Digital Commons Network^™

Hagfish Protein Models Of Heart Tissue Reveal Processes Of Diabetes, Maelyn Andreasen

Research on Capitol Hill

Diabetic cardiomyopathy impairs and damages heart tissue through chronic exposure to hyperglycemia, or high blood sugar, in diabetic individuals. 

Studying the disease in heart tissue is difficult, so we set out to create a three-dimensional heart model that we can study under these hyperglycemic conditions.

Introduction To Drones, Shawn Barstow, Justin Wyatt Clawson, Shalyn Drake, Eric Galloway, Michael Pate

All Current Publications

Unmanned aircraft have advanced so much that they are completing tasks and integrating into all aspects of our lives. They deliver, survey, collect data, and complete assigned tasks with more efficiency and lower cost than many currently used techniques. The Federal Aviation Administration (FAA) completely supports UAS in the National Airspace System (NAS) and continually updates information in this new and exciting field. This fact sheet will help you identify how you can legally fly drones and become an integral part of aviation’s vast and ever-progressing world.

Stanag 4575 Cst M35, Will Scheirer, Lee Sublett, George Weiss, Tina Howell, Ben Hill, Jared Sanders

Space Dynamics Laboratory Publications

General Information

➢ Provides a standardized “direct data download” capability from any NADSI compliant ISR data acquisition recorder to a compliant ground station

➢ STANAG 4575 Ed.4 became a mandated DISR standard for US DoD organizations on 24 April 2018; STANAG 4575 Ed. 5 is currently under JCGISR silence procedure until 14 February

➢ Magnetic Disk, Solid State, Complete Units, or Removable Media Modules (RMMs); Non-proprietary Directory and File Structure

➢ Based On Commercial Gigabit Ethernet Standards TCP/IP and Fiber Channel

Ongoing Efforts

➢ Working NADSI Ed.5 implementation with various national and international industry partners and manufacturers

➢ Further NADSI …

Interfacial Phenomena In Molten Salt Systems And Wetting Transitions In Microcavities, Aaron Essilfie

Theses and Dissertations

Interfacial phenomena are the processes that occur at the interface between two phases of matter: solid-liquid, solid-gas, liquid-liquid, and liquid-gas. Wetting, spreading, adsorption, and capillarity are some features of interfacial phenomena. This research explores two areas of interfacial phenomena: the interfacial tension between a liquid and gas, and wetting transitions in microcavities. Surface tension has been a widely studied topic in surface chemistry. Many techniques have been employed to study the surface tension of liquids in various studies and research areas, but the interfacial tension between a liquid and gas has not been extensively researched. For this reason, part of …

Recent Developments In Heterologous Expression Of Cellulases Using The Pichia Pastoris Expression System: A Comprehensive Literature Review, Nazish Muzaffar, Abdur Raziq, Muhammad Waseem Khan, Niaz Muhammad Khan, Bushra Shahid, Anbareen Gul, Hayat Ullah

Biological Engineering Student Research

Cellulosic biomass is considered an important and sustainable source of renewable energy, which needs a complex mixture of different enzymes for its degradation. After amylase, cellulases are the second most important enzymes, gain more importance due to their broad range of applications at the industrial level, and are considered more economical and environmentally friendly; researchers have focused more on the production of cellulase with its higher expression rate and low cost. Pichia pastoris, a methylotrophic yeast strain, has a more effective and well-established system for the production of heterologous proteins, particularly for industrial enzymes. Moreover, its readily achievable high-density …

Prediction And Control Of Ground Vibrations Due To Blasting Activities In Aggregate Mines, Iddi Ramadhani Bulushi, Geleta Warkisa Deressa, Bhanwar Singh Choudhary

Journal of Sustainable Mining

Predicting and controlling ground vibrations from blasting is crucial for protecting structures and minimizing environmental impacts. This study investigates how explosive quantity and scaled distances affect peak particle velocity and establishes empirical equations to estimate this velocity at different distances from the blast area. The study found that the maximum charge per delay at a peak particle velocity of 10 mm/s was reduced to 13.46% as the delay timing was increased from 0 to 25 ms and 9.99% from 0 to 50 ms delay timing. The reduction of maximum charge with increasing delay timing leads to the reduction of ground …

Super-Resolution Imaging Reveals Resistance To Mass Transfer In Functionalized Stationary Phases, Ricardo Monge Neria, Muhammad Zeeshan, Aman Kapoor, Tae Kyong John Kim, Nichole Hoven, Jeffrey Pigott, Burcu Gurkan, Christine Duval, Lydia Kisley

Faculty Scholarship

Chemical separations are costly in terms of energy, time, and money. Separation methods are optimized with inefficient trial-and-error approaches that lack insight into the molecular dynamics that lead to the success or failure of a separation and, hence, ways to improve the process. We perform super-resolution imaging of fluorescent analytes in five different commercial liquid chromatography materials. Unexpectedly, we observe that chemical functionalization can block more than 50% of the material’s porous interior, rendering it inaccessible to small-molecule analytes. Only in situ imaging unveils the inaccessibility when compared to the industry-accepted ex situ characterization methods. Selectively removing some of the …

Integrating Fuzzy Set Theory With Association Rule Mining For Advanced E-Commerce Recommendations, Hind Raad Ibraheem, Murtadha Mohammed Hamad

Iraqi Journal for Computer Science and Mathematics

The dynamic nature of e-commerce necessitates the adoption of cutting-edge technologies to improve the online shopping experience. Our research introduces a groundbreaking methodology called Fuzzy Association Rule Mining (FARM), combining fuzzy set theory with traditional Association Rule Mining (ARM). Unlike conventional ARM, which focuses solely on the frequency of jointly purchased items, FARM also considers the sold quantities, leveraging the Apriori algorithm to discern customer preferences from historical sales data across the UCI Online Retail II, Market Basket, and Movielens datasets. This hybrid of fuzzy set theory with ARM enables a better understanding of complicated consumer behaviors and associations between …

Email Spam Classification Based On Deep Learning Methods: A Review, Ekramul Haque Tusher, Mohd Arfian Ismail, Anis Farihan Mat Raffei

Iraqi Journal for Computer Science and Mathematics

Email spam is a significant issue confronting both email consumers and providers. The evolution of spam filtering has progressed considerably, transitioning from basic rule-based filters to more sophisticated machine learning algorithms. Deep learning has become a potent collection of techniques for addressing intricate issues such as spam classification in recent times. A thorough literature evaluation is required to have a comprehensive overview of the current research on utilizing deep learning methods for email spam classification. This review aims to identify the various deep learning techniques used for email spam, their effectiveness, and areas for future research. By synthesizing the outcomes …

Trpv4 Dominates High Shear-Induced Initial Traction Response And Long-Term Relaxation Over Piezo1, Mohanish Chandurkar, Manli Yang, Majid Rostami, Sangyoon J. Han

Michigan Tech Publications

Modulation of endothelial traction is critical for the responses of endothelial cells to fluid shear stress (FSS), which has profound implications for vascular health and atherosclerosis. Previously, we demonstrated that under high FSS, endothelial cells rapidly increase traction forces, followed by relaxation, with traction aligning in the flow direction. In contrast, low shear preconditioning induces a modest short-term increase in traction (min), followed by a secondary long-term (>14 hr) rise, with traction/cells aligning perpendicular to the flow. The upstream mechanosensors driving these responses, however, remain unknown. Here, we sought the roles of Piezo1 and TRPV4 ion channels in shear-induced …

Iros 2023 Workshop Report: Draft Guidelines On Manufacturing Procedures, Test Methods And Reporting For Soft Robotics, Robert Baines, Laura Blumenschein, Jennifer Case, Robert Maccurdy, Gina Olson, Andrew Spielberg

School of Mechanical Engineering Working Papers

No abstract provided.

Internet Of Things Devices Users’ Privacy Adherence: A Case Of Digital Ignorance, Akrasia Or Exhaustion?, Philip Bazanye, Walter F. Uys, Wallace Chigona

The African Journal of Information Systems

Internet of Things devices, such as those used in home automation, commercial and retail business, and smart cities, are vulnerable to attacks that affect all aspects of daily life. The upsurge in the use of IoT devices has increased the likelihood of cyber-attacks on end users. This research investigates the factors that influence IoT device users to adhere to privacy standards. This interpretivist exploratory research was guided by a three-phased approach. The interview questions were derived from the conceptual model and the constructs of Activity Theory, and themes were analyzed using deductive thematic analysis. The findings were elaborated with reference …

Can Chatgpt Implement Finite Element Models For Geotechnical Engineering Applications?, Hyoung Suk Suh

Faculty Scholarship

This study assesses the capability of ChatGPT to generate finite element code for geotechnical engineering applications from a set of prompts. We tested three different initial boundary value problems using a hydro-mechanically coupled formulation for unsaturated soils, including the dissipation of excess pore water pressure through fluid mass diffusion in one-dimensional space, time-dependent differential settlement of a strip footing, and gravity-driven seepage. For each case, initial prompting involved providing ChatGPT with necessary information for finite element implementation, such as balance and constitutive equations, problem geometry, initial and boundary conditions, material properties, and spatiotemporal discretization and solution strategies. Any errors and …

Evolution Of Lyrics Of Egyptian Songs In The 20th Century, Omar Abdelrafe

The Undergraduate Research Journal

Despite the extensive research by western countries on the song lyrics, almost nothing is known about the evolution of Egyptian song lyrics. The previous studies in the U.S. and U.K. revealed that lyrics were more pessimistic as time passed. In this study, 1891 Egyptian songs from 1920 to 2022 were analyzed using a sentiment analysis tool while searching for offensive words and retrieving their popularity scores from Spotify. The results aligned with those of the other regions in which the negativity of songs and the percentage of songs containing offensive words increased. However, there is a substantial increase in neutral …

Streamlined Production, Protection, And Purification Of Enzyme Biocatalysts Using Virus-Like Particles And A Cell-Free Protein Synthesis System, Seung O. Yang, Joseph P. Talley, Gregory H. Nielsen, Kristen M. Wilding, Bradley Charles Bundy

Faculty Publications

Enzymes play an essential role in many different industries; however, their operating conditions are limited due to the loss of enzyme activity in the presence of proteases and at temperatures significantly above physiological conditions. One way to improve the stability of these enzymes against high temperatures and proteases is to encapsulate them in protective shells or virus-like particles. This work presents a streamlined, three-step, cell-free protein synthesis (CFPS) procedure that enables rapid in vitro enzyme production, targeted encapsulation in protective virus-like particles (VLPs), and facile purification using a 6× His-tag fused to the VLP coat protein. This process is performed …

Using Unmanned Aerial Vehicles To Facilitate Traffic Incident Management, Adam William Hill

Theses and Dissertations

Incident management teams (IMTs) minimize crash impacts and create a safer highway network for people and communities. Research has shown that optimizing the IMT fleet has strong benefits to the roadway network, but future models indicate that increasing IMT presence may have diminishing returns after excessive roadway saturation. The Utah Department of Transportation (UDOT) would like to improve situational awareness in areas of poor or limited camera coverage, where situational awareness is typically poor. UDOT is considering the use of unmanned aerial systems (UAS) to provide live camera coverage of traffic conditions in these instances. This thesis synthesizes practice from …

A Review On Exploring Artificial Intelligence Applications, Advancements, Issues, And Future Challenges, Sajid Naeem, Novman Nabeel, Waseem Beg, Shujaat Ali, Rajiv N. Kanojiya, Satish S. Mandawade, Chetan R. Yewale, Sc Kulkarni, Vt Salunke, Av Patil

Polytechnic Journal

Artificial intelligence (AI) is a transformative technology with diverse applications that is transforming several industries. AI is the use of systems and technology to replicate human intelligence and solve common real-world issues. Machine learning (ML) and deep learning are AI technologies that use algorithms to more accurately predict occurrences without the need for human intervention. Explainable Artificial Intelligence (XAI) refers to AI that can explain decisions or forecasts to human users. XAI seeks to improve AI systems' transparency, trustworthiness, and accountability, particularly when utilized in high-risk applications such as healthcare, finance, or security. This review article provides a thorough overview …

Selective Leaching Of Rare Earth Elements From Complex Rare Earth Ore Using Deep Eutectic Solvents, Frank Agyemang, Mehran Saddat, Zainab Nasrullah, Richard Ladouceur

Metallurgical & Materials Engineering

Rare earth elements (REEs) are valuable for various modern technological applications, including metallurgy, machine building, radio electronics, instrument engineering, nuclear engineering, and manufacturing. The extraction and separation of rare earth elements (REEs) from their complex ores is challenging due to their distinct physical and chemical properties, contributing to their market scarcity. At present, REE recovery utilizes traditional pyro- or hydrometallurgical processes. The overall process in the recovery and separation of individual elements from complex REE systems suffers from high energy demands and the use of many hazardous chemicals that negatively impact the environment. With the growing trend toward a circular …

Process Intensification By Resonant Vibratory Mixing For The Recyclable Samarium - Cobalt Magnets After Chemical Leaching With Deep Eutectic Solvents, Zainab Nasrullah, Frank Agyemang, Mehran Saddat, Richard Ladouceur

Metallurgical & Materials Engineering

To sustain the circular economy, defense applications, and other renewable technologies, recycling rare earth elements (REEs) and other critical elements from their secondary resources is important. This cause has resulted in rigorous research and development for viable extraction and separation of REEs. Previously, Sm-Co recycling has been done with technologies, which fall under the categories of pyrometallurgy, physical separation, and hydrometallurgy. All these methods have limitations associated with energy, cost, and environment. Reportedly, the chemical leaching technology has successfully recovered and separated Sm-Co. Still, it has limitations associated with slow mass transfer and leaching kinetics, and there is a need …

Nh Stormwater Manual 2025, Unh Stormwater Center, Comprehensive Environmental Inc., Nh Department Of Environmental Services

UNH Stormwater Center

No abstract provided.

Building Services Engineering January/February 2025

Building Services Engineering

No abstract provided.

Oxidation–Reduction Of Ti-6al-4v In Direct Energy Deposition Subject To Minimum Argon Consumption, Bharadwaja Ragampeta, Prashansa Ragampeta, Todd Sparks, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Ti-6Al-4V is a well-known alloy for its low density and excellent corrosion resistance, making it popular in aerospace, marine, medical, and automotive applications. However, at elevated temperatures, the alloy forms oxides, leading to embrittlement. In additive manufacturing, particularly in the direct energy deposition (DED) process, which involves high temperatures, the alloy experiences oxidation. An inert gas chamber provides shielding during the process but limits the size of the manufactured components, and deposition in a vacuum chamber can alter the chemical composition of the alloy. Local shielding is a technique generally used for such applications, but it uses a high volume …

The Hidden Cost Of Using Time Series Aggregation For Modeling Low-Carbon Industrial Energy Systems: An Investors’ Perspective, Markus Fleschutz

Publications

Time series aggregation (TSA) is commonly used in energy system optimization to reduce model complexity and computational expenses by selecting periods to represent the entire time series. TSA’s accuracy has traditionally been assessed by comparing the objective values between the original and TSA models (assumed error). However, evaluating TSA from an investor’s standpoint involves analyzing the performance of TSA-based energy system designs using the original time series. Therefore, we introduce the hidden error and total error, novel error metrics, to evaluate the financial implications of TSA through backtesting the TSA-based system designs using the original time series. Our analysis extends …

Membrane Filtration Of Nanoscale Biomaterials: Model System And Membrane Performance Evaluation For Aav2 Viral Vector Clarification And Recovery, Mara Leach, Kearstin Edmonds, Emily Ingram, Rebecca Dutch, Sumith R. Wickramasinghe, Malgorzata Chwatko, Dibakar Bhattacharyya

Chemical Engineering Faculty Publications and Presentations

The growing demand for viral vectors as nanoscale therapeutic agents in gene therapy necessitates efficient and scalable purification methods. This study examined the role of nanoscale biomaterials in optimizing viral vector clarification through a model system mimicking real AAV2 crude harvest material. Using lysed HEK293 cells and silica nanoparticles (20 nm) as surrogates for AAV2 crude harvest, we evaluated primary (depth filters) and secondary (membrane-based) filtration processes under different process parameters and solution conditions. These filtration systems were then assessed for their ability to recover nanoscale viral vectors while reducing DNA (without the need for endonuclease treatment), protein, and turbidity. …

Mixed Ion-Electron Conducting Lixag Alloy Anode Enabling Stable Li Plating/Stripping In Solid-State Batteries Via Enhanced Li Diffusion Kinetic, Anran Cheng, Pei Gao, Ruxing Wang, Kangli Wang, Kai Jiang

EKU Faculty and Staff Scholarship

Although showing huge potential in prospering the marketplace of all-solid-state lithium metal batteries (ASSLMBs), garnet-type solid electrolytes (Li6.5La3Zr1.5Ta0.6O12, LLZTO) are critically plagued by interface instability with Li anode and the vulnerability to Li dendrite, which are attributed to poor Li diffusion kinetic in bulk Li metal. Herein, a LixAg solid solution alloy with high Li diffusion kinetic is reported as a mixed ion- electron conductor (MIEC) alloy anode. The high Li diffusion kinetic stemming from a low eutectic point and a high mutual solubility of LixAg could reduce the Li concentration gradient in the anode, regulate Li electrochemical potential, and …

Phase Of The Seabed Frequency-Domain Reflection Coefficient: Measurements And Modeling, Charles W. Holland

Electrical and Computer Engineering Faculty Publications and Presentations

The phase of the seabed frequency-domain reflection coefficient potentially contains valuable information on the geoacoustic properties in a layered/refracting seabed. However, heretofore, the phase has not been exploited. Measurements of phase are presented in an area of thick mud at the New England Mud Patch. In addition, a model is presented along with the modeling results. While this is only a first step towards understanding the potential value of exploiting the phase, it seems clear that in some instances, the phase not only contains valuable geoacoustic information, but carries a higher information content than the magnitude.

Meso-Damage Characterization Of Chemically Corroded Rocks Under Unloading Confinement Conditions, Hao Li, Leo Pel, Zhenjiang You, David Smeulders

Research outputs 2022 to 2026

Characterizing meso-damage and understanding its correlation with macroscopic mechanical responses of rocks under coupled chemical-mechanical (C-M) conditions are crucial for the stability analysis and safety design of underground constructions in chemically corrosive environments. This research proposes a model to quantify coupled C-M meso-damage of rocks, utilizing geochemical surface reaction theory, statistical mechanics, thermodynamic principles, and novel principals proposed in this study, termed Random Energy Release Rate (RERR) and Effective Chemical Damage (ECD). To achieve this goal, a multiscale experimental investigation, including Nuclear Magnetic Resonance (NMR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), pH and ion chromatography analysis, triaxial compression and …

Why Are Fairness Concerns So Important? Lessons From A Last-Mile Transportation System, Yiwei Chen, Hai Wang

Research Collection School Of Computing and Information Systems

The Last-Mile Problem refers to the provision of travel service for passengers from the nearest public transportation node to the final destination. The Last-Mile Transportation System (LMTS), which has recently emerged, provides on-demand last-mile transportation service for passengers. We consider an LMTS that consists of two types of passengers, regular-type passengers and special-type passengers (e.g., seniors, disabled people). The valuation of the last-mile service for special-type passengers is statistically higher than the one for regular-type passengers. Passengers incur disutility from waiting for the last-mile service. In this paper, we explore two fairness constraints on special-type passengers: (1) the fare for …

Multi-Scale Modeling Of Transport Properties In Cementitious Materials With Go Admixture, Bing Liu, Weichen Kang, Weixing Lian, Feng Xing, Hongfang Sun, Hongyan Ma

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

In coastal areas, the presence of concrete cracks provides pathways for hazardous ions to ingress from the exterior into the interior of concrete, while the migration of the ions further accelerates concrete deterioration and causes durability problems. The incorporation of graphene oxide (GO) into concrete can inhibit crack initiation and development starting at the nanoscale, improving the concrete microstructure, thereby affecting concrete's resistance to hazardous ion transport and the resulting deterioration. In this study, a multi-scale transport model for cementitious materials with a GO admixture was established to predict the resistance to hazardous ions. Based on the determination of hydration …

Simulation-Based Models For Postearthquake Response: A Survey And Research Directions, Abhijit Gosavi, Lauryn A. Spearing, Lesley H. Sneed

Engineering Management and Systems Engineering Faculty Research & Creative Works

Computer simulation is increasingly being used by emergency planners as a tool to improve disaster response given that it can model real-world scenarios, such as earthquakes. Although there has been an increase in simulation research focused on disaster response, much of this literature is from disparate fields and across disaster scenarios. To bridge this gap, this paper surveys simulation-based models for post-earthquake response from the year 2000 onward. Advantages of simulation over closed-form statistical models are discussed. Three main subproblems in post-earthquake response models are explored: (1) service distribution (e.g., food, water), (2) infrastructure restoration (at the building and transportation …