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Application Of Differential Scanning Calorimetry To Characterize Thin Film Deposition Processes, Andrew John Roger Snell

ETD Archive

With the recent increase in awareness on the environmental impact of industrial coating processes, chromate-based coating processes have been elevated to the rank of the technologies targeted by the EPA for rapid replacement by environmentally friendly processes. Therefore, there is a clear need for advances in coating technologies to identify alternative industrial practices. This thesis characterizes a process developed at Cleveland State University as an alternative deposition technique to generate uniform coatings onto solid substrates. A kinetic analysis to extract scale up parameters involved in the reaction kinetics leading to high-performance coatings is demonstrated in this research. The work consists …

Geochemical Investigations Of Metals Release From Submerged Coal Fly Ash Using Extended Elutriate Tests, A. J. Bednar, M. A. Chappell, J. M. Seiter, J. K. Stanley, D. E. Averett, W. T. Jones, B. A. Pettway, A. J. Kennedy, S. H. Hendrix, J. A. Steevens

United States Army: Publications

A storage pond dike failure occurred at the Tennessee Valley Authority Kingston Fossil Plant that resulted in the release of over 3.8 million cubic meters (5 million cubic yards) of fly ash. Approximately half of this material deposited in the main channel of the Emory River, 3.5 km upstream of the confluence of the Emory and Clinch Rivers, Tennessee, USA. Remediation efforts to date have focused on targeted removal of material from the channel through hydraulic dredging, as well as mechanical excavation in some areas. The agitation of the submerged fly ash during hydraulic dredging introduces river water into the …

Study Of Strawberry Flavored Milk Under Pulsed Electric Field Processing, Daniela Bermúdez-Aguirre, Jaime A. Yáñez, C. Patrick Dunne, Neal M. Davies, Gustavo V. Barbosa-Cánovas

United States Army: Publications

Few studies exist on flavored milk processed by pulsed electric fields (PEF). The main concern is product stability. This study aimed to analyze the degradation of coloring agent Allura Red in strawberry milk under PEF. Four systems were tested containing Allura Red: two commercial milks and two model systems. PEF conditions were 40 kV/cm, 48 pulses (2.5 μs), and 55 °C; coloring agent was quantified via RP-HPLC. After processing, only minor changes were observed in color, Allura Red concentration, and pH. During storage (32 d) at refrigerated conditions (4 °C) commercial samples maintained pH above 6. Model systems dropped below …

Nontuberculous Mycobacterium Infection In A Burn Icu Patient, Joseph M. Boyer, Peter J. Blatz, Kevin S. Akers, Jason F. Okulicz, Kevin K. Chung, Evan M. Rentz, Duane R. Hospenthal, Clinton K. Murray

United States Army: Publications

Infection is a leading cause of mortality in burn patients, typically due to bacterial pathogens such as Staphylococcus aureus and Pseudomonas aeruginosa, less commonly fungi, and possibly viruses. In non-burn patients with underlying pulmonary or cutaneous disease, nontuberculous mycobacteria (NTM) have become an increasingly recognized cause of infection, especially in patients who are immunocompromised. Patients with severe burns might have higher rates of NTM infections due to inherent risks associated with the burn injury: compromised skin integrity, immunocompromised state, inhalation injury, and frequent use of indwelling vascular catheters. To date there have been no reports describing the incidence of …

Acute Caffeine Consumption Enhances The Executive Control Of Visual Attention In Habitual Consumers, Tad T. Brunyé, Caroline R. Mahoney, Harris R. Lieberman, Grace E. Giles, Holly A. Taylor

United States Army: Publications

Recent work suggests that a dose of 200–400 mg caffeine can enhance both vigilance and the executive control of visual attention in individuals with low caffeine consumption profiles. The present study seeks to determine whether individuals with relatively high caffeine consumption profiles would show similar advantages. To this end, we examined the effects of four caffeine doses (0 mg, 100 mg, 200 mg, 400 mg) on low- and high-level visual attention in individuals with high consumption profiles (n = 36), in a double-blind study using a repeated measures design. Results from the Attention Network Test indicated that caffeine enhanced both …

The Effects Of Bleedarrest, Celox, And Traumadex On Hemorrhage Control In A Porcine Model, Brian Gegel, James Burgert, Brian Cooley, Jacob Macgregor, Jules Myers, Sean Calder, Ralph Luellen, Michael Loughren, Don Johnson

United States Army: Publications

Background

Hemorrhage is the second leading cause of death in civilian trauma and the leading cause of preventable death in military trauma. The purpose
of this study was to examine the effectiveness of three hemostatic agents: BleedArrest, TraumaDex, and Celox.

Materials and Methods

This was a prospective, experimental study using male Yorkshire swine. The pigs (n = 5 per group) were randomly assigned to one of the following: BleedArrest, TraumaDex, Celox, or control. To simulate a trauma injury, the investigators generated a complex groin injury with transection of the femoral artery and vein in all pigs. After 1 min of …

Inflammatory Effects Of Inhaled Sulfur Mustard In Rat Lung, Rama Malaviya, Vasanthi R. Sunil, Jessica Cervelli, Dana R. Anderson, Wesley W. Holmes, Michele L. Conti, Ronald E. Gordon, Jeffrey D. Laskin, Debra L. Laskin

United States Army: Publications

Inhalation of sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung damage, is a significant threat to both military and civilian populations. The mechanisms mediating its cytotoxic effects are unknown and were investigated in the present studies. Male rats Crl:CD(SD) were anesthetized, and then intratracheally intubated and exposed to 0.7–1.4 mg/kg SM by vapor inhalation. Animals were euthanized 6, 24, 48 h or 7 days post-exposure and bronchoalveolar lavage fluid (BAL) and lung tissue collected. Exposure of rats to SM resulted in rapid pulmonary toxicity, including focal ulceration and detachment of the trachea and bronchial epithelia from underlying …

Characterization Of Silver Nanoparticles Using Flow-Field Flow Fractionation Interfaced To Inductively Coupled Plasma Mass Spectrometry, A. R. Poda, A. J. Bednar, A. Harmon, M. Hull, D. M. Mitrano, J. F. Ranville, J. Steevens

United States Army: Publications

The ability to detect and identify the physiochemical form of contaminants in the environment is important for degradation, fate and transport, and toxicity studies. This is particularly true of nanomaterials that exist as discrete particles rather than dissolved or sorbed contaminant molecules in the environment. Nanoparticles will tend to agglomerate or dissolve, based on solution chemistry, which will drastically affect their environmental properties. The current study investigates the use of field flow fractionation (FFF) interfaced to inductively coupled plasma-mass spectrometry(ICPMS) as a sensitive and selective method for detection and characterization of silver nanoparticles. Transmission electron microscopy (TEM) is used to …

Raman Spectroscopic Modeling Of T- Lymphocyte Activation And Detection Of Acute Renal Allograft Rejection, Kristian L. Brown

Wayne State University Dissertations

ABSTRACT

RAMAN SPECTROSCOPIC MODELING OF T-LYMPHOCYTE ACTIVATION AND DETECTION OF ACUTE RENAL ALLOGRAFT REJECTION

By

KRISTIAN L. BROWN

2010

Advisor: Gregory Auner, PhD

Major: Biomedical Engineering

Degree: Doctor of Philosophy

Despite the advances made in the area of kidney transplantation, the disparity between the demand and available donated organs remains a dominant and unresolved issue. Given the paucity of available renal allografts the preservation of existing grafts is vital. One factor that has negatively impacted renal allograft survival is acute rejection (AR). Traditionally, kidney transplant centers have used elevations in serum creatinine as a screening tool for detecting AR. However, …

Identification Of Neuroblastoma And Its Prognostic Markers Using Raman Spectroscopy, Rachel Kast

Wayne State University Dissertations

Introduction: Neuroblastoma is the most common cancer of infancy. It is one of several peripheral nervous system tumors, including ganglioneuroma, peripheral nerve sheath tumor, and pheochromocytoma. It is commonly situated on the adrenal gland. It displays similar histology to other small round blue cell tumors, including non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma. One method of judging neuroblastoma aggressiveness uses tumor histology factors, including mitosis-karyorrhexis index, Schwannian stromal development, degree of differentiation, and patient age. Tumor aggressiveness can also be judged based on the amplification of certain genes, including MYCN. Raman spectroscopy is a physics-based method which identifies the biochemical …

Effects From Filtration, Capping Agents, And Presence/Absence Of Food On The Toxicity Of Silver Nanoparticles To Daphnia Magna, H. Joel Allen, Christopher A. Impellitteri, Dana A. Macke, J. Lee Heckman, Helen C. Poynton, James M. Lazorchak, Shekar Govindaswamy, Deborah L. Roose, Mallikarjuna N. Nadagouda

United States Environmental Protection Agency: Publications

Relatively little is known about the behavior and toxicity of nanoparticles in the environment. Objectives of work presented here include establishing the toxicity of a variety of silver nanoparticles (AgNPs) to Daphnia magna neonates, assessing the applicability of a commonly used bioassay for testing AgNPs, and determining the advantages and disadvantages of multiple characterization techniques for AgNPs in simple aquatic systems. Daphnia magna were exposed to a silver nitrate solution and AgNPs suspensions including commercially available AgNPs (uncoated and coated), and laboratory-synthesized AgNPs (coated with coffee or citrate). The nanoparticle suspensions were analyzed for silver concentration (microwave acid digestions), size …

Persistent Organic Pollutants In Fish Tissue In The Mid-Continental Great Rivers Of The United States, Karen A. Blocksom, David M. Walters, Terri M. Jicha, James M. Lazorchak, Theodore R. Angradi, David W. Bolgrien

United States Environmental Protection Agency: Publications

Great rivers of the central United States (Upper Mississippi, Missouri, and Ohio rivers) are valuable economic and cultural resources, yet until recently their ecological condition has not been well quantified. In 2004– 2005, as part of the Environmental Monitoring and Assessment Program for Great River Ecosystems (EMAPGRE), we measured legacy organochlorines (OCs) (pesticides and polychlorinated biphenyls, PCBs) and emerging compounds (polybrominated diphenyl ethers, PBDEs) in whole fish to estimate human and wildlife exposure risks from fish consumption. PCBs, PBDEs, chlordane, dieldrin and dichlorodiphenyltrichloroethane (DDT) were detected in most samples across all rivers, and hexachlorobenzene was detected in most Ohio River …

Biological Opinion On The Operation Of The Missouri River Main Stem System, Operation And Maintenance Of The Missouri River Bank Stabilization And Navigation Project, And Operation Of The Kansas River Reservoir System

United States Army Corps of Engineers, Omaha District

This Annual Report summarizes implementation efforts in response to the Biological Opinion on the Operation of the Missouri River Main Stem System, Operation and Maintenance of the Missouri River Bank Stabilization and Navigation Project, and Operation of the Kansas River Reservoir System. The document improves upon the previous annual Biological Opinion (BiOp) compliance reports by incorporating:

• The first combined U.S. Fish and Wildlife (USFWS) and U.S. Army Corps of Engineers (Corps) report documenting recovery efforts on the Missouri River satisfying reporting requirements of the 2003 Amended BiOp on the Operation of the Missouri River Main Stem System (System), Operation …

Performance Measures Of Warm Asphalt Mixtures For Safe And Reliable Freight Transportation, Hosin "David" Lee Ph.D., P.E., Yongjoo "Thomas" Kim

Mid-America Transportation Center: Final Reports and Technical Briefs

Warm mix asphalt (WMA) is an emerging technology that can allow asphalt to flow at a lower temperature for mixing, placing and compaction. The advantages of WMA include reduced fuel consumption, less carbon dioxide emission, longer paving season, longer hauling distance, reduced oxidation of asphalt, early opening to traffic and a better working environment in the field. In the United States, WMA has become popular in recent years. However, to provide a safe and reliable highway for heavier truck traffic with a high tire pressure, WMA mixtures must meet requirements for strength, stiffness, rutting, and moisture resistance.

WMA mixtures with …

Improving Freight Fire Safety: Assessment Of The Effectiveness Of Mist-Controlling Additives In Mitigating Crash-Induced Diesel Fires, Albert Ratner Ph.D.

Mid-America Transportation Center: Final Reports and Technical Briefs

Adding long chained polymers to diesel has been proposed as a method to prevent crash fires by arresting the break-up of diesel fuel into a fine mist in transportation related accidents. The effect of such additives on the flow properties of diesel was investigated by studying the impact of poly-butadiene and diesel blend drops on a solid surface using high speed imaging. The addition of the polymer imparted shear-thinning behavior to diesel, and the base viscosities increased rapidly with polymer concentration. Four concentrations of the polymer were tested at three different impact speeds under atmospheric pressure. Maximum spread factors and …

Proposed Implementation Of A Cottonwood Management Plan Along Six Priority Segments Of The Missouri River

United States Army Corps of Engineers, Omaha District

The Missouri River originates in the Rocky Mountains of south-central Montana and flows approximately 2,341 miles through seven states, ending at its confluence with the Mississippi River near St. Louis, Missouri. The plains cottonwood (Populus deltoides) was once the dominant floodplain vegetation in the Missouri River ecosystem (Corps 2006a). Natural cottonwood regeneration has largely ceased along the Missouri River following the construction of the Missouri River Mainstem Reservoir System (System) and Bank Stabilization and Navigation Project (BSNP). The reduction in the number of young cottonwoods to replace older cottonwoods concerns biologists because a variety of plant and wildlife …

Climate Change And Sea Level Rise Initiative (Ccslri), Larry P. Atkinson

CCSLRI Brochures

Brochure of the Old Dominion University Climate Change and Sea Level Rise Initiative (CCSLRI)

What About The Children? Benjamin And Arendt: On Education, Work, And The Political, Jules Simon

Departmental Papers (Philosophy)

This article is a rough draft of an article that I contributed to an edited volume of articles dealing with progressive education theory. I reflect on articles that Hannah Arendt and Walter Benjamin wrote that deal with educational reform and innovation, both political in nature.

Development Of An Accident Model For Construction Industry, Hoda Alavi

Civil Engineering Theses - Archive

Safety has always been a persistent problem in the construction industry. Construction accidents are a major concern for the construction industry and the researchers. In spite of the role of many construction accident causation models in understanding the accident process, none adequately explain the underlying reasons for construction accidents because of their dynamic nature.To overcome this restriction a new advancement in understanding construction accidents has been proposed by Howell et al (2002) based on the work of Rasmussen (1997). The model recognizes that organizational and individual forces push workers in to hazardous conditions. These forces overcome efforts to impose safe …

Capacitive Strain Sensors For Measurement Of Large Strain For Structural Health Monitoring, Clement Jacob

Electrical Engineering Theses - Archive

Structural health monitoring (SHM) is increasingly used to replace time based management, with a more efficient Condition Based Maintenance (CBM). The traditional scheme of scheduling down time for aircraft inspection or periodic evaluation of civil infrastructure costs millions of dollars in maintenance due to either downtime or lack of timely maintenance. SHM involves periodic, real time sampling and analysis of signals, from onboard sensors like accelerometer, pressure, strain or acoustic sensors to determine the condition of the structure. This can be used to carry out immediate repairs as well as predict failure. We report the development of a new high …

High School Bridge Program: A Multidisciplinary Stem Research Program, Jiang Zhe, Dennis Doverspike, Julie Zhao, Paul C. Lam, Craig C. Menzemer

Mechanical Engineering Faculty Research

A Science, Technology, Engineering and Math (STEM) summer Bridge Program was developed for high school students. The program was designed to encourage students to consider choosing an engineering major in college and to explore STEM as a future career. This was accomplished through a 10-week program involving multidisciplinary research activities. The participants in the program included 33 high school students. Among former participants in position to make a choice in terms of attending college, 100% had chosen to continue on in college, and 86% had chosen to major in a STEM area. The results indicated that that the program had …

Risk And System-Of-Systems: Toward A Unified Concept, C. Ariel Pinto, Michael K. Mcshane, Rani Kady

Engineering Management & Systems Engineering Faculty Publications

The scope of this paper is the survey of both fundamental and most recent publications in system-of-systems, business and insurance, as well as risk analysis, modeling, and management for the purpose of better describing the concept of risk in recognition of emergence and complexity which characterizes many systems within the concern of engineering and business managers. The ultimate goal is to provide engineering and business managers the necessary perspective on the concept of risk and in its management for the next generation of sustainable systems - including various descriptions of risk and discussion of the relevance of properties of system-of-systems …

Wi-Fi Localization Using Rssi Fingerprinting, Michael Quan, Eduardo Navarro, Benjamin Peuker

Computer Engineering

Wireless Local Area Networks using Wi-Fi is becoming more and more ubiquitous. As such, they provide a potential pre-built infrastructure for small area localization. This project serves as a proof of concept for a playground child tracking system to be deployed at Cal Poly's Child Development Playground Lab. The two main options for doing Wi-Fi localization are triangulation and fingerprinting. Triangulation involves mapping signal strength as a function of distance while fingerprinting creates a probability distribution of signal strengths at a given location and uses a map of these distributions to predict a location given signal strength samples. The triangulation …

Distributed Reasoning With El++ Using Mapreduce, Frederick Maier, Raghava Mutharaju, Pascal Hitzler

Computer Science and Engineering Faculty Publications

It has recently been shown that the MapReduce framework for distributed computation can be used effectively for large-scale RDF Schema reasoning, computing the deductive closure of over a billion RDF triples within a reasonable time. Later work has carried this approach over to OWL Horst. In this paper, we provide a MapReduce algorithm for classifying knowledge bases in the description logic EL⁺⁺, which is essentially the OWL 2 profile OWL 2 EL. The traditional EL⁺⁺ classification algorithm is recast into a form compatible with MapReduce, and it is shown how the revised algorithm can be realized within …

Partitioning Of Perfluorooctanoate Into Phosphatidylcholine Bilayers Is Chain Length-Independent, Wei Xie, Geoffrey D. Bothun, Hans-Joachim Lehmler

Chemical, Biomolecular, and Materials Engineering Faculty Publications

The chain length dependence of the interaction of PFOA, a persistent environmental contaminant, with dimyristoyl- (DMPC), dipalmitoyl- (DPPC) and distearoylphosphatidylcholine (DSPC) was investigated using steady-state fluorescence anisotropy spectroscopy, differential scanning calorimetry (DSC) and dynamic light scattering (DLS). PFOA caused a linear depression of the main phase transition temperature T_m while increasing the width of the phase transition of all three phosphatidylcholines. Although PFOA's effect on T_m and the transition width decreased in the order DMPC > DPPC > DSPC, its relative effect on the phase behavior was largely independent of the phosphatidylcholine. PFOA caused swelling of DMPC but not DPPC …

Development Of A Preliminary Cost Estimation Method For Water Treatment Plants, Jwala Raj Sharma

Civil Engineering Theses - Archive

Reliable cost estimates for construction, and operation and maintenance (O&M) of water treatment plants are essential for their project planning and design. During the planning phases of the project, preliminary cost estimates are developed for major project components, and for screening of alternatives.Construction and O&M cost curves are widely used for developing preliminary cost estimates. This method is time consuming and there is possibility of human errors. Therefore, for this thesis, construction, and O&M cost equations were developed considering historical cost data for different unit operations and processes involved in a water treatment plant. These equations were developed from historical …

Quality Indicators For Engineering And Technology Education, Michael Dyrenfurth, Mike Murphy, Gary Bertoline

Conference papers

In recent years the development and use of university rankings, comparisons, and/or league tables has become popular and several methodologies are now frequently used to provide a comparative ranking of universities. These rankings are often based on research and publication activity and also not uncommonly focus on indicators that can be measured rather than those that should be measured. Further, the indicators are generally examined for the university as a whole rather than for university divisions, departments or programs. Implicit also is that placement in the rankings is indicative of quality. This paper provides an overview of the methodologies used …

Ab-10-018: The Effects Of Noise From Building Mechanical Systems With Tonal Components On Human Performance And Perception (1322-Rp), Erica E. Ryherd, Lily M. Wang

Durham School of Architectural Engineering and Construction: Faculty Publications

This study investigated the effects of noise from building mechanical systems with tonal components on human task performance and perception. Six different noise conditions based on in-situ measurements were reproduced in an office-like setting; all were set to approximately the same sound level (47 dBA) but could have one particular tonal frequency (120 Hz, 235 Hz, or 595 Hz) at one of two tonal prominence ratios (5 or 9). Thirty participants were asked to complete typing, grammatical reasoning, and math tasks plus subjective questionnaires, while being exposed for approximately 1 hour to each noise condition. Results show that the noise …

Transgenic Rat Model Of Neurodegeneration Caused By Mutation In The Tdp Gene, Hongxia Zhou, Cao Huang, Han Chen, Dian Wang, Carlisle P. Landel, Pedro Yuxing Xia, Robert Bowser, Yong-Jian Liu, Xu Gang Xia

Nebraska Center for Biotechnology: Faculty and Staff Publications

TDP-43 proteinopathies have been observed in a wide range of neurodegenerative diseases. Mutations in the gene encoding TDP-43 (i.e., TDP) have been identified in amyotrophic lateral sclerosis (ALS) and in frontotemporal lobe degeneration associated with motor neuron disease. To study the consequences of TDP mutation in an intact system, we created transgenic rats expressing normal human TDP or a mutant form of human TDP with a M337V substitution. Overexpression of mutant, but not normal, TDP caused widespread neurodegeneration that predominantly affected the motor system. TDP mutation reproduced ALS phenotypes in transgenic rats, as seen by progressive degeneration of motor neurons …

Dual-Stage Sugar Substitution In Strawberries With A Stevia-Based Sweetener, Juan Garcia-Noguera, Curtis L. Weller, Francisca I. P. Oliveira, Sueli Rodrigues, Fabiano A. N. Fernandes

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The present study introduces and analyzes a new process denominated dual-stage sugar substitution (D3S). This process aims to induce sugar substitution in strawberries. In a first stage, high-calorie sugars (sucrose, fructose and glucose) are partially removed from the fruit samples and in a second stage, low-calorie sugar (stevioside and rebaudioside) is incorporated to the fruit to maintain its sweetness. The process was evaluated by studying the use of ultrasound application in one or both stages of the D3S process. Best performance of the process was obtained by subjecting the fruit samples to ultrasound in the sugar removal stage followed by …