Digital Commons Network^™

Electro-Gene Transfer To Skin Using A Noninvasive Multielectrode Array, Siqi Guo, Amy Donate, Gaurav Basu, Cathryn Lundberg, Loree Heller, Richard Heller

Bioelectrics Publications

Because of its large surface area and easy access for both delivery and monitoring, the skin is an attractive target for gene therapy for cutaneous diseases, vaccinations and several metabolic disorders. The critical factors for DNA delivery to the skin by electroporation (EP) are effective expression levels and minimal or no tissue damage. Here, we evaluated the non-invasive multielectrode array (MEA) for gene electrotransfer. For these studies we utilized a guinea pig model, which has been shown to have a similar thickness and structure to human skin. Our results demonstrate significantly increased gene expression 2 to 3 logs above injection …

An Occupational Analysis Of Prepress In The Des Moines And Eastern Iowa Regions, Lee John Geisinger

Dissertations and Theses @ UNI

It is important that educators use a relevant, up-to-date curriculum when educating on a specific occupation. Job task analysis is an effective way for educators to understand an occupation and provide students with valuable information. This study analyzed prepress technicians' duties and tasks.

This research used the occupational analysis method called the DACUM (Developing a Curriculum) process. The DACUM process uses an expert worker panel to identify the duties and tasks of an occupation. This study found that there are 9 duties and 55 tasks for a prepress technician. After identifying the duties and tasks, the study confirmed those duties …

Command And Control For Boring System, W. A. Berger, J. A. Carter, Marian Mazurkiewicz, R. M. Pell, R. A. Spalletta

Mining Engineering Faculty Research & Creative Works

A system having a number of land units [100, 4000, 5000] is disclosed which operates to efficiently find and create boreholes [5] to one or more underground targets [1]. Each of the land units [100, 4000, 5000] may be remotely controlled from a central command unit [6000]. The land unit also may be self-controlled, or partially controlled by the central command unit [6000]. The system [10] is reconfigurable to reallocate tasks to functional land units [100, 4000, 5000] which were originally allocated to land units which have been destroyed and are now non-functional.

Stability Analysis Of Anchored Rock Slopes Against Plane Failure Subjected To Surcharge And Seismic Loads, Md M. Hossain

Theses: Doctorates and Masters

The stability analysis of rock slopes has been a challenging task for engineers

because the rock mass constituting the slope often has discontinuities in various

forms, resulting in different types of slope failures. The plane failure is one of the

rock slope failures observed in field situations when the discontinuity is in the form

of joint planes. There are several parameters including surcharge and seismic loads

that govern the stability of the rock slope against plane failure in field projects. The

limit equilibrium approach for the estimation of the factor of safety of the rock slope

against plane failure has …

Ultra-Abrupt Tapered Fiber Mach-Zehnder Interferometer Sensors, B. Li, J. Lan, W. Sumei, L. Zhou, Hai Xiao, Hai-Lung Tsai

Electrical and Computer Engineering Faculty Research & Creative Works

A fiber inline Mach-Zehnder interferometer (MZI) consisting of ultra-abrupt fiber tapers was fabricated through a new fusion-splicing method. By fusion-splicing, the taper diameter-length ratio is around 1:1, which is much greater than those (1:10) made by stretching. The proposed fabrication method is very low cost, 1/20-1/50 of those of LPFG pair MZI sensors. The fabricated MZIs are applied to measure refractive index, temperature and rotation angle changes. The temperature sensitivity of the MZI at a length of 30 mm is 0.061 nm/°C from 30-350 °C. The proposed MZI is also used to measure rotation angles ranging from 0° to 0.55°; …

Relativistic Red-Black Trees, Philip William Howard, Jonathan Walpole

Computer Science Faculty Publications and Presentations

Operating system performance and scalability on sharedmemory many-core systems depends critically on efficient access to shared data structures. Scalability has proven difficult to achieve for many data structures. In this paper we present a novel and highly scalable concurrent red-black tree. Red-black trees are widely used in operating systems, but typically exhibit poor scalability. Our red-black tree has linear read scalability, uncontended read performance that is at least 25% faster than other known approaches, and deterministic lookup times for a given tree size, making it suitable for realtime applications.

A Study To Determine The Influence Of Workload On Nursing Personnel, Supreeta G. Amin

Dissertations

The alarming number of adverse medical events and associated costs have placed immense importance toward the safety and health of both patients and medical personnel. A shrinking nurse workforce, an aging patient and nursing population coupled with a mismatch between hospital demands and the available nursing staff have created a situation detrimental to both patient and nursing personnel. Long working hours, working more than one job, low staffing ratios, high patient acuity, minimal social support, low experience level, complicated equipment, complex procedures and varying workload are some factors that may have a negative impact on the quality of care provided …

Leach-Sm: A Protocol For Extending Wireless Sensor Network Lifetime By Management Of Spare Nodes, Bilal Abu Bakr

Dissertations

Operational lifetime of a wireless sensor network (WSN) depends on its energy resources. Significant improvement of WSN lifetime can be achieved by adding spare sensor nodes to WSN. Spares are ready to be switched on when any primary (a node that is not a spare) exhausts its energy. A spare replacing a primary becomes a primary itself.

The LEACH-SM protocol (Low-Energy Adaptive Clustering Hierarchy with Spare Management) proposed by us is a modification of the prominent LEACH protocol. LEACH extends WSN lifetime via rotation of cluster heads but allows for inefficiencies due to redundant sensing target coverage. There are two …

Anti-Microbial Self-Assembling "Click" Monolayers Utilizing Silver Nanoparticles For Indwelling Medical Devices, Emily Ann Hodges

LSU Master's Theses

The objective of this study was to synthesize and characterize antimicrobial, silver nanoparticles based self-assembling monolayer coatings, for use on chronic indwelling medical devices. The coatings are comprised of novel biomass mediated silver nano particles (SNP) that are biocompatible, highly concentrated, highly pure, cost-effective, polydispersed and compatible for use with existing chronic indwelling medical devices. The HPC SNPs were functionalized with an azide functional group and covalently bound to titanium substrates via ¨Dclick¡¬ chemistry.

Investigation Of The Hygroscopic And Morphological Properties Of Atmospheric Aerosols, Laura Cook

Master’s Theses

The first objective of this thesis was to examine the hygroscopic and morphological nature of various substances through the use of an Environmental Scanning Electron Microscope (ESEM). The hygroscopic growth and changes in morphology for pure-component aerosols were studied for particles greater than 2 µm in size. Hygroscopic growth was observed through changes in relative humidity (RH) and hygroscopic growth curves were created. The second objective of this thesis, the hygroscopic growth of multi-component aerosol mixtures, was studied using Hygroscopic Tandem Differential Mobility Analysis(HTDMA). The size distribution for an aerosol stream was determined before and after the stream was subjected …

A Study Of High Solids Anaerobic Digestion Of Bucknell University Food Waste Followed By Aerobic Curing, Margaret Drennan

Master’s Theses

Anaerobic digestion of food scraps has the potential to accomplish waste minimization, energy production, and compost or humus production. At Bucknell University, removal of food scraps from the waste stream could reduce municipal solid waste transportation costs and landfill tipping fees, and provide methane and humus for use on campus. To determine the suitability of food waste produced at Bucknell for high-solids anaerobic digestion (HSAD), a year-long characterization study was conducted. Physical and chemical properties, waste biodegradability, and annual production of biodegradable waste were assessed. Bucknell University food and landscape waste was digested at pilot-scale for over a year to …

Corrosion Characteristics And Mechanical Properties Of Aluminum Coatings Applied By The Cold Spray Process, Ben Bouffard

Master’s Theses

Aluminum coatings were applied to 2024-T3 and 7075-T6 aluminum alloys via the Cold Spray process. The coatings were applied to substrateswith various surface preparation and Cold Spray carrier gas combinations. Some samples were coated with an additional sealant with and without a chromate conversion layer. An exhaustive corrosion analysis was then performed which utilized a number of long termand accelerated tests in order to characterize the corrosion protection of the coatings.

Emerging M&S Application In Risk Management, C. Ariel Pinto, Andreas Tolk, Michael Mcshane

Engineering Management & Systems Engineering Faculty Publications

There has been compelling signs of the great potential of building further synergy with academics, researchers, and industry practitioners from the areas of Modeling and Simulation (M&S) managing risk events. This paper provides an introduction to risk management and how M&S has permeated the risk management process. The trend has been to harness the advantages of M&S tools and techniques in terms of efficiency and effectiveness in managing risks. However, the more important contribution of M&S may be in how it provides a way for specialists in various disciplines or industries interact to manage risks that require multi-disciplinary approach. This …

Evaluating Algal Growth At Different Temperatures, Keelin Owen Cassidy

Theses and Dissertations--Biosystems and Agricultural Engineering

In recent years, there has been a concern for the amount of carbon dioxide released into the atmosphere and how it will be captured. One way to capture carbon dioxide is with algae. In this study, algae's growth was measured at different temperatures. The first part of the study was to grow Scenedesmus and Chlorella with M8 or urea growth media at a temperature of 25, 30 or 35ºC. It was found that 30ºC had the best growth rates for both algae. The second part studied Scenedesmus growth with urea, more in-depth, and found the optimum growth temperature to be …

An Advanced Controller For A Semi-Active Wheelchair Suspension, David J. Smith

Master's Theses

An Advanced Controller for a Semi-Active Wheelchair Suspension was designed, built and tested.  The suspension consisted of a Goodyear 1S3-011 air spring, IQ Valves high speed proportional solenoid valve, and a custom made accumulator.  Several controller designs specific to semi-active suspensions were designed and tested.  The controllers investigated were skyhook, acceleration driven damping, and a combined control law employing both a dual and single sensor version.  The implementation of skyhook control suffered performance degradation from the idealization due to particular elements of hardware, however acceleration driven damping showed a marked and statistically significant improvement over skyhook control, in hardware, by …

Performance Of Control Room Operators In Alarm Management, Dileep Buddaraju

LSU Master's Theses

Pipelines transport millions of barrels of petroleum products every day. These systems have significant safety concerns. The BP oil spill in the Gulf of Mexico, while concerned with oil and gas extraction rather than distribution, shares many of the same safety and reliability issues as distribution systems, and demonstrates the significant potential for major disasters in the pipeline industry. In this work, a research study is being conducted to further understanding of the role of operators in the management of alarm systems and to measure the performance of operators in handling abnormal situations like pressure loss, liquid inflow/outflow variation and …

Screening Of Tar Cracking Catalysts For Syngas Produced By Biomass Gasification, Bijeet Mukherjee

LSU Master's Theses

The gasification of biomass produces tars and particulates. These tars and particulates create problems in the gasification systems. Tars condense on surfaces at lower temperatures, such as exit pipes and on particulate filters, leading to blockages and clogged filters. Tars also have varied impacts on other downstream processes. Due to these reasons, syngas containing significant concentrations of tars cannot be used in internal combustion engines. Thus the processes through which tars can be removed have been subject to considerable research. The objective of this research was to identify the best catalyst for for down-draft gasifiers, including the LSU AgCenter down-draft …

Smart Access Control System With Behavioral Profiling And Dynamic Pin Concept, Lohit Penubaku

LSU Master's Theses

Since ancient time, an access control device has been used for securing valuable properties as well as lives from threatening peoples. The most representative security device is Lock/Key. Recently, those security device technologies have been improved tremendously and provided various types of security methods. Nevertheless, these methods are not individually perfect to provide optimal security so that in recent years many such methods have been combined and used together to provide the required level of security. However, such combination can enhance security for limited number of users only but very difficult to provide scalable security with the number of users …

Assymmetry In Distribution Systems: Causes, Harmful Effects And Remedies, Isaac Plummer

LSU Master's Theses

ABSTRACT: Current and voltage asymmetry denigrates the power system performance. The current asymmetry reduces efficiency, productivity and profits at the generation, transmission and distribution of electric energy. Voltage asymmetry reduces efficiency, productivity and profits at the consumption/utilization level. There are a lot of conference and journal papers on the subject of voltage and current asymmetry, however, the information is scattered over a large number of journals and conferences and published over several years. Therefore, the thesis provides a comprehensive compilation of all possible published information on current and voltage asymmetry in the electrical power systems. Published information on sources of …

Development Of A Total Nutrient Treatment System For Alligator And Dairy Parlor Wastewater Using Hydrated Lime And Organic Bacterial Growth Media, Troy Francis Davis

LSU Master's Theses

Over application of phosphorus and the loss of ammonia-nitrogen to runoff and volatilization have resulted in the buildup of phosphorus in agricultural top soils around the world, and especially in the United States. Over the past few decades, raising livestock has trended towards the development of the Confined Animal Feeding Operations (CAFO’s) which produce large volumes of wastes that need to be treated before being land applied. Nutrient treatment systems have typically focused on one nutrient singularly: either nitrogen or phosphorus. In order to develop a total nutrient system a phosphorus and nitrogen system had to be developed and evaluated …

Developing A Tool To Characterize The Ultradian Rhythm In Diploid Saccharomyces Cervisiae Using The Reporter Gene Green Fluorescent Protein, Imran Chiragh

LSU Master's Theses

Biological rhythms control many temporal behaviors of organism, such as the sleep cycle, hearts rhythms, seasonal animal migrations etc. Understanding these rhythms would provide insight into the temporal process of living organisms. Saccharomyces cerevisiae, a budding yeast, is an ideal model organism to study biological rhythms in eukaryotic cells because of its sequenced genome and discerned processes. By characterizing the biological rhythm in budding yeast, insight can be gained into more complex organisms. Previous studies have exhibited oscillatory behavior of oxygen consumption and determined that deletion of the GTS1 gene dissipates this rhythm. However, to further understand the specific behavior …

An Integrated Computer-Aided Robotic System For Dental Implantation, Xiaoyan Sun, Yongki Yoon, Jiang Li, Frederic D. Mckenzie

Electrical & Computer Engineering Faculty Publications

This paper describes an integrated system for dental implantation including both preoperative planning utilizing computer-aided technology and automatic robot operation during the intra-operative stage. A novel two-step registration procedure was applied for transforming the preoperative plan to the operation of the robot, with the help of a Coordinate Measurement Machine (CMM). Experiments with a patient-specific phantom were carried out to evaluate the registration error for both position and orientation. After adopting several improvements, registration accuracy of the system was significantly improved. Sub-millimeter accuracy with the Target Registration Errors (TREs) of 0.38±0.16 mm (N=5) was achieved. The target orientation errors after …

Direct Forcing And Heating Immersed Boundary- Lattice Boltzmann Method For Arterial Wall Thermography, Oluyinka Olugbenga Bamiro

Dissertations

Vulnerable atherosclerotic plaques have high probability of rupture and are characterized by non-homogenous temperature along the arterial wall. The nonhomogeneous temperature is attributed to the accumulation of heat releasing inflammatory cells in the arterial wall. Rupture of the vulnerable plaque can lead to acute coronary syndrome and sudden cardiac death. Arterial wall thermography (AWT) can be applied to detect the presence of temperature hot spots along the arterial wall by using temperature measurement devices and provide an early detection of a vulnerable atherosclerotic plaque. AWT, however, is invasive in nature.

Computational fluid and heat transport models provide a more efficient …

Ductile Mode Material Removal Of Ceramics And Semiconductors, Deepak Ravindra

Dissertations

Ceramics and semiconductors are hard, strong, inert and lightweight. They also have good optical properties, wide energy bandgap and high maximum current density. This combination of properties makes them ideal candidates for tribological, semiconductor, MEMS and optoelectronic applications respectively. Manufacturing these materials without causing surface and subsurface damage is extremely challenging due to their high hardness, brittle characteristics and poor machinability. However, ductile regime machining of these materials is possible due to the high-pressure phase transformation occurring in the material caused by the high compressive stresses induced by the single point diamond tool tip. In this study, to further augment …

Implementation Of A Wireless Sensor Network With Ez430-Rf2500 Development Tools And Msp430fg4618/F2013 Experimenter Boards From Texas Instruments, Lu De Yang

LSU Master's Theses

Wireless sensor networks have found a great deal of applications in diverse areas. Recent interest has been focused on low-power feature of the sensor nodes because the power consumption is always an issue for wireless sensor nodes which are supplied from the batteries. The eZ430RF2500 Development Tool and MSP430FG4618/F2013 Experimenter Board from Texas Instruments have integrated MSP430 family of ultralow-power microcontrollers and CC2500 low-power wireless RF transceivers which are suitable for low-power, low-cost wireless applications. In this thesis, the features of these TI devices are explored and a wireless sensor network is implemented with these devices. To implement the routing …

Foldable Substrates For Micro-Ultrasonic Transducers, Karthik Balasubramanian

LSU Master's Theses

Ultrasound has broad range of applications from underwater examination, nondestructive testing of materials and medical diagnosis and treatment. The ultrasonic transducer plays an vital role in determining the resolution, sensitivity, as well as other diagnostic capabilities of an ultrasonic imaging system. Current piezoelectric transducer which dominates the medical field has limited applications compared to the capacitive ultrasonic transducer. The capacitive transducer is easy to fabricate compared to the piezoelectric transducer. In this work, the fabrication of a foldable substrate for a capacitive ultrasonic transducer has been discussed. The foldable substrate was fabricated using an ultrathin silicon wafer which is 50 …

Extraction Of Electronic Evidence From Voip: Forensic Analysis Of A Virtual Hard Disk Vs Ram, David Irwin, Jill Slay, Arek Dadej, Malcolm Shore

Journal of Digital Forensics, Security and Law

The popularity of Voice over the Internet Protocol (VoIP) is increasing as the cost savings and ease of use is realised by a wide range of home and corporate users. However, the technology is also attractive to criminals. This is because VoIP is a global telephony service, in which it is difficult to verify the user’s identification. The security of placing such calls may also be appealing to criminals, as many implementations use strong encryption to secure both the voice payload as well as to control messages making monitoring such VoIP calls difficult since conventional methods such as wire-tapping is …

Nitrogen Oxides In The Firn Air At Summit, Greenland, Claudia Toro

Dissertations, Master's Theses and Master's Reports - Open

Measurements of NOx within the snowpack at Summit, Greenland were carried out from June 2008 to July 2010, using a novel system to sample firn air with minimal disruption of the snowpack. These long-term measurements were motivated by the need of improving the representation of air-snow interactions in global models. Results indicated that the NOx budget within the snowpack was on the order of 550 pptv as maximum, and was constituted primarily for NO2. NOx production was observed within the first 50 cm of the snowpack during the sunlight season between February and August. Presence of NOx at larger depths …

Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller

Mechanical and Aerospace Engineering Faculty Publications

The estimation of the centre of mass position in humans is usually based on biomechanical models developed from anthropometric tables. This method can potentially introduce errors in studies involving elderly people, since the ageing process is typically associated with a modification of the distribution of the body mass. In this paper, an alternative technique is proposed, and evaluated with an experimental study on 9 elderly volunteers. The technique is based on a virtual chain, identified from experimental data and locating the subject's centre of mass. Its configuration defines the location of the centre of mass, and is a function of …

Computational Investigation Of Particle Settling Effects On Inhaled Submicron Bioaerosol Deposition In The Human Lung, Mohammed Ali, Essam A. Ibrahim

Early Career Technical Journal (ECTJ)

Proceedings of the ASME Early Career Technical Conference, November 4-5, 2011. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia

pp. 1-5