Digital Commons Network^™

Biomarker Identification For Prostate Cancer Using An Efficient Feature Selection Algorithm, Vamsi Krishnam Raju Mantena

Electrical & Computer Engineering Theses & Dissertations

In recent years, there has been an increased interest in using protein mass spectrometry to identify biomarkers that discriminate diseased from healthy individuals. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathological processes, or pharmacological responses to a therapeutic intervention. Identifying biomarkers will be an important step towards disease characterization and patient management. One challenge of biomarker identification is how to handle the high dimensional mass spectral data. In this thesis, we applied an efficient feature selection algorithm to mass spectrometry data obtained from prostate tissue samples to identify prostate …

Education Enhancement Using Visualization And Simulation Tools For Basic Circuit Theory Concepts, Jariwala Rajvi Prakashchandra

Electrical & Computer Engineering Theses & Dissertations

New generation web-technologies and supporting development tools have prompted opportunities for developing new methods of teaching and learning. Web-based visualization and simulation modules developed for ODU's ECE201 Circuit Theory course are presented in this thesis. Visualization and simulation methodology is used to make learning process more interactive and effective. Macromedia FLASH software, which has the extensive graphical animation capabilities, is used to develop visualization modules. Lab VIEW is a leading graphical development tool for science and engineering with a built-in functionality for simulation, data acquisition, instrument control, measurement analysis and data presentation. These capabilities are utilized to develop web-based simulation …

Ala Spotlight Series V.2, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

No abstract provided.

Hand-Held Flyback Driven Coaxial Dielectric Barrier Discharge: Development And Characterization, Victor J. Law, Vladimir Milosavljevic, Neil O’Connor, James F. Lalor, Steven Daniels

Articles

The development of a handheld single and triple chamber atmospheric pressure coaxial dielectric barrier discharge driven by Flyback circuitry for helium and argon discharges is described. The Flyback uses external metal-oxide-semiconductor field-effect transistor power switching technology and the transformer operates in the continuous current mode to convert a continuous dc power of 10–33 W to generate a 1.2–1.6 kV 3.5 μs pulse. An argon discharge breakdown voltage of ∼768 V is measured. With a 50 kHz, pulse repetition rate and an argon flow rate of 0.5–10 argon slm (slm denotes standard liters per minute), the electrical power density deposited in …

Link Foundation Fellowship Report, Elisabeth A. Gilmore

Link Foundation Energy Fellowship Reports

Peak hour electricity demand is associated with wholesale electricity prices that are sometimes more than 10 times higher than in off-peak periods. During these high-demand periods congested transmission lines and insufficient generation capacity can lead to brownouts and blackouts. This problem can be especially acute in urban centers. One way to alleviate this problem is to build new peaking plants. We investigated the costs and benefits, including expenditures and adverse health effects, of using existing backup generators and battery based electrical storage facilities to meet peak load demands rather than investing in a new power plant. Using small-scale generation located …

Effect Of Nitrification On Lead Corrosion In Chloraminated Distribution Systems, Michael Shade

All Theses

Water treatment facilities have been shifting from using chlorination to chloramination as a primary disinfectant since 2004, when the EPA enacted the Disinfectants/Disinfection By-Products (D/DBP) Rule mandating the decrease of DBPs. After the switch to chloramination, an unexpected lead concentration increase was detected in the Washington, D. C., and Greenville, NC water systems. These increases may be associated with the switch from chlorination to chloramination. Decomposition of chloramines results in higher ammonia loading to drinking water distribution systems, which may increase nitrification. Nitrifying bacteria may facilitate lead corrosion via two mechanisms: use of nitrite or nitrate as an alternative electron …

Ceas E-News 09.16.2008, College Of Engineering And Applied Sciences

College of Engineering and Applied Sciences News

"Aspire to a Career" connects job-seekers to more than 80 employeers

Determining The Repair Ranking Of Existing Rc Bridges Using Multi-Pole Fuzzy Pattern Recognition Evaluation Method, Ming-Te Liang, Ting- Bang Chu, Wen-Hu Tsao, Chi-Jang Yeh

Journal of Marine Science and Technology–Taiwan

This paper proposes a technique for determining the repair ranking of existing reinforced concrete (RC) bridges using the multi-pole fuzzy pattern recognition evaluation method. The differences between bridges and grades are expressed by weighted generalized weight distance. To find the optimal relative membership degree of an evaluated bridge attributed to any grade, the operative principle is that the sum of the square of weighted generalized weight distance is minimum. Based on this principle, the problem of extreme value is established by the objective function in connection with constraint condition. Using the Lagrangean method, the multi-pole fuzzy pattern recognition evaluation method …

Treatability Of U.S. Environmental Protection Agency Contaminant Candidate List Viruses: Removal Of Coxsackievirus And Echovirus Using Enhanced Coagulation, Brooke K. Mayer, Hodon Ryu, Morteza Abbaszadegan

Civil and Environmental Engineering Faculty Research and Publications

Enhanced coagulation was evaluated for removal efficacy of coxsackievirus and echovirus (Contaminant Candidate List [CCL] enteroviruses), poliovirus, four potential surrogate bacteriophages, and dissolved organic carbon (DOC). Viruses and DOC were effectively removed using enhanced coagulation, with removals generally improving as dose increased and pH decreased. Optimal enhanced coagulation conditions of 40 mg/L FeCl₃ and pH between 5 and 6.5 resulted in a maximum removal of 3.0 logs of coxsackievirus B6, 1.75 logs of echovirus 12, 2.5 logs of poliovirus 1, 1.8 logs of fr, 1.3 logs of phi-X174, 0.36 logs of MS2, 0.29 logs of PRD1, and 41% DOC. …

Strain Sensitive Coax Cable Sensors For Monitoring Structures, Genda Chen, James L. Drewniak, Huimin Mu, David Pommerenke

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The invention provides increased structural monitoring systems that have sensitive continuous coaxial cable sensors. A preferred embodiment sensor cable of the invention includes an inner conductor, a dielectric jacket, and an outer conductor that is configured to passively deform responsively to strain in an associated structure. The deformation can be aided by the physical structure of the dielectric jacket, the outer conductor, or a combination of both. The deformation translates strain into a measurable change in a reflection coefficient associated with the outer conductor.

Acuta Enews September 2008, Vol. 37, No. 9

ACUTA Newsletters

In This lssue

From ACUTA Headquarters: Ramped-up Schedule................Jeri A. Semer, CAE, Executive Director

New Section on ACUTA Website

Audio Seminar: Technology-Related lmptications of the 2008 Higher Ed Opportunities Act

Tech Talk: ACUTA Member Schools Are Mostly in the Green ........ Kevin Tanzillo, Dux PR

DC Update ......... Dave Ostrom, Washington State University

lP PBX Witt Reign: Converged PBX Will Slowly Fade Away........................Gary Audin, Delphi, lnc.

Get Your ACUTA Logo here

Look on the Light Side

lnfo Links ............. Randy Hayes, Univ. of Northern lowa

Welcome New Members

Check lt Out: RFls/RFPs, Job Postings, Press Releases

Verified Methods For Computing Pareto Sets: General Algorithmic Analysis, Boglarka G.-Toth, Vladik Kreinovich

Departmental Technical Reports (CS)

In many engineering problems, we face multi-objective optimization, with several objective functions f1,...,fn. We want to provide the user with the Pareto set -- set of all possible solutions x which cannot be improved in all categories (i.e., for which fj(x')>=f_j(x) for all j and fj(x')>fj(x) for some j is impossible). The user should be able to select an appropriate trade-off between, say, cost and durability. We extend the general results about the (verified) algorithmic computability of maxima locations to show that Pareto sets can also computed.

Mining Mining Data: Bringing Empirical Analysis To Bear On The Regulation Of Safety And Health In U.S. Mining, Alison D. Morantz

West Virginia Law Review

No abstract provided.

Workers At Risk: The Unfulfilled Promise Of The Occupational Safety And Health Act, Lynn Rhinehart

West Virginia Law Review

No abstract provided.

Integrating Technology To Improve Mine Safety In The Wake Of Recent Mine Disasters, Jeffery L. Kohler

West Virginia Law Review

No abstract provided.

Free Markets, Individual Liberties And Safe Coal Mines: A Post-Sago Perspective, C. Gregory Ruffennach

West Virginia Law Review

No abstract provided.

The Failed Promise Of Workplace Health Regulation, David C. Vladeck

West Virginia Law Review

No abstract provided.

A Comparative Analysis Of Greenroof Designs Including Depth Of Media, Drainage Layer Materials, And Pollution Control Mediaa, Martin Wanielista, Michael Hardin

BMP Trains Research and Publications

No abstract provided.

Approaching Coal Mine Safety From A Comparative Law And Interdisciplinary Perspective, Anne Marie Lofaso

West Virginia Law Review

No abstract provided.

Network-Centric Localization In Manets Based On Particle Swarm Optimization, Raghavendra V. Kulkarni, Ganesh K. Venayagamoorthy, Ann K. Miller, Cihan H. Dagli

Engineering Management and Systems Engineering Faculty Research & Creative Works

There exist several application scenarios of mobile ad hoc networks (MANET) in which the nodes need to locate a target or surround it. Severe resource constraints in MANETs call for energy efficient target localization and collaborative navigation. Centralized control of MANET nodes is not an attractive solution due to its high network utilization that can result in congestions and delays. In nature, many colonies of biological species (such as a flock of birds) can achieve effective collaborative navigation without any centralized control. Particle swarm optimization (PSO), a popular swarm intelligence approach that models social dynamics of a biological swarm is …

Let's Not Abandon What Works, Edward Chair

West Virginia Law Review

No abstract provided.

Cephalometric Analysis Using Magnetic Resonance Imaging, Wade A. Williams

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose: The purpose of this study was to determine if T1-weighted 3D magnetic resonance images performed at 3.0 Tesla could be used to conduct routine orthodontic cephalometric analysis.

Methods: Three cranial imaging methods were compared using sixteen non-growing subjects (10 male and 6 female) who were not claustrophobic, did not have any metallic restorations on the distal of first molars, had no medical implants and the female subjects were not pregnant. Sagittal cranial images were produced by three methods: (1) a digital lateral cephalometric (LC) radiograph (Orthophos XG Plus, Sirona^TM, Bensheim, Germany), (2) a 12-inch FOV cone beam …

Enhanced Na+/H+ Exchange During Ischemia And Reperfusion Impairs Mitochondrial Bioenergetics And Myocardial Function, Mohammed Aldakkak, David F. Stowe, James S. Heisner, Marisha Spence, Amadou K.S. Camara

Biomedical Engineering Faculty Research and Publications

Inhibition of Na+/H+ exchange (NHE) during ischemia reduces cardiac injury due to reduced reverse mode Na+/Ca2+ exchange. We hypothesized that activating NHE-1 at buffer pH 8 during ischemia increases mitochondrial oxidation, Ca2+ overload, and reactive O2 species (ROS) levels and worsens functional recovery in isolated hearts and that NHE inhibition reverses these effects. Guinea pig hearts were perfused with buffer at pH 7.4 (control) or pH 8 +/- NHE inhibitor eniporide for 10 minutes before and for 10 minutes after 35- minute ischemia and then for 110 minutes with pH 7.4 buffer alone. Mitochondrial NADH and FAD, [Ca2+], and superoxide …

Bs News

Building Services Engineering

No abstract provided.

A Constraint Based Approach For Building Operationally Responsive Satellites, Mesut O. Kahraman

Theses and Dissertations

The Operational Responsive Space (ORS) program requires flexible and responsive satellites to meet user’s needs. Traditional satellite design methods are typically iterative processes that optimize individual components, subsystems, and ultimately the entire satellite. This study focuses on developing a new approach for creating Responsive Satellites (RS) from Plug-and-Play (PnP) components. The aim is to create an approach that quickly evaluates a wide variety of possible satellite configurations and identify the best configurations that meet the user’s needs and constraints. Satellite configurations are created by matching locations on the satellite structure with PnP components. Various constraints are derived from the user’s …

An Engineering Evaluation Of Ankle Prosthetics, Christopher Thian, Stephen Tiernan, Fiona Mcevoy, Robert Flavin

Conference Papers

There are a wide range of different types of ankle replacements on the market today each with a
different mechanical design. Unfortunately the results of ankle replacements are not as good as hip
and knee replacements; this is due to the complexity of the ankle joint. In the early days of ankle
replacements some of the prosthetics only lasted 4 months. Recent developments have improved the
longevity of the replacements although, there are still many complications and failures of the
replacements, these include; the prosthetic components migrating into the bone, the components
failing due to stresses induced by the forces …

Cryptosporidium Outbreak (Water Treatment Failure): North Battleford, Saskatchewan, Spring 2001, Patrick B. Jameson, Yung-Tse Hung, Chin Y. Kuo, Paul A. Bosela

Civil and Environmental Engineering Faculty Publications

An outbreak of cryptosporidiosis occurred in the town of North Battleford, Saskatchewan, Canada in the spring of 2001. The outbreak left thousands of people sick including about 50 people hospitalized. The source of the outbreak was from the city's surface water treatment plant. The Sedimentation Contact Unit did not satisfactorily remove suspended solids from the source water, resulting in filter breakthrough. Contaminated water was released into the distribution system causing the outbreak. Communication breakdown and confusion exacerbated the situation, extending the duration of the outbreak. The outbreak prompted the province to change the way it regulated municipal utilities of water …

Phylogenetic Reconstruction From Transpositions, Feng Yue, Meng Zhang, Jijun Tang

Faculty Publications

Background
Because of the advent of high-throughput sequencing and the consequent reduction in the cost of sequencing, many organisms have been completely sequenced and most of their genes identified. It thus has become possible to represent whole genomes as ordered lists of gene identifiers and to study the rearrangement of these entities through computational means. As a result, genome rearrangement data has attracted increasing attentions from both biologists and computer scientists as a new type of data for phylogenetic analysis. The main events of genome rearrangements include inversions, transpositions and transversions. To date, GRAPPA and MGR are the most accurate …

Pervasive Open Spaces: An Intelligent And Scalable Pervasive Environment For Providing Contextual Resource Sharing, Amgad Magdy Madkour

Archived Theses and Dissertations

No abstract provided.

Service Supply Chain Management : A Hierarchical Decision Modeling Approach, Roger Angel Solano-Cayama

Dissertations

A Service Supply Chain (SSC) may be described as a network of service provider facilities (in-house or outsourced), each of which is able to process one or more service tasks on an as needed basis. Two key characteristics of a SSC are (i) the business service is decomposable into several sequential tasks that can be processed by different service providers, and (ii) the primary capacity resource is skilled labor. SSCs are increasingly being developed by companies that experience a high variability of demand for their services (e.g., loan processing, analytical consulting services, emergency repair crews, claims processing, etc.). Typically, the …