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Articles 4831 - 4860 of 41154
Full-Text Articles in Entire DC Network
08.05.2024 Orsp Connect, Liz Williamson
08.05.2024 Orsp Connect, Liz Williamson
ORED Newsletter
Dr. John C. Higginbotham, Federal Demonstration Partnership (FDP), COPE (Clinic for Outreach and Personal Enrichment)
08.05.2024 Ored Connect, Liz Williamson
08.05.2024 Ored Connect, Liz Williamson
ORED Newsletter
Meet the new Vice Chancellor for Research and Economic Development, Dr. John C. Higginbotham.
FDP Meeting Summaries link
Collaborate with COPE
Vibration Analysis And Condition Monitoring For Cement Mill (Case Of Hamma Bouziane-Constantine Cement Plant), Linda Bouyaya
Vibration Analysis And Condition Monitoring For Cement Mill (Case Of Hamma Bouziane-Constantine Cement Plant), Linda Bouyaya
Emirates Journal for Engineering Research
Monitoring and diagnosing damage in dynamic machinery is a growing area of interest in the cement industry. Indeed, industrial equipment is disrupted throughout its operation by malfunctions; especially in old age; which reduces their operating costs and availability. Therefore, the detection and identification of faults in industrial systems - diagnosis - is of capital importance for their operation and a major challenge for modern industry. Among the most used diagnostic techniques, we find spectral analysis, a condition-based maintenance tool, which is used to study the vibration signals of dynamic machines.
In this context, the objective of this work is the …
Design Of A Semi-Continuous Bio-Oil Upgradation Process Using Iron/Bone-Char Catalysts, Kelli Thomas
Design Of A Semi-Continuous Bio-Oil Upgradation Process Using Iron/Bone-Char Catalysts, Kelli Thomas
Graduate Theses & Non-Theses
- 07Bio-oil is a pyrolysis byproduct that consists of heavily oxygenated organic fractions with low caloric values. There are very few industrial-sized facilities that can process bio-oil into useful hydrocarbons comparable to petroleum products. With the increase in biochar production for remediation efforts and forest clean-up, there is a demand for portable, small-scale refineries that do not require extensive process and safety equipment to convert byproducts into usable fuels. Refining bio-oil via atmospheric hydrodeoxygenation (HDO), the removal of the oxygenated functional groups under an unpressurized hydrogenated atmosphere, results in the upgradation of the heavy hydrocarbons within the bio-oil. This process is …
Process Intensification For Carbon Sequestration By Resonant Vibratory Mixing, Amirhosein Riahi
Process Intensification For Carbon Sequestration By Resonant Vibratory Mixing, Amirhosein Riahi
Graduate Theses & Non-Theses
Due to the excessive consumption of fossil fuels, which leads to significant greenhouse gas emissions and rapid climate change, it is crucial to develop various Carbon Capture and Sequestration strategies. CO2 sequestration in solid, porous adsorbents like low-cost biochar emerges as a promising method to achieve this goal. However, slow adsorption kinetics are one of the issues that limit the widespread use of biochar. While the characteristics of biochar are important and impact CO2 adsorption, the conditions under which adsorption occurs are equally critical.
In this work, a novel process intensification strategy, namely Low-Frequency High Amplitude resonant vibratory …
A Methodology For Evaluating And Comparing Unmanned Inspection Platforms In Underground And Indoor Environments, Sydney Shockley
A Methodology For Evaluating And Comparing Unmanned Inspection Platforms In Underground And Indoor Environments, Sydney Shockley
Graduate Theses & Non-Theses
This report summarizes a research project focused on development of a methodology for evaluating the performance of various unmanned aerial vehicles (UAVs, commonly referred to as drones) and robotic platforms in GPS-denied environments, highlighting a clear stratification based on technological sophistication and design intent. A series of flight trials were designed and implemented in various environments including indoor spaces with various geometries and obstacles, and an underground mine. These trials examined signal range from the unmanned platform to the controller, the ability to navigate through confined spaces and obstacles, the overall ease-of-use and responsiveness of controls, as well as specialized …
Radiation-Tolerant Thin-Film Reference Electrodes And Potentiometric Sensors, Bingyuan Zhao, Alexander Wei
Radiation-Tolerant Thin-Film Reference Electrodes And Potentiometric Sensors, Bingyuan Zhao, Alexander Wei
Department of Chemistry Faculty Publications
The integration of electronic sensors into single-use systems for bioprocessing is challenged by their sensitivity to sterilizing γ-irradiation. This challenge also applies to reference electrodes (REs), whose potentials may be destabilized upon ionization and drift over time. Here we evaluate the performance of thin-film Ag/AgCl REs over a two-month window following γ-ray sterilization using a 60Co source. γ-REs display a characteristic voltage decay function ascribed to the dissipation of radiation-induced charge defects, and exhibit long-term potentiometric stability when stored in phosphate-buffered saline (PBS) with a 95% confidence interval of 4 mV over 60 days. γ-REs have a mean insensitivity (inertness) …
Development And Structural Origin Of Stretchable Semiconducting Polymers And Composites, Yunfei Wang
Development And Structural Origin Of Stretchable Semiconducting Polymers And Composites, Yunfei Wang
Dissertations
Stretchable semiconductors are pivotal in advancing wearable and implantable electronics, with those boasting both high stretchability and self-healing capabilities being especially significant for a myriad of wearable applications. In this dissertation, we developed an extremely soft, highly stretchable, and self-healing elastomer based on H-bonding crosslinked amide-functionalized polyisobutylene (PIB-amide). When blended with a high-performance conjugated diketopyrrolopyrrole (DPP-T) polymer, the composite exhibits unprecedented stretchability, exceptionally low elastic modulus, and an innate ability to self-heal at room temperature.
The morphology of conjugated polymer/elastomer semiconducting composites have significant impacts on electrical and mechanical properties Further investigations focused on manipulating the phase separation size in …
Evaluation Of The Alveolar Crest And Cemento-Enamel Junction In Periodontitis Using Object Detection On Periapical Radiographs, Tai Jung Lin, Yi Cheng Mao, Yuan Jin Lin, Chin Hao Liang, Yi Qing He, Yun Chen Hsu, Shih Lun Chen, Tsung Yi Chen, Chiung An Chen, Kuo Chen Li, Patricia Angela R. Abu
Evaluation Of The Alveolar Crest And Cemento-Enamel Junction In Periodontitis Using Object Detection On Periapical Radiographs, Tai Jung Lin, Yi Cheng Mao, Yuan Jin Lin, Chin Hao Liang, Yi Qing He, Yun Chen Hsu, Shih Lun Chen, Tsung Yi Chen, Chiung An Chen, Kuo Chen Li, Patricia Angela R. Abu
Ateneo Laboratory for Intelligent Visual Environments
The severity of periodontitis can be analyzed by calculating the loss of alveolar crest (ALC) level and the level of bone loss between the tooth’s bone and the cemento-enamel junction (CEJ). However, dentists need to manually mark symptoms on periapical radiographs (PAs) to assess bone loss, a process that is both time-consuming and prone to errors. This study proposes the following new method that contributes to the evaluation of disease and reduces errors. Firstly, innovative periodontitis image enhancement methods are employed to improve PA image quality. Subsequently, single teeth can be accurately extracted from PA images by object detection with …
Thrombogenicity Of Biodegradable Metals, D. E.J. Anderson, H. H. Le, H. Vu, J. Johnson, J. E. Aslan, J. Goldman, M. T. Hinds
Thrombogenicity Of Biodegradable Metals, D. E.J. Anderson, H. H. Le, H. Vu, J. Johnson, J. E. Aslan, J. Goldman, M. T. Hinds
Michigan Tech Publications
Biodegradable metals offer a promising means to ameliorate many of the long-term risks associated with vascular devices made of conventional biostable stent metals. While numerous biodegradable metal alloys have been developed and characterized in animal models, knowledge of their blood reactivity and thrombogenicity remains unknown. Metal hemocompatibility is particularly valuable because current generation drug-eluting stents pose a significant long-term thrombosis risk. In this study, four pure metals, widely used as degradable base materials (Fe, Zn, Mg, and Mo), and three alloys commonly used in cardiovascular devices [NiTi, CoCr, and stainless steel (SS)] were evaluated. This work examined how each of …
Application Of Agent-Based Simulation And Game Theory In Evaluating Implementation Of Whole Genome Sequencing In Treating Lung Cancer, Fateme Ghalenoei
Application Of Agent-Based Simulation And Game Theory In Evaluating Implementation Of Whole Genome Sequencing In Treating Lung Cancer, Fateme Ghalenoei
Master's Theses
Cancer, particularly lung cancer, presents significant diagnostic and economic challenges globally. Timely diagnosis and cost management play pivotal roles in treatment success. A biomarker is any measurable molecule in blood, bodily fluids, or tissues, indicating the potential presence of an abnormal bodily process, condition, or disease. Biomarker testing is a laboratory test in oncology that is used in the selection of targeted cancer treatments and to help avoid ineffective treatments. Whole Genome Sequencing (WGS), is a biomarker test which while more comprehensive, comes at a higher cost. This study proposes an agent-based simulation model within a game-theoretic framework to examine …
Unrefined And Milled Ilmenite As A Cost-Effective Photocatalyst For Uv-Assisted Destruction And Mineralization Of Pfas, Eustace Y. Fernando, Zhiming Zhang
Unrefined And Milled Ilmenite As A Cost-Effective Photocatalyst For Uv-Assisted Destruction And Mineralization Of Pfas, Eustace Y. Fernando, Zhiming Zhang
Henry M. Rowan College of Engineering Departmental Research
Per- and polyfluoroalkyl substances (PFAS) are fluorinated and refractory pollutants that are ubiquitous in industrial wastewater. Photocatalytic destruction of such pollutants with catalysts such as TiO2 and ZnO is an attractive avenue for removal of PFAS, but refined forms of such photocatalysts are expensive. This study, for the first time, utilized milled unrefined raw mineral ilmenite, coupled to UV-C irradiation to achieve mineralization of the two model PFAS compounds perfluorooctanoic acid (PFOA) and perfluoro octane sulfonic acid (PFOS). Results obtained using a bench-scale photocatalytic reactor system demonstrated rapid removal kinetics of PFAS compounds (>90% removal in less than 10 …
Impact Of Equipment Type On Measured Particle Size Of Civil Engineering Materials, Tanner Turben
Impact Of Equipment Type On Measured Particle Size Of Civil Engineering Materials, Tanner Turben
Graduate Theses and Dissertations
Particle size analysis (PSA) captures the size distribution of fine-grained or emulsified materials with particles generally smaller than 1000 microns. Asphalt emulsions and many other civil engineering materials do not leverage PSA for material specifications or acceptance despite the insight into material performance and quality gained through understanding the particle size. The objectives of this study are to compare PSA measurement principles by testing 13 civil engineering materials by laser diffraction, Coulter counter, and microscopy and to develop a draft standard procedure for asphalt emulsion PSA. Asphalt emulsions, cementitious materials, sands, clays, and biological samples were selected to represent a …
Real-Time Barge Detection Using Traffic Cameras And Deep Learning On Inland Waterways, Geoffery Eyram Agorku
Real-Time Barge Detection Using Traffic Cameras And Deep Learning On Inland Waterways, Geoffery Eyram Agorku
Graduate Theses and Dissertations
Inland waterways are critical for freight movement, but limited means exist for monitoring their performance and usage by freight-carrying vessels, e.g., barges. While methods to track vessels, e.g., tug and tow boats, are publicly available through Automatic Identification Systems (AIS), ways to track freight tonnages and commodity flows carried on barges along these critical marine highways are non-existent, especially in real-time settings. This paper develops a method to detect barge traffic on inland waterways using existing traffic cameras with opportune viewing angles. Deep learning models, specifically, You Only Look Once (YOLO), Single Shot MultiBox Detector (SSD), and EfficientDet are employed. …
Epidural Stimulation For Urogenital Dysfunction In The Spinal Cord Injured Rat., Natasha Lorraine Wilkins
Epidural Stimulation For Urogenital Dysfunction In The Spinal Cord Injured Rat., Natasha Lorraine Wilkins
Electronic Theses and Dissertations
Spinal cord injury (SCI) is a devastating, life changing event that greatly impacts quality of life. SCI can have body-wide, multi-system consequences including dysfunction within the urogenital system. Challenges with the urinary system include urinary incontinence, urine retention, and detrusor-sphincter dyssynergia all of which require maintenance through the regular use of catheters. Sexual dysfunction in men, who comprise nearly 80% of the SCI population, includes erectile dysfunction, anejaculation, retrograde ejaculation, poor expulsive force during ejaculation, and poor sperm quality. The treatment for sexual function in SCI men is focused more on fertility through the collection of sperm for insemination procedures …
Adaptive Robot Collaboration Using Robotic Skin And Motion Similarity., Jordan Dowdy
Adaptive Robot Collaboration Using Robotic Skin And Motion Similarity., Jordan Dowdy
Electronic Theses and Dissertations
An essential part of robotics research is human-robot collaboration, which enables the use of current and new robots in everyday life and the workforce. This research applies to both parts of human-robot collaboration: physical human-robot interaction (pHRI), as well as non-physical human-robot interaction. The physical interaction uses tactile sensors and a Neuroadaptive Controller (NAC) to allow for the guidance of a robotic arm and its end-effector. The non-physical interaction uses a novel motion similarity metric, the Cartesian Segment Online Dynamic Time-Warping (SODTW), to allow a robot to better adapt to the speed of the user performing the motion during imitation …
Meteorological Data Mining And Synthesis For Supplementing On-Site Data For Regulatory Compliance, Ben Sonpon, Shoaib Usman, Joseph Smith, Sarah Kovaleski, Jason Wibbenmeyer
Meteorological Data Mining And Synthesis For Supplementing On-Site Data For Regulatory Compliance, Ben Sonpon, Shoaib Usman, Joseph Smith, Sarah Kovaleski, Jason Wibbenmeyer
Nuclear Engineering and Radiation Science Faculty Research & Creative Works
Many regulatory requirements add significant delay in the licensing of new nuclear power stations. One area of particular interest is the environmental impact of potential atmospheric release. the purpose of this research is to demonstrate effectiveness of meteorological data mining and synthesis from offsite locations to reduce need for onsite data, hence allowing rapid licensing. the automated procedures tested for data mining and extraction of meteorological data from multiple offsite sources and the data analytic tool developed for data fusion are presented here. Three important meteorological parameters from regulatory compliance are considered for this analysis: wind velocity, wind direction, and …
Exploring Healthcare Chatbot Information Presentation: Applying Hierarchical Bayesian Regression And Inductive Thematic Analysis In A Mixed Methods Study, Samuel Nelson Koscelny
Exploring Healthcare Chatbot Information Presentation: Applying Hierarchical Bayesian Regression And Inductive Thematic Analysis In A Mixed Methods Study, Samuel Nelson Koscelny
All Theses
High blood pressure, also known as hypertension, significantly increases the risk of heart disease and stroke, which are leading causes of death in the United States. While contributing to over 691,000 deaths in 2021 alone in the United States (U.S.), it also imposes immense economic burden on the healthcare system, costing approximately $131 billion annually. One way to address this issue is for increased self-care behaviors and medication adherence, both of which require sufficient health literacy. Despite the importance of health literacy, 90% of U.S. adults struggle with health-related subjects. Overcoming the issues associated with health literacy requires addressing the …
A Benchtop Analysis Of Pressure Offloading Associated With Custom Socket Inlays In Transtibial Prostheses, Sarah G. Hill
A Benchtop Analysis Of Pressure Offloading Associated With Custom Socket Inlays In Transtibial Prostheses, Sarah G. Hill
All Theses
Approximately 78% of people with lower limb amputations are dissatisfied with the comfort of their prostheses (Quintero-Quiroz & Perez 2019). In the case of lower limb amputations, the residual limb tissue bears far more weight than it was before the amputation. The pressure put on the soft tissue of the residual limb causes discomfort (Brown et al. 2021). In previous work, custom inlays were created, which fit inside the prosthesis and offload pressure, with the goal of helping to increase the comfort and satisfaction of the prosthesis user (Brown et al. 2021). In this project, a benchtop prosthetic socket loading …
Introduction To Neuroengineering, Mercedes Terry, Abigail Tubbs, Blair Dupre, Brandon Fugger, Enrique Alvarez Vazquez
Introduction To Neuroengineering, Mercedes Terry, Abigail Tubbs, Blair Dupre, Brandon Fugger, Enrique Alvarez Vazquez
Open Educational Resources
"Introduction to Neuroengineering" serves as a comprehensive guide to the fast evolving field at the intersection of neuroscience, engineering, and technology. This book covers foundational concepts like neuron structure, action potentials, and neural modeling, moving through advanced topics like brain-computer interfaces (BCIs), neurostimulation, and imaging technologies (EEG, MEG, fMRI). Each chapter combines theory with practical exercises and lab examples, accessible through a GitHub repository to enhance hands-on learning. Aimed at students, educators, and professionals, this resource offers a foundation and inspiration for innovation in neuroengineering, promoting ongoing exploration in this impactful field.
Transforming Construction? Evaluation Of The State Of Structural 3d Concrete Printing In Research And Practice, Alireza Hasani, Sattar Dorafshan
Transforming Construction? Evaluation Of The State Of Structural 3d Concrete Printing In Research And Practice, Alireza Hasani, Sattar Dorafshan
Civil Engineering Faculty Publications
Additive manufacturing in construction has witnessed exponential growth over the recent years. In this paper, advancements in 3D Concrete Printing (3DCP) in additive construction are explored. The authors synthesize the states of research and practice of 3DCP technology for construction through an extensive examination of 137 projects and various publications. Insights are provided into the key factors influencing 3DCP structural performance. The technology is shown to be advantageous, although with varying benefits observed in different cases, including but not limited to reduced cost, labor requirements, material, and construction time. Nevertheless, challenges, such as limited control over the quality, unexplored long-term …
Engineering The Properties Of Magnesium Aluminate Spinel Through Solid State Solutions, Robin Conner
Engineering The Properties Of Magnesium Aluminate Spinel Through Solid State Solutions, Robin Conner
All Theses
Magnesium aluminate spinel solid state solutions were prepared via the coprecipitation method and calcined in air at 900 °C for 2 h. The manipulation of magnesium aluminate spinel’s microstructure through the formation of solid state solutions with zinc and gadolinium substituting for magnesium was investigated. X-ray diffraction (XRD) and attenuated total reflectance Fourier transform infrared spectroscopy (ATR FTIR) confirmed the formation of a single cubic crystalline phase. The luminescence properties were investigated by radioluminescence (RL) under X-ray excitation and thermoluminescence (TL) measurements. In the case of zinc, all concentrations of the solid state solutions showed similar luminescence with bands at …
Trust: The Inertia Taxonomy Of Trust And Learning Outcomes Of Trust Building Exercises, Ann B. Lyons
Trust: The Inertia Taxonomy Of Trust And Learning Outcomes Of Trust Building Exercises, Ann B. Lyons
All Theses
This study investigates United States construction professionals’ view of trust in the workplace. In particular the focus is on building trust through trust building exercises. In order to accomplish this, a literature review was conducted focusing on trust in the worldwide construction industry. This was followed by interviews with US construction professionals who focus on team building. These interviews informed a survey sent to a wide variety of US construction professionals. The survey had two sections of content questions, 1. view of trust indicators and 2. perception of trust building exercises. Finally, experts in the field of construction team building …
Extraction Of Neutron-Gamma Irradiated Diffusion Pump Oils, Cooper L. Tillman
Extraction Of Neutron-Gamma Irradiated Diffusion Pump Oils, Cooper L. Tillman
All Theses
This work successfully demonstrates solvent extraction methods for separation of oil from the by-products when two commercially available vacuum pump oils were exposed to an intense neutron and gamma-ray radiation environment. Nuclear fusion power at a commercial scale has accelerated the need for radiation resistant vacuum technology, such as oil-based diffusion pumps. Polyphenyl ether and aromatic silicone oils were irradiated at the Rhode Island Nuclear Science Center (RINSC) up to MGy absorbed doses with neutron and gamma-ray radiation. Solvent extractions were performed using hexane and isopropanol to characterize the oil extraction as a function of total absorbed dose. The by-products …
Hydrogen Isotope Exchange On Diffusion Pump Oils, Carson G. Allen
Hydrogen Isotope Exchange On Diffusion Pump Oils, Carson G. Allen
All Theses
The extent of isotopic exchange of deuterium and tritium with protium atoms in hydrocarbon pump oil was investigated as a means to quantify the chemical stability of a mineral oil, a silicone oil, and a polyphenyl ether oil as candidates for implementation in a diffusion pump. In its target application at a fusion power plant, a chemically stable and radiation hard oil offers substantial reductions in tritium inventory, electrical consumption, and operational pump expenses over alternate solutions for vacuum induction. Select oils were introduced to deuterium and tritium isotopes in a high temperature environment, analogous to an operating vacuum pump. …
Dynamic Site Characterization For Los Alamos National Laboratory: Topographic Amplification Array Studies And Deep Shear Wave Velocity Profiling Using Masw And Mam Surface Wave Methods, Kyle S. Cannon
All Graduate Theses and Dissertations, Fall 2023 to Present
An assessment of seismic hazard must be performed for any critical structures designed or built in seismically active regions, where critical structures are defined by ASCE as those that, if damaged excessively, could pose a threat to national security, the economy, or public health, safety, and welfare. This is done, in part, through a probabilistic seismic hazard analysis (PSHA) and incorporated site response analysis (SRA). One of the many pieces of information needed to perform a PSHA and an incorporated SRA is the shear wave velocity structure of the site. Additionally, if there are significant topographic features at the site …
Investigating The Detection And Transport Of Low Molecular Weight Species To Better Understand Their Impact On Disease Pathology And Treatment, Haley Michelle Duncan
Investigating The Detection And Transport Of Low Molecular Weight Species To Better Understand Their Impact On Disease Pathology And Treatment, Haley Michelle Duncan
Graduate Theses and Dissertations
Due to the drastic differences in the projects involved, this dissertation will be split into two sections: Alzheimer’s disease and chronic kidney disease. Each chapter will contain an introduction, materials and methods section, results and discussion, conclusions, and works cited section. The Alzheimer’s disease chapter will also have a supplemental figures section containing the polyacrylamide gels that were silver stained and quantified via ImageJ. The presence of elevated levels of amyloid beta oligomeric species in the brain has been related to the pathology of Alzheimer’s disease. As these oligomeric species are transient in nature, their kinetics pose a challenge to …
Feasibility Study For The Application Of A Solar Powered Absorption Chilling System For Cooling Poultry Houses In Northwest Arkansas, Matthew James Kelly
Feasibility Study For The Application Of A Solar Powered Absorption Chilling System For Cooling Poultry Houses In Northwest Arkansas, Matthew James Kelly
Graduate Theses and Dissertations
This paper investigates the economic feasibility of utilizing a solar-powered absorption chiller to provide cooling for poultry houses in northwest Arkansas. An existing thermodynamic model of a poultry house was modified to account for cooling. A simulation was performed using actual weather data from Fayetteville, Arkansas for 26 flocks of broilers at four cooling capacities for the 2020, 2021, and 2022 calendar years. Based on the simulation, the savings from reduced electricity use for ventilation and the cost of the required absorption chiller and solar thermal array for an 8-house farm were calculated. While providing cooling was found to reduce …
Optimization Of And Mechanistic Insights Into Photocatalytic And Non-Thermal Plasma Degradation Of Organic Pollutants For Sustainable Wastewater Treatment, Yiting Xiao
Graduate Theses and Dissertations
Water pollution by organic pollutants poses a significant environmental threat, necessitating the development of advanced treatment technologies to ensure sustainable and efficient remediation. This dissertation explored innovative approaches to enhance the degradation of organic pollutants through the integration of photocatalytic and plasma-assisted systems, with a focus on optimizing these processes using methodologies ranging from response surface methodology (RSM) to advanced machine learning techniques. The first part of the dissertation investigated the degradation of organic pollutants in flocculated liquid digestate using photocatalytic titanate nanofibers (TNFs) synthesized via a hydrothermal method. This study represents the first application of TNFs, with a bandgap …
Development Of An Egg-Specific Mass Spectrometry Targeted Method For Processed Food Matrices, Liyun Zhang
Development Of An Egg-Specific Mass Spectrometry Targeted Method For Processed Food Matrices, Liyun Zhang
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
Egg is a major food allergen in the United States, causing symptoms from mild reactions to severe anaphylaxis. An egg-free diet remains the only management approach for egg allergy. Therefore, individuals and families living with egg allergies rely heavily on allergen statements on packaged food products for informed food choices. Currently, no labeling regulations exist for unintentionally introduced allergens, posing risks to consumers with egg allergies. Therefore, it is critical to have an accurate and reliable detection method in allergen control and management to determine the concentration of total protein from allergenic food sources. Traditional enzyme-linked immunosorbent assays are routinely …