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The Santa Clara, 2024-05-28, Santa Clara University

The Santa Clara

No abstract provided.

Advancing Objective Mobile Device Use Measurement Inchildren Ages 6–11 Through Built-In Device Sensors: A Proof-Of-Concept Study, Olivia L. Finnegan, Robert Glenn Weaver Med, Phd, Hongpeng Yang, James W. White, Srihari Nelakuditi, Zifei Zhong, Rahul Ghosal Ph.D., Yan Tong, Aliye B. Cepni, Elizabeth L. Adams, Sarah Burkart Mph, Ph.D., Michael W. Beets Med, Mph, Phd, Bridget Armstrong Ph.D.

Faculty Publications

Mobile devices (e.g., tablets and smartphones) have been rapidly integrated into the lives of children and have impacted howchildren engage with digital media. The portability of these devices allows for sporadic, on-demand interaction, reducing theaccuracy of self-report estimates of mobile device use. Passive sensing applications objectively monitor time spent on a givendevice but are unable to identify who is using the device, a significant limitation in child screen time research. Behavioralbiometric authentication, using embedded mobile device sensors to continuously authenticate users, could be applied toaddress this limitation. This study examined the preliminary accuracy of machine learning models trained on iPad …

Digitally Beamformed 2d Scanning Phased Array Radar For Networked Unmanned Air Vehicle Detection And Tracking, Carson Reed Brown

Theses and Dissertations

Radar systems vary significantly in size, weight, power, and cost (SWaP-C) characteristics with many high SWaP-C models being inaccessible to consumers. Recognizing this, we have engineered an effective but low SWaP-C networked radar system tailored for detecting and tracking unmanned air vehicle (UAV) traffic. Using field-programmable gate arrays (FPGAs), and custom-designed printed circuit boards (PCBs), our system achieves remarkable efficiency without compromising performance. We use patch antennas for our transmitter and in our 4x4 receiver array. With our low SWaP-C system we have successfully concluded outdoor range testing, detecting corner reflector targets at a remarkable 10dB above our noise floor …

Nickel-Catalyzed Α-Arylation Of Α-Cyanoacetates Enabled By Electrochemistry, Zi-Meng Li, Zhang-Jian Li, Anat Milo, Ping Fang, Tian-Sheng Mei

Journal of Electrochemistry

β-Amino acids have a wide range of applications in the field of pharmaceuticals. Utilizing a combination strategy of nickel catalysis and paired electrolysis, a catalytic α-arylation protocol of carbonyl compounds has been developed. This protocol affords various a-aryl-a-cyanoacetates, which can be reduced to high-value-added α-aryl-β-amino acids. The cross-coupling reaction of electron-deficient aryl bromides with a-cyanoacetates achieves the expected products with good yields and functional group compatibility under mild conditions. Excessive electron-richness in initial aryl bromides facilitates the self-coupling of desired products. DFT calculations confirm that the presence of electron-rich aryl substitutions decreases the reduction potentials of the product anions, making …

Comparing Proliferation Rates And Collagen Production Of Cells Treated With Cuhars, Katie Elizabeth Mckenzie

Master's Theses

Cartilage is the padding in joints that protects the bones and aids in motion. Problems with the cartilage in the knee can be caused by mechanical damage or diseases like osteoarthritis. Chondrocytes make cartilage. The objective of this study is to determine the doubling time of chondrocytes per passage. I also want to determine the base amount of collagen-II created by chondrocytes as they age. I also want to determine how long it takes CuHARS to break down in different cell medias. Chondrocytes, human dermal fibroblasts, and CRL 2303 cells were grown and cultured for over a year. During that …

Some Reflections On The Application Of Machine Learning To Research Into The Theoretical System Of Mine Water Prevention And Control, Yao Hui, Yin Huichao, Liang Manyu, Yin Shangxian, Hou Enke, Lian Huiqing, Xia Xiangxue, Zhang Jinfu, Wu Chuanshi

Coal Geology & Exploration

The theoretical system of mine water prevention and control encompasses three fundamental aspects: disaster-causing mechanisms, risk evaluation, and disaster prediction. This theoretical system, having undergone rapid development over the past 20 years, aims to gain insights into the behavior characteristics of mine water and predict its evolutionary trend, thus serving the prevention and control of water disasters in mining areas. Applying machine learning, a powerful tool for data analysis and mining in the era of big data, to research into the theoretical system has garnered considerable attention. This study focuses on the specific applications of machine learning to the three …

Evolutionary Mechanisms And Models Of Strain, Porosity, And Permeability Of Compacted Broken Coals, Li Lei, Lu Shouqing, Chu Tingxiang, Zhong Xiaoxing, Liu Chongyang, Ren Ting

Coal Geology & Exploration

Residual coal areas in caving zones of goaves in coal mines serve as primary sites for low-temperature reactions between coal and oxygen. Hence, exploring the evolutionary models of the strain, porosity, and permeability of coals in these areas holds great significance for gaining a deep understanding of the spontaneous combustion process and regularity of coals. Based on the self-developed experimental device for gas seepage in compacted broken coals, this study explored the evolutionary patterns of the strain, porosity, and permeability of compacted coals with single/mixed particle sizes during gas seepage. Furthermore, this study analyzed the variations in the strain, porosity, …

Barriers To Mental Health Treatment Among U.S. Army Aviation Personnel, Aric James Raus

Doctoral Dissertations and Projects

Safe and effective Army aviation operations require a clear focus from all involved. Yet, after more than two decades of U.S. combat aviation operations, little is known about the barriers experienced by aviators when considering mental health evaluation and treatment. An extensive literature review found no published studies examining mental health treatment hesitance among Army Aviation personnel or the perceived acceptability of self-help treatment options. This study identifies the relationships between age, gender, and aviation career specialty on the self-disclosed instrumental, attitudinal, and stigma-based barriers to care among U.S. Army aviation personnel. Additionally, the research determines relationships between the population’s …

Development Of Agar-Based Preformed Particle Gel For Water Control In High-Salinity Reservoirs, Ahmed Ben Ali, Reem Elaf, Abdulaziz A. Almakimi, Mohammed Saad, Ibnelwaleed A. Hussein, Baojun Bai

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Oil Extraction Faces Challenges in Cost and Complexity Due to Excessive Water Production, Leading to Diminished Hydrocarbon Recovery. Preformed Particle Gels (PPGs) Hold Promise for Enhancing Oil Recovery and Sealing High-Permeability or Fractured Zones. However, Current PPGs Encounter Limitations in High-Temperature Reservoirs, Including Salt Sensitivity and Potential Hazards. to Address These Issues, We Propose Eco-Friendly PPGs Utilizing Agar Polysaccharides. Agar Backbones Grafted with Acrylamide (AM) and AM/N,N′-Methylenebis(AM) (MBA) Via Microwave-Assisted Techniques Resulted in Polyacrylamide Grafted Agar (Ag/PAM) and Cross-Linked Polyacrylamide Grafted Agar (Ag/PAMBA). Various Sizes (75 Μm to 1.18 Mm) Were Prepared to Accommodate Diverse Reservoir Porosities and Ensure Effective …

Ensuring Resilience Against Stealthy Attacks On Cyber-Physical Systems, Paul Griffioen, Bruce H. Krogh, Bruno Sinopoli

Faculty Work Comprehensive List

This article provides a tool for analyzing mechanisms that aim to achieve resilience against stealthy, or undetectable, attacks on cyber-physical systems. We consider attackers who are able to corrupt all of the inputs and outputs of the system. To counter such attackers, a response scheme must be implemented that keeps the attacker from corrupting the inputs and outputs of the system for certain periods of time. To aid in the design of such a response scheme, our tool provides sufficient lengths for these periods of time in order to ensure safety with a particular probability. We provide an upper bound …

Analysis Of The Effect Of Different Surface Preparation Methods On Corrosion Resistance And Adhesion Strength Of Astm A36 Steel Substrate With Surface Tolerant Epoxy Paint As Coating Material, Irwan Wijaya Santoso, Daffa Aqila, Rini Riastuti, Rizal Tresna Ramadhani

Journal of Materials Exploration and Findings

In the industrial world, to extend the service life of materials, protection methods are carried out to slow down the material's corrosion rate. The protection method that is often used is the coating method. The coating method is a protection method by coating the substrate material using a coating material to prevent contact between the substrate material and the environment. In this research, the substrate material used is ASTM A36 steel and the coating material used is Surface Tolerant Epoxy paint. The independent variable used in this study lies in the surface preparation method which consists of: solvent cleaning, hand …

Localized Sustained Release Of Copper Enhances Antitumor Effects Of Disulfiram In Head And Neck Cancer, Juan Wang, Boxuan Li, Remy C. Cooper, Da Huang, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Drug Repurposing Uses Approved Drugs as Candidate Anticancer Therapeutics, Harnesses Previous Research and Development Efforts, and Benefits from Available Clinically Suitable Formulations and Evidence of Patient Tolerability. in This Work, the Drug Used Clinically to Treat Chronic Alcoholism, Disulfiram (DSF), Was Studied for its Antitumor Efficacy in a Copper-Dependent Manner. the Combination of DSF and Copper Could Achieve a Tumor Cell Growth Inhibition Effect Comparable to Those of 5-Fluorouracil and Taxol on Head and Neck Cancer Cells. Both Bulk Dendrimer Hydrogel and Microsized Dendrimer Hydrogel Particles Were Utilized for the Localized Sustained Release of Copper in the Tumor Site. the …

Development Of 485 Mpa Class High Strength Low Alloy Steel For Power Plant Infrastructures, Agung Baskoro, Rini Riastuti

Journal of Materials Exploration and Findings

Currently, Indonesia is progressing to build 35,000 MW of power plants, which will increase the demand for materials, especially steel. One of these power plants is fossil fuel-based, which generates not only electricity but also flue gas containing sulfur that may cause corrosion to power plant infrastructure such as chimney or boiler areas. In addition, apart from being resistant to corrosion in sulfuric and hydrochloric acid conditions, the steel used in power plant infrastructure must also have good strength, toughness, and weldability. Therefore, the present paper describes about steel development for power plant applications that has not only corrosion resistance …

Data-Driven Insights Into Spatial Patterns And Disease Etiologies Of White Matter Hyperintensities, Sugandha Roy

McKelvey School of Engineering Graduate Student Theses & Dissertations

In this thesis, we have applied Orthogonal Projective Non-Negative Matrix Factorization (opNMF) to identify spatial patterns of white matter hyperintensities (WMH) within UK Biobank's imaging data. Our selection criteria excluded subjects with a history of neurological, mental, and specific cerebrovascular conditions, allowing us to focus on WMH patterns in a healthy aging population. We have interrogated the association of location-specific WMHs with a variety of demographic, clinical, and genetic factors. Our multivariable regression analysis evaluates the strength and nature of the associations between these factors and WMH distribution. The analysis integrates variables such as age, sex, smoking habits, medication usage …

Electrospun Shape Memory Fibers For Chronic Wound Surveillance, Avery Gunderson

Theses - ALL

Approximately 6 million patients suffer from chronic wounds each year. These wounds are highly susceptible to infection and subsequent biofilm formation. Biofilms are difficult to dislodge due to their protective extracellular matrix. Antibiotics cannot penetrate the biofilm matrix, so wound healing is often compromised. Current surveillance and treatment options, such as swabbing or dressings, are ineffective and often painful to the patient. Our approach is to employ a bacterial protease-responsive shape memory polymer (SMP) that combats biofilm formation and helps the healing process proceed. To aid in protease penetration and enhance wound dressing comfort, electrospinning can be used to produce …

Urban Scale Vehicle-To-Building-To-Grid Integration Leveraging Human Mobility Modeling, Yapan Liu

Dissertations - ALL

In the United States (U.S.), the buildings sector consumes about 76% of electricity use and 40% of all primary energy use and associated greenhouse gas emissions. Occupant behavior, which includes the presence of people in the space, interactions between the occupant and building systems, and occupant adaptations to the built environment, has a significant impact on the energy consumption of buildings. Many researchers have investigated occupant behaviors at a single building scale, however, very few studies have been conducted at the community scale or urban scale. Our previous review study introduced human mobility modeling approach from other domains into the …

Multi-Scale Analysis Of The Structure-Mechanics Relationship Of Mycelium-Based Bio-Composites, Libin Yang

Dissertations - ALL

The construction industry faces significant challenges due to the environmental impact of traditional materials like steel and concrete, whose production is energy-intensive and contributes to environmental pollution. This issue is exacerbated by the growing global demand for construction materials, driven by an increasing population. Concurrently, the agricultural and wood industrial sectors produce vast byproducts, such as straw, husk, coir, sawdust, and wood chips. They are often considered as wastes and disposed of through methods like burning. Such a reckless treatment releases greenhouse gases that further lead to environmental degradation. Mycelium, the vegetative part of fungi, presents a natural, promising solution …

Synthesis And Design Of High-Silica Pd-Containing Zeolites For The Catalytic Combustion Of Methane, Jingzhi Liu

Dissertations - ALL

Greenhouse gases, notably carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O), are principal contributors to global warming, leading to an incremental rise in Earth's atmospheric temperature. The escalation of these gases, primarily from fossil fuel combustion, deforestation, and industrial processes, enhances the radiative forcing mechanism, thereby trapping excessive solar heat within the atmosphere. Scientific inquiries into the spectral absorption properties and life span of these gases emphasize their varying impacts on Earth's thermal equilibrium. For instance, CO2, with its extensive atmospheric residency, brings a prolonged thermal influence, whereas CH4, while being the cleanest burning fossil fuel that generates far …

Engineering The Signal Resolution Of A Paper-Based Cell-Free Glutamine Biosensor With Genetic Engineering, Metabolic Engineering, And Process Optimization, Tyler J. Free, Joseph P. Talley, Chad D. Hyer, Catherine J. Millar, Joel S. Griffitts, Bradley Charles Bundy

Faculty Publications

Specialized cancer treatments have the potential to exploit glutamine dependence to increase patient survival rates. Glutamine diagnostics capable of tracking a patient’s response to treatment would enable a personalized treatment dosage to optimize the tradeoff between treatment success and dangerous side effects. Current clinical glutamine testing requires sophisticated and expensive lab-based tests, which are not broadly available on a frequent, individualized basis. To address the need for a low-cost, portable glutamine diagnostic, this work engineers a cell-free glutamine biosensor to overcome assay background and signal-to-noise limitations evident in previously reported studies. The findings from this work culminate in the development …

Effect Of Recommending Users And Opinions On The Network Connectivity And Idea Generation Process, Sriniwas Pandey, Hiroki Sayama

Northeast Journal of Complex Systems (NEJCS)

The growing reliance on online services underscores the crucial role of recommendation systems, especially on social media platforms seeking increased user engagement. This study investigates how recommendation systems influence the impact of personal behavioral traits on social network dynamics. It explores the interplay between homophily, users’ openness to novel ideas, and recommendation-driven exposure to new opinions. Additionally, the research examines the impact of recommendation systems on the diversity of newly generated ideas, shedding light on the challenges and opportunities in designing effective systems that balance the exploration of new ideas with the risk of reinforcing biases or filtering valuable, unconventional …

Engineering Composite Gridlines For Improved Solar Module Reliability, Andre Chavez

Electrical and Computer Engineering ETDs

Renewable energy sources, such as solar power, are rapidly expanding worldwide to meet increased energy demands. However, these sources are exposed to challenging environmental stressors, such as extreme wind, heavy snow loads, and hailstorms that can cause irreversible damage to the crystalline semiconductor solar cells. Today, single crystalline silicon solar cells dominate the market, and our work is focused on improving their reliability against environmental stressors. One of the main degradation mechanisms caused by environmental stressors is cell cracks. These microcracks can go virtually undetected and lead to reduced power output from solar modules over time. To solve this engineering …

The Santa Clara, 2024-05-10, Santa Clara University

The Santa Clara

No abstract provided.

Effects Of Print Process Parameters On Droplet-Powder Interaction In Binder Jet Additive Manufacturing, Jacob Lawrence

Theses and Dissertations

Binder jet additive manufacturing (BJ) offers unique advantages, including the ability to produce complex geometries and utilize a wide range of materials, but faces challenges related to part quality and defect formation. This thesis investigates the effects of process parameters on droplet-powder interaction, powder relocation, and line formation in BJ printing. A custom BJ test platform was developed to enable precise control over key process parameters and in-situ monitoring. High-speed synchrotron X-ray imaging revealed modes of powder relocation above and below the powder bed surface. Testing revealed that parameters that increase moisture in the powder bed, such as lower droplet …

Development Of A Rapid Bacterial Quantification Method Based On Droplet Microfluidics, Shawn Bliss

Electronic Theses and Dissertations

The capacity to identify bacteria quickly and accurately is critical for applications such as medical diagnosis, environmental monitoring, and food safety. For instance, sepsis diagnosis requires blood cultures that take as long as 1-5 days, preventing timely intervention and increasing mortality rate. Here, we propose the joint use of microfluidics and a machine learning algorithm for rapid bacterial cell capture and quantification. The combination of high-throughput droplet microfluidics and a support vector machine (SVM) enables analysis and quantification of bacterial samples within as short as 4 hours. We have performed successful encapsulation of pathogenic bacteria such as E. coli, …

Latent Auto-Recursive Composition Engine, Yenkai Huang

Dartmouth College Master’s Theses

This thesis investigates the shifting boundaries of art in the era of Generative AI, critically examining the essence of art and the legitimacy of AI-generated works. Despite significant advancements in the quality and accessibility of art through generative AI, such creations frequently encounter skepticism regarding their status as authentic art. To address this skepticism, the study explores the role of creative agency in various generative AI workflows and introduces an "artist-in-the-loop" system tailored for image generation models like Stable Diffusion. This system aims to deepen the artist's engagement and understanding of the creative process. Additionally, a novel tool, the Latent …

Calcium Analysis Of Intercellular Communications Between Alpha Cells And Delta Cells Across The Pancreatic Islet, Shichao Gao

McKelvey School of Engineering Graduate Student Theses & Dissertations

The intricate communication between different cell types within pancreatic islets plays a crucial role in regulating glucose homeostasis. Among these cellular interactions, the interplay between α cells (responsible for glucagon secretion) and δ cells (secreting somatostatin) is particularly intriguing due to the inhibitory effects of somatostatin on glucagon release. Understanding the intercellular interactions between α and δ cells may provide insights into the mechanisms underlying the coordinated regulation of blood glucose levels. In this study, we employed a multi-modal approach combining confocal imaging, image analysis, and correlation network analysis to investigate the spatial relationships and potential functional connections between α …

Variable Design Stent To Prevent Stent Failure In Areas Of High Mobility In Peripheral Artery Disease Patients, Emmie Stevens, Brennan Toepfer, Lexi Graves

Honors Theses

As senior biomedical engineering students at the University of Mississippi, we were tasked with a senior project to find an unmet clinical need in the healthcare industry and design a way to solve it. Our team, consisting of Hannah Dunn, Lexi Graves, Emmie Stevens, and Brennan Toepfer, decided to improve upon current stents to create a stent more suited to treating Peripheral Artery Disease (PAD), especially in high-impact areas, such as the back of the knee joint. Stents placed in the back of the knee have a high level of stent failure due to the high movement of the knee …

An Overview Of The Product Development Process For A Lounging Grove Chair: The Rebel Lounge, Gracey Massengill

Honors Theses

This report focuses on the process of completing my senior capstone project for the Center for Manufacturing Excellence with my teammates, Andrew Brady, Carter Doss, Brooke Grissinger, and Karson Wardell. It explains the development, design and manufacturing of the Rebel Lounge Chair, a comfortable, portable and versatile chair made with the University of Mississippi Grove in mind and the prospective customers that would purchase such a chair. The report describes the phases of brainstorming, market research, prototyping, manufacturing process development, and accounting analysis that the Rebel Lounge capstone team went through to create their product.

Due to out-of-the-box brainstorming and …

Population At Risk: The Design And Production Of The Pollinator Plaza, Shane Houston Stephens

Honors Theses

This report focuses on the development and manufacturing of the Pollinator Plaza, a high-quality bug house created to combat pollinator population loss. According to countless studies, pollinator populations have seen a dramatic decrease in recent years, and this product was developed to address these alarming statistics by providing a suitable habitat for pollinators. A market analysis was used to identify our potential clientele and cost point. This research played an integral part in the design of the Pollinator Plaza, which was developed using AutoCAD software. This design became a reality through the construction of a physical prototype.

The Pollinator Plaza’s …

Synthesis And Analysis Of A Novel Magnetic Surfactant, Donovan Turpin

Honors Theses

Researchers in the University of Mississippi Chemical Engineering Department have suggested that chelation of a large magnetic transition metal, namely dysprosium, into the large polar head group of a surfactant could result in a magnetic surfactant. This project was aimed at synthesizing a surfactant with a large enough head group and negative charge (specifically EDTA) to support this ion and demonstrating that the chelation process was successful. If so, the molecule would ideally be capable of forming micelles which could extract oily substances from water using a strong magnet—possibly applicable to environmental crises like oil spills.

NMR analysis has suggested, …