Digital Commons Network^™

A New Pulsed Electric Field Therapy For Melanoma Disrupts The Tumor's Blood Supply And Causes Complete Remission Without Recurrence, Richard Nuccitelli, Xinhua Chen, Andrei G. Pakhomov, Wallace H. Baldwin, Saleh Sheikh, Jennifer L. Pomicter, Wei Ren, Chris Osgood, R. James Swanson, Juergen F. Kolb, Stephen J. Beebe, Karl H. Schoenbach

Bioelectrics Publications

We have discovered a new, ultrafast therapy for treating skin cancer that is extremely effective with a total electric field exposure time of only 180 mu sec. The application of 300 high-voltage (40 kV/cm), ultrashort (300 nsec) electrical pulses to murine melanomas in vivo triggers both necrosis and apoptosis, resulting in complete tumor remission within an average of 47 days in the 17 animals treated. None of these melanomas recurred during a 4-month period after the initial melanoma had disappeared. These pulses generate small, long-lasting, rectifying nanopores in the plasma membrane of exposed cells, resulting in increased membrane permeability to …

Lectures In Elementary Fluid Dynamics: Physics, Mathematics And Applications, James M. Mcdonough

Mechanical Engineering Textbook Gallery

From Chapter 1:

It takes little more than a brief look around for us to recognize that fluid dynamics is one of the most important of all areas of physics—life as we know it would not exist without fluids, and without the behavior that fluids exhibit.

It is the goal of these lecture notes to help students in this process of gaining an understanding of, and an appreciation for, fluid motion—what can be done with it, what it might do to you, how to analyze and predict it.

Kentucky Water Resources Research Institute Annual Technical Report Fy 2008, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The 2008 Annual Technical Report for Kentucky consolidates reporting requirements of the Section 104(b) base grant award into a single document that includes: 1) a synopsis of each research project conducted with grant funds during the period, 2) citations for related publications, reports, and presentations, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable awards and achievements during the year.

Abatteuses Forestières : Dispositif Et Circuits De Commande Relatifs À La Sécurité, Laurent Giraud, Yuvin Chinniah, Damien Burlet-Vienney, Joseph-Jean Paques, Marina Koutchouk, Renaud Daigle

Rapports de recherche scientifique

Les abatteuses forestières sont des engins tout-terrains conçus pour évoluer en forêt, qui servent de véhicule moteur pour déplacer une tête d’abattage.

L’utilisation d’abatteuses avec une tête d’abattage multifonctionnelle s’est largement répandue au Québec ces dernières années pour deux raisons :

• Cette méthode d’abattage réduit la machinerie car une seule machine tronçonne et façonne les arbres en billots, là où il en fallait plusieurs avec les anciennes méthodes;
• La méthode d’abattage abîme moins le sol de la forêt car le façonnage des arbres se fait sur place et crée ainsi un tapis végétal.

L’IRSST a lancé une série d’études sur …

The Journal Of Undergraduate Research: Volume 07

The Journal of Undergraduate Research

This is the complete issue of the South Dakota State University Journal of Undergraduate Research, Volume 7.

Damage Characterization Of Beam-Column Joints Reinforced With Gfrp Under Reversed Cyclic Loading, Aly M. Said

Civil and Environmental Engineering and Construction Faculty Research

The use of fiber reinforced polymer (FRP) reinforcement in concrete structures has been on the rise due to its advantages over conventional steel reinforcement such as corrosion. Reinforcing steel corrosion has been the primary cause of deterioration of reinforced concrete (RC) structures, resulting in tremendous annual repair costs. One application of FRP reinforcement to be further explored is its use in RC frames. Nonetheless, due to FRP's inherently elastic behavior, FRP-reinforced (FRP-RC) members exhibit low ductility and energy dissipation as well as different damage mechanisms. Furthermore, current design standards for FRP-RC structures do not address seismic design in which the …

Nanofiltration Membrane Pilot Studies For Disinfection By-Product Control, Eric J. Lynne

Electronic Theses and Dissertations

Watertown, South Dakota currently uses conventional softening to treat ground water to remove hardness, iron and manganese, and natural organic matter. The distribution system has experienced elevated concentrations of disinfection by-products, which will require additional treatment to comply with future limits set by the Stage 2 Disinfectant/Disinfection By-Products Rule. A nanofiltration membrane system has been proposed to remove additional natural organic matter from the softened water. Removing the natural organic material disinfection by-product precursors should reduce the concentration of disinfection by-products. The use of nanofiltration membranes has been previously documented to reject total organic carbon, while allowing desirable levels of …

Auto Racing, John Alfred Heitmann

History Faculty Publications

As a consequence of new sponsors, personalities, race tracks, and television exposure, automobile racing — and in particular NASCAR — reached unprecedented popularity during the 1990s. Indeed, NASCAR became a "way of life" for many Americans.

Proceedings Of The Iccbr 2009 Workshops, Sarah Jane Delany

Books/Book chapters

In 2009 the workshop programme includes four workshops, two of which are workshops in well recognised CBR research areas continuing the well established,successful workshops on Case-Based Reasoning in the Health Sciences and on Uncertainty, Knowledge Discovery and Similarity. There are also two new workshops which explore developing areas of CBR research, namely Reasoning from Experiences on the Web (WebCBR) and Case-Based Reasoning for Computer Games.

A Mobile Ecg Monitoring System With Context Collection, Jin Peng Li, Damon Berry, Richard Hayes

Conference Papers

Preventative health management represents a shift from the traditional approach of reactive treatment-based healthcare towards a proactive wellness-management approach where patients are encouraged to stay healthy with expert support when they need it, at any location and any time. This work represents a step along the road towards proactive, preventative healthcare for cardiac patients. It seeks to develop a smart mobile ECG monitoring system that requests and records context information about what is happening around the subject when an arrhythmia event occurs. Context information about the subject’s activities of daily living will, it is hoped, provide an enriched data set …

Modeling And Calculation Of Electromagnetic Field In The Surroundings Of A Large Power Transformer, Leonardo Strac, Franjo Kelemen, Damir Zarko

Turkish Journal of Electrical Engineering and Computer Sciences

The presented study compares measured and calculated electromagnetic field quantities in the surroundings of a large power transformer with the aim to avoid the necessity of measuring the field on subsequent units and use a computer model instead. The influences of various objects located in the vicinity of the transformer during measurement are also analyzed and are taken into account in a computer model.

Highway Bridge Assessment For Dynamic Interaction With Critical Vehicles, Daniel Cantero, Eugene J. Obrien, Arturo González, Bernard Enright, Cillian Rowley

Conference papers

Dynamic vehicle-bridge interaction is often considered for the most common classes of vehicle such as the 5-axle articulated truck. However, the dynamic response of bridges to this type of trucks is quite different to the response to the vehicles more likely to feature in maximum-in-lifetime traffic loading events. This paper focuses on large (>100 tonne) cranes and crane-type vehicles that have been recorded at Weigh-in-Motion sites in Europe. This paper analyses the total bending moment due to these vehicles on short to medium span bridges and compare them to 5- axle articulated trucks. To account for the variability in …

Program And Proceedings: Nebraska Academy Of Sciences 1880–2009, 129th Anniversary Year, One Hundred-Nineteenth Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

Program

Aeronautics and Space Science

Collegiate Academy: Biology

Earth Science

Collegiate Academy: Chemistry and Physics

Biological and Medical Sciences

Nebraska Wesleyan University Health and Sciences Graduate School Fair

Junior Academy: Senior High Competition

Aeronautics and Space Science, Poster Session

History and Philosophy of Science

Teaching of Science and Math

Maiben Memorial Lecture: Donald Frey, Department of Family Practice, Creighton University Medical Center

Anthropology

Chemistry and Physics

Junior Academy, Junior High Competition

Nanocomposite Thin Films Of Au Nanoparticles Embedded In Yttria-Stabilized Zirconia For Plasmonic-Based Harsh Environment Gas Detection, Phillip Henry Rogers

Legacy Theses & Dissertations (2009 - 2024)

Increased health concerns due to the emission of gases linked to the production of tropospheric ozone by petroleum based fuel burning engines has resulted in the codification of more stringent emissions regulations domestically. Emissions regulations on commercial jetliners are one of the areas to be met with stricter standards. Currently there is not a sensing technology that can detect the emissions gases in the exhaust stream of a jet turbine engine with lower detection limits that meet these standards.

Three-Dimensional Hydrogel Cell Culture Systems For Modeling Neural Tissue, John P. Frampton

Legacy Theses & Dissertations (2009 - 2024)

Two-dimensional (2-D) neural cell culture systems have served as physiological models for understanding the cellular and molecular events that underlie responses to physical and chemical stimuli, control sensory and motor function, and lead to the development of neurological diseases. However, the development of three-dimensional (3-D) cell culture systems will be essential for the advancement of experimental research in a variety of fields including tissue engineering, chemical transport and delivery, cell growth, and cell-cell communication. In 3-D cell culture, cells are provided with an environment similar to tissue, in which they are surrounded on all sides by other cells, structural molecules …

Biotechnology For Immune Cell Detection And Evaluation : Devices Specifically Designed To Capture, Detect Or To Evaluate Alterations In Leukocyte Structure And Function, Thomas Joseph Zieziulewicz

Legacy Theses & Dissertations (2009 - 2024)

The advent of Nano-biotechnology has opened a whole new area of biological study that has allowed us to pattern, manipulate, separate, evaluate and detect biological structures and functions that were previously not possible. This dissertation will describe different types of micro-fabricated devices that were designed to quantify and/or evaluate the functional activities of cells of the immune system. The micro-fabricated devices were developed in collaboration with our colleagues at Princeton University as part of our Cellular Micro-dynamics Program of the Nanobiotechnology Center (NBTC) at Cornell University.

Perchlorate In Wet Deposition Across North America, Srinath Rajagopalan, Todd A. Anderson, Stephen Cox, Greg Harvey, Qiuqiong Cheng, W. Andrew Jackson

United States Air Force: Publications

Natural perchlorate is believed to be of atmospheric origin, yet no systematic study has been conducted to evaluate perchlorate deposition rate and possible seasonal or spatial variations. This study evaluated perchlorate concentrations in weekly composite wet deposition samples acquired through the National Atmospheric DepositionProgramfrom 26 sites across the continental United States, Alaska, and Puerto Rico for a 1-3 year period. Perchlorate concentrations varied from /L to a high of 102 ng/L with a mean of 14.1±13.5 ng/L for the 1578 total samples. The annual perchlorate flux by site ranged from a low of 12.5 (TX) to 157 mg/ha-year (NE) and …

A Location Analysis Approach For Military Maintenance Scheduling With Geographically Dispersed Service Areas, Dale L. Overholts Ii, John E. Bell, Marvin A. Arostegui

United States Air Force: Publications

This research uses a two-stage maximal covering location problem (MCLP) model to develop Intercontinental ballistic missile (ICBM) maintenance schedules for the US Air Force. Solutions are compared to actual missile maintenance activities accomplished at F. E. Warren Air Force Base (AFB), Wyoming in May 2005. Sensitivity analysis is performed to determine the impact of altering security response times and the number of security patrol are as on the quality of daily maintenance schedules and personnel usage. Results indicate marked improvement over traditional Air Force scheduling methods. In addition, sensitivity analysis identifies the levels at which the quality and quantity of …

Performance-Engineered Network Overlays For High Quality Interaction In Virtual Worlds, Mart Haitjema, Ritun Patney, Jon Turner, Charlie Wiseman, John Dehart

All Computer Science and Engineering Research

Overlay hosting systems such as PlanetLab, and cloud computing environments such as Amazon’s EC2, provide shared infrastructures within which new applications can be developed and deployed on a global scale. This paper ex-plores how systems of this sort can be used to enable ad-vanced network services and sophisticated applications that use those services to enhance performance and provide a high quality user experience. Specifically, we investigate how advanced overlay hosting environments can be used to provide network services that enable scalable virtual world applications and other large-scale distributed applications requiring consistent, real-time performance. We propose a novel network architecture called …

Enhanced Coordination In Sensor Networks Through Flexible Service Provisioning, Chien-Liang Fok, Gruia-Catalin Roman, Chenyang Lu

All Computer Science and Engineering Research

Heterogeneous wireless sensor networks represent a challenging programming environment. Servilla addresses this by offering a new middleware framework that provides service provisioning. Using Servilla, developers can construct platform-independent applications over a dynamic set of devices with diverse computational resources and sensors. A salient feature of Servilla is its support for dynamic discovery and binding to local and remote services, which enables flexible and energy-efficient in-network collaboration among heterogeneous devices. Furthermore, Servilla provides a modular middleware architecture that can be easily tailored for devices with a wide range of resources, allowing resource-constrained devices to provide services while leveraging the capabilities of …

Adaptive Service Provisioning For Wireless Sensor Networks, Chien-Liang Fok, Gruia-Catalin Roman, Chenyang Lu

All Computer Science and Engineering Research

Service provisioning has gained significant attention as a promising programming model for heterogeneous wireless sensor networks. Its key idea is to exploit the decoupling of service providers and consumers to enable platform-independent applications that are dynamically bound to platform-specific services. We explore novel adaptive service binding strategies that are able to cope with network dynamics and to promote energy conservation. To achieve this goal, we developed policies and algorithms that automatically switch providers in response to network topology changes and adapt application behavior when opportunities for energy savings surface. The latter is accomplished by providing limited information about the energy …

University Place, Sarah Digiulio, David Marc, Krista Flynt, Timeka Williams, Christine Yackel, Jay Cox

Syracuse University Magazine

No abstract provided.

Retrofitting Tractors With Rollover Protective Structures: Perspective Of Equipment Dealers, Shalome M. Tonelli, Kelley J. Donham, Kerry Leedom-Larson, Wayne Sanderson, Mark A. Purschwitz

Biosystems and Agricultural Engineering Faculty Publications

This study was one of a cluster of studies that originated via requests for proposals from the NIOSH National Agricultural Tractor Safety Initiative. The present study design consisted of several steps: (1) formation of an advisory group, (2) development and testing of a standard paper self-responding survey instrument, (3) sample selection of farm equipment dealers, (4) administration of the survey, (5) assessment and analysis of the survey, and (6) in-person response panel of dealers (n = 80) to review results of the questionnaire for further definition and sharpening of the recommendations from the survey. A key finding is that most …

An Introduction To Dezert-Smarandache Theory (Dsmt), Jean Dezert, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The management and combination of uncertain, imprecise, fuzzy and even paradoxical or highly conflicting sources of information has always been, and still remains today, of primal importance for the development of reliable modern information systems involving artificial reasoning. In this introduction, we present a survey of our recent theory of plausible and paradoxical reasoning, known as Dezert-Smarandache Theory (DSmT), developed for dealing with imprecise, uncertain and conflicting sources of information. We focus our presentation on the foundations of DSmT and on its most important rules of combination, rather than on browsing specific applications of DSmT available in literature. Several simple …

Rapid Sensor Technology: A Risk And System Complexity Analyses Of Early Detection Of Influenza-Like-Illnesses, Cesar Ariel Pinto, Ipek Bozkurt

Engineering Management & Systems Engineering Faculty Publications

The development of effective and reliable methods to defend the nation against biological terrorism remains an urgent challenge to researchers in the areas of risk, bio-defense, public health, and emergency medicine. The emerging threat of the avian flu pandemic also highlights the unpreparedness of our nation's health care system to meet a highly contagious and infectious disease outbreak. The implementation of a rapid sensor technology for early detection of influenza-like-illness provides possible opportunities, as well as problems. Bounding and defining such a complex problem is one of the first challenges this research addresses. Approaching this problem from various perspectives such …

A Systematic Analysis To Identify, Mitigate, Quantify, And Measure Risk Factors Contributing To Falls In Nasa Ground Support Ope, Joylene Ware

Electronic Theses and Dissertations

The objective of the research was to develop and validate a multifaceted model such as a fuzzy Analytical Hierarchy Process (AHP) model that considers both qualitative and quantitative elements with relative significance in assessing the likelihood of falls and aid in the design of NASA Ground Support Operations in aerospace environments. The model represented linguistic variables that quantified significant risk factor levels. Multiple risk factors that contribute to falls in NASA Ground Support Operations are task related, human/personal, environmental, and organizational. Six subject matter experts were asked to participate in a voting system involving a survey where they judge risk …

Analysis Of The Physical Forcing Mechanisms Influencing Salinity Transport For The Lower St. Johns River, Derek Giardino

Electronic Theses and Dissertations

The focus of this thesis is the forcing mechanisms incorporated with salinity transport for the Lower St. Johns River. There are two primary analyses performed: a historical data analysis of primary forcing mechanisms to determine the importance of each individual influence, and a tidal hydrodynamics analysis for the Lower St. Johns River to determine the required tidal constituents for an accurate resynthesis. This thesis is a preliminary effort in understanding salinity transport for the Lower St. Johns River for engineering projects such as the dredging of navigation canals and freshwater withdrawal from the river. The analysis of the physical forcing …

Nutrient And Pathogen Removal In A Subsurface Upflow Wetland System Using Green Sorption Media, Zhemin Xuan

Electronic Theses and Dissertations

Due to environmental health and nutrient impact concerns, the conventional on-site sewage collection, treatment, and disposal systems are no longer able to meet the nutrient reduction requirements for wastewater effluent and may represent a large fraction of pollutant loads. The loads include not only nitrogen (N) and phosphorus (P), but also pathogens such as fecal coliform and E. coli which indicate the presence of other disease-causing bacteria flowing into aquatic system that adversely affect public health. A subsurface upflow wetland, which is an effective small-scale wastewater treatment system with low energy and maintenance requirements and operational costs, fits the current …

Concurrent Simulation Of Neuromuscular Control And Tissue Deformation Is Possible By Adaptive Surrogate Modeling, Jason P. Halloran, Ahmet Erdemir, Antonie J. Van Den Bogert

Mechanical Engineering Faculty Publications

No abstract provided.

Adaptive Surrogate Modeling For Efficient Coupling Of Musculoskeletal Control And Tissue Deformation Models, Jason P. Halloran, Ahmet Erdemir, Antonie J. Van Den Bogert

Mechanical Engineering Faculty Publications

Background

Finite element (FE) modeling and multibody dynamics have traditionally been applied separately to the domains of tissue mechanics and musculoskeletal movements, respectively. Simultaneous simulation of both domains is needed when interactions between tissue and movement are of interest, but this has remained largely impractical due to high computational cost.

Method of Approach

Here we present a method for concurrent simulation of tissue and movement, in which state of the art methods are used in each domain, and communication occurs via a surrogate modeling system based on locally weighted regression. The surrogate model only performs FE simulations when regression from …