coagulation followed by separation methods that often have a high cost relative to the low cost …

Performance Of A Wastewater Treatment Pond System With Microfiltration, Eric Todd Martin

Master's Theses

ABSTRACT

PERFORMANCE OF A WASTEWATER TREATMENT POND SYSTEM WITH

MICROFILTRATION

Eric Martin

The Woodlands Wastewater Treatment Plant (WWWTP) treats wastewater from the Woodlands housing community near Nipomo, California. The treated effluent is recycled for irrigation of a golf course within the community. The treatment facility consists of three facultative ponds in series followed by a microfiltration system and chlorine disinfection. Microfiltration of wastewater pond effluent is a fairly new, and potentially challenging, application of microfiltration. This thesis describes the operating conditions and behavior of the WWWTP pond system followed by a microfiltration system for the purpose of producing recyclable water …

Synthesis And Characterization Of Nanoscale Fluorescent Polymer Films, Maryus Chyasnavichyus

All Dissertations

Performance of the chemical sensing devices is based sensitivity to the targeted analytes and accuracy of the measurements. Of many different types of chemical sensors, fluorescence based sensing devices draw much attention as efficient yet small and straightforward devices, capable of detection of various analytes at extremely small quantities.
Polymeric materials provide support for the fluorescent materials and usually serve as a host for the chromophores, protecting them from harsh environments, and serve as a transport media for the analyte.
In the present study thin fluorescent polymer films, sensitive to the environment are synthesized and studied. Poly(glycidyl methacrylate) was used …

Induced Elastic Matrix Synthesis Within 3-Dimensional Collagen Constructs, Lavanya Venkataraman

All Dissertations

Elastin, a primary component of elastic arteries, maintains structural stability of the cyclically recoiling artery, and critically regulates vascular cell behavior. Accelerated degradation of elastic matrix, such as that seen in vascular pathologies like abdominal aortic aneurysms (AAA), can therefore severely compromise vessel homeostasis. Tissue engineering and in-situ matrix repair strategies evaluated so far are primarily limited in inducing adult vascular cells to replicate the complex elastic matrix assembly process, and restore lost matrix integrity. Previously, our lab established the elastogenic benefits of concurrent delivery of TGF-β1 and HA-oligomers (together termed elastogenic factors, EFs), within 2D cultures of rat aortic …

Measuring Impedance Of Tissues Using A Microfabricated Microelectrode Array, Ashwini Bhat

Master's Theses

MEASURING IMPEDANCE OF TISSUES USING A MICROFABRICATED MICROELECTRODE ARRAY By Ashwini Bhat

This thesis looks at the possibility of using impedance spectroscopy for differentiating tissue, using a microelectrode array (MEA). The thesis first discusses the background and the motivation for this thesis. It covers the certain basic concepts of the human skin starting from the top epidermis layer all the way to the deep dermis layers of the skin. Then it discusses different types of skin cancer and how they occur, in humans. It also discusses various microfabrication techniques such as oxidation, wet etching, sputtering and photolithography for the creation …

Engineering Titanium Dioxide Nanoparticles For Bacterial Biofilm Treatment, Massado Ngompe, Yu Hsin Tsai, Nathalie Milbrandt, Zhuoying Jiang, Xiong Yu, Anna Cristina S. Samia

Intersections Fall 2020

Titanium dioxide nanoparticles (TiO2 NPs) are non-toxic and biocompatible materials that are used for a wide range of applications such as pigments, sunscreens, cosmetics, and food colorings. TiO2 possesses a large band gap (3.2 eV) which, by heteroatom doping or by molten salt/hydrogen assisted reduction, can be narrowed to allow for activity within the visible light spectrum making them optimal candidates for use in bacterial biofilm eradication. Nitrogen-doped and reduced TiO2 NPs have been explored in this study due to their narrowed band gap. The narrowed band gap allows for the formation of excitons upon the absorption of light within …

Modeling Of Yeast Pheromone Pathway Using Petri Nets, Abhishek Majumdar

School of Computing: Dissertations, Theses, and Student Research

Yeast (Saccharomyces cerevisiae) is one of the most widely studied single celled organisms. Mating of yeast cells occur between cells of opposite mating types a and alpha. Pheromone secretion by a cell alerts the corresponding opposite type cell about its presence and eventually facilitates the process of mating between them. The details of how pheromones affect cells can be studied from the pheromone response pathway in a yeast cell. A response pathway typically depicts the chain of interactions that happens between the different proteins in the cells in response to the pheromone. In this thesis we model the …

Microbiologically Enhanced Mixing Across Scales During In-Situ Bioremediation Of Uranium, Reinaldo E. Alcalde

McNair Scholars Research Journal

Production of nuclear fuels for weapons and electric energy has resulted in groundwater uranium contamination at Department of Energy (DOE) sites. Reduction of uranium by dissimilatory metal-reducing bacteria (DMRB) is an effective approach for in-situ bioremediation of these sites. In this process, an organic electron donor is typically delivered through a well into groundwater in order to promote the biological reduction of soluble and toxic U(VI) to insoluble and less toxic U(IV). A key challenge is mixing the organic electron donor with U(VI) in groundwater where laminar flow conditions prevail. A potential solution is to enhance reaction beyond the scale …

Functional Classification Of Skeletal Muscle Networks. I. Normal Physiology, Yu Wang, John Winters, Shankar Subramaniam

Biomedical Engineering Faculty Research and Publications

Extensive measurements of the parts list of human skeletal muscle through transcriptomics and other phenotypic assays offer the opportunity to reconstruct detailed functional models. Through integration of vast amounts of data present in databases and extant knowledge of muscle function combined with robust analyses that include a clustering approach, we present both a protein parts list and network models for skeletal muscle function. The model comprises the four key functional family networks that coexist within a functional space; namely, excitation-activation family (forward pathways that transmit a motoneuronal command signal into the spatial volume of the cell and then use Ca …

Building Envelope Wind Pressure Manipulation For Application In Streamlined High-Rise Buildings, Sivaramprasad Sivakumar

Mechanical and Aerospace Engineering - Dissertations

This research investigates methods of manipulating building envelope wind pressure distribution for application in the natural ventilation of high-rise buildings. CFD simulations are employed to predict the wind pressure distribution around the building envelope. First, a 2-D CFD study is conducted to explore various techniques of manipulating the building envelope wind pressure distribution. This study indicates that the use of externally mounted flow-resistance devices is an effective method of manipulating the wind pressure distribution. It is demonstrated that this technique is well suited for application to buildings of streamlined cross-section (e.g. elliptical planform). Next, a 3-D CFD study is conducted …

Cytoskeletal Strains In Modeled Optohydrodynamically Stressed Healthy And Diseased Biological Cells, Sean S. Kohles, Yu Liang, Asit K. Saha

Mechanical and Materials Engineering Faculty Publications and Presentations

Controlled external chemomechanical stimuli have been shown to influence cellular and tissue regeneration/degeneration, especially with regards to distinct disease sequelae or health maintenance. Recently, a unique three-dimensional stress state was mathematically derived to describe the experimental stresses applied to isolated living cells suspended in an optohydrodynamic trap (optical tweezers combined with microfluidics). These formulae were previously developed in two and three dimensions from the fundamental equations describing creeping flows past a suspended sphere. The objective of the current study is to determine the full-field cellular strain response due to the applied three-dimensional stress environment through a multiphysics computational simulation. In …

Development Of Core Body Temperature (Cbt) And Heart Rate Wearable Device, Brenna Carbone, Madison Castellanos, Jonathan Chen, Jenna Wagner

Intersections Fall 2020

Hyperthermia is a condition when the body's heat-regulation system is overwhelmed and a person's core body temperature (CBT) is above 100.4°F (38°C). This is a major risk among athletes and occupational workers in the military, construction, manufacturing, and emergency response who engage in intense physical activity. Currently the gold standard to measure CBT is through a rectal thermometer. While rectal thermometers are accurate, they are quite invasive and do not provide a way for continuous monitoring. Other skin and oral thermometers which are considered noninvasive are not accurate because they only measure surface temperature and are easily influenced by other …

"Apps"—An Innovative Way To Share Extension Knowledge, Joseph S. Dvorak, Tanya C. Franke-Dvorak, Randy R. Price

Biosystems and Agricultural Engineering Faculty Publications

Extension professionals across the country are continuously seeking innovative ways to reach clientele and to disseminate timely, educational information. A new avenue to reach clientele includes the use of smartphone "apps." The "Machinery Sizing" app, which was developed to ease the estimation of tractor horsepower to implement sizing for Extension clientele anytime, anywhere, is explained as a key example for Extension professionals to utilize apps in disseminating information to clientele. There are many benefits to using apps, including information availability wherever Internet service is available on the smartphone, ease of computations of equations, and automatic updates being sent to users.

Morphometric, Biochemical, And Raman Spctral Analyses Of Muscle Damage In Patients With Peripheral Arterial Disease: Provising Objective Criteria For Diagnosis And Treatment Monitoring, Kim Cluff

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Peripheral arterial disease (PAD), which affects approximately 10 million Americans, is characterized by atherosclerosis of the non-coronary arteries. PAD produces a progressive accumulation of ischemic injury to the limbs that is reflected in a gradual worsening in the myofiber morphology and oxidative damage in the gastrocnemius muscle. In this study, we evaluated the hypothesis that quantitative morphological and biochemical parameters of gastrocnemius myofibers change in a consistent manner during the progression of PAD, provide an objective grading of muscle degeneration in the ischemic limb, and correlate to clinical stage of PAD. Myofiber morphometrics were determined precisely with mathematical equations that …

Biodiesel Production From Mixed Culture Algae Via A Wet Lipid Extraction Procedure, Ashik Sathish

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Development of renewable sources of energy has received significant interest due to the rising costs of energy and the environmental impact of using fossil fuels. Biodiesel production from renewable sources of oil has shown promise of helping to replace or reduce dependence on petroleum based diesel thereby reducing demand for crude oil. Microalgae have been considered as a strong candidate for the production of large quantities of renewable oil for biodiesel production.

Microalgae are single cell photosynthetic organisms that posses the capability to produce renewable oil at rates much faster than land based plants and crops. In addition, microalgae can …

Extending The Battery-Powered Operating Time Of A Wireless Environmental Monitoring System, Ross Matthew Butler

Boise State University Theses and Dissertations

Advances in low-power microelectronics and sensor technologies have enabled the creation of sophisticated environmental monitoring systems capable of operating on battery power. Independence from a power outlet connection opens up many new potential applications, but limited battery life still imposes significant restrictions on a monitoring system’s capabilities and the number of systems that can be economically deployed and maintained. These restrictions have motivated much research into reducing monitoring system energy usage, increasing battery capacity, and harnessing alternative energy sources. While most of the research focuses on new system design, there is a need for techniques to extend the battery-powered operating …