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Smart Zoning Control For Air Conditioning Systems, Octavio Gomes Diaz

Mechanical Engineering Theses

Nearly 45% of the energy consumed in residential buildings goes for Heating, Ventilation, and Air Conditioning (HVAC). Typical HVAC systems are mostly controlled by one thermostat that is usually located in the living room. This means that the HVAC system is running without consideration of the thermal conditions in the other rooms (zones), which might be colder (or warmer). Colder zones in the summer indicate that a lot of energy is wasted, and warmer zones mean that the HVAC system can’t produce a good comfort level. Therefore, zoning was introduced into relatively recent HVAC systems. Zoning in HVAC systems uses …

Frameworks For The Techno-Economic Assessment Of Membrane-Based Bioprocessing Platforms, Juan Jose Romero Conde

All Dissertations

This dissertation describes developing and implementing computational frameworks for simulating and optimizing purification processes in the biopharmaceutical industry. The framework performs techno-economic analyses to establish value propositions for new process alternatives, especially membrane technologies. Initially, the focus is developing a framework capable of simulating monoclonal antibody (mAb) capture using membrane and resin media in multi-column chromatography (MCC) platforms for continuous manufacturing. Subsequently, the impact of capture MCC is compared against other intensification strategies in established mAb manufacturing facilities. Finally, the framework application expands to simulate the purification of adeno-associated virus (AAV) vectors for gene therapy.

Chapter 2 details the framework …

Contribution Of Collagen Type I To The Mechanical Properties Of Myocardial Tissues At The Micron Level, Adam Baker

All Dissertations

Collagen is a critical component of the organization and one of the key factors contributing to the mechanical stability of the myocardium. Where cardiomyocytes actuate to contract the heart and deliver blood to the lungs and the entire body, the local collagen network must be able to support the mechanical needs of the heart by enhancing rigidity, reducing the mechanical responsibility of cells, and increasing compliance to add loading capacity during diastole. At an organ-wide level, this has been measured and modeled in many ways. At the tissue level, the mechanical properties have been evaluated using techniques such as bi-axial …

Lab To Leadership: How Do Women College Stem Students’ Classroom Experiences Inform Their Leader Identity Development?, Meredith Mcdevitt

All Dissertations

This dissertation is an exploration of leader identity development and women in science, technology, engineering, and mathematics (STEM) college academic classrooms. While there continues to be research promoting diversity in STEM professions, women remain underrepresented in STEM disciplines, leadership positions, and for this specific study, the college academic classroom. This dissertation represents an opportunity for women in STEM college students to reflect on their experiences in STEM academic spaces and communities, while self-exploring factors that shape their leader identity development. The research utilized a basic qualitative research design to understand the participant’s authentic experiences within the academic environment. Conducting semi-structured …

Exploring The Synthesis Of Biobased And Chemically Recyclable Polysulfone Using Imine Chemistry, Vitasta Jain

All Dissertations

Plastic waste poses a major problem because of the chemical stability of these materials, leading to their accumulation in the environment and the leaching of toxic chemicals during their slow decomposition. Additionally, the use of depleting petroleum reserves for synthesis has made for an unsustainable production and risks due to use of chemicals hazardous to the environment and the individuals exposed to it.

To address these concerns, researchers have explored biobased feedstock and incorporating chemical recycling capabilities for a closed loop, sustainable process. One promising feedstock is lignin with its abundant functional groups that can be modified and utilized to …

Hybrid Physics-Infused Machine Learning Framework For Fault Diagnostics And Prognostics In Cyber-Physical System Of Diesel Engine, Shubhendu Kumar Singh

All Dissertations

Fault diagnosis is required to ensure the safe operation of various equipment and enables real-time monitoring of associated components. As a result, the demand for new cognitive fault diagnosis algorithms is the need of the hour. Existing deep learning algorithms can detect, classify, and isolate faults. Still, most depend solely on data availability and do not incorporate the system's underlying physics into their prediction. Therefore, the results generated by these fault-detecting algorithms sometimes need to make more sense and deliver when tested in actual operating conditions.

Similar to diagnosis, the fault prognosis of diesel engines is paramount in numerous industries. …

Measuring Cannulation Behavior On A Sensorized Simulator: Development, Verification, And Testing Of System Components, Lydia Petersen

All Dissertations

End Stage Kidney Disease (ESKD) is a significant public health burden in the United States. Life-sustaining hemodialysis, required up to three times a week for ESKD patients, necessitates a functioning vascular access. For proper cannulation, cannulators have many factors to consider, including an AVF’s geometry, depth, diameter, and other details. Poor cannulation can lead to infiltration, where the needle punctures the vessel wall. Infiltration occurs in as many as 50% of cannulations, causing complications ranging from hematoma and swelling to delayed treatment or loss of vascular access. This highlights the need for objective, standardized training methods to improve cannulation skills …

Sustainable Waste-To-Bioproducts Engineering Center Laboratory Safety Project, Claudine Mock

All Graduate Reports and Creative Projects, Fall 2023 to Present

Laboratory accidents are common in teaching and research labs; these accidents can be injurious or even fatal. The consequences of each type of laboratory accident are different based on the activities performed and the hazardous materials used in each facility. However, the most common issue related to laboratory accidents is the lack of proper safety measures (e.g., poor handling of hazardous materials, not reporting incidents immediately, etc.). This project aimed to establish and strengthen best practices and procedures to ensure laboratory safety at the Utah State University Sustainable Waste-to-Bioproducts Engineering Center. To achieve this goal, different practices and measures were …

Effect Of Nutrient And Temperature Conditions On The Production Of Microcystins From Cyanobacteria In Pineview Reservoir, Brent G. Jacobson

All Graduate Theses and Dissertations, Fall 2023 to Present

Cyanobacteria, sometimes known as harmful algae, are an aquatic bacteria capable of producing toxic compounds. Cyanobacteria are found worldwide in both saltwater and freshwater environments. Depending on the environment, toxic cyanobacteria species can outcompete other aquatic species, grow in large numbers, and produce these toxic compounds. Further understanding of what environmental conditions promote the production of these harmful bacteria and toxins is needed to protect and inform the public.

In order to understand why cyanobacteria produce toxins in certain environments, samples containing cyanobacteria were taken from a Pineview Reservoir, Utah, and cultured at the Utah State Water Research Laboratory. Cyanobacteria …

Federated Learning In Wireless Networks, Xiang Ma

All Graduate Theses and Dissertations, Fall 2023 to Present

Artificial intelligence (AI) is transitioning from a long development period into reality. Notable instances like AlphaGo, Tesla’s self-driving cars, and the recent innovation of ChatGPT stand as widely recognized exemplars of AI applications. These examples collectively enhance the quality of human life. An increasing number of AI applications are expected to integrate seamlessly into our daily lives, further enriching our experiences.

Although AI has demonstrated remarkable performance, it is accompanied by numerous challenges. At the forefront of AI’s advancement lies machine learning (ML), a cutting-edge technique that acquires knowledge by emulating the human brain’s cognitive processes. Like humans, ML requires …

A Position Allocation Approach To The Battery Electric Bus Charging Problem, Alexander Brown

All Graduate Theses and Dissertations, Fall 2023 to Present

With an increasing adoption of Battery Electric Bus (BEB) fleets, developing a reliable charging schedule is vital to a successful migration from their fossil fuel counterparts. In this work, a BEB charging scheduling framework that considers fixed route schedules, multiple charger types, and battery dynamics is modeled as a Mixed Integer Linear Program (MILP). The MILP is modeled after the Berth Allocation Problem (BAP) in a modified form known as the Position Allocation Problem (PAP). The optimization coordinates BEB charging to ensure that each vehicle remains above a specified charge percentage. The model also minimizes the total number of chargers …

Method Development For The Extraction And Analysis Of Per- And Polyfluoroalkyl Substances (Pfas) In Wastewater And Biosolids, Victoria Krull

All Graduate Theses and Dissertations, Fall 2023 to Present

Per and poly-fluorinated alkyl substances (PFAS) are manufactured chemicals that have water and grease repellant properties and do not readily biodegrade. PFAS are present in many consumer products and end up in waste systems and the environment. Studies have shown that PFAS can have adverse health effects on humans and animals.

There are many challenges to processing and analyzing samples containing PFAS including: adsorption of PFAS to equipment, contamination from equipment containing PFAS, and the high sensitivity needed to analyze for PFAS in the parts per trillion detection range. The United States Environmental Protection Agency (EPA) has been developing methods …

Development Of A High-Throughput Methodology For Vibration-Based Fatigue Tests, Brandon Alexander Furman

All Graduate Theses and Dissertations, Fall 2023 to Present

Global efforts towards the development of additively manufactured materials, biomaterials, metamaterials, self-healing materials, and composites have reached a staggering pace. With new materials being developed on a near-daily basis, it is more important than ever to be able to quickly and precisely quantify their mechanical performance. However, one of the most important mechanical properties, fatigue life, is notoriously time consuming to measure. Consequently, fatigue parameters are often calculated based on small sample sizes, resulting in high uncertainty of the measured parameters. In this dissertation a high-throughput approach to fatigue measurements is developed. This technique allows for multiple samples to accumulate …

Trip Production Models For Persons With Disabilities, Pouyan Saeidian

All Graduate Theses and Dissertations, Fall 2023 to Present

Nearly 13% of the US population consists of people with disabilities, yet finding an equitable and comprehensive approach to meet their travel needs remains a challenge. Our research delves into the mobility patterns of people with disabilities to understand how their daily travel—both the frequency of trips and the distance covered—compares to those without disabilities. We also explore the factors influencing their travel behaviors and how these insights can guide policymakers in improving accessibility and mobility for this community. Utilizing data from the 2022 US National Household Travel Survey, we applied a blend of statistical analysis and machine learning methods. …

Defining Engineering Leadership And Engineering Leadership Skills From The Perspectives Of Abet Leaders And Professional Engineers, Yemisi Victoria Oyewola

All Graduate Theses and Dissertations, Fall 2023 to Present

Leadership within the engineering domain has gained significant recognition in recent years due to calls from the literature, industry, and engineering professional bodies to incorporate leadership training into the engineering curriculum. In response to these calls and despite various approaches that have been implemented by engineering institutions to teach engineering leadership, research indicates that there remains a lack of consensus on the definition of engineering leadership and the specific skills that should be emphasized in the teaching of engineering leadership. Also, there is evidence in the literature that there exists a debate regarding the nature of engineering leadership, with some …

Anomaly Detection On Wind Turbine Blades Using Aerial Imaging, Image Processing, And Deep Learning, Bridger Kohl Altice

All Graduate Theses and Dissertations, Fall 2023 to Present

In reaction to rising global temperatures and carbon dioxide emissions, many countries are looking to use energy sources other than fossil fuels. One such source of energy is wind energy, which can be harvested by wind turbines. By rotating at high speeds, the blades of these large turbines are able to convert wind energy to kinetic energy, which is then converted to electricity usable by the power grid. Traditional methods for inspecting these turbines for damages are expensive, unsafe, and susceptible to human error. These turbines are so tall and so large that inspectors run the risk of falling from …

Development Of Electric Vehicle Charging Station Microgrid With Simulation Modelling, Tenzin Lhaden

Open Access Theses & Dissertations

The rapid adoption of electric vehicles (EVs) necessitates innovative solutions to overcome challenges in energy management, sustainability, and grid reliance. This research develops a hybrid simulation model for EV charging stations, integrating renewable energy sources, such as solar photovoltaic (PV) systems, with energy storage systems (ESS). Leveraging discrete-event simulation (DES) and agent-based modeling (ABM) in AnyLogic, the model offers a comprehensive analysis of charging station operations, incorporating stochastic EV arrivals, dynamic energy allocation, and user-defined customization.Key contributions include the development of hybrid simulation model integrating solar PV, energy storage, and energy management systems (EMS) that dynamically optimizes energy distribution from …

Development Of 3d Human Cardiovascular And Cancer Tissue Model Within A Self-Driven Microfluidic Platform For Preclinical Drug Screening, Aibhlin Alexis Esparza

Open Access Theses & Dissertations

According to the American Heart Association and World Health Organization, cardiovascular diseases (CVDs) are the leading cause of death worldwide. Monolayer cell culture (2D) and animal models are conventional methods to study CVDs, however, they limit researcherâ??s ability to simulate the human cardiovascular cellular microenvironments and accurate predication of pharmaceutical drug responses. Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs), biomaterials, and microfluidic technologies can be combined to create a controlled, reproducible 3D platform to study physiologically-relevant cellular responses to biochemical and physical changes in the microenvironment. My dissertation work demonstrates the development of novel self-driven microfluidic devices designed with …

Using Causal Inference To Understand Public Perception Towards Electric Vehicle Adoption, Jesus Alejandro Gutierrez Araiza

Open Access Theses & Dissertations

Why despite all efforts to promote Electric Vehicles (EVs) as an alternative transportation method through strategies such as tax credits on unit purchasing or long-term environmental benefits communication, its market penetration has not reached the expected goals in the United States? Even though there have been important advancements in the EV technical perspective and financial EV purchasing incentives, the final EV customers still face barriers on their scenarios that do not allow them to purchase this type of contemporary transportation means. Not understanding their local barriers could be a mistake that could reduce EVA expectations in the country and keep, …

Integrating Machine Learning And Simulation For Resource Planning Of Hospital Systems Based On Predicted Length Of Stay, S M Atikur Rahman

Open Access Theses & Dissertations

Recently Hospital Systems faced a high invasion of patients generated by several events such as health crisis related epidemic (COVID, FLU) or seasonal flows. Hence, managing hospital bed availability and efficiency with proper care is obligatory for addressing the challenges associated with the overburden of patients. However, the Length of stay (LOS) is often increased due to the high patient influx and overcrowding problem occurs within the Hospital. It resolves these issues, it is essential for hospital authority to predict the Patients LOS which is the crucial indicator for the use of medical resources (allocation, utilization of providers and resource) …

Home Care Work Of Caregivers For Mexican American Adults With Dementia: A Culturally Informed Model Integrating Work System Analyses And Health Disparities Research Framework, Laura Cristina Tovar Felix

Open Access Theses & Dissertations

Dementia is an umbrella term for different diseases such as Alzheimer's, vascular dementia, Lewy body, frontotemporal, and mixed dementias. Dementia is caused by a variety of diseases that cause damage to brain cells interfering with the ability of brain cells to communicate between each other. Dementia is associated with different types of brain cell damage in a specific region of the brain (What Is Dementia?, 2024).Dementia affects 55 million people worldwide, where the most affected population is the low-income and the middle-income countries. (Greenblat, 2023). Every 20 years the number almost double, and by 2039 is estimated to reach 78 …

Penetration Thresholds Of Porcine Limbs For Low Sectional Density Projectiles In High-Rate Impact, Joseph Lesueur, Jared Michael Koser, Carolyn E. Hampton, Michael Kleinberger, Frank A. Pintar

Biomedical Engineering Faculty Research and Publications

Introduction

With similar prevalence to injuries from fires, stings, and natural disasters, soft tissue injuries may occur from fireworks, industrial accidents, or other explosives. Surgeons are less familiar with treating high-velocity penetration from small debris, which may increase the chance of infection and subsequent fatality. Penetration risk curves have been developed to predict V₅₀, the velocity with 50% probability of penetration, for various sized projectiles. However, there has been limited research using nonmetallic materials to achieve lower density projectiles less than 1 g cm−2, such as sand or rocks.

Material and Methods

To emulate the size and density …

Synthesis Of Nanoparticles And Their Applications In Power Module Packaging And Organic Electronics, Xinsong Zhang

Graduate Theses and Dissertations

Nanoparticles can greatly change the properties of regular materials due to their special structures. In this research nanoparticles, such as silver nanowires, silver nanospheres and expanded graphite, are used in interconnection materials for power module packaging, and in conductive films for organic electronics. Silver nanowires synthesized by polyol synthesis, are used as fillers in micron silver paste. The electrical and mechanical properties of the sintered hybrid silver paste are investigated and compared with those of micron silver paste. The composites of silver nanospheres and expanded graphite are mixed with PEDOT:PSS solutions in 5 different weight ratio. The electrical and optical …

Exploring Telehealth Utilization Through Data Analytics, Statistical Analyses, And Machine Learning Techniques, Aysenur Betul Cengil

Graduate Theses and Dissertations

This dissertation investigates the utilization of telehealth services, initially focusing on the Arkansas healthcare system and then extending the analysis nationwide. It aims to understand the factors influencing telehealth adoption and its impact on healthcare delivery. After examining telehealth utilization in Arkansas from 2018 to 2022, the research utilizes a comprehensive dataset from Epic Cosmos, which includes a wide range of patient and visit data from multiple healthcare facilities across the United States from 2018 to 2023. This timeframe allows for a detailed analysis of telehealth trends before, during, and after the COVID-19 pandemic. In Chapter 2, we analyze key …

Development Of A High-Throughput Screening Platform To Profile Gene Delivery And Transcriptional Control In Macrophages, Alexis Ivy

Graduate Theses and Dissertations

Macrophages are an important cell type in the body responsible for orchestrating the inflammatory response and return to homeostasis. Macrophages are often implicated in a multitude of disease pathologies including delayed wound healing, excessive fibrosis, autoimmune disease, and immunosuppression within the tumor microenvironment. Although macrophages have been targeted for therapeutic applications, success in utilizing them has remained elusive due to their relative ease of phenotype switching between inflammatory and anti-inflammatory. The challenge that remains is developing clinically relevant delivery vehicles that can target macrophages without causing a phenotypic switch counter-productive to the desired response. This is especially important when targeting …

Application Of Electrical Impedance Tomography To Cementitious Composites, Hugo Zazueta

Theses and Dissertations

This thesis explores the feasibility of using Electrical Impedance Tomography (EIT) for detecting damage in cementitious composites. Cementitious composites, such as concrete and cement mortar, are insulating; any conductive properties arise from the moisture within their pores and capillary structures. The proposed concept herein is that formed internal damages in cementitious composites consequently alter their pore and capillary structure, which can then be detected through EIT imaging. To construct tomographic images, the Gaussian Newton (GN) reconstruction algorithm, enhanced with priors, was employed. The results were then compared across different reconstruction processes. Cylindrical cement pastes and cement mortar samples were prepared, …

A Real-Time Iot-Based Data Acquisition And Monitoring System For Photovoltaic Applications, Adam Barbosa, Hamza Mubarak, Fazel Mohammadi, Mohammad J. Sanjari, Mehrdad Saif

Electrical & Computer Engineering and Computer Science Faculty Publications

The transition to low-carbon energy systems, driven by climate change and fossil fuel scarcity, highlights technologies, such as Photovoltaic (PV) technology, for sustainable energy generation. This paper focuses on enhancing the efficiency of PV monitoring systems by leveraging Internet of Things (IoT) technology for accurate and real-time monitoring of essential parameters, such as voltage, current, and output power. Significant gaps in cost-effective and reliable IoT integration for PV monitoring are addressed, with an emphasis on predictive modeling. In this regard, a low-cost real-time IoT-based data acquisition and monitoring system for PV systems, as a proof of concept for future endeavors …

Nanoparticle-Based Approaches To Brain Injury And Studies For Improved Detectability Toward Better Delivery Characterization, Hunter A. Miller

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The clinical translation of nanoparticle (NP) therapeutics for brain injury has been slow despite preclinical promise. The causes of disconnect between preclinical and clinical outcomes is multifactorial, but insufficient delivery is noteworthy. Preclinical delivery characterization often lacks, obscuring mechanisms of failure, slowing development. Multimodal imaging is a promising strategy to improve delivery characterization, combining the strengths of various modalities. Magnetic resonance imaging (MRI) and luminescence imaging are a suitable combination for multimodal imaging, expanding the spatial and temporal resolution of either alone, but further material development is needed to enhance detectability. One problem is the interference of cellular autofluorescence in …

The Role Of Kinases Signaling In Organogenesis, Fatemeh Nasehi

All Dissertations

Kinases are crucial regulators of organ development and differentiation. This thesis investi- gates the roles of TAK1, TGFbeta-Activate Kinase 1 (TAK1/Map3K7), and Akt3 kinases in skeletal, cardiac muscle, and cartilage. TAK1 is pivotal for the differentiation of various organ systems, including sinoatrial node and cartilage, and is responsible for phosphorylat- ing a diverse array of downstream kinases. We identified several novel proteins, including phospho-Akts, that are upregulated in response to TAK1 activation. We discovered severe Dilated Cardiomyopathy (DCM) and cartilage defects in Akt3 mutant mice. Although this mouse mutant has been studied for over two decades, we are the first …

Identification And Validation Of A Measurement Of Emergency Physician Workload During End Of Shift Patient Handoffs, Steven Foster

All Dissertations

Recent increases in emergency physician (EP) workload have been identified as contributors to increased EP burnout, increased staff attrition, decreased patient safety, and increased patient admission rates. Patient handoffs have been extensively researched as critical points in patient care, with existing research primarily focusing on communication errors and interventions designed to standardize handoff communication protocols.

While end of shift handoffs in hospital emergency departments (EDs) intuitively represent a transfer of patient caseload from an outgoing EP to an incoming EP, there is a fundamental lack of literature examining how such handoffs contribute to EP workload, and a similar lack of …