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Insect Wing Flexibility Improves The Aerodynamic Performance Of Small Revolving Wings, Gal Ribak, Ori Stearns, Kiruthika Sundararajan, Duvall Dickerson-Evans, Dana Melamed, Maya Rabinovich, Roi Gurka Mar 2025

Insect Wing Flexibility Improves The Aerodynamic Performance Of Small Revolving Wings, Gal Ribak, Ori Stearns, Kiruthika Sundararajan, Duvall Dickerson-Evans, Dana Melamed, Maya Rabinovich, Roi Gurka

Physics and Engineering Science

Insect wings are flexible, elastically deforming under loads experienced during flapping. The adaptive value of this flexibility was tested using a revolving wing set-up. We show that the wing flexibility of the beetle Batocera rufomaculata, suppresses the reduction in lift coefficient that is expected to occur with a reduction of wing size compared to rigid propeller blades. Moreover, the scaling of wing flexibility with size is intra-specifically tuned through changes in wing-vein cross-section, resulting in smaller wings achieving proportionally larger chordwise deformations compared to larger wings, when loaded with aerodynamic forces. These elastic deformations control the separation of flow from …


The Artificial Intelligence-Enhanced Echocardiographic Detection Of Congenital Heart Defects In The Fetus: A Mini-Review, Khadiza Tun Suha, Hugh Lubenow, Stefania Soria-Zurita, Marcus Haw, Joseph Vettukattil, Jingfeng Jiang Mar 2025

The Artificial Intelligence-Enhanced Echocardiographic Detection Of Congenital Heart Defects In The Fetus: A Mini-Review, Khadiza Tun Suha, Hugh Lubenow, Stefania Soria-Zurita, Marcus Haw, Joseph Vettukattil, Jingfeng Jiang

Michigan Tech Publications

Artificial intelligence (AI) is rapidly gaining attention in radiology and cardiology for accurately diagnosing structural heart disease. In this review paper, we first outline the technical background of AI and echocardiography and then present an array of clinical applications, including image quality control, cardiac function measurements, defect detection, and classifications. Collectively, we answer how integrating AI technologies and echocardiography can help improve the detection of congenital heart defects. Particularly, the superior sensitivity of AI-based congenital heart defect (CHD) detection in the fetus (>90%) allows it to be potentially translated into the clinical workflow as an effective screening tool in …


A Case Study Of Gray-Box Fuzzing With Byte- And Tree-Level Mutation Strategies In Xml-Based Applications For Exposing Security Vulnerabilities, Şerafetti̇n Şentürk, Vahi̇d Garousi, Nejat Yumuşak Mar 2025

A Case Study Of Gray-Box Fuzzing With Byte- And Tree-Level Mutation Strategies In Xml-Based Applications For Exposing Security Vulnerabilities, Şerafetti̇n Şentürk, Vahi̇d Garousi, Nejat Yumuşak

Turkish Journal of Electrical Engineering and Computer Sciences

Fuzzing is an automated process for detecting crashes and vulnerabilities in software system and it is classified as grammar- or mutation-based in terms of input generation. While the grammar-based fuzzing generates inputs from a specification and takes highly-structured inputs, mutation-based fuzzing generates inputs by modifying input files and abstract syntax trees randomly. There are not many case studies comparing the crash detection capabilities in the scope of mutation-based fuzzing. To add to the body of empirical evidence in this area, this case study compares fuzzing with different mutation strategies to evaluate their effectiveness in three aspects: fault detection effectiveness, fault …


Multikernel Embedded Fusion Unet (Mkef-Unet): A Robust Deep Learning Approach For Accurate Segmentation Of Chagas Parasites, Preet Kumar, Carlos Brito-Loeza, Lavdie Rada Mar 2025

Multikernel Embedded Fusion Unet (Mkef-Unet): A Robust Deep Learning Approach For Accurate Segmentation Of Chagas Parasites, Preet Kumar, Carlos Brito-Loeza, Lavdie Rada

Turkish Journal of Electrical Engineering and Computer Sciences

This paper introduces a novel approach for segmenting Chagas parasites on stained blood smear samples from mice during the acute phase of infection with Trypanosoma cruzi utilizing a U-Net-based deep learning model named multikernel embedded fusion UNet (MKEF-UNet). Our proposed model incorporates DenseNet-121 for feature extraction, a classifier module for predicting parasite information, and a segmentation decoder with multiscale feature fusion to generate precise segmentation results. Notably, the integration of the embedded vector module, multikernel convolutions with dilations, and advanced data augmentation techniques significantly enhance the model’s robustness and generalization capabilities. In extensive experiments on the Chagas dataset, MKEF-UNet achieves …


Novel Method For Pure Polymer Vagus Nerve Stimulators, James Dodge Iii Mar 2025

Novel Method For Pure Polymer Vagus Nerve Stimulators, James Dodge Iii

ENGS 88 Honors Thesis (AB Students)

Vagus nerve stimulation (VNS) has become a promising treatment for epilepsy, depression, obesity, and more. However, the state-of-the-art nerve cuffs use metal conductors, limiting the implanted VNS devices’ biocompatibility, electronic properties, and ultimately the device lifetime. Because the benefits of VNS treatment increase over time, and metal limits the lifetime of devices, a transition to non-metallic conductors with a better match to tissue material properties and safer electronic properties promises to increase the lifetime of VNS devices. To demonstrate the replacement of metal with a conductor with properties closer to that of body tissue, a novel fabrication scheme was designed …


Raising Awareness About Hydrographic Careers Through Sea-Going Opportunities, Juliet Kinney, Rochelle Wigley, Sara Cardigos, Fahima Bellabad, Larissa Marques Freguette Mar 2025

Raising Awareness About Hydrographic Careers Through Sea-Going Opportunities, Juliet Kinney, Rochelle Wigley, Sara Cardigos, Fahima Bellabad, Larissa Marques Freguette

Center for Coastal and Ocean Mapping

There is a worldwide shortage of hydrographic personnel (van Wegen, 2021, Hydro International 2008).  Calls for action to address this issue include the IHO’s Hydrography at Sea opportunities, while intiatiative such as Seabed 2030 are bringing broader attention to the field and helping to catalyze new discussions and partnerships in hydrography (IHO, 2024).  The global sea floor mapping community needs to develop a broader workforce pipeline.  We would like to highlight the importance of providing time at sea and leadership opportunities in developing a robust workforce.  We start with an overview of a selection of current exchange and training programs …


Investigating Spatial Mapping Of Lipid And Protein Alterations Within Cells And Tissues Using Raman Microspectroscopy, Elnaz Sheikh Mar 2025

Investigating Spatial Mapping Of Lipid And Protein Alterations Within Cells And Tissues Using Raman Microspectroscopy, Elnaz Sheikh

LSU Doctoral Dissertations

The progression of various diseases is associated with alterations in the microenvironment of cells, consisting of a variety of metabolites like lipids and proteins. It is well known that lipids and proteins are potential biomarkers for indicating alterations within the cell microenvironment induced by disease, and various methods are frequently used for their examination. To understand the chemical composition and spatial distribution of constituents in tissues and cells, confocal Raman spectroscopy and microscopy, as non-destructive tools, have shown potential for monitoring abnormalities at the cellular level with high resolution and can facilitate detection through targeting multiple biomarkers. The application of …


Physical And Biological Effects On Moths’ Navigation Performance, Yiftach Golov, Roi Gurka, Alexander Liberzon, Ally Harari Mar 2025

Physical And Biological Effects On Moths’ Navigation Performance, Yiftach Golov, Roi Gurka, Alexander Liberzon, Ally Harari

Physics and Engineering Science

In a chemosensing system, the local olfactory environment experienced by a foraging organism is defined as an odorscape. Using the nocturnal pink bollworm moth (Pectinophora gossypiella), we tested the combined effect of three biophysical aspects in its immediate odorscape to shed light on the coupling effects of biotic and abiotic factors on navigation performances of a nocturnal forager: i) the quality of the pheromone source, ii) the pheromone availability, and iii) the airflow characteristics. The navigation performance of the males was investigated using a wind tunnel assay equipped with 3D infrared high-speed cameras. The navigation performance of the males was …


Feature Manifold Transformer For Detection Of Differential Item Functioning: Visual Detection Of Categorical Feature Nonconformity Through Attention-Based Analysis, Derrick A. Cox, Tanvi Banerjee, William L. Romine Mar 2025

Feature Manifold Transformer For Detection Of Differential Item Functioning: Visual Detection Of Categorical Feature Nonconformity Through Attention-Based Analysis, Derrick A. Cox, Tanvi Banerjee, William L. Romine

Computer Science and Engineering Faculty Publications

Methods for interpreting complex feature interactions in educational assessment data remain a critical challenge, with traditional statistical approaches often creating barriers to accessibility and interpretability. We introduce the Feature Manifold Transformer (FMT), a novel machine learning approach that leverages dimensionality reduction, representation learning, and transformer architectures to visualize and interpret feature relationships in categorical data. Using the Concept Inventory of Natural Selection (CINS) and Concept Assessment of Natural Selection (CANS) datasets as testbeds, we demonstrate the FMT’s ability to capture subtle relationships between student demographics and response patterns. Our methodology enables both global and local pattern analysis, providing interpretable visualizations …


Msbzip55 Regulates Salinity Tolerance By Modulating Melatonin Biosynthesis In Alfalfa, Tingting Wang, Jiaqi Yang, Jiamin Cao, Qi Zhang, Huayue Liu, Peng Li, Yizhi Huang, Wenwu Qian, Xiaojing Bi, Hui Wang, Yunwei Zhang Mar 2025

Msbzip55 Regulates Salinity Tolerance By Modulating Melatonin Biosynthesis In Alfalfa, Tingting Wang, Jiaqi Yang, Jiamin Cao, Qi Zhang, Huayue Liu, Peng Li, Yizhi Huang, Wenwu Qian, Xiaojing Bi, Hui Wang, Yunwei Zhang

Faculty Publications

No abstract provided.


Synthesis, Characterization And Delamination Studies Of Metallic Thin Films Prepared Using Sputtering And Ebeam Evaporation Methods, Anoop Joseph Mar 2025

Synthesis, Characterization And Delamination Studies Of Metallic Thin Films Prepared Using Sputtering And Ebeam Evaporation Methods, Anoop Joseph

USF Tampa Graduate Theses and Dissertations

In many mechanical applications, including the manufacturing, automotive, and cutting tool sectors, metallic thin film coatings are crucial due to their tribological and protective properties. This research focuses on the development of metallic thin films of Aluminum (Al), Chromium (Cr) and Titanium (Ti) using deposition techniques like Sputtering and Electron Beam Evaporation. Metallic thin films were fabricated, with variations in thickness for each material, allowing for an in-depth study of the effects of Sputtering and Ebeam Evaporation deposition method on film characteristics. The thickness of these metallic thin films were evaluated using High-Resolution Scanning Electron Microscopy (HRSEM) and Profilometer while …


Analytical Electrochemistry Of Nickel, Platinum, And Platinum-Nickel Electrodepositions, Kyle James Troche Mar 2025

Analytical Electrochemistry Of Nickel, Platinum, And Platinum-Nickel Electrodepositions, Kyle James Troche

Nanoscience and Microsystems ETDs

Nickel and platinum electrodeposits have numerous applications in corrosion and wear-resistant coatings, electronic connectors, heat resistance, metal finishings, and catalysts. The addition of additives can vastly change the morphology of the deposition. Electrokinetic parameters can be calculated by conducting rotating disk electrode (RDE) experiments along with Koutecky-Levich analysis. Significant challenges need to be addressed to deposit uniform films of Pt-Ni alloys from a single co-deposition bath. The main challenge is platinum’s catalytic property to reduce the overpotential for the hydrogen generation reaction. An Investigation into methanol and carbon monoxide’s hydrogen generation reaction suppression was conducted. Electrodeposition of nickel, platinum, and …


Cost-Effective Active Laser Scanning System For Depth-Aware Deep-Learning-Based Instance Segmentation In Poultry Processing, Pouya Sohrabipour, Chaitanya Kumar Reddy Pallerla, Amirreza Davar, Siavash Mahmoudi, Philip Crandall, Wan Shou, Yu She, Dongyi Wang Mar 2025

Cost-Effective Active Laser Scanning System For Depth-Aware Deep-Learning-Based Instance Segmentation In Poultry Processing, Pouya Sohrabipour, Chaitanya Kumar Reddy Pallerla, Amirreza Davar, Siavash Mahmoudi, Philip Crandall, Wan Shou, Yu She, Dongyi Wang

School of Industrial Engineering Faculty Publications

The poultry industry plays a pivotal role in global agriculture, with poultry serving as a major source of protein and contributing significantly to economic growth. However, the sector faces challenges associated with labor-intensive tasks that are repetitive and physically demanding. Automation has emerged as a critical solution to enhance operational efficiency and improve working conditions. Specifically, robotic manipulation and handling of objects is becoming ubiquitous in factories. However, challenges exist to precisely identify and guide a robot to handle a pile of objects with similar textures and colors. This paper focuses on the development of a vision system for a …


A Comparison Of Unconventional Microwave And Ultrasound-Assisted Extraction Methods Used For Flavonoids, Istiqomah Rahmawati, Daffa Hafiziaulhaq Azizi, Jihan Nafila Wibowo, Muhammad Reza, Boy Arief Fachri, Bekti Palupi, Meta Fitri Rizkiana, Helda Wika Amini, Ifan Ramadana, Felix Arie Setiawan Mar 2025

A Comparison Of Unconventional Microwave And Ultrasound-Assisted Extraction Methods Used For Flavonoids, Istiqomah Rahmawati, Daffa Hafiziaulhaq Azizi, Jihan Nafila Wibowo, Muhammad Reza, Boy Arief Fachri, Bekti Palupi, Meta Fitri Rizkiana, Helda Wika Amini, Ifan Ramadana, Felix Arie Setiawan

Makara Journal of Science

Cocoa pods (Theobroma cacao L.) are a rich source of flavonoids, which are natural antioxidants known for their health benefits. This study investigated the use of microwave-assisted extraction (MAE) and ultrasound-assisted ex-traction (UAE) to extract the maximum flavonoids and antioxidants from cocoa pods. MAE and UAE are efficient and sustainable methods for extracting bioactive compounds like flavonoids and antioxidants from cocoa pods, offer-ing faster extraction, reduced solvent use, and better compound preservation compared to conventional methods. These technologies unlock the untapped potential of cocoa pods for applications in food, cosmetics, and pharmaceuti-cals. The effects of extraction time (2–10 min), microwave …


Flipping Out: Role Of Arginine In Hydrophobic Interactions And Biological Formulation Design, Jonathan W.P. Zajac, Praveen Muralikrishnan, Idris Tohidian, Xianci Zeng, Caryn L. Heldt, Sarah L. Perry, Et. Al. Mar 2025

Flipping Out: Role Of Arginine In Hydrophobic Interactions And Biological Formulation Design, Jonathan W.P. Zajac, Praveen Muralikrishnan, Idris Tohidian, Xianci Zeng, Caryn L. Heldt, Sarah L. Perry, Et. Al.

Michigan Tech Publications

Arginine has been a mainstay in biological formulation development for decades. To date, the way arginine modulates protein stability has been widely studied and debated. Here, we employed a hydrophobic polymer to decouple hydrophobic effects from other interactions relevant to protein folding. While existing hypotheses for the effects of arginine can generally be categorized as either direct or indirect, our results indicate that direct and indirect mechanisms of arginine co-exist and oppose each other. At low concentrations, arginine was observed to stabilize hydrophobic polymer folding via a sidechain-dominated direct mechanism, while at high concentrations, arginine stabilized polymer folding via a …


Solid Wastes From Geothermal Energy Production And Implications For Direct Lithium Extraction, William T. Stringfellow, Mary K. Camarillo Mar 2025

Solid Wastes From Geothermal Energy Production And Implications For Direct Lithium Extraction, William T. Stringfellow, Mary K. Camarillo

Pacific Faculty Work

Direct lithium extraction (DLE) of brines after geothermal power production offers opportunities to produce environmentally benign “green” lithium; however, some environmental impact is inevitable. We examined solid waste production at geothermal power plants in southern California that are also locations for planned DLE facilities. Currently, the geothermal plants in this region produce approximately 79,800 metric tons (wet weight) per year of solid waste, which represents about 28 metric tons per GWh of net electricity production or approximately 500 mg solids per kg geothermal brine. Approximately 15% of this waste requires management as hazardous waste. Solids produced during power production represent …


Efficiency Of Enzyme Induced Carbonate Precipitation (Eicp) By Crude Extract Urease For Geotechnical And Geoenvironmental Applications, Kaniz Roksana Mar 2025

Efficiency Of Enzyme Induced Carbonate Precipitation (Eicp) By Crude Extract Urease For Geotechnical And Geoenvironmental Applications, Kaniz Roksana

Theses and Dissertations

Geotechnical engineering is currently facing challenges, including accommodating rapid urbanization, adapting to climate change impacts, and prioritizing sustainability, all while ensuring the safety and stability of critical infrastructure. Biocementation is a recently developed new branch in geotechnical engineering that offers innovative and eco-friendly solutions by leveraging natural processes to enhance soil properties. This dissertation examines the potential of soybean extract urease as a cost-effective substitute for analytical-grade enzymes in Enzyme Induced Carbonate Precipitation (EICP) applications for biocementation. This research examines its effectiveness in various aspects, such as coastal erosion control, desiccation crack remediation, and the removal of heavy metals. Essential …


Emg-Based Intraoperative Neuromonitoring Using Advanced Machine Learning Approaches, Abdalla Nabil Elsharkawy, Nourhan Zayed Mar 2025

Emg-Based Intraoperative Neuromonitoring Using Advanced Machine Learning Approaches, Abdalla Nabil Elsharkawy, Nourhan Zayed

Mechanical Engineering

Intraoperative neuromonitoring (IONM) plays a critical role in minimizing nerve damage during surgeries by providing real-time feedback on neural integrity. This study evaluated models associated with deep learning and machine learning models for electromyography classification of signal during intraoperative neuromonitoring (IONM). The CNNLSTM model achieved the highest accuracy (85.2%), outperforming traditional models like KNN (53%), RF (62%), and CNN (76%). This demonstrates the degree to which the CNN-LSTM model can gain insight into temporal and spatial dependencies throughout the EMG signals, which makes it optimal for real-time classification in IONM applications. This implies that deep learning techniques can improve surgical …


Neurophisology Biosignals Of Cognitive Training Classification In Virtual Reality Environment Using Deep Learning Model, Nourhan Zayed, Mohamed Reda Mar 2025

Neurophisology Biosignals Of Cognitive Training Classification In Virtual Reality Environment Using Deep Learning Model, Nourhan Zayed, Mohamed Reda

Mechanical Engineering

This research investigates the potential of neurophysiological biosignals fusion, such as electroencephalogram (EEG) and Eye Tracking signals (ET), to classify cognitive states during virtual reality (VR) training, specifically for the rehabilitation of neurodegenerative diseases. By analyzing EEG data collected from participants engaged in VR-based cognitive exercises, we aim to identify patterns associated with different cognitive states and develop a robust classification system. A Convolutional Neural Network (CNN) model was developed to predict task performance utilizing neurophysiological inputs in an immersive world. This system could be used to monitor cognitive function, assess treatment efficacy, and provide real-time feedback to adapt the …


Effect Of Temperature On Physicochemical Properties Of Plasticized Hydroxypropyl Methylcellulose K100–Carbopol 934 Films Containing Propylene Glycol As Plasticizer, Braja Bihari Panda, Rudra Narayan Sahoo, Amit Kumar Nayak Mar 2025

Effect Of Temperature On Physicochemical Properties Of Plasticized Hydroxypropyl Methylcellulose K100–Carbopol 934 Films Containing Propylene Glycol As Plasticizer, Braja Bihari Panda, Rudra Narayan Sahoo, Amit Kumar Nayak

Makara Journal of Science

This paper studies the effect of different temperatures on different important physicochemical characteristics of plasti-cized hydroxypropyl methylcellulose (HPMC) K100-Carbopol 934 films containing propylene glycol (as a plasticizer), such as the rheology, thickness, folding endurance, tensile strength, elongation, and in vitro swelling with diffusion ki-netics. Rheology of HPMC K100-Carbopol 934 blend dispersions containing propylene glycol (before film casting) demonstrates that the flow is shear thinning and pseudoplastic. In the study of in vitro swelling, the relaxation-controlled transport is the predominant process of solvent diffusion into these plasticized HPMC K100–Carbopol 934 blend films under study. The results suggest that the solvent transport …


Chitosan Extraction From Anabas Testudineus Scales For Enhancing The Properties Of Edible Corn Starch-Based Films: Characterization And Performance Evaluation, Yuli Ristianingsih, Ivan Aldino Hernadin, Daniel Timotius Mar 2025

Chitosan Extraction From Anabas Testudineus Scales For Enhancing The Properties Of Edible Corn Starch-Based Films: Characterization And Performance Evaluation, Yuli Ristianingsih, Ivan Aldino Hernadin, Daniel Timotius

Makara Journal of Science

The papuyu fish (Anabas testudineus) is a freshwater species found in South and Southeast Asia. It is known for its ability to survive in extreme conditions, such as low oxygen levels and poor water quality, making it a potential candi-date for climate-resilient aquaculture. In this study, chitosan was extracted from the scales of papuyu fish through de-mineralization using 1 N HCl solution, deproteination using 5% NaOH solution, and deacetylation using 70% NaOH solution, resulting in an overall yield of 5.11%. The extracted chitosan was added to edible film made from corn starch, and the properties of the prepared films were …


Federated Learning-Driven Iot And Edge Cloud Networks For Smart Wheelchair Systems In Assistive Robotics, Mazin Abed Mohammed, Mohd Khanapi Abd Ghani, Abdullah Lakhan, Bourair Al-Attar, Waleed Khaled Mar 2025

Federated Learning-Driven Iot And Edge Cloud Networks For Smart Wheelchair Systems In Assistive Robotics, Mazin Abed Mohammed, Mohd Khanapi Abd Ghani, Abdullah Lakhan, Bourair Al-Attar, Waleed Khaled

Iraqi Journal for Computer Science and Mathematics

These days, assistive robotics and their applications for people with disabilities have become a revolutionary field in medical care. It combines edge-cutting technologies such as the Internet of Things (IoT), edge computing networks, and federated learning, offering the best services to disabled people for mobility and navigation in the environment. However, in the state of the art, many conceptual models are presented, and less effort is put into the practical implementation of assistive robots for disabled people in the environment. With this motivation, we propose an intelligent assistive robotics wheelchair system that enhances disabled care in federated learning-enabled IoT and …


Fabrication Of Docetaxel Loaded Pcl/Plga Electrospun Nanofibers For Lung Cancer Therapy, Rahul Tiwari, Fnu Pranav, Eswara N. Hanuma Kumar Ghali, Subhash Chauhan, Murali Yallapu, Luis Chavez Mar 2025

Fabrication Of Docetaxel Loaded Pcl/Plga Electrospun Nanofibers For Lung Cancer Therapy, Rahul Tiwari, Fnu Pranav, Eswara N. Hanuma Kumar Ghali, Subhash Chauhan, Murali Yallapu, Luis Chavez

Research Symposium

Background: Electrospinning is a commonly employed method in tissue engineering due to its ability to produce nano-/microscale fibrous materials with mechanical and functional properties that mimic the extracellular matrix of living tissues. The general interest in electrospun fibrous matrices has recently expanded to cancer research both as scaffolds for in vitro cancer modeling and as patches for in vivo therapeutic delivery. This research aims to investigate the efficient delivery of anticancer drug in lung cancer treatment.

Methods: Three different biocompatible polymeric nanofibers (i.e. PCL fibers, PCL-PLGA mixed fibers, and PCL-PLGA tetra-layered fibers) loaded with docetaxel, were prepared using electrospinning technique. …


The Interplay Between Endothelial Glycocalyx Maturity And Both The Toxicity And Intracellular Uptake Of Charged Nanoparticles, Claire A. Bridges, Lu D. Fu, Jonathan A. Yeow, Xiaojing D. Huang, Miriam D. Jackson, Rhiannon P. Kuchel, James D. Sterling, Shenda M. Baker, Megan S. Lord Mar 2025

The Interplay Between Endothelial Glycocalyx Maturity And Both The Toxicity And Intracellular Uptake Of Charged Nanoparticles, Claire A. Bridges, Lu D. Fu, Jonathan A. Yeow, Xiaojing D. Huang, Miriam D. Jackson, Rhiannon P. Kuchel, James D. Sterling, Shenda M. Baker, Megan S. Lord

Business and Information Technology Faculty Research & Creative Works

Nanoparticles are widely studied for delivering treatments to target tissues, but few have reached clinical use. Most nanoparticles encounter blood vessels on their way to target tissues. The inner surface of these vessels is lined with endothelial cells covered by a glycocalyx, an extracellular matrix rich in anionic glycans. The role of the glycocalyx in nanoparticle interactions is not well understood. Here, we demonstrate that endothelial cells need extended culture times to synthesize a mature glycocalyx. Our research shows that branched polyethyleneimine functionalized gold nanoparticles bind to endothelial cells expressing either a developing or mature glycocalyx, with the interaction involving …


Enhancing Mucus Flow And Clearance By Grafting Zwitterionic Hydrogel Films To Luminal Surfaces, Ryan Horne, Caleb Escudero, Morgan Ellerman, C. Allan Guymon, Marlan Hansen Mar 2025

Enhancing Mucus Flow And Clearance By Grafting Zwitterionic Hydrogel Films To Luminal Surfaces, Ryan Horne, Caleb Escudero, Morgan Ellerman, C. Allan Guymon, Marlan Hansen

Faculty Publications

Objective

To determine the effects of zwitterionic hydrogel films on mucus contact angles, flow, and stasis with respect to medical polymer surfaces, both flat and tubular.

Methods

A zwitterionic hydrogel thin film was photografted onto medical rubber surfaces and compared against non-zwitterionic hydrogel thin films and untreated surfaces to determine its impact on mucus contact angles, mucus flow on sheets and tubes, and mucus plugging.

Results

Zwitterionic and conventional hydrogel films significantly reduce the mucus contact angles and the tilt required to initiate mucus flow on sheets and in tubular systems. Preliminary experiments show that these films may also shorten …


Dynamic Spectral And Systems-Theoretic Approaches For Inference And Control Of Heterogeneous Complex Networks, Bharat Kumar Singhal Mar 2025

Dynamic Spectral And Systems-Theoretic Approaches For Inference And Control Of Heterogeneous Complex Networks, Bharat Kumar Singhal

McKelvey School of Engineering Graduate Student Theses & Dissertations

Networks of nonlinear systems are commonly employed to describe a diverse range of phenomena across physics, engineering, neuroscience, and biology. The undesirable behaviors of such systems, in the form of neurological disorders, power grid failures, or ecological collapses, have spurred significant interest in understanding their dynamic structures and developing effective control strategies. These systems are typically large-scale, consist of heterogeneous units, and are partially observable with limited measurement data, presenting theoretical and computational challenges for control design and connectivity inference. This thesis addresses these challenges by developing novel algorithms for pattern formation in populations of stable limit-cycle oscillators and connectivity …


Dynamic Spectral And Systems-Theoretic Approaches For Inference And Control Of Heterogeneous Complex Networks, Bharat Kumar Singhal Mar 2025

Dynamic Spectral And Systems-Theoretic Approaches For Inference And Control Of Heterogeneous Complex Networks, Bharat Kumar Singhal

McKelvey School of Engineering Graduate Student Theses & Dissertations

Networks of nonlinear systems are commonly employed to describe a diverse range of phenomena across physics, engineering, neuroscience, and biology. The undesirable behaviors of such systems, in the form of neurological disorders, power grid failures, or ecological collapses, have spurred significant interest in understanding their dynamic structures and developing effective control strategies. These systems are typically large-scale, consist of heterogeneous units, and are partially observable with limited measurement data, presenting theoretical and computational challenges for control design and connectivity inference. This thesis addresses these challenges by developing novel algorithms for pattern formation in populations of stable limit-cycle oscillators and connectivity …


Coastal Environments: Lidar Mapping Of Copper Tailings Impacts, Particle Retention Of Copper, Leaching, And Toxicity, W. Charles Kerfoot, Gary Swain, Robert Regis, Varsha K. Raman, Colin N. Brooks, Chris Cook, Et. Al. Mar 2025

Coastal Environments: Lidar Mapping Of Copper Tailings Impacts, Particle Retention Of Copper, Leaching, And Toxicity, W. Charles Kerfoot, Gary Swain, Robert Regis, Varsha K. Raman, Colin N. Brooks, Chris Cook, Et. Al.

Michigan Tech Publications

Tailings generated by mining account for the largest world-wide waste from industrial activities. As an element, copper is relatively uncommon, with low concentrations in sediments and waters, yet is very elevated around mining operations. On the Keweenaw Peninsula of Michigan, USA, jutting out into Lake Superior, 140 mines extracted native copper from the Portage Lake Volcanic Series, part of an intercontinental rift system. Between 1901 and 1932, two mills at Gay (Mohawk, Wolverine) sluiced 22.7 million metric tonnes (MMT) of copper-rich tailings (stamp sands) into Grand (Big) Traverse Bay. About 10 MMT formed a beach that has migrated 7 km …


Mg And Fe Co-Doped Perovskites For The Electrochemical Oxidative Coupling Of Methane In Solid Oxide Electrolyzers, Luke H. Denoyer Mar 2025

Mg And Fe Co-Doped Perovskites For The Electrochemical Oxidative Coupling Of Methane In Solid Oxide Electrolyzers, Luke H. Denoyer

Chemical and Biological Engineering ETDs

More efficient usage of shale gas reserves and natural gas resources will allow for higher olefin yields and lower greenhouse gas emissions. The oxidative coupling of methane (OCM) is a direct pathway for converting methane to ethylene at temperatures >700 °C. The OCM process is typically regulated via the choice of catalyst, reactor conditions, temperature range and gas mixing. The electrochemical oxidative coupling of methane (E-OCM) is a modification to the OCM reaction by controlling the oxygen content via externally applied potentials to an SOEC. Perovskite oxide catalysts are useful for E-OCM due to their flexible bond networks and desired …


Nanomaterials For Hydrogen Energy: Advancing Sustainable Fuel Solutions, Ganesan Kadirgama Mar 2025

Nanomaterials For Hydrogen Energy: Advancing Sustainable Fuel Solutions, Ganesan Kadirgama

The Nexus of Sustainability and Energy Technology Journal

Hydrogen energy is recognized as a cornerstone for future clean energy systems. Nanomaterials play a critical role in advancing hydrogen production, storage, and utilization by offering unique properties such as high surface area, enhanced catalytic activity, and superior stability. This paper explores the application of nanomaterials in hydrogen energy systems, focusing on their contributions to sustainability and efficiency. The challenges and prospects of integrating nanomaterials into hydrogen technologies are also discussed.