Digital Commons Network^™

Towards Dynamical Systems Approach To Fuzzy Clustering, Vladik Kreinovich, Olga Kosheleva

Departmental Technical Reports (CS)

In many application areas, there is a need for clustering, and there is a need to take fuzzy uncertainty into account when clustering. Most existing fuzzy clustering techniques are based on the idea that an object belongs to a certain cluster if this object is close to a typical object from this cluster. In some application areas, however, this idea does not work well. One example of such application is clustering in education that is used to convert a detailed number grade into a letter grade.

In such application, it is more appropriate to use clustering techniques which are based …

Free Fridays: An Alternative Way To Conserve Energy, Lauren Kuenzel

Mechanical Engineering Undergraduate Honors Theses

In February 2007, the University of Arkansas at Fayetteville (UAF) signed the President's Climate Commitment to set a goal of becoming climate neutral. A large part of any strategy to become climate neutral includes energy conservation. In light of that, a four-day school week is proposed for UAF as an alternative energy savings possibility. This reduced schedule has been applied to K-12 schools and state government institutions, but not yet to universities. Along with numerous benefits such as energy conservation of buildings on the free day, a more effective use of time and building space and the positive emotional repercussions …

Testing And Monitoring Concrete Using Novel Methods For Predicting Their Long Term Behaviour, Sreejith Nanukuttan, Lulu Basheer, Muhammed Basheer, Niall Holmes, John Mccarter, Malcolm Chrisp, Gerry Starrs

Conference papers

It is widely recognised that durability of concrete depends on its transport properties, viz. absorption, diffusion and permeability. As concrete cover provides the first line of defence against the ingress of many deleterious substances into the concrete, a measure of its transport properties is vital in assessing its long term performance in the given exposure condition. In new structures the rate of ingress of the deleterious substances could be monitored using array of electrical sensors which are embedded in the cover concrete. For structures which are currently in service, two in situ permeability apparatuses, viz. Autoclam Permeability System (for measuring …

Adhesion Of Jurkat Cells In Defined Media And Substrates, Sarah De Leo

Honors Capstones

No abstract provided.

Effect Of Molecular Weight Reduction By Gamma Irradiation On The Antimicrobial Activity Of Chitosan, Ebuel Sirmats

All Theses

The antimicrobial effectiveness of lower molecular weight (LMW) chitosan solutions was tested against Listeria innocua inoculated on TSA and MOX agar plates by the direct droplet method. The chitosan solutions were prepared by dissolving chitosan in 1% (v/v) acetic acid at concentrations ranging from 0.5 to 2.0% and irradiating with Co60 gamma rays ranging from 1 to 20 kGy. MW measurements of chitosan were determined by using HPSEC-MALLS-RI. The MW of chitosan varied from 114.8 kDa to 17.4 kDa and decreased with increasing irradiation dosages. Plate counts on TSA agar from shaker flask assays showed no significant differences among chitosan …

An Investigation Of Human Induced Vibrations On Clemson Memorial Stadium, Benjamin Morris

All Theses

Human induced stadium vibrations have become of increasing concern to design engineers and facility managers as more energetic crowds and increasingly efficient structures have increased the likelihood of serviceability issues. The 'in-time' bouncing of spectators due to music has caused one such issue in the south upper deck of Clemson University's Memorial Stadium. To gain an understanding of the severity of vibrations in Memorial Stadium, a combination of experimental and analytical modeling is utilized. Data collected by an array of accelerometers installed on a main post tensioned precast cantilever girder provides a season and a half of response histories in …

Theoretical Analysis Of Alendronate And Risedronate Effects On Canine Vertebral Remodeling And Microdamage, Xiang Wang, Antonia M. Erickson, Matthew R. Allen, David B. Burr, R. Bruce Martin, Scott J. Hazelwood

Biomedical Engineering

Bisphosphonates suppress bone remodeling activity, increase bone volume, and significantly reduce fracture risk in individuals with osteoporosis and other metabolic bone diseases. The objectives of the current study were to develop a mathematical model that simulates control and 1 year experimental results following bisphosphonate treatment (alendronate or risedronate) in the canine fourth lumbar vertebral body, validate the model by comparing simulation predictions to 3 year experimental results, and then use the model to predict potential long term effects of bisphosphonates on remodeling and microdamage accumulation. To investigate the effects of bisphosphonates on bone volume and microdamage, a mechanistic biological model …

Detection Of Escherichia Coli Using The Bacteriophage-Based Fluorescent Technique, Aung Khaing

Biological and Agricultural Engineering Undergraduate Honors Theses

The detection of viable Escherichia coli (E. coli) by the bacteriophage-based fluorescent technique using the enhanced green fluorescent protein (EGFP) was tested in this project. EGFP, a mutant of green fluorescent protein (GFP), was used due to its high fluorescent efficiency compared to wild-type GFP. First, E. coli bacteria were cultured to the mid-exponential phase in the 2× YT medium and then they were infected with the M13 bacteriophages containing the EGFP gene. Infected bacteria were incubated for different time intervals, and the expression of EGFP on the E. coli membrane was tested by the PerkinElmer LS 55 Luminescence Spectrometer, …

Magnetic Sensors For Biodetection, Pranjali Vineet Sneha Deshpande

UNLV Theses, Dissertations, Professional Papers, and Capstones

The objective of thesis is to design magnetic sensor for detection of nanoparticles. Recently integrating the standard laboratory techniques into integrated system on chip is growing attention. Recent development is to combine magnetic markers and magnetoresistive sensors together in magnetic chip. In this thesis two magnetoresistive sensors were studied and designed.

By applying magnetic fields, magnetic nanoparticles can be manipulated on-chip, which can be utilized to pull the molecules to specific binding sites or to test the binding strength and distinguish between specifically and non-specifically bound molecules

Magnetoresistive sensors are compatible with the semiconductor industry which provides electronic signal directly …

Investigation Of Magnetic Resonance Imaging And Spectroscopy For The Detection Of Breast Cancer, Robert Thomas Etnire

UNLV Theses, Dissertations, Professional Papers, and Capstones

Magnetic resonance imaging (MRI) of the breast offers an alternative to screening mammography which may benefit those women at high risk for breast cancer, women under the age of 40, and those with dense breast tissue. One concern with MRI is the number of high false positives. Coupling MRI with magnetic resonance spectroscopy(MRS) may lower the number of false positives, and thus improve the diagnostic capabilities of MRI for the clinician. MRS for breast imaging focuses on the total choline containing compounds in the spectra in the suspected breast lesion to analyze areas of concern. The results of the study …

The Influence Of Carbon Source Types And Nitrate On The Performance Of The Enhanced Biological Phosphorus Removal Systems, Shamim Ara Begum

UNLV Theses, Dissertations, Professional Papers, and Capstones

This research focuses on two issues in enhanced biological phosphorus removal (EBPR). The first issue encompasses the effect of the type of carbon sources (i.e. volatile fatty acids and non volatile fatty acids) on the microbiology of EBPR. The second issue deals with the influence of denitrification on EBPR. Few studies have been performed to investigate these two issues. The recent findings on these areas are summarized below to establish the knowledge gaps this dissertation attempted to address. Details on the specific findings can be found in the literature review portion of this proposal.

Investigation Of Feasibility And Potential Mechanisms For The Bioregeneration Of Perchlorate Laden Gel-Type Anion Exchange Resin, Arjun Krishna Venkatesan

UNLV Theses, Dissertations, Professional Papers, and Capstones

The feasibility and potential mechanisms for the bioregeneration of perchlorate laden gel-type anion exchange resin were investigated in this study. Bioregeneration is a sustainable process when compared to one time use of resin and disposal by incineration. Batch and bench-scale bioregeneration experiments were performed to evaluate the feasibility of the process and to gain insight into potential mechanisms that control gel-type resin bioregeneration. The results of the bioregeneration tests suggested that the initial phase of the bioregeneration process is controlled by kinetics, while the later phase is controlled by diffusion. Higher perchlorate load in the resin had a positive effect …

Analysis Of Ecosystem Services At Mullins Creek On The University Of Arkansas Campus, Kathryn Mccoy

Biological and Agricultural Engineering Undergraduate Honors Theses

The University of Arkansas has been a site of population and urban growth since its inception in 1871. This urban development has caused extreme changes in land use, and with this has also come a change in ecosystem services provided by the area. Ecosystem services are benefits acquired by humans that are provided by functions are an ecosystem (Constanza et al., 1997). Constanza developed a method for quantifying ecosystem services. In this method, Constanza valuated ecosystem services for biomes. These service values were based on the economic value of the service provided, and were given in dollar per hectare-year. A …

Analysis Of Phase Ii Metabolites Of Methamphetamine By Solid-Phase Extraction And Liquid Chromatography With Tandem Mass Spectrometric Detection, Jordan Carbary, Howard P. Hendrickson

Biological and Agricultural Engineering Undergraduate Honors Theses

Methamphetamine (METH) abuse is one of the most serious health problems in the United States and Europe due to its addictive properties and potential neurotoxic effects [1, 2, 3]. METH abuse appears to have stabilized or decreased slightly in the general populations, however abuse in certain populations is increasing [4, 5]. Treatments for drug abuse are often tested in animal behavioral pharmacology models. One of the first in vivo tests conducted in animals is to follow the concentration of the drug and its metabolites as a function of time. In this way, one can determine how long a potential medication …

Carbon Nanotube Cluster Based Micro-Fluidic System For Bacteria Capture, Concentration, And Separation, Christopher Nelson

Biological and Agricultural Engineering Undergraduate Honors Theses

Disease-causing pathogens continue presenting enormous global health problems, especially due to their easy transmittance to people via water supply systems. The detection, filtration, and purification of bacteria contaminated water samples are complex and subject to a great amount of error. Here we present a new and highly effective micro-fluidic system with carbon nanotube clusters for effective and efficient detection, filtration, and purification of bacteria contaminated medium. The developed system is based upon two unique properties of carbon nanotubes (CNTs): high bacterial affinity and magnetic susceptibility. The CNTs' high affinity to bacteria cells makes them a key candidate for the bacteria …

A Tissue Engineering Approach To Anterior Cruciate Ligament, Kristofer Sinclair

All Dissertations

Ruptures of the anterior cruciate ligament (ACL) are the most frequent of injuries to the knee due to its role in preventing anterior translation of the tibia. It is estimated that as many as 200,000 Americans per year will suffer from a ruptured ACL, resulting in management costs on the order of 5 billion dollars. Without treatment these patients are unable to return to normal activity, as a consequence of the joint instability found within the ACL deficient knee.
Over the last thirty years, a variety of non-degradable, synthetic fibers have been evaluated for their use in ACL reconstruction; however, …

Development Of Strategies For Enhanced In Situ Bioremediation Of High Concentrations Of Halogenated Methanes, Huifeng Shan

All Dissertations

ABSTRACT
Bioremediation of high concentrations of halomethanes e.g., carbon tetrachloride (CT), trichlorofluoromethane (CFC-11) and chloroform (CF) has seldom been addressed before and remains highly challenging. A microcosm study was conducted to investigate bioremediation strategies for groundwater contaminated with CT (6 to 10 mg/L), CFC-11 (1 to 26 mg/L), CF (3-500 mg/L), and 1,1-dichloroethene (1,1-DCE; up to 9 mg/L) at a former industrial site in California. Biostimulation with corn syrup and catalytic amounts of vitamin B₁₂ was demonstrated as a feasible remedial strategy and bioaugmentation with B₁₂ represents the most promising bioremediation method of the ones studied. Halomethane transformation …

Automated Identification Of Tumor Microscopic Morphology Based On Macroscopically Measured Scatter Signatures, Pilar Beatriz Garcia-Allende, Venkataramanan Krishnaswamy, P Jack Hoopes, Kimberley S. Samkoe, Olga M. Conde, Brian W. Pogue

Dartmouth Scholarship

An automated algorithm and methodology is presented to identify tumor-tissue morphologies based on broadband scatter data measured by raster scan imaging of the samples. A quasi-confocal reflectance imaging system was used to directly measure the tissue scatter reflectance in situ, and the spectrum was used to identify the scattering power, amplitude, and total wavelength-integrated intensity. Pancreatic tumor and normal samples were characterized using the instrument, and subtle changes in the scatter signal were encountered within regions of each sample. Discrimination between normal versus tumor tissue was readily performed using a K-nearest neighbor classifier algorithm. A similar approach worked …

Box Redesign: Eliminating Waste And Improving Space Utilization By Reducing Box Pallet Footprint, Kimberly M. Harris

Masters Theses and Doctoral Dissertations

The XYZ Corporation is headquartered in Dalton, GA. It is a full service flooring company with approximately 30,000 employees. The company sells woven and tufted broadloom carpet and other flooring products in Canada, Mexico and the U.S., and exports worldwide. One of their projects is to develop an improve d packaging design, which will help in streamlining the internal packaging and distribution process. The aim of this research is to eliminate waste and improve the use of shipping pallets to reduce the amount of footprint used by applying techniques of lean manufacturing systems. To understand the existing packaging method, a …

The I-70 Greenfield Rest Area Wetland Projects, Shih-Chieh Kao, Ting Pong Chang, Rebeka Sultana, Thomas Konopka, Rao S. Govindaraju, Barry Partridge

JTRP Technical Reports

On-site treatment of wastewater at highway rest areas poses some unique and difficult challenges because of the rural locale, high variability in wastewater flow rate and strength, and lack of knowledgeable personnel on-site. As a potential alternative, a constructed subsurface wetland system was built at the I-70 rest stop nearby Greenfield, Indiana, in 2003. This wetland system, mainly composed of three wetland cells, also includes draw-and-fill and recirculation mechanisms to increase oxygen transfer to the wastewater and improve the overall treatment performance. Special considerations for highway rest areas have been emphasized. A dynamic hydraulic model was developed to help characterize …

Adsorption-Induced Changes In Enzyme Bioactivity Correlated With Adsorbed Protein Orientation And Conformation, Kenan Fears

All Dissertations

Systems using immobilized enzymes are attractive for a wide range of industrial and medical applications because they allow for fabrication of stable, reusable substrates with a highly specific functionality. The performance of these systems is greatly influenced by the orientation and conformation of the immobilized enzymes. To investigate these relationships, we have developed and applied methods to quantitatively assess the secondary structure of adsorbed enzyme layers on planar surfaces using circular dichroism (CD) spectropolarimetry and evaluate their bioactivity using colorimetric assays. When combined with knowledge of an enzyme's native structure, these methods provide a means to correlate changes in enzyme …

Proximate Characterization And Lycopene Determination In Bitter Melon Seed Aril, Luis Raul Jimenez Interiano

Chemical Engineering Undergraduate Honors Theses

Bitter melon aril is the mucilage covering the fruit's seeds which could contain beneficial dietary ingredients. The bright red color of bitter melon aril suggests that it could contain lycopene. The purpose of this study was to determine the proximate composition of bitter melon aril and to explore this material as a potential rich source of lycopene that has health benefits. Bitter melon aril from Sri Lanka, harvested in Arkansas, USA in 2005, 2006, and 2007 was analyzed. An investigation to develop an extraction method for lycopene from bitter melon was performed using liquid-liquid and a polar liquid extraction. The …

Development Of An In-Vitro Tissue Engineered Blood Vessel Mimic Using Human Large Vessel Cell Sources, Dimitri E. Delagrammaticas

Master's Theses

Tissue engineering is an emerging field that offers novel and unmatched potential medical therapies and treatments. While the vast aim of tissue engineering endeavors is to provide clinically implantable constructs, secondary applications have been developed to utilize tissue-engineered constructs for in-vitro evaluation of devices and therapies. Specifically, in-vitro blood vessel mimics (BVM) have been developed to create a bench-top blood vessel model using human cells that can be used to test and evaluate vascular disease treatments and intravascular devices. Previous BVM work has used fat derived human microvascular endothelial cells (EC) sodded on an ePTFE scaffold. To create a more …

Bioresorbable Film For The Prevention Of Adhesion To The Anterior Spine After Anterolateral Discectomy, Lisa S. Klopp, Jeffrey M. Toth, William C. Welch, Sangeeta Rao, Joseph W. Tai, Kevin A. Thomas, Simon Turner

Biomedical Engineering Faculty Research and Publications

Background context

The development of scar tissue and adhesions postoperatively is a natural consequence of healing but can be associated with medical complications and render reoperation difficult. Many biocompatible products have been evaluated as barriers or deterrents to adhesions.

Purpose

To evaluate the efficacy of a bioresorbable polylactide film as a barrier to adhesion formation after anterolateral discectomy.

Study design

Experimental study.

Methods

Seven, skeletally mature female sheep underwent a retroperitoneal approach to the anterolateral lumbar spine. A discectomy was performed at two levels with an intervening unoperated disc site. One site was treated with a polylactide film barrier (Hydrosorb …

Hydrologic Information Systems: Advancing Cyberinfrastructure For Environmental Observatories, Jeffery S. Horsburgh

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Recently, community initiatives have emerged for the establishment of large-scale environmental observatories. Cyberinfrastructure is the backbone upon which these observatories will be built, and scientists' ability to access and use the data collected within observatories to address research questions will depend on the successful implementation of cyberinfrastructure. The research described in this dissertation advances the cyberinfrastructure available for supporting environmental observatories. This has been accomplished through both development of new cyberinfrastructure components as well as through the demonstration and application of existing tools, with a specific focus on point observations data. The cyberinfrastructure that was developed and deployed to support …

Water Allocation For Agricultural Use Considering Treated Wastewater, Public Health Risk, And Economic Issues, Ahmed E. Al-Juaidi

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Increasing demand on limited water resources calls for more efficient and improved approaches to maximize the benefits of water use. Typically, agricultural water use has the largest share among all water use sectors. Therefore, finding the best agricultural water management alternatives to maximize profit and reduce financial and other related risks under limited water availability is essential. Treated wastewater is an important alternative source of agricultural water which has the potential to reduce the stress on freshwater sources from urban and industrial sectors. Thus, further research on optimal agricultural water management is needed to find the best management alternatives that …

Inducing A Normal Phenotype In Breast Epithelial Cells Using A Three-Dimensional Basement Membrane Extract Culture System: A Study On The Reversion Of Cancer, Ross H. Booth

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Experimentally, traditional developmental models and transgenic animals consistently underscore the importance of studying cell behavior in the correct tissue context. However, live animal experimentation is inherently complex, and systematic assessment of the effects of individual variables, such as cell shape and matrix compliance on cell behavior, is extremely difficult at best. Two-dimensional monolayer culture of key individual cell types has provided abundant, fundamental information on cell response, but cannot be used to show the normal phenotype of breast epithelial cells. Furthermore, their results often fail to translate into in vivo and clinical studies. It has been previously established that normal …

Measurement Of Air Pollutant Emissions From A Confined Poultry Facility, Olumuyiwa Omotola Ogunlaja

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Air emissions from animal feeding operations have become a growing concern. Much work has been done to study occupational exposures and the exhaust concentrations associated with animal facilities; however little information has been provided about air quality around the houses. Ammonia (NH₃ ), ethanol (EtOH), nitrous oxide (N₂O), carbon dioxide (CO₂), and particulate matter (PM _2.5 and PM₁₀) emissions were monitored in two different buildings for laying hens in northern Utah. Over the six-month sampling period, the observed average temperatures for the west and east fan banks of the high-rise building were 21.2±4 …

Development Of A New Lagrangian Float For Studying Coastal Marine Ecosystems, Alex Schwithal, Chris Roman

Graduate School of Oceanography Faculty Publications

This paper presents an overview and initial testing results for a shallow water Lagrangian float designed to operate in coastal settings. The presented effort addresses the two main characteristics of the shallow coastal environment that preclude the direct of use of many successfully deep water floats, namely the higher variation of water densities near the coast compared with the open ocean and the highly varied bathymetry. Our idea is to develop a high capacity dynamic auto-ballasting system that is able to compensate for the expected seawater density variation over a broad range of water temperatures and salinities while using measurements …

Vascular Injury After Whole Thoracic X-Ray Irradiation In The Rat, S. N. Ghosh, Q. Wu, M. Mäder, B. L. Fish, John E. Moulder, Elizabeth R. Jacobs, Meetha Medhora, Robert C. Molthen

Biomedical Engineering Faculty Research and Publications

Purpose

To study vascular injury after whole thoracic irradiation with single sublethal doses of X-rays in the rat and to develop markers that might predict the severity of injury.

Methods and Materials

Rats that received 5- or 10-Gy thorax-only irradiation and age-matched controls were studied at 3 days, 2 weeks, and 1, 2, 5, and 12 months. Several pulmonary vascular parameters were evaluated, including hemodynamics, vessel density, total lung angiotensin-converting enzyme activity, and right ventricular hypertrophy.

Results

By 1 month, the rats in the 10-Gy group had pulmonary vascular dropout, right ventricular hypertrophy, increased pulmonary vascular resistance, increased dry lung …