Digital Commons Network^™

Detection Of Unauthorized Transmissions In A Frequency Spectrum Using Wireless Sensor Network, Joel Brinkman, Jannette Gonzalez, Benjamin Roehrig, Dylan Zupec

Honors Capstones

A prototype for a wireless sensor network has been designed to detect and identify unauthorized wireless transmissions in a frequency spectrum. This prototype design is intended to detect unauthorized transmissions within the FM band of frequencies independently at individual nodes with Software Defined Radio receivers and transmit that information to a fusion center for aggregation using a Bluetooth mesh network. Aggregated results will be displayed to the user through a Graphical User Interface at the fusion center.

Thematic Synthesis: Rethinking Generative Music With Compositional Understanding In Game And Software Development, Jasper Moore Tucker

Dartmouth College Master’s Theses

Generative music, first introduced by composers like Brian Eno and David Cope in the mid-to-late 20th century, has evolved through many stages, with diverse applications across music and technology companies as well as the game industry. However, despite this widespread interest, there remains a notable lack of the foundational understanding of composition and individual expressiveness in current generative systems that was apparent in the work of early composers. This paper advocates for a shift towards prioritizing compositional thought in system design to foster greater diversity and innovation within generative music. To demonstrate this approach, a novel system synthesizing two distinct …

Identification Of Compounds That Cause Axonal Dieback Without Cytotoxicity In Dorsal Root Ganglia Explants And Intervertebral Disc Cells With Potential To Treat Pain Via Denervation, Fei San Lee, Uyen N. Nguyen, Eliza J. Munns, Rebecca A. Wachs

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Low back pain, knee osteoarthritis, and cancer patients suffer from chronic pain. Aberrant nerve growth into intervertebral disc, knee, and tumors, are common pathologies that lead to these chronic pain conditions. Axonal dieback induced by capsaicin (Caps) denervation has been FDA-approved to treat painful neuropathies and knee osteoarthritis but with shortterm efficacy and discomfort. Herein, we propose to evaluate pyridoxine (Pyr), vincristine sulfate (Vcr) and ionomycin (Imy) as axonal dieback compounds for denervation with potential to alleviate pain. Previous literature suggests Pyr, Vcr, and Imy can cause undesired axonal degeneration, but no previous work has evaluated axonal dieback and cytotoxicity …

Creating A Bio-Based Circular Economy From Louisiana Sugarcane Byproducts, G. Aita, D. Bhatnagar, G. O. Bruni, M. Deliberto, G. Eggleston, A. Finger, K. Gravois, M. Isied, W. Judice, K. T. Kasson, I. M. Lima, J. L. Purswell, Mena I. Souliman, E. Terrell, B. S. Tubana, H. L. Waguespack Jr., J. J. Wang, P. M. White Jr.

Civil Engineering Faculty Publications and Presentations

Sugarcane (Saccharum officinarum) is Louisiana's number one row crop. Growing and processing sugarcane produces significant amounts of byproducts, including bagasse, crop residue, molasses, filter-press mud, and boiler fly ash. These products represent an important opportunity to generate value-added and specialty products and enhance sugarcane's sustainability by facilitating a circular economy, where agricultural by-products are reused instead of disposing them (linear economy), in order to reduce resource use and energy demand. Examples of value-added products range from biochar, construction materials, animal feed, biofuels, nanoparticles, and fertilizer. Paramount to the success of the bio-based circular economy is creating useful products that are …

Evaluating Tissue Morphology In The Context Of Varied Initial Fabrication Conditions, Cassidy Caffin

Biomedical Engineering Undergraduate Honors Theses

Cardiovascular diseases have been the leading cause of death for years. This includes myocardial infarctions (MI) where blood flow to the myocardium is restricted. This causes damage to cardiac muscle due to insufficient oxygen. There are multiple ways to treat patients following an MI with the most common involving assorted medication. However, there are limited medications that can be used for treating patients following MIs, and the FDA’s decreasing approval rate for new cardiac drugs will not dramatically improve the range of options. The lead-up to drug candidate rejection by the FDA can involve drugs exhibiting promising preliminary research that …

Enhancing Cybersecurity In Wireless Sensor Networks: Machine Learning, Blockchain And Future Perspectives, Ilemona Solomon Atawodi

Dissertations

Security in the Industrial Internet of Things encounters various security issues but the main issues can be broken down into three core issues: Availability, Integrity, and Confidentiality. Security challenges generally tend to be caused by a failure of the system in one of these areas or cause a failure in one of these areas. Therefore researching scalable solutions to these security issues is prudent to explore methods that could be applied to large-scale industrial IIoT with tens to hundreds of devices as well as small-scale systems on a tiny factory floor comprising of just a few devices. In our research, …

Data-Driven And Cell-Specific Determination Of Nuclei-Associated Actin Structure, Nina Nikitina, Nurbanu Bursa, Matthew Goelzer, Madison Goldfeldt, Chase Crandall, Sean Howard, Janet Rubin, Anamaria Zavala, Aykut Satici, Gunes Uzer

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Quantitative volumetric assessment of filamentous actin (F-actin) fibers remains challenging due to their interconnected nature, leading researchers to utilize threshold-based or qualitative measurement methods with poor reproducibility. Herein, a novel machine learning-based methodology is introduced for accurate quantification and reconstruction of nuclei-associated F-actin. Utilizing a convolutional neural network (CNN), actin filaments and nuclei from 3D confocal microscopy images are segmented and then each fiber is reconstructed by connecting intersecting contours on cross-sectional slices. This allows measurement of the total number of actin filaments and individual actin filament length and volume in a reproducible fashion. Focusing on the role of F-actin …

Addressing Data Limitations Of Commercial Waterways Via Machine Learning And Stochastic Optimization, Sanjeev Bhurtyal

Graduate Theses and Dissertations

Freight transportation is a crucial component of the US economy, with truck, rail, and water contributing significantly to the Gross Domestic Product (GDP). However, challenges arise in maintaining infrastructure capacity to accommodate the growing tonnage and value of freight transportation. Waterways offer high efficiency and environmental friendliness, with the capacity to transport substantial cargo volumes. Utilizing waterways can alleviate bottlenecks in landside transportation, accommodating the rising tonnage of commodity flow in the US. Despite the advantages of waterway transportation, the data limitations hinder informed decision-making regarding port operation and infrastructure investment. The lack of granularity and timeliness in available data …

Investigating The Presence Of Patented In Vitro Models For Cancer-Nerve Crosstalk Methods, Christoff Hauptmann

Biomedical Engineering Undergraduate Honors Theses

The purpose of this research project is to investigate the presence of patented in vitro models for perineural invasion (PNI) and tumor innervation, the two most prominent modes of cancer-nerve crosstalk that play an active role in cancer initiation and progression. PNI occurs through a positive feedback loop in which cancer cells invade passive nerves to metastasize. Tumor innervation is the process where tumor cells attract nearby nerves to the tumor microenvironment (TME) for tumor growth and metastasis. These crosstalk paths have been established for many types of cancer and result in poor patient prognosis. Recently, in vitro models have …

Evaluation Of The Efficiency Of Muscle-Specific Promoters To Express Non-Endogenous Proteins In Skeletal Muscle, Gabrielle Bulliard, Made Harumi Padmaswari, Christopher E. Nelson

Biomedical Engineering Undergraduate Honors Theses

Gene therapies are emerging as powerful tools for treating genetic diseases and cancers, offering the potential for a permanent cure. Hemophilia B, affecting approximately 6,000 men in the U.S., results from a deficiency in coagulation factor IX protein (FIX), which is crucial for blood clotting. A substantial portion of patients, over 40%, suffer from severe hemophilia B, experiencing spontaneous, prolonged bleeding. Current prophylactic treatments involve frequent coagulation factor infusions, yet a curative approach would alleviate this burden. Gene editing technologies like CRISPR-Cas systems show promise for correcting genetic mutations, but the diverse nature of factor IX gene (F9) …

Safety Analysis In Ap-1000 Nuclear Power Plant Against Primary Loop Coolant Pump And Fuel Failures, Fabiano Gibson Daud Thulu, Hailemichael Guadie Mengsitu, Chifundo Tenthani, Paul Stone Macheso

International Journal of Nuclear Security

This study focused on the best-estimated thermal-hydraulic calculations performed regarding the AP-1000 nuclear power plant (NPP) under primary coolant loop pump and fuel failures. Primary coolant pump and fuel failure transients are important design-basis accidents in NPP safety assessments. This work examined the primary reactor’s safety margins of fuel and cladding peak temperature, primary and secondary loop pressure, hydrogen formation, and primary and secondary flow rates.The Adaptive System Thermal-Hydraulics program was used in the simulation and event progression analysis. The results showed that the peak fuel surface temperature was kept below the licensing design limit. No observation of corium was …

Does California High-Speed Rail Promote Accessibility For Station Cities?: Case Study Of Fresno And Merced, Chih-Hao Wang, Na Chen

Mineta Transportation Institute

California High-Speed Rail (CHSR) will largely change transportation cost across the state after it starts operating. Past studies show that only Fresno and Merced among station cities in the Central Valley would attract more future activities with the CHSR. The establishment of active CHSR also implies a new daily living sphere for all the station cities, and, therefore, accessibility to work and residential amenities should be reviewed to inform planners of future land-use and transportation developments. A research framework has been developed better to understand the impact of CHSR on job and amenity accessibility by driving, transit, and walking in …

Open-Source Optimization For Green Last Mile Delivery And Other Applications, John Sooter

Industrial Engineering Undergraduate Honors Theses

Solving combinatorial optimization problems at scale and of sufficiently interesting context has historically required commercial solvers and access to proprietary company data. The development of performant open-source mathematical programming software and crowdsourced datasets has created an opportunity for individuals and enterprises alike to consider alternative solutions to problems with social and personal implications. This honors thesis represents a summary of my undergraduate research work, an application of optimization to three distinct problems connected to these developments. First, we present an optimization study of a last mile delivery system that shows optimization for energy consumption can generate vehicleindependent fuel savings at …

Investigating Rural Traffic Dynamics: A Traffic Study On E 2nd Street Intersection’S Behavior And Safety, Ma Anjelika Rose T. Pineda

2024 Spring Honors Capstone Projects - Archive

Traffic studies guide engineers in designing road networks to ensure smooth traffic flow and public safety. Such studies assess the need for traffic control devices to manage vehicle flow safely and efficiently. This is crucial at intersections which pose high risks of collision and congestion. A traffic analysis at the intersection of Island Grove and E 2nd Street on the FM-4 roadway in Cleburne, TX was conducted to evaluate the sufficiency of the current traffic control device. TxDOT warrants and standards and a field study were utilized and performed to justify the substitution for a traffic signal at the intersection. …

An Assessment Of Methane Cracking Technologies For Hydrogen Production And Reduction Of Greenhouse Gases, Alisa E. Pjetrovic

2024 Spring Honors Capstone Projects - Archive

Methane reformation and methane pyrolysis involve separating, or cracking, the components of methane, leading to the production of hydrogen gas, and in the case of pyrolysis, solid carbon. Because methane is known as a leading cause of climate change, these technologies are gaining attention as the global community moves to address methane as a greenhouse gas. This study aims to assess, through a systematic literature review, the current state-of-the-art methane cracking technologies based on seven technology criteria: hydrogen production capability, environmental impact, value of carbon produced, reaction stability, operating temperature requirements, energy requirements, and Technology Readiness Level (TRL). This study …

What Is Biological Engineering? – A Magazine, Morgan Christensen

Undergraduate Honors Capstone Projects

Biological Engineering is one of the less commonly known fields of engineering and can be challenging to describe to someone outside the discipline. The most common question I've been asked during my undergraduate career is "What is biological engineering?". My answer has changed throughout my time at Utah State University as I've had more experiences within the discipline. This project focuses on answering this question in the format of a magazine to help bridge the gap between those in the discipline and a general audience. By using a magazine as the format, the content must be organized and written in …

Testing Resilience Of Microalgae Biofilms When Exposed To Hydrothermal Liquefaction Aqueous Phase, Davis Riley Haag

Undergraduate Honors Capstone Projects

There are a multitude of experimental and processing techniques in the bioenergy field that produce sustainable and carbon negative to carbon neutral methods of converting renewable resources into biologically based hydrocarbons. One example of a process is hydrothermal liquefaction (HTL) which specializes in converting wet biomass into biocrude oil. One reason that these processes are not used outside experimental testing is due to the high cost of performing these processes. There is potential to move these processes to larger scale testing and eventually industrial adaptation if breakthroughs are made to offset the process expenses. There is a waste product produced …

Acoustofluidic Delivery Of Biomolecules To Cells: A Novel Approach For Preparing Car-T Cells., Madison C. Colebank

Electronic Theses and Dissertations

The continuous pursuit of effective methods for gene transfection in primary human T cells is crucial for advancing cell-based therapies. Viral vectors, currently used in cell-based therapies, involve a lengthy and costly process. This thesis explores the efficacy of coupling acoustofluidic and sonoporation techniques as an alternative non-viral gene transfection approach with primary T cells. Sonoporation, in conjunction with microbubbles, has been demonstrated to induce cavitation, resulting in the formation of pores in the cell membrane through which molecules can enter. Using flow cytometry, we compared the loading efficiency of primary T cells with that of Jurkat T cells to …

A Comprehensive Materials Approach To Thermal Management In Fiber Lasers, Bailey Meehan

All Dissertations

Optical fiber-based amplifiers and lasers enable a great many useful devices and conveniences. Unfortunately, however, they can generate considerable heat during operation that drives the need for complex cooling solutions, thus reducing many of the size, weight, and power (SWAP) benefits for which fiber lasers are known. Additionally, at elevated temperatures, thermally-driven phenomena, such as Transverse Mode Instability (TMI), can be induced that limit the power-scaling of fiber lasers. The focus of this Dissertation is to explore novel approaches to thermal management in fiber lasers through judicious materials science and engineering to obviate the aforementioned limitations. Fibers studied in this …

A Comprehensive Analysis Of Training Induced Heat-Related Injuries At Fort Moore, Anthony Beger

Data Science Undergraduate Honors Theses

Heat related injuries are a significant problem for the United States Armed Forces. There were over 11,000 confirmed cases of heat-related illnesses that were diagnosed at more than 230 military installations from 2018-2022. These injuries are primarily due to hyperthermia (i.e., abnormally high body temperature) resulting from extreme environmental temperatures, high humidity, medications, or excessive physical work or exercise. Fort Moore has the most heat related injuries of any installation in the U.S. Department of Defense since it is home to one of the largest U. S. Army training posts with most training involving intensive outdoor activity in high heat …

Primary Consolidation Settlement Of South Louisiana Clay Deposits In Marsh Environment, Alice E. Stark

LSU New Orleans Theses and Dissertations

Accurate estimation of primary consolidation of in-situ marsh soils is inherently difficult in south Louisiana due to the soft, settlement prone soils and variable alluvial material. To investigate the accuracy of settlement analysis methods commonly utilized in local practice, estimates from numerical models were compared to the results of a settlement monitoring program at a project site during construction. Sensitivity analyses were then performed using several parameters that were used in the settlement analysis, and the results were compared to the field observations.

The disagreement of observed settlement data and settlement estimates produced with a model that did not include …

Innovative Rate Design As A Free Market Solution To Climate, Resiliency, And Economic Challenges, Brendan J. Moore

LSU New Orleans Theses and Dissertations

A century-old problem of electricity rate design is cost-shifting between ratepayers (Wellinghoff, J. & Tong, J., 2015). A much newer cost-shifting example of great and increasing importance happens whenever ratepayer generated “renewable energy” is sold to the grid—all too often, this is accused of being unfairly rewarded (Ritchie, 2016). ProRate resolves both these concerns and ProRate can actually be derived simply from the premise of avoiding “all” cost shifts between ratepayers (Katz, CLEPm Rewards to Arrest Demand Cost-Shifting, 2019; Katz, CLEP5 Rewards to Arrest Energy Cost-Shifting, 2019). Another major problem with the Old Utility Model is the lack of price …

Optimization Of Collagen And Cell Concentrations For Engineered Tissues, Avery Fiser

Chemical Engineering Undergraduate Honors Theses

Improvements regarding the drug discovery process are necessary due to less than 1% of drugs making it from the initial discovery phase to patient treatment in clinics. One method of enhancing this process involves improving the relevance and dependability of in vitro testbeds utilized during pre-clinical testing. Improvement along these factors can provide a more relevant view for eventual drug behavior in patients. This additional relevance can allow for a reduced timeline in drug development for improving patient care. A consistent and morphologically sound baseline engineered tissue is vital to the creation of successful experimental models. Parameters such as cell …

Design And Fabrication Of Injectable Alginate Hydrogel Microstrands For Mesenchymal Stem Cell Delivery In Salivary Gland Tissue Regeneration, Sujith Chander Reddy Kollampally

Legacy Theses & Dissertations (2009 - 2024)

Fibrosis is a pathological wound healing process, driven by excessive accumulation of extracellular matrix (ECM) following tissue remodeling. Fibrosis occurs in diseased or damaged salivary glands caused by several conditions, such as Sjogren’s syndrome or radiation for head and neck cancers. Having better insight into the cellular and molecular progression of fibrosis will allow us to model new therapeutic approaches as fibrosis prevents salivary gland tissue regeneration and function. Pharmacological, tissue engineering and cell-based regeneration strategies have been widely explored to restore lost salivary gland function. Among cell-based therapies, exploitation of mesenchymal stromal/stem cells (MSC) for salivary gland regeneration has …

Unhsc Performance Curve And O&M Tracking Calculator, Daniel Macadam

UNH Stormwater Center

No abstract provided.

Quantifying The Role Of Karst Groundwater On Mountain River Discharge, Devon Hill

All Graduate Theses and Dissertations, Fall 2023 to Present

A primary objective of hydrological research is to anticipate the shifts in water supply due to climate change. These shifts are difficult to predict in karst areas like Logan Canyon because much of the water moves through large fractures and cave networks that transport groundwater quickly, but there are some groundwater fractions which move very slowly. Many studies in karst regions use spring dynamics to assess aquifer condition, but overlook other influences such as exchanges between a river and the underlying aquifer. In this study, we calculated the quantity and chemical makeup of these groundwater and surface water exchanges by …

Quantifying Image Quality In Aoslo Images Of Photoreceptors, Brea D. Brennan, Heather Heitkotter, Joseph Carroll, Sergey Tarima, Robert F. Cooper

Biomedical Engineering Faculty Research and Publications

The use of “quality” to describe the usefulness of an image is ubiquitous but is often subject to domain specific constraints. Despite its continued use as an imaging modality, adaptive optics scanning light ophthalmoscopy (AOSLO) lacks a dedicated metric for quantifying the quality of an image of photoreceptors. Here, we present an approach to evaluating image quality that extracts an estimate of the signal to noise ratio. We evaluated its performance in 528 images of photoreceptors from two AOSLOs, two modalities, and healthy or diseased retinas. The algorithm was compared to expert graders’ ratings of the images and previously published …

Evaluating Company Culture Of Roofing Contracting Companies To Attract And Retain Women In The Industry, Gopika Viswanathan

All Theses

The US construction industry, similar to many other industries, has a low representation of women. This difference is even more pronounced in construction trades, such as the roofing industry. The admission of more women into the industry is important to address workforce shortage issues that the industry is facing. Company culture has been cited as one of the primary reasons why women choose not to enter the industry or face barriers during their careers. The main objective of this study was to evaluate the company culture of roofing companies through factors identified by literature and by women and companies in …

Light-Induced Phase Separation Purification For Monoclonal Antibodies, Xuyang Chen

All Theses

none

Towing Tank Trials Of Hydrokinetic Turbine Scale Model To Support Marine Energy System Verification, Shahab Rouhi

LSU New Orleans Theses and Dissertations

In response to the escalating demand for sustainable energy solutions and the critical reevaluation of conventional fossil fuels due to environmental concerns, this dissertation embarks on a comprehensive exploration of hydrokinetic energy as a promising alternative. The study delves into the underexplored domain of hydrokinetic energy, leveraging innovative methodologies for effective utilization and harnessing, particularly through the development and investigation of hydrokinetic turbines.

In the realm of hydrokinetic energy conversion, our research has exclusively concentrated on horizontal-axis turbines, distinct from other turbine configurations. Noteworthy is the adaptation of a conventional horizontal-axis wind turbine for water currents, revealing enhanced performance through …