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Full-Text Articles in Entire DC Network
Hydrothermal Alteration Mapping Of The Northern Coongan Greenstone Belt Using Remote Sensing Imagery, Meaza Bogale, Elias Woldeyohanis
Hydrothermal Alteration Mapping Of The Northern Coongan Greenstone Belt Using Remote Sensing Imagery, Meaza Bogale, Elias Woldeyohanis
Journal of Sustainable Mining
Archean greenstone belts are well known for their ore deposits, diverse lithostratigraphy, and well-preserved evidence from the early Earth. The Northern Coongan Greenstone Belt is an Archean greenstone belt that is part of the Eastern Pilbara Craton of Western Australia. The rock units of this area have the potential to be sources of valuable mineral deposits, which could be economically beneficial for extraction. Studies have been conducted in the northern Coongan greenstone belt, mostly using geological field methods and geophysical interpretations, excluding remote sensing methods for mapping mineral indices. Therefore, this study aims at providing surface mineral distribution maps and …
Bitseat: Reimagining The Financing For Airliners Using Nonfungible Tokens (Blockchain Technology), Edwin S. Ongola
Bitseat: Reimagining The Financing For Airliners Using Nonfungible Tokens (Blockchain Technology), Edwin S. Ongola
Journal of Aviation Technology and Engineering
This essay describes how blockchain technology, particularly nonfungible tokens, can be used to raise funding for airliners. The essay begins with a brief overview on the costs, categories, and acquisition methods of airliners. After that, the essay introduces concepts on blockchain technology, tokens, and smart contracts. The essay then touches on how nonfungible tokens can be used to facilitate fractional ownership of airliners. From there, the essay discusses Bitseat, a conceptual nonfungible token for fractional ownership of airliners, covering its overall design, appeal, marketplace alternatives, and challenges. Finally, in the discussion, the essay summarizes the overall concept and outlines its …
Saas As The Backbone Of Digital Transformation: How Ai Turned Cloud Software Into Intelligent Enterprise Infrastructure, Amar Fejzić
Communications of the IIMA
Software-as-a-Service (SaaS) has become one of the most consequential infrastructures of digital transformation because it lowers the cost, time, and complexity of adopting enterprise capabilities. At the same time, artificial intelligence (AI), especially generative and conversational AI, is changing SaaS from a delivery model into an intelligent operating layer that automates workflows, personalizes customer interactions, and supports data-driven decisions. This paper develops a conceptual synthesis of academic literature and public organizational cases to examine how SaaS shaped digital transformation and how AI is reshaping SaaS itself. The analysis shows that SaaS enables scalable experimentation, faster deployment, and modular integration, while …
Aerodynamic Effects Optimisation Of Water-Powered Funicular Car Body Exposed To Headwind And Crosswind, Theodorus Agung Wicaksono, Bagus Wahyudi, Syamsul Hadi, Wirawan Wirawan, Hangga Wicaksono
Aerodynamic Effects Optimisation Of Water-Powered Funicular Car Body Exposed To Headwind And Crosswind, Theodorus Agung Wicaksono, Bagus Wahyudi, Syamsul Hadi, Wirawan Wirawan, Hangga Wicaksono
Journal of Mechanical Engineering Science and Technology (JMEST)
Water-powered funicular railways are an environmentally friendly mode of transport whose efficiency heavily depends on the principle of gravity. However, their operation is vulnerable to natural wind disturbances that can hinder speed or cause a risk of overturning on steep, curved tracks. This study aims to analyse the influence of funicular car model design on the rolling moment exerted on the rails as the car turns to enter a track branch. The research methodology involves aerodynamic simulations using SolidWorks flow simulation, comparing three body models: WAHYUDI, FUNAERO, and AEROFUN. Simulations were conducted with variations in turn angles (10° to 30°) …
The Evolution Characteristics Of Gas Pressure Around Coal Seam Directional Long Extraction Boreholes With Nonlinear Extraction Negative Pressure, Zhang Qi, Jia Jinlong, Li Zhiguo, Zhang Longgang, Qin Zhengyuan, Zhang Weizhong, Li Jin
The Evolution Characteristics Of Gas Pressure Around Coal Seam Directional Long Extraction Boreholes With Nonlinear Extraction Negative Pressure, Zhang Qi, Jia Jinlong, Li Zhiguo, Zhang Longgang, Qin Zhengyuan, Zhang Weizhong, Li Jin
Journal of Sustainable Mining
Nonlinear pressure of coal seam gas in the directional borehole and surrounding areas affects extraction efficiency. A multi-field coupling numerical model, including gas desorption, diffusion, fracture seepage, and borehole extraction, is developed for the No. 3 coal seam of the GJH mine. Using the numerical simulation method of control variables, extraction was developed to investigate the nonlinear evolution of axial pressure gradients in directional long borehole and the spatiotemporal response characteristics of gas pressure. Results show that coal seam seepage pressure exhibits a nonlinear radial gradient attenuation around the borehole, evolving through rapid pressure change, stabilization, and slow adjustment. The …
Calibration And Performance Of Germanium High Voltage Detectors For Supercdms Snolab, M. F. Albakry, I. Alkhatib, D. Alonso-González, J. Anczarski, T. Aralis, T. Aramaki, A. Ashtari Esfahani, I. Ataee Langroudy, R. Bhattacharyya, A. J. Biffl, P. L. Brink, M. Buchanan, R. Bunker, B. Cabrera, R. Calkins, R. A. Cameron, P. Camus, C. Cartaro, D. G. Cerdeño, Y. Y. Chang, M. Chaudhuri, J. H. Chen, R. Chen, J. Cooley, J. Corbett, P. Cushman, R. Cyna, S. Das
Calibration And Performance Of Germanium High Voltage Detectors For Supercdms Snolab, M. F. Albakry, I. Alkhatib, D. Alonso-González, J. Anczarski, T. Aralis, T. Aramaki, A. Ashtari Esfahani, I. Ataee Langroudy, R. Bhattacharyya, A. J. Biffl, P. L. Brink, M. Buchanan, R. Bunker, B. Cabrera, R. Calkins, R. A. Cameron, P. Camus, C. Cartaro, D. G. Cerdeño, Y. Y. Chang, M. Chaudhuri, J. H. Chen, R. Chen, J. Cooley, J. Corbett, P. Cushman, R. Cyna, S. Das
All Works
As SuperCDMS SNOLAB is getting ready to search for low mass dark matter particles, using cryogenic Ge and Si detectors, a set of six of the new SuperCDMS High Voltage (HV) detectors (four Ge and two Si) were tested in the Cryogenic Underground TEst facility (CUTE) at SNOLAB. This provided the first opportunity to gain experience with this new detector type and assess their performance thoroughly under low background conditions. Here we describe the SuperCDMS HV detector concept and discuss some of the newly developed analysis methods and approaches. Focusing on the Ge detectors, we investigate the detector performance under …
Understanding Mental Wellness In Collegiate Pilots: The Interplay Of Fatigue, Sleep, And Health-Promoting Behaviors, Flavio Antonio Coimbra Mendonca, Samantha Bowyer, Carolina Anderson, Bill Deng Pan
Understanding Mental Wellness In Collegiate Pilots: The Interplay Of Fatigue, Sleep, And Health-Promoting Behaviors, Flavio Antonio Coimbra Mendonca, Samantha Bowyer, Carolina Anderson, Bill Deng Pan
Journal of Aviation Technology and Engineering
This study investigates patterns of fatigue severity, sleep hygiene, daytime sleepiness, and health-promoting lifestyle behaviors and examine the interrelationships among these factors in collegiate aviation students. Participants included undergraduate professional pilot students enrolled in a Code of Federal Regulations Part 141 four-year aviation degree program in the southeastern United States (N = 82).
Participants completed four validated self-report instruments: the Fatigue Severity Scale, the Sleep Hygiene Index, the Epworth Sleepiness Scale, and the Health-Promoting Lifestyle Profile II. Descriptive analyses were conducted to characterize the results of each assessment, and Pearson correlations and multiple regression analyses were performed to examine intervariable …
Ai-Based Displacement Forecasting For Real-Time Landslide Risk Assessment In The Danube Region, Amina Čehaja, Asja Muharemović, Jasmin Kevrić, Dejan Jokić, Mirza Ponjavić
Ai-Based Displacement Forecasting For Real-Time Landslide Risk Assessment In The Danube Region, Amina Čehaja, Asja Muharemović, Jasmin Kevrić, Dejan Jokić, Mirza Ponjavić
Communications of the IIMA
This paper presents a dual-layered AI framework for real-time landslide risk assessment developed under the GeoNetSee project within the Interreg Danube Region Programme. The first layer employs a fuzzy logic model, inspired by the Slovenian MASPREM system, which integrates Landslide Susceptibility Maps (LSS) with high-resolution precipitation forecasts from the Open-Meteo API to generate a Predicted Landslide Hazard (PLSH) score on a 0–5 scale, updated every 6–12 hours. The second layer focuses on real-time ground displacement detection by fusing low-cost dual-frequency GNSS receivers with MEMS accelerometers and applying machine learning regression algorithms, including Support Vector Regression (SVR), Long Short-Term Memory (LSTM), …
From Disaster To Resilience: Developing Smart Settlements In The Himalayas, Keshav Bhattarai, Ambika P. Adhikari
From Disaster To Resilience: Developing Smart Settlements In The Himalayas, Keshav Bhattarai, Ambika P. Adhikari
Himalayan Research Papers Archive
Nepal’s catastrophic 26 August 2026 Bhote Koshi–Trishuli flood should be understood not only as a humanitarian tragedy but also as a potentially major turning point in updating national settlement and reconstruction policy. Engineers and scientists have described the floods as a glacier–bedrock collapse that triggered an ice-rock avalanche and debris flow. As per the live updates on September 7, 2026, the total death toll was 1,355, and 4,996 people were missing (The Hindu, 2026). Indian and Nepali rescuers worked urgently to locate and rescue people buried under hydropower tunnels, buildings, mud, and landslide debris.
UN News reported on September 3, …
Hyperlattice-Valued And Superhyperlattice-Valued Uncertain Sets With Decision Applications, Takaaki Fujita, Ajoy Kanti Das, Sankar Prasad Mondal, Arif Mehmood, Arkan Ghaib
Hyperlattice-Valued And Superhyperlattice-Valued Uncertain Sets With Decision Applications, Takaaki Fujita, Ajoy Kanti Das, Sankar Prasad Mondal, Arif Mehmood, Arkan Ghaib
Neutrosophic Systems with Applications
Fuzzy set theory enriches classical sets by assigning to each element a graded membership in [0,1], thereby capturing partial inclusion and uncertainty. The notion of an Uncertain Set further abstracts this idea by allowing membership to take values in a general degree-domain, providing a unified language that subsumes fuzzy, intuitionistic fuzzy, neutrosophic, plithogenic, and related models. On the algebraic side, a hyperlattice replaces one lattice operation by a multivalued hyperoperation, enabling the representation of ambiguous or non-deterministic combinations, while a superhyperlattice iterates this structure through powerset lifting to obtain higher-order layers of interaction. Motivated by these developments, we introduce HyperLattice-valued …
The Evolution Of Reliability Methods For Nondestructive Evaluation (Nde): From Probability Of Detection (Pod) Conception To Contemporary Practices, Christine E. Knott, Jennifer Brown, John Aldrin, Christine M. Schubert Kabban
The Evolution Of Reliability Methods For Nondestructive Evaluation (Nde): From Probability Of Detection (Pod) Conception To Contemporary Practices, Christine E. Knott, Jennifer Brown, John Aldrin, Christine M. Schubert Kabban
Faculty Publications
Nondestructive evaluation (NDE) methods are powerful tools for detecting and characterizing flaws in structural components, but their reliability must be evaluated before they can be used in critical applications. For more than 50 years, probabilistic and statistical methods have been used effectively to estimate reliability by describing an NDE system’s Probability of Detection (POD) for flaws of realistic sizes. The POD methods used by the USAF and NASA, like Hit/Miss, Signal-Response (â vs. a), and Point Estimate method (PEM, a.k.a. 29/29) have evolved, alongside newer approaches like Limited Sample POD (LS-POD) method, and Model Assisted Probability of Detection …
A Neutrosophic Event-Graph Legal Ai System For Detecting Contradictions In Witness Testimonies Under Egyptian Law, Shimaa Abdelghany Attalla, Alaa Elmor, Nada Hesham, Abduallah Gamal
A Neutrosophic Event-Graph Legal Ai System For Detecting Contradictions In Witness Testimonies Under Egyptian Law, Shimaa Abdelghany Attalla, Alaa Elmor, Nada Hesham, Abduallah Gamal
Neutrosophic Systems with Applications
Witness testimony is an important source of evidence in criminal proceedings, but it may contain contradictions, incomplete details, or conflicts with other case-file materials. This paper proposes a neutrosophic event-graph legal AI framework for detecting materially contested claims in witness testimonies under the Egyptian criminal-procedure context. The framework converts testimony and related records into structured claims containing actor, action, object, time, location, source, and modality. These claims are then connected through an event graph and evaluated using neutrosophic components of support, indeterminacy, and opposition. The system produces source-grounded legal-review alerts when a claim has sufficient opposition from other claims or …
An Interval-Valued Spherical Fuzzy Critic–Waspas Framework For Prioritizing Healthcare Delivery Models To Enhance Patient Satisfaction Under Uncertainty, Mariam Hamada, Ahmed Samy, Mohamed M. Abdelhafeez, Shrouk El-Amir
An Interval-Valued Spherical Fuzzy Critic–Waspas Framework For Prioritizing Healthcare Delivery Models To Enhance Patient Satisfaction Under Uncertainty, Mariam Hamada, Ahmed Samy, Mohamed M. Abdelhafeez, Shrouk El-Amir
Neutrosophic Systems with Applications
Selecting an appropriate healthcare delivery model is important for improving the quality of healthcare services and enhancing patient satisfaction. However, this decision is complex because it involves several criteria, uncertainty, and different expert opinions. To handle this uncertainty, this paper uses Interval-Valued Spherical Fuzzy Sets (IVSFSs), which allow experts to express their evaluations more flexibly. This paper proposes an integrated interval-valued spherical fuzzy CRITIC-WASPAS approach to prioritize healthcare delivery models. The CRITIC method is used to determine the objective weights of the evaluation criteria, while the WASPAS method is used to rank the healthcare delivery models. Expert evaluations are expressed …
20 Years Of Neutrosophic Statistics: A Bibliometric Analysis, Hammad Khalid, Arshad Hameed
20 Years Of Neutrosophic Statistics: A Bibliometric Analysis, Hammad Khalid, Arshad Hameed
Neutrosophic Systems with Applications
Florentin Smarandache introduced neutrosophic statistics (NS), a formalism for representing uncertainty and indeterminacy in observations, parameters and statistics in an extension to classical and interval statistics. Although widespread in various contexts, such as statistical quality control, hypothesis testing, medical diagnosis, and decision science, and increasingly used and developed, the scientific evolution and conceptual framework of the science of decision making remain largely unexamined. To fill this gap, the present study has been conducted with a comprehensive bibliometric analysis of NS research articles published between 2003 to 2025 from Scopus which has been conducted following the SPAR-4-SLR protocol. In all, 501 …
A Unified Framework For Neutrosophic Estimation Using Fractional Power, Exponential, And Logarithmic Functions With Bivariate Auxiliary Information, Anchal Yadav, Anuj Yadav
A Unified Framework For Neutrosophic Estimation Using Fractional Power, Exponential, And Logarithmic Functions With Bivariate Auxiliary Information, Anchal Yadav, Anuj Yadav
Neutrosophic Systems with Applications
This study develops a generalized neutrosophic ratio-type estimator for estimating the population mean by incorporating information from two auxiliary variables under Simple Random Sampling Without Replacement (SRSWOR). The proposed methodology extends the conventional single-auxiliary-variable approach by jointly incorporating bivariate auxiliary information within the neutrosophic framework, thereby accounting for uncertainty, indeterminacy, and inconsistency in the available information. The bias and mean squared error of the proposed estimator are derived using first-order approximations, and the corresponding efficiency conditions are established through theoretical comparisons with existing neutrosophic estimators. The performance of the proposed estimator is further examined using a real medical dataset represented …
Monitoring System In The Georeactor Area During The Underground Coal Gasification Process, Aleksandra Tokarz, Jacek Grabowski, Krzysztof Korczak
Monitoring System In The Georeactor Area During The Underground Coal Gasification Process, Aleksandra Tokarz, Jacek Grabowski, Krzysztof Korczak
Journal of Sustainable Mining
Safety control of the underground coal gasification (UCG) process involves ensuring that the process runs smoothly, monitoring changes occurring on the surface and in the rock mass, and counteracting the negative environmental impact of the process. The article presents the application of a monitoring system implemented in Poland, both in pilot tests conducted in shallow coal seams at the Barbara Experimental Mine and in deep coal seams at the Wieczorek mine, where a full-scale gasification process was tested. The analysis of the monitoring results carried out during the gasification experiment in an operating mine allowed for the identification of key …
From Himalayan Catastrophe To National Resilience: Lessons From The 2026 Bhote Koshi And Trishuli River Floods In Nepal, Keshav Bhattarai, Ambika P. Adhikari
From Himalayan Catastrophe To National Resilience: Lessons From The 2026 Bhote Koshi And Trishuli River Floods In Nepal, Keshav Bhattarai, Ambika P. Adhikari
Himalayan Research Papers Archive
On the morning of 26 August 2026, the mountains above Nepal’s northern frontier delivered a disaster of almost unimaginable speed and scale. A massive mass of ice, rock, and sediment detached in the high Himalayan terrain near the Nepal–Tibet border, descended roughly 1,200 metres, interacted with the Lhende Khola system, and generated a debris-rich flood that surged through the Bhote Koshi and Trishuli river corridors, destroying settlements, markets, roads, bridges, hydropower facilities, and an international border crossing and transforming them into fields of mud, boulders, and wreckage within minutes (ICIMOD, 2026b; Reuters, 2026a). Satellite analysis indicates that a substantial section …
Studying Electromagnetic Wave Scattering From Small Dielectric Particles Using Neural Networks, Bryan Taylan, Patrick Corzo, Chris Velissaris, Theodoros Panagiotakopoulos
Studying Electromagnetic Wave Scattering From Small Dielectric Particles Using Neural Networks, Bryan Taylan, Patrick Corzo, Chris Velissaris, Theodoros Panagiotakopoulos
Undergraduate Scholarship and Creative Works
Physics-informed neural networks solve the Helmholtz equation without labeled data, but a low residual alone does not confirm that a solution preserves the physical distinction a downstream task depends on. We trained a four-layer SIREN with physics-based residuals, a Sommerfeld condition, Adam, and L-BFGS, modeling a Gaussian source and a plane wave scattering from a small dielectric inclusion. Fine-tuning from four base models produced 600 complex fields spanning omega = 4 to 20. A compact CNN, three ResNet-18 variants, and a frozen OpenCLIP encoder classified these fields under five random seeds. The CNN achieved (95.65 +/- 0.77)% accuracy, outperforming OpenCLIP …
Harmonicthreads: A Formative Evaluation Of A Fabric-Based Digital Musical Instrument Toward Inclusive Music-Making, Ellie Nguyen, Franceli L. Cibrian
Harmonicthreads: A Formative Evaluation Of A Fabric-Based Digital Musical Instrument Toward Inclusive Music-Making, Ellie Nguyen, Franceli L. Cibrian
Engineering Faculty Articles and Research
Background:
Inclusive music-making requires instruments that support varied bodies, abilities, musical backgrounds, and forms of participation. Digital musical instruments provide diverse approaches to sound creation, and fabric-based interfaces offer an alternative interaction modality that may support participation for some users and contexts. Their tactile and deformable properties enable forms of interaction that differ from conventional rigid or screen-based controllers and may offer inclusive possibilities in particular settings.
Objective:
This paper presents HarmonicThreads as a formative interaction-design case of a fabric-based digital musical instrument. The prototype explores how tactile cues, fabric deformation, projected visual feedback, and assisted accompaniment can support low-barrier …
Phosphate Removal By Spent Low Temperature Shift Catalyst Through Process Optimization And Mechanistic Study, Fatma A. Hashem Eng., Abeer M. Shoaib Prof., Walaa Omar Dr., Mai H. Roushdy
Phosphate Removal By Spent Low Temperature Shift Catalyst Through Process Optimization And Mechanistic Study, Fatma A. Hashem Eng., Abeer M. Shoaib Prof., Walaa Omar Dr., Mai H. Roushdy
Chemical Engineering
Natural water bodies become eutrophic due to phosphate pollution from industrial and agricultural sectors. This research addresses waste disposal and water pollution at the same time by recycling spent low-temperature shift catalyst (LTSSC) from the fertilizer industry as a sustainable phosphate adsorbent. High surface area (247±5 m2/g), mesoporous structure, and many metal oxide sites (CuO 49%, ZnO 32.2%, and Al2O₃ 13.9%) were shown by characterization using XRF, XRD, BET, SEM–EDX, FTIR, particle size analysis, and zeta potential. Under optimum conditions (contact time 1.64 h, dose 5 g/L, initial concentration 9.58 mg/L, stirring 278 rpm), Response Surface Methodology optimization achieved 92.95±2.8% …
Artificial Intelligence In Food Engineering For Food Safety, Quality Assurance, And Human Health, Ayad Abbood Abdulhasan, A. M. Mustafa, F. F. Sayyid, Marwan B. Hussein, Mohanad Muzahem Khalaf
Artificial Intelligence In Food Engineering For Food Safety, Quality Assurance, And Human Health, Ayad Abbood Abdulhasan, A. M. Mustafa, F. F. Sayyid, Marwan B. Hussein, Mohanad Muzahem Khalaf
AUIQ Technical Engineering Science
Artificial intelligence (AI) is increasingly reshaping food engineering by providing data-driven tools for safeguarding food safety, ensuring quality assurance, and improving human health outcomes. This review synthesizes current evidence on the application of machine learning, deep learning, computer vision, and the Internet of Things (IoT) across the food production continuum, from raw material inspection to consumer-facing nutrition guidance. We examine how convolutional neural networks, hyperspectral imaging, and sensor-fusion approaches enable rapid, non-destructive detection of contaminants and pathogens, and how predictive models support shelf-life estimation and quality grading. We further discuss AI-enabled traceability systems, including blockchain-integrated supply chains, and the growing …
Edge Computing-Enabled Secure Federated Learning For Anomaly Detection In Industrial Iot Sensor Streams, Wijdan Noaman Marzoog Al Mukhtar
Edge Computing-Enabled Secure Federated Learning For Anomaly Detection In Industrial Iot Sensor Streams, Wijdan Noaman Marzoog Al Mukhtar
AUIQ Technical Engineering Science
The rise of the Industrial IoT (IIoT) will result in a surge of IIoT devices with high-velocity data streams requiring rapid, real-time analysis of these data streams to power predictive maintenance and assure cybersecurity. Centralized cloud-based approaches to anomaly detection are hindered by their inherent latency and privacy issues while independent or stand-alone approaches to edge-based anomaly detection do not have enough data to effectively detect anomalies. This paper presents a federated learning framework to collaboratively develop an anomaly detection model from multiple edge nodes, without sharing the raw sensor data, so that data sovereignty is preserved. Two major contributions …
Microwave Thermal Pre-Treatment To Improve Nickel Extraction From Lateritic Ore, Johana Borda, Daniel Sosa, Robinson Torres
Microwave Thermal Pre-Treatment To Improve Nickel Extraction From Lateritic Ore, Johana Borda, Daniel Sosa, Robinson Torres
Journal of Sustainable Mining
Two heat treatment processes for a nickeliferous laterite sample are presented, one by the conventional muffle route and the other by microwave. The heating was carried out in order to improve the dissolution of nickel in an acid medium. The study describes the changes observed in the mineral for the increase in temperature as a consequence of radiation in the microwave and in the muffle. The changes in the mineral crystalline phases were analyzed by X-ray diffraction. The leaching media consisted of a 1 M sulfuric acid solution at ambient conditions for 7 h. The interaction between the reagent and …
Ecofriendly Synthesis Of Silver Nanoparticles As Antimicrobial Active Agents From Its Cationic Precursors, Abdul Haris Watoni Watoni
Ecofriendly Synthesis Of Silver Nanoparticles As Antimicrobial Active Agents From Its Cationic Precursors, Abdul Haris Watoni Watoni
Chimica et Natura Acta
This review presents a comprehensive survey on the green synthesis of silver nanoparticles from silver nitrate precursor using plant extracts along with their characterization and antimicrobial activity assessment. The synthesis of silver nanoparticles through a green chemistry approach is increasingly in demand because it is environmentally friendly, easy to do, and efficient, especially for the purpose of antimicrobial active ingredients in disinfectant and antiseptic formulas. Green synthesis of silver nanoparticles can be carried out using silver nitrate as a silver precursor and plant extracts as a source of bioreductants and capping agents. The synthesis products are then characterized using UV-Vis …
Hydration-Tunable Ionic Liquid-In-Oil Microemulsions For Increased Transdermal Delivery Of High-Molecular-Weight Proteins, Roy Jabidash, Kiyohiro Toyofuku, Rie Wakabayashi, Yoshirou Kawaguchi, Noriho Jeffrey Kamiya, Muhammad Moniruzzaman, Masahiro Goto
Hydration-Tunable Ionic Liquid-In-Oil Microemulsions For Increased Transdermal Delivery Of High-Molecular-Weight Proteins, Roy Jabidash, Kiyohiro Toyofuku, Rie Wakabayashi, Yoshirou Kawaguchi, Noriho Jeffrey Kamiya, Muhammad Moniruzzaman, Masahiro Goto
Publications and Research
Transdermal delivery of high-molecular-weight proteins is challenging because of their large molecular size and hydrophilicity, and the barrier properties of the stratum corneum. We report a hydrated ionic liquid-in-oil (HIL/O) microemulsion for transdermal delivery of high-molecular-weight proteins. A biocompatible ionic liquid (IL) composed of cholinium cation and propionate anion, optimized at 45 wt% hydration, was developed as a protein-compatible solubilization medium that dissolved ovalbumin (molecular mass ∼ 45 kDa) and bovine serum albumin (molecular mass ∼ 66 kDa), whereas lower hydration levels were insufficient for effective protein dissolution. Following solubilization, circular dichroism spectroscopy showed recovery of the native-like secondary structures …
Death Of Battlefield Hide-And-Seek, Lily Cheatham
Death Of Battlefield Hide-And-Seek, Lily Cheatham
Space and Defense
For the past twenty years, the stealth regime defined military thinking, prioritizing technologies and tactics designed to evade enemy defense systems. Ensuring radar invisibility and maintaining information dominance have been the keys to survival and strategic advantage. On June 21-22, 2025, the United States conducted "Operation Midnight Hammer" against Iranian nuclear facilities at Fordow, Natanz, and Isfahan. The principal strike package included seven B-2 Spirit stealth bombers, whose crews flew approximately 18 hours to reach the target area and roughly 36 hours and 13,000 miles round trip. The B-2s dropped 14 GBU-57 Massive Ordnance Penetrators on Fordow and Natanz, marking …
A Cislunar Economic Forecast Under Public-Private Partnership, Naisha Chirag Naik
A Cislunar Economic Forecast Under Public-Private Partnership, Naisha Chirag Naik
Space and Defense
Cislunar space, spanning Earth’s orbit to the Moon, has emerged as a new frontier due to its strategic, scientific, and economic potential, with growing involvement from global powers, governments, and private entities diversifying the market. Unlike the first lunar space race, which saw a spike in activity amongst two countries followed by “silence,” the current cislunar era is hallmarked by a growing mix of public agencies, private companies, and international actors seeking to gain a foothold in what could be the foundation for a long-term space economy. While cislunar space was historically only an interest for superpowers, recent years have …
Autonomous Navigation In Cislunar Satellites, Heith Johnson
Autonomous Navigation In Cislunar Satellites, Heith Johnson
Space and Defense
Cislunar space—the region between Earth’s geosynchronous orbit (about 36,000 kilometers from Earth) and the Moon (roughly 384,000 kilometers away)—is becoming a critical frontier for future space exploration and commercialization.1 This zone includes the Moon’s orbit, transfer orbits, and the Earth-Moon Lagrange points. Additionally, as more nations and corporations launch lunar missions and establish long-term infrastructure, cislunar space is increasingly becoming a strategic focus for exploration, logistics, and transportation.
Planetary Defense As The Ethico-Legal Gateway For International Space Security, Evie Kendal
Planetary Defense As The Ethico-Legal Gateway For International Space Security, Evie Kendal
Space and Defense
Following the news in late 2024 that there was a city-killer asteroid on a possible collision course with Earth, many members of the public were shocked to learn there was no reliable global plan for managing such asteroidal and cometary impact hazards. While calculations of Asteroid 2024 YR4’s trajectory were further refined to exclude the previously reported 2-3% chance of collision in 2032, this event highlighted a major security threat: the lack of a globally coordinated, appropriately resourced, and politically supported planetary defense strategy (Gibney, 2025). In so doing, it also provided an opportunity for security experts to consider the …
Space-Based Missile Defense With Early Interceptor Launch Strategies, William Priedhorsky, James Wells
Space-Based Missile Defense With Early Interceptor Launch Strategies, William Priedhorsky, James Wells
Space and Defense
There is renewed interest in space-based boost-phase intercept (SBPI) for missile defense against ICBMs of near-peer adversaries. We discuss SBPI in the context of other missile defense approaches, and address one of its challenges, which is the expense of fielding a large enough constellation of interceptors in space to counter even a small number of ICBMs. We develop an early-launch approach that could substantively reduce the required density of interceptors. Because every second matters in boost-phase defense, early launch of interceptors can significantly increase the reach of each interceptor. Early launch would require interceptors that have highly throttleable motors. Our …