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Selective Targeting Of Microglia By Quantum Dots And Green Synthesis Of Metal Organic Biohybrids; Applications In Dynamic Cell And Assay Systems, Navya Uppu

Doctoral Dissertations

Neurological disorders are the leading cause of physical and cognitive disability across the globe, currently affecting approximately 15% of the worldwide population. Part of the glioma microenvironment are microglia, resident immune cells of the CNS that were thought to be involved in the pathogenesis of diverse neurodegenerative diseases. Though it remains uncertain what triggers microglial activation in these disorders, targeting and tracking microglial functions using nanotools like Quantum Dots (QDs) could help us elucidate them in such neurological diseases. This research focuses on the comparative study of different QDs formulations and their selective uptake by brain microglia in primary cultures …

Towards Safer Nanomedicine: Embracing Safety-By-Design In Biomedical Research, Mugdha Kulkarni

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Safe Use Of Nanomaterials: A Review On Nanotoxicity And Nanosafety, Punith Krishna Alahari

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Nanotechnology In Food Science: Opportunities And Challenges, Raksha S Shettigar, Usha Yogendra Nayak

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Nanobiorevolution In The Cosmos: Medicine's Quantum Leap To The Stars, Rishabh Agarwala, Ankitha Suresh, Bhisham Narayan Singh

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Experiment, Characterization And Applications Of Bio-Enzymes Derived From Fruit Waste, Chakkati Swayam Raj Yadav, Sai Raj Matta, B.V.S. Praveen

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Implantable And Inhalable Nano-Scale Biosensors For Point-Of-Care Diagnosis, Jyothsna Manikkath

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Nanoelectronics In Healthcare: Recent Updates, Gurram Gnaneshwari, Virendra S Ligade

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

A Natural Interaction Paradigm To Facilitate Cardiac And Nerve Anatomy Education Using Augmented Reality And A Surgical Metaphor, Shashikala S V, Amith D, Lekhana H L, Disha T S, Likith R

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Fate, Safety And Toxicity Of Nanoparticles Exposure To Human, Adresha Saha, Usha Y Nayak

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Nanomedicine – A Regulatory Landscape, Prerana V Poojary, D Sreedhar

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Cnts/Polymer Composite Coated Cotton Fabrics For Emi Shielding Applications – A Short View Of Contemporary Review, N R Dhineshbabu, V S Prabhin

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Chemical And Green Synthesis Of Cuo Nanoparticles And Its Impact On Pearl Millet Seed Germination And Morphological Traits, Harsha K Chandrashekhar, Gunjan Singh, Arya Kaniyassery, Thorat Sachin Ashok, Roopa Nayak, Thokur Sreepathy Murali, Annamalai Muthusamy

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Lighting The Path To Precision: Nanophotonics In Medicine, Sharanya ., Usha Y Nayak

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

In Silico Modelling And In Vitro Characterization To Develop A Novel Drug Which Can Inhibit One Of The Principal Protein Translation Machineries, M7g-Eif4e - An Innovative Approach, Saradindu Banerjee, Krishnaprasad B, Shrilaxmi Ms, Archana Bm, Yogendra Nayak, Somasish Ghosh Dastidar

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Global Regulatory Prospective Of Nano Cosmeceuticals, Santosh Marennavar

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Nanomaterials For 3d Printing Nano- And Micro-Porous Silicon-Based Glass And Ceramics, Vipul Gupta, Ahmad Norouzi, Brett Paull

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Revolutionizing Early Leaf Disease Detection And Classification: An In-Depth Survey Of Innovative Strategies Leveraging Residual Networks For Unprecedented Precision, Efficiency, And Robustness In Machine Learning-Driven Plant Health Monitoring., Sita Yadav, Abhijit Singh, Aniket Digole, Megha Kumari, Ritika Pandey

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Nano Sunscreens: Role Of Nanotechnology, Recent Advancements And Regulatory Overview, Chesta Agarwal, Virendra S Ligade

International Conference on ‘NANOSCIENCE AND NANOTECHNOLOGY'

No abstract provided.

Interpatient Differences In Neural Recruitment Patterns During Pudendal Nerve Stimulation – A Computational Investigation, Amolak S. Jhand, Luis C. Ruiz, Nystha Baishya, Ehsan Mirzakhalili, Gaurang Shah, Priyanka Gupta, Tim M. Bruns, Scott F. Lempka

Medical Student Research Symposium

Bladder dysfunction impairs the quality of life for millions of individuals around the world. Common causes of bladder dysfunction include aging, trauma, and neurological disorders. Due to inadequacies in conventional treatments, neuromodulation therapies to address bladder dysfunction, such as sacral nerve stimulation, have emerged. However, patient needs still remain unmet. Pudendal nerve stimulation (PNS) has recently gained clinical interest as a promising treatment for bladder dysfunction. While PNS has been extensively investigated in preclinical settings, there is a gap in our understanding of the mechanisms of action and efficacy of PNS as limited studies of PNS have been performed on …

Comparison Of Scanning Electron Microscopy And Confocal Laser Microscopy For Tissue Surface Roughness Characterization, Tarnvir Dhaliwal

Master's Theses

It was found that the measurements captured by confocal microscopy and scanning electron microscopy had a statistically significant difference for bovine tissue. There was not a statistically significant for porcine and poultry tissue.

The intent of the study is to perform a comparative study to examine efficacy of two distinct technologies for a singular purpose: tissue surface roughness characterization. The two technologies compared are a confocal reflectance microscope and a scanning electron microscope. The comparison was made by comparing two surface roughness parameters [Ra and Rq] within ImageJ.

The study examined three different animal species [porcine, bovine, and poultry] to …

Development Of An In Vitro 3-Dimensional Co-Culture Human Colorectal Cancer Model In Microfluidic Devices, Abby Jens

Master's Theses

Colorectal cancer is the second most common cause of cancer-related deaths in the United States, with the relative 5-year survival rate for distant stage cancer being only 14%. The most common treatment for colorectal cancer is with chemotherapeutic drugs; however, the discovery of these drugs is costly, time-consuming, and often requires the use of animal models that do not yield results that translate to clinical trials. Due to these shortcomings, researchers seek to develop physiologically relevant in vitro tumor models that more accurately mimic the tumor microenvironment for cheaper and faster high-throughput drug screening. The aim of this research was …

The Santa Clara, 2024-03-01, Santa Clara University

The Santa Clara

No abstract provided.

Finite Element Analysis Of Thermal-Mechanical Instabilities In Nonmetallic Friction Composite Material, Joseph-Shaahu Shaahu

Electronic Theses and Dissertations

Thermal-mechanical instability (TMI) has been a research topic of interest as it focuses a lot on transportation systems. Thermal-mechanical instability was first noticed in railway and experimentally studied with a pin-to-pin or pin-to-surface setup of sliding contact. The topic has been extended into brakes and clutches which are two of the most common sliding systems most susceptible to thermal buckling and thermoelastic instability (TEI), where thermal buckling and thermoelastic instability are two sub-categories of thermal-mechanical instability. Thermal-mechanical instability is an ongoing research to better understand the phenomenon and the limits at which such instability occurs. This work delved into the …

Resurge: Reusable Electrosurgical Handheld Devices Business Plan For Hospitals In East Africa, Kiana Martin

Graduate Theses - Engineering Management

No abstract provided.

Immersive Virtual Reality-Based Learning As A Supplement For Biomedical Engineering Labs: Challenges Faced And Lessons Learned, Ishita Tandon, Vitali Maldonado, Megan Wilkerson, Amanda Walls, Raj R. Rao, Mostafa Elsaadany

Biomedical Engineering Faculty Publications and Presentations

Introduction: Immersive virtual reality (VR) based laboratory demonstrations have been gaining traction in STEM education as they can provide virtual hands-on experience. VR can also facilitate experiential and visual learning and enhanced retention. However, several optimizations of the implementation, in-depth analyses of advantages and trade-offs of the technology, and assessment of receptivity of modern techniques in STEM education are required to ensure better utilization of VR-based labs.

Methods: In this study, we developed VR-based demonstrations for a biomolecular engineering laboratory and assessed their effectiveness using surveys containing free responses and 5-point Likert scale-based questions. Insta360 Pro2 camera and Meta Quest …

Fabrication And Characterization Of Quad-Component Bioinspired Hydrogels To Model Elevated Fibrin Levels In Central Nervous Tissue Scaffolds, Jennifer Steele, Dany J. Munoz-Pinto

Engineering Faculty Research

Multicomponent interpenetrating polymer network (mIPN) hydrogels are promising tissue-engineering scaffolds that could closely resemble key characteristics of native tissues. The mechanical and biochemical properties of mIPNs can be finely controlled to mimic key features of target cellular microenvironments, regulating cell-matrix interactions. In this work, we fabricated hydrogels made of collagen type I (Col I), fibrin, hyaluronic acid (HA), and poly (ethylene glycol) diacrylate (PEGDA) using a network-by-network fabrication approach. With these mIPNs, we aimed to develop a biomaterial platform that supports the in vitro culture of human astrocytes and potentially serves to assess the effects of the abnormal deposition of …

Root And Causes Of Skilled Labor Shortage In Construction Industry: Comprehensive Literature Review, Nicholas Hardy, Carolina Barbosa-Resende, James Kereri, Arash Taghinezhad

The Professional Constructor

The skilled labor shortage is well documented from a historical perspective via studies focusing various construction trades such as carpentry, mechanical, electric and plumbing, and tile setters. Causes of such shortages such as industry image, college as a preferred choice after high school, and construction being a last resort have been investigated extensively. Consequently, possible solutions ranging from amplifying shop classes in high school to intensifying recruiting efforts for union training programs have all been addressed throughout the last 40 years. However, recent studies have focused on identifying the magnitude and reach of the skilled labor gap while limited attention …

An Exploratory Framework For Benchmarking Vehicle Miles Traveled (Vmt) Estimates Associated With University Campuses, Troy Kawahara

Master's Theses

Although vehicle miles traveled (VMT) has become the standard for assessing transportation related impacts in California, some have concerns that many VMT estimates are not properly grounded or informed by real world data, potentially resulting in flawed estimates and impact assessments. This is especially true of special generators, like college and university campuses, which have complex travel patterns distinct from that of the general public. This thesis attempts to resolve a significant disparity observed between two credible VMT estimates for Cal Poly’s campus wide VMT. As part of a campus master planning effort, a VMT estimate was produced in 2019 …

Finite Element Analysis Of The Bearing Component Of Total Ankle Replacement Implants During The Stance Phase Of Gait, Timothy S. Jain

Master's Theses

Total ankle replacement (TAR) implants are an effective option to restore the range of motion of the ankle joint for arthritic patients. An effective tool for analyzing these implants’ mechanical performance and longevity in-silico is finite element analysis (FEA). ABAQUS FEA was used to statically analyze the von Mises stress and contact pressure on the articulating surface of the bearing component in two newly installed fixed-bearing total ankle replacement implants (the Wright Medical INBONE II and the Exactech Vantage). This bearing component rotates on the talar component to induce primary ankle joint motion of plantarflexion and dorsiflexion. The stress response …