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Alkaline Hydrogen Peroxide Pretreatment For Its Use In An On-Farm Bioprocessing Facility, Mary Kathryn Gray

Theses and Dissertations--Biosystems and Agricultural Engineering

Pretreatment is an essential step in biofuel production from lignocellulose. Disruption of the lignin structure gives enzymes and fermentation organisms access to long chains of cellulose and hemicellulose. For this project’s purposes, the pretreatment must work within the framework of an on-farm butanol bioprocessing facility. Alkaline hydrogen peroxide (AHP) is a delignification method that potentially provides several advantages. At the alkaline pH, powerful hydroxyl radicals are formed; which attack lignin. The objectives of this study were to determine if AHP removes substantial lignin for the feedstocks, corn stover, wheat straw, switchgrass and miscanthus, and to determine if AHP acts as …

Nutrients Recycling Strategy For Microalgae-Based Co2 Mitigation System, Xinyi E

Theses and Dissertations--Biosystems and Agricultural Engineering

Coal-fired electricity production is the major emitter of CO₂ and other greenhouse gases including NO_x and SO_x. Microalgae-based CO₂ mitigation systems have been proposed to reduce the net CO₂ emission from coal-fired power plants. This study focused on developing an optimum culture media and exploring the possibilities for recycling nutrients, which were added as commercial mineralized chemicals at the beginning of cultivation.

In order to release the nutrients embedded in the cells so that they can be used as a nutrient source for new cells, Scenedesmus biomass was digested by anaerobic bacteria. Results showed …

Molecular Dynamics Simulation Studies Of Interaction Of Amphiphilic Molecules With Lipid Bilayers, Jieqiong Lin

LSU Doctoral Dissertations

We use molecular dynamics simulations to investigate the behavior of various amphiphilic molecules in aqueous solutions in the presence of vitamin E or lipid bilayers. Our research studies focus on two molecular systems. First, we investigate the effect of DMSO on structural properties of DMPC bilayers and calculate bilayers permeability coefficients for both water and DMSO molecules at low DMSO concentration. The simulations show that the increase of DMSO concentration in solution leads to an increase of the permeability of water through the bilayers. The permeability increase might explain the unusual ability of DMSO, even at relatively low concentrations, to …

Engineering Novel Terpene Production Platforms In The Yeast Saccharomyces Cerevisiae, Xun Zhuang

Theses and Dissertations--Plant and Soil Sciences

The chemical diversity and biological activities of terpene and terpenoids have served in the development of new flavors, fragrances, medicines and pesticides. While terpenes are made predominantly by plants and microbes in small amounts and as components of complex mixtures, chemical synthesis of terpenes remains technically challenging, costly and inefficient. In this dissertation, methods to create new yeast lines possessing a dispensable mevalonate biosynthetic pathway wherein carbon flux can be diverted to build any chemical class of terpene product are described. The ability of this line to generate diterpenes was next investigated. Using a 5.5 L fed bath fermentation system, …

Evaluating The E-Consult Process For Diabetes Care Delivery At An Outpatient Care Clinic, Brian M. Zoll

Browse all Theses and Dissertations

The occurrence of one of the most common chronic conditions in the U.S., diabetes, is expected to rise 53% from 24 million cases in 2003 to 37 million cases in 2023. The U.S. Veterans Health Administration (VHA) is not immune to this. The VHA has experienced an $820 million increase spending on diabetes patients between 2000 and 2008. The VHA has tried to keep the growth of chronic care costs in check through improvements in patient access to care by expanding its network of community-based outpatient clinics. Other methods the VHA has used to curb chronic care spending costs are …

Bacillus Thuringiensis: Transgenic Crops, Julie A. Peterson, John J. Obrycki, James D. Harwood

Department of Entomology: Faculty Publications

Bacillus thuringiensis (Bt) crops, genetically modified to express insecticidal toxins that target key pests of corn, cotton, rice, potato, and other crops, have been rapidly adopted and have become dominant fixtures in agroecosystems throughout the world. Due to the constitutive nature of Bt toxin expression, insecticidal proteins may be found in nearly all plant tissues, presenting multiple sources for Bt toxins to enter the environment, thus creating complex direct and indirect pathways for non-target organisms to be exposed to insecticidal proteins. The environmental impacts of Bt crops have been widely debated, although both benefits and risks do exist. Benefits of …

Evaluation Of Endogenous Allergens For The Safety Evaluation Of Genetically Engineered Food Crops: Review Of Potential Risks, Test Methods, Examples And Relevance, Richard E. Goodman, Rakhi Panda, Harsha Ariyarathna

Department of Food Science and Technology: Faculty Publications

The safety of food produced from genetically engineered (GE) crops is assessed for potential risks of food allergy on the basis of an international consensus guideline outlined by the Codex Alimentarius Commission (2003). The assessment focuses on evaluation of the potential allergenicity of the newly expressed protein(s) as the primary potential risk using a process that markedly limits risks to allergic consumers. However, Codex also recommended evaluating a second concern, potential increases in endogenous allergens of commonly allergenic food crops that might occur due to insertion of the gene. Unfortunately, potential risks and natural variation of endogenous allergens in non-GE …

Acetyl-Coa Carboxylases Are Checkpoints In Adipocyte Differentiation, Elizabeth Lyn Cordonier, Daniel Camara Teixeira, Zhonghi Han, Angela K. Pannier, Janos Zempleni

Department of Agricultural and Biological Systems Engineering: Faculty Publications

No abstract provided.

Bile-Acid-Mediated Decrease In Endoplasmic Reticulum Stress: A Potential Contributor To The Metabolic Benefits Of Ileal Interposition Surgery In Ucd-T2dm Rats, Bethany P. Cummings, Ahmed Bettaieb, James L. Graham, Jaehyoung Kim, Fangrui Ma, Noreene Shibata, Kimber L. Stanhope, Cecilia Giulivi, Frederik Hansen, Jacob Jelsing, Niels Vrang, Mark Kowala, Michael L. Chouinard, Fawaz G. Haj, Peter J. Havel

Nebraska Center for Biotechnology: Faculty and Staff Publications

Post-operative increases in circulating bile acids have been suggested to contribute to the metabolic benefits of bariatric surgery; however, their mechanistic contributions remain undefined. We have previously reported that ileal interposition (IT) surgery delays the onset of type 2 diabetes in UCD-T2DM rats and increases circulating bile acids, independently of effects on energy intake or body weight. Therefore, we investigated potential mechanisms by which post-operative increases in circulating bile acids improve glucose homeostasis after IT surgery. IT, sham or no surgery was performed on 2-month-old weight-matched male UCD-T2DM rats. Animals underwent an oral fat tolerance test (OFTT) and serial oral …

Biomechanical Comparison Of Lower Limb Unloading Between Common Modalities Of Ankle Foot Orthoses, Andrea Blake Wanamaker

Electronic Theses and Dissertations

Tibial stress fractures and other lower extremity injuries can be treated using an ankle foot orthosis (AFO). AFOs are popular because they allow the patient to ambulate somewhat naturally while reducing weight bearing on the injured limb. Despite their popularity, it is currently unclear how well AFOs reduce lower extremity weight bearing.

The first objective of this investigation was to examine the ability of three commonly used ankle foot orthoses to reduce weight bearing within the lower limb by comparing the ground reaction force measured from a force platform to the force measured from an insole pressure measurement device inside …

Sustainable Energy Production In The United States: Life Cycle Assessment Of Biofuels And Bioenergy, Jiqing Fan

Dissertations, Master's Theses and Master's Reports - Open

The United States of America is making great efforts to transform the renewable and abundant biomass resources into cost-competitive, high-performance biofuels, bioproducts, and biopower. This is the key to increase domestic production of transportation fuels and renewable energy, and reduce greenhouse gas and other pollutant emissions.

This dissertation focuses specifically on assessing the life cycle environmental impacts of biofuels and bioenergy produced from renewable feedstocks, such as lignocellulosic biomass, renewable oils and fats. The first part of the dissertation presents the life cycle greenhouse gas (GHG) emissions and energy demands of renewable diesel (RD) and hydroprocessed jet fuels (HRJ). The …

Computational Prediction Of The Sporulation Network In Clostridium Thermocellum, Changyi Jiang

Dissertations, Master's Theses and Master's Reports - Open

Sporulation is a process in which some bacteria divide asymmetrically to form tough protective endospores, which help them to survive in a hazardous environment for a quite long time. The factors which can trigger this process are diverse. Heat, radiation, chemicals and lacking of nutrition can all lead to the formation of endospores. This phenomenon will lead to low productivity during industrial production. However, the sporulation mechanism in a spore-forming bacterium, Clostridium theromcellum, is still unclear. Therefore, if a regulation network of sporulation can be built, we may figure out ways to inhibit this process. In this study, a …

Cancer Risk Analysis By Fuzzy Logic Approach And Performance Status Of The Model, Atinç Yilmaz, Kürşat Ayan

Turkish Journal of Electrical Engineering and Computer Sciences

Cancer is the leading life-threatening disease for people in today's world. Although cancer formation is different for each type of cancer, it has been determined by studies and research that stress also triggers cancer types. Early precaution is very important for people who have not fallen ill yet with a disease like cancer that has a high mortality rate and expensive treatment. With this study, we expound that the possibility of developing such disease may be decreased and people could take measures against it. For the 3 cancer types selected as pilot work by introducing a fuzzy logic model, the …

Printable Biodegradable Hydrogel For Skin Wound Dressing Using Inkjet Printing Technology, Maria G. Yanez

Open Access Theses & Dissertations

Chronic wounds are becoming more frequent. Foot ulcers affect approximately 10% - 15% of patients with diabetes throughout their lifetimes, and by 2025, it is estimated the prevalence of diabetes will be 250 million people in the worldwide. There is increased potential for patients with peripheral neuropathy and peripheral vascular disease to suffer more foot injuries. These conditions reduce the normal pain sensations and healing of minor traumas, allowing the development of chronic non-healing ulcers, often preceding lower-extremity amputation. These types of wounds are very difficult to treat and sometimes take months or even years to heal because of many …

Safety And Efficacy Of Ranolazine For The Treatment Of Chronic Angina Pectoris, Mohammed Aldakkak, David F. Stowe, Amadou K.S. Camara

Biomedical Engineering Faculty Research and Publications

Coronary heart disease is a global malady and it is the leading cause of death in the United States. Chronic stable angina is the most common manifestation of coronary heart disease and it results from the imbalance between myocardial oxygen supply and demand due to reduction in coronary blood flow. Therefore, in addition to lifestyle changes, commonly used pharmaceutical treatments for angina (nitrates, ß-blockers, Ca2+ channel blockers) are aimed at increasing blood flow or decreasing O2 demand. However, patients may continue to experience symptoms of angina. Ranolazine is a relatively new drug with anti-anginal and anti-arrhythmic effects. Its anti-anginal mechanism …

Linking Obesity To Colorectal Cancer: Recent Insights Into Plausible Biological Mechanisms, Catherine Guffey

Theses and Dissertations

Obesity has emerged as a leading environmental risk factor for the development of CRC. However, the mechanisms underlying this relationship have not yet been fully explained. Recent literature has focused on 1) inflammatory processes, 2) adipokines, and 3) estrogen. Obesity-enhanced inflammation is largely orchestrated by increases in adipose tissue macrophages leading to the secretion of TNF-alpha, MCP-1, and IL-6, all of which are linked to CRC. Adiponectin is decreased with obesity and has been reported to be negatively associated with CRC, while leptin, which is increased, is positively associated with the disease. Estrogen has been shown to influence CRC, although …

Modeling Ultrasonic Field Emanating From Scanning Acoustic Microscope For Reliable Characterization Of Pathogens (Biological Materials), Rowshan Ara Rima

Theses and Dissertations

Acoustic microscopy provides extraordinary advantages over state-of-the-art invasive imaging techniques to determine the mechanical properties of living colonies of pathogens and micro-organisms. It is possible to obtain the morphomechanical parameters of the pathogenic colonies e.g. variation of thickness, stiffness and the coefficients of attenuation, using scanning acoustic microscope (SAM). However, the process requires an expert with extensive understanding of SAM and ultrasonic signals which is very time consuming and expensive for complex form of analysis. Due to lack of a suitable computational tool, presently the ultrasonic wave scattering, reflection and transmission through the biological specimens cannot be properly visualized. Without …

Characterizing Hypoxia And Its Behavioral Effects In 3-Dimensional Cell Aggregates, Matthew Lorincz Skiles

Theses and Dissertations

Cell transplantation can be considered a regenerative therapy, an intervention which attempts to replace or restore the function of compromised tissue by harnessing innate properties of cells that cannot be replicated artificially. For such therapies to succeed, it will be necessary to understand and closely match the physiological conditions that govern cell behaviors in vivo. One important factor is low oxygen tension, termed hypoxia, which is often overlooked in vitro. Because oxygen insufficiency can lead to cell death, hypoxia has traditionally been viewed as a negative condition. However, hypoxia can also serve as a potent regulator of crucial cell behaviors …

Assessing Appropriate Technology Handwashing Stations In Mali, West Africa, Colleen Claire Naughton

USF Tampa Graduate Theses and Dissertations

Proper hand hygiene is the most effective and efficient method to prevent over 1.3 million deaths annually from diarrheal disease and Acute Respiratory Infections (ARIs). Hand hygiene is also indispensable in achieving the fourth Millennium Development Goal (MDG) to reduce the childhood mortality rate by 2/3rds between 1990 and 2015. Handwashing has been found in a systematic review of studies to reduce diarrhea by 47%#37; and is, thus, capable of preventing a million deaths (Curtis et. al., 2003). Despite this evidence, hand washing rates remain seriously low in the developing world (Scott et al., 2008).

This study developed and implemented …

Bio-Inspired Design, Fabrication And Testing Of Bipolar Plates For Pem Fuel Cells, Nannan Guo

Doctoral Dissertations

"The flow field of a bipolar plate distributes reactants for polymer electrolyte membrane (PEM) fuel cells and removes the produced water from the fuel cells. It greatly influences the performance of fuel cells, especially the concentration losses. Two approaches were developed to improve flow field designs in this dissertation. One is inspired by the biological circulatory structures and called bio-inspired designs, which have great potential to transport reactant efficiently and hence improve fuel cell performance. Another way is using a network-based optimization model to optimize the conventional flow field configurations, i.e., pin-type, parallel and serpentine designs, to improve flow distributions …

Investigation Of Best Practices For Maintenance Of Concrete Bridge Railings, Angel Luis Lence

LSU Master's Theses

Biodeterioration on concrete surfaces of vertical elements of bridges represents a serious challenge to the highway infrastructure in Louisiana. This investigation aims to document the causes of biodeterioration of concrete surfaces and to document current conventional and state-of-the-art practices implemented to prevent and clean biofilm. A comprehensive literature review of previous research has been carried out in order to determine the cause and mechanisms of the biodeterioration as well as to identify current methods that state DOTs have implemented in order to maintain their bridges and allow them to function in optimal structural and performance conditions. A survey was developed …

Engineering Of Hydroponic Systems To Enhance Biomass Of Sea Oats (Uniola Paniculata), Stefanie Renee Gilliam

LSU Master's Theses

Restoration projects use native plants such as sea oats (Uniola paniculata) to help stabilize the coast. Sea oats are a native grass that can collect blowing sand to build dunes. Sea oats used in the restoration projects can be produced using sexual or asexual techniques. An ideal seedling would be genetically distinct, have increased seed production and germination, and have superior vegetative biomass. Finding ways to produce, propagate, and grow coastal plants such as sea oats effectively is critical to efforts to reduce erosion. In this study, production of sea oats via greenhouse based hydroponic systems was studied. This was …

Effect Of Microwave Heating On The Migration Of Additives From Ps, Pp And Pet Container Into Food Simulants, Ruoyin Cai

Theses

Microwave food packaging has become a tremendous element in the food manufacturing process. The purpose of any food packaging regulations concerned with the safety of the food is to control and limit the migration of substances from the packaging into the food. The main objective of this thesis is to test three different microwaving packaging materials that are the most common material in the market, viz. polystyrene (PS), polypropylene (PP), and polyethylene terephthalate (PET), migrated into four food simulant solutions. Four different simulant solutions were used based on the food type and FDA recommendations and regulations. These food simulants include …

Long-Term Integrated Studies Show Complex And Surprising Effects Of Climate Change In The Northern Hardwood Forest, Peter M. Groffman, Charles T. Driscoll, Chris E. Johnson, Lindsey E. Rustad, Pamela H. Templer

Civil and Environmental Engineering - All Scholarship

Evaluations of the local effects of global change are often confounded by the interactions of natural and anthropogenic factors that overshadow the effects of climate changes on ecosystems. Long-term watershed and natural elevation gradient studies at the Hubbard Brook Experimental Forest and in the surrounding region show surprising results demonstrating the effects of climate change on hydrologic variables (e.g., evapotranspiration, streamflow, soil moisture); the importance of changes in phenology on water, carbon, and nitrogen fluxes during critical seasonal transition periods; winter climate change effects on plant and animal community composition and ecosystem services; and the effects of anthropogenic disturbances and …

Creating Tomorrow, Fall 2012, College Of Engineering

College of Engineering Magazines

Annual magazine for the College of Engineering at Utah State University.

Product Display Versus Graphical Representation On Packaging, Joshua Galvarino

All Theses

ABSTRACT
Previous research conducted (Hurley, et al., 2012) concerning physical and graphical product visibility from the primary display panel (PDP) is limited to one product category. This research expands previous peer-reviewed research, which indicates that there is a significant difference between consumer preferences of graphical display vs. physical product display on packaging.
The shelf presence of packages showing actual product visibility versus packages showing only a graphical representation of the product was evaluated. Both shopping results and quantitative data using eye-tracking technology were collected and cross-referenced with a qualitative, post-experiment survey.
Specifically, variables of packaging within pasta, snacks, prepared frozen …

Avataraudiometer: An Online Simulation Platform For Pure-Tone Audiometry, Daniel Weidman, Lauren Calandruccio

Intersections Fall 2020

Simulation education for medical and health professional training bridges classroom learning and training in a clinical environment. Its use has been increasing over the past two decades. Guidance to avoid in-person contact due to SARS-CoV-2 has further increased demand. Pure-tone audiometry is part of an audiometric test battery used to evaluate the auditory system. At Case Western Reserve University, students typically learn to conduct audiometry in COSI 370: Introduction to Audiology. Under current pandemic circumstances, students are unable to gain in-person experience using standard hardware (an audiometer and calibrated headphones). AvatarAudiometer solves this problem via an interactive online tool that …

Md Mouse: Integrated Blood Pressure Device, Anand Shah, Jamila Mckenzie, Rex Weinstein, Noelle Nelson, Clayton Goertemiller

Intersections Fall 2020

Hypertension, or high blood pressure, is a public health concern due to both its pervasiveness and the significant risk of disability, stroke, or heart attack that can occur years after high blood pressure is detected. Furthermore, new pandemic statistics suggest that patients with hypertension experience greater health consequences of COVID-19, indicating that the condition is more circumstantially deadly. Occasional visits to a doctor's office, the most common method to measure blood pressure, only provide a snapshot of a person's blood pressure and are not an accurate characterization. This is because blood pressure can fluctuate based on daily changes to the …

Morphometric, Biochemical, And Raman Spctral Analyses Of Muscle Damage In Patients With Peripheral Arterial Disease: Provising Objective Criteria For Diagnosis And Treatment Monitoring, Kim Cluff

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Peripheral arterial disease (PAD), which affects approximately 10 million Americans, is characterized by atherosclerosis of the non-coronary arteries. PAD produces a progressive accumulation of ischemic injury to the limbs that is reflected in a gradual worsening in the myofiber morphology and oxidative damage in the gastrocnemius muscle. In this study, we evaluated the hypothesis that quantitative morphological and biochemical parameters of gastrocnemius myofibers change in a consistent manner during the progression of PAD, provide an objective grading of muscle degeneration in the ischemic limb, and correlate to clinical stage of PAD. Myofiber morphometrics were determined precisely with mathematical equations that …

Using The Greet Model To Analyze Algae As A Feedstock For Biodiesel Production, Christopher Tatum

Masters Theses and Doctoral Dissertations

There is a growing interest in renewable, carbon-neutral biofuels such as ethanol and biodiesel. A life-cycle analysis is conducted in this study to determine the viability of using algae as a feedstock for biodiesel. The method involves assessing energy use, fossil fuel use, greenhouse gas emissions, and criteria pollutant emissions using a simulation developed by Argonne National Laboratory. The energy and emissions of algae-derived biodiesel are compared to those of soybean biodiesel, corn ethanol, conventional gasoline, and low-sulfur diesel. Results show that there are sizeable greenhouse gas emission benefits attributed to the production of both types of biodiesel as compared …