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Using A Systemic Model Of Accident For Improving Innovative Technologies: Application And Limitations Of The Stamp Model To A Process For Treatment Of Contaminated Substances, Karim Hardy, Franck Guarnieri

Publications

This paper presents the STAMP accident model, based on systems theory, and describes its application in the context of risk prevention related to the remediation of contaminated materials. The implementation of the model is described, and results are presented both in methodological and technical terms.

A System Dynamics Model Of Pharmaceutical Opioids: Medical Use, Diversion, And Nonmedical Use, Teresa Schmidt, Wayne Wakeland, J. David Haddox

Complex Systems Faculty Publications and Presentations

A dramatic rise in the nonmedical of pharmaceutical opioids has presented the United States with a substantial public health problem. Nonmedical use of prescription pain relievers has become increasingly prevalent in the US over the last two decades, and diversion of medicines obtained by prescription is assumed to be a major source of supply for nonmedical opioid use. Policymakers striving to protect population health by ameliorating the adverse outcomes of nonmedical use of opioid analgesics could benefit from a systems-level model which reflects the complexity of the system and incorporates the full range of available data. To address this need, …

An Agent Based Framework For Sharing Personal Health Information, Ravi Kiran Kadaboina

Electrical and Computer Engineering ETDs

Over the past few years, several commercial vendors have started providing Personal Health Record (PHR) services. The PHR has been developed to be consumer-centric such that the consumer has all the control and not the health care provider. PHRs can be created, accessed and shared by a patient with authorized persons with the help of Health cloud based services provided by vendors like Microsoft HealthVault and Google Health. However, there is no formalized semantics that encourage users to share their data with prospective research facilities and drug companies. Creating an environment that allows users to manage how their personal health …

Examining The Relationships Among Injury Outcomes, Velocity And Grip Strength During Dynamic Platform Perturbation, Braden Cripe

Master's Theses (2009 -)

Studies examining the relationship between inputs and outputs for simulated models of dynamically perturbed horizontal platforms are scarce. Most of these scenarios include a standing operator with upper extremity grip, oftentimes subjected to lateral impulses, which may lead to occupant injury. While the detailed study of these collision scenarios is sparse, the prevalence of their application is great.

This thesis aims to identify how two input parameters, velocity change (ÄV) and grip strength, affect injury assessment reference values (IARVs). This is accomplished by using Mathematical Dynamic Modeling (MADYMO) software to simulate the scenarios defined by those inputs. In the simulation, …

Tools For Creating Wide-Field Views Of The Human Retina Using Optical Coherence Tomography, Ashavini M. Pavaskar

Master's Theses (2009 -)

Optical Coherence Tomography (OCT) has allowed in-vivo viewing of details of retinal layers like never before. With the development of spectral domain OCT (SD-OCT) details of nearly 2µm axial resolution and higher imaging speed have been reported. Nevertheless, a single volume scan of the retina is typically restricted to 6mm x 6mm in size. Having a larger field of view of the retina will definitely enhance the clinical utility of the OCT.

A tool was developed for creating wide-field thickness maps of the retina by combining the use of already available tools like i2k Retina (DualAlign, LLC, Clifton Park, NY) …

Using Modeling And Simulation To Improve Oral Health Services Delivery In Hampton Roads, Virginia, Mohammad J. Alzahrani

Health Services Research Dissertations

The purpose of this study is to examine the system performance in delivering oral health services in a public health district based on the Conceptual Framework to Measure Performance of the Public Health System (PHS). Using modeling and simulation, a predictive model based on the conceptual framework dimensions: mission, structural capacity, processes, and outcomes was developed to predict the performance of public health district in delivering oral health services.

This is a retrospective longitudinal study. The main objective of this study is to use a modeling and simulation approach to predict the performance of public health district dental clinic in …

Using Laser Scanning Cytometry To Investigate The Transport Of Nano-Scale Particles In Porous Media, Ryan May

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

The increased production of nanomaterials in recent years has been unprecedented. Given their potential toxicity, understanding the mechanisms controlling the transport of nanoparticles in the subsurface is important. In this study, a technique was developed for using a Laser Scanning Cytometer (LSC) to visualize and quantify the stable attachment of nano-scale particles. Experiments using three different size particles, 510 nm, 210 nm and 57 nm, in conjunction with a flow cell system containing saturated glass beads under varied injection duration, solution chemistry, Darcy velocity and solids content were performed. A technique for using the LSC data to develop spatial distributions …

An Enzymatic Treatment Of Soil-Bound Prions Effectively Inhibits Replication, Samuel Saunders, Jason C. Bartz, Kurt C. Vercauteren, Shannon L. Bartelt-Hunt

Department of Civil and Environmental Engineering: Faculty Publications

Chronic wasting disease (CWD) and scrapie can be transmitted through indirect environmental routes, possibly via soil, and a practical decontamination strategy for prion-contaminated soil is currently unavailable. In the laboratory, an enzymatic treatment under environmentally relevant conditions (22°C, pH 7.4) can degrade soil-bound PrPSc below the limits of Western blot detection. We developed and used a quantitative serial protein misfolding cyclic amplification (PMCA) protocol to characterize the amplification efficiency of treated soil samples relative to controls of known infectious titer. Our results suggest large (104- to >106-fold) decreases in soil-bound prion infectivity following enzyme treatment, demonstrating that a mild enzymatic …

A Water Distribution And Treatment Simulation For Testing Cyber Security Enhancements For Water Sector Scada Systems., Justin Robert Adams

Electronic Theses and Dissertations

Supervisory control and data acquisition (SCADA) systems are used by many critical infrastructures including electric power production and distribution, water and waste water treatment, rail transportation, and gas and oil distribution. Originally isolated proprietary systems, SCADA systems are increasingly connected to enterprise networks and the Internet and today use commercial hardware and software. As a result SCADA systems now face serious cyber-security threats. The need for testing and evaluation of developed cyber-security solutions presents a challenge since evaluation on actual systems is usually not possible and building complete physical testbeds is costly. This thesis presents the design and development of …

A Systemic Approach To Next Generation Infrastructure Data Elicitation And Planning Using Serious Gaming Methods, Ersin Ancel

Engineering Management & Systems Engineering Theses & Dissertations

Infrastructure systems are vital to the functioning of our society and economy. However, these systems are increasingly complex and are more interdependent than ever, making them difficult to manage. In order to respond to increasing demand, environmental concerns, and natural and man-made threats, infrastructure systems have to adapt and transform. Traditional engineering design approaches and planning tools have proven to be inadequate when planning and managing these complex socio-technical system transitions. The design and implementation of next generation infrastructure systems require holistic methodologies, encompassing organizational and societal aspects in addition to technical factors. In order to do so, a serious …

Bs News July/August

Building Services Engineering

No abstract provided.

Noninvasive Imaging Of The Human Rod Photoreceptor Mosaic Using A Confocal Adaptive Optics Scanning Ophthalmoscope, Alfredo Dubra, Yusufu N. Sulai, Jennifer L. Norris, Robert F. Cooper, Adam M. Dubis, David R. Williams, Joseph Carroll

Biomedical Engineering Faculty Research and Publications

The rod photoreceptors are implicated in a number of devastating retinal diseases. However, routine imaging of these cells has remained elusive, even with the advent of adaptive optics imaging. Here, we present the first in vivo images of the contiguous rod photoreceptor mosaic in nine healthy human subjects. The images were collected with three different confocal adaptive optics scanning ophthalmoscopes at two different institutions, using 680 and 775 nm superluminescent diodes for illumination. Estimates of photoreceptor density and rod:cone ratios in the 5°–15° retinal eccentricity range are consistent with histological findings, confirming our ability to resolve the rod mosaic by …

Social Innovation Concepts At Nasa: Integrating International Development Challenges And Hands-On Prototyping With Spacecraft Design Training, Leonard Yowell, Evan A. Thomas

Mechanical and Materials Engineering Faculty Publications and Presentations

The NASA Johnson Space Center Social Innovation program has been designed to encourage innovation within the NASA community that benefits both NASA's core mission as well as human needs domestically and internationally. By encouraging internal and external collaboration and providing resources including the new Johnson Space Center "Sandbox" design shop, new innovations are anticipated. Technologies developed for the human exploration of space share similar requirements with appropriate technology for the developing world. The technology goals of keeping people alive in a difficult environment involve addressing requirements for low maintenance and robustness and often include using renewable energy sources. Technologies developed …

Synthesis And Characterization Of Tethered Poly(N-Isopropylacrylamide) For Quantitative Cell Adhesion Studies, Phanindhar J. Shivapooja

Chemical and Biological Engineering ETDs

Environmentally responsive (or smart') polymers represent a new approach for controlling biofouling release. Poly(N-isopropylacrylamide) (PNIPAAm) is a thermo responsive polymer that can potentially be used to control biofouling, as it exhibits a change in its relative hydrophobicity above and below its lower critical solution temperature (LCST ~ 32\uf0b0C). This thesis reports on grafted PNIPAAm brushes, synthesized using a relatively simple and rapid method which allows atom transfer radical polymerization (ATRP) in presence of air. In this study the structure, purity and thermally responsive behavior of grafted brushes have been characterized using X-ray photoelectron spectroscopy, time-of-flight secondary ion mass spectroscopy, Fourier …

Ground Water-Surface Water Interaction Of Rio Grande Biopark Area, Albuquerque, New Mexico, Sadia Faiza

Civil Engineering ETDs

Ground water and surface water are typically considered as separate entities, but all surface water features interact with ground water in different ways. Better understanding of ground water-surface water interaction is important for effective land and water management. This study investigated the impact of surface water on ground water levels as well as soil moisture content in a small region of Albuquerque Biopark near the Rio Grande. This study involved collection of field data on soil moisture, ground water levels and observations of vegetation densities adjacent to the Biopark wetlands. Numerical models were developed of the influence of the river …

Sustainable Oxygen: A Low Power Approach For Providing Emergency Medical Oxygen For Spacecraft And Hospitals In Developing Countries, Anndee L. Huff, Evan Rhead, Zdenek Zumr, Evan A. Thomas

Mechanical and Materials Engineering Faculty Publications and Presentations

An oxygen concentrator targeting an 80% reduction in power demand over commercial systems is being developed using a pressure swing adsorption process. This system is targeted for a service interval five times longer than commercial systems, and is tolerant to high humidity environments- the leading cause of device failure in developing countries. This system could provide emergency medical oxygen in a spacecraft without increasing oxygen concentration in the vehicle. Flight surgeons seek this capability, but presently, there is no system that meets power, size, and delivery rate requirements. This type of system is also well suited for medical oxygen in …

Using Nanotechnology To Detect Nerve Agents, Mark N. Goltz, Dong-Shik Kim, Leeann Racz

Faculty Publications

Nanotechnology has opened a wide range of opportunities having potential impacts in areas as diverse as medicine and consumer products. In collaboration with researchers at the University of Toledo UT, Air Force Institute of Technology AFIT scientists are exploring the possibility of using a nanoscale organic matrix to detect organophosphate OP nerve agents. Current techniques for detecting OP compounds are expensive and time consuming. Developing a nanoscale organic matrix sensor would allow for direct, real-time sensing under field conditions. This article describes the science behind such a sensor and its possible applications. High-performance sensors are needed to protect Soldiers and …

Brain-Related Chronic Pain Disorder Diagnosis And Assessment Method, Jeffrey Hargrove

Mechanical Engineering Patents

A method for diagnosing and assessing a brain-related chronic pain disorder. The method includes assessing a subject's brain function, deterrnining the probability that a subject is suffering from chronic pain as a result of an abnormal brain function condition by obtaining a quantitative assessment of the subject's brain function, and making a statistical comparison between the subject's quantitative brain function assessment and either a database of quantitative assessments of the brain functions of normal, healthy individuals, or a database of quantitative assessments of the brain functions of individuals known to have been suffering from chronic pain as a result of …

Performance Analysis And Assessment Of A Tf-Idf Based Archetype-Snomed-Ct Binding Algorithm, Sheng Yu, Jesus Bisbal, Damon Berry

Conference Papers

Term bindings in archetypes are at a boundary between health information models and health terminology for dual model-based electronic health-care record (EHR) systems. The development of archetypes and the population of archetypes with bound terms is in its infancy. Terminological binding is currently performed “manually” by the teams who create archetypes. This process could be made more efficient, if it was supported by automatic tools. This paper presents a method for evaluating the performance of automatic code search approaches. In order to assess the quality of the automatic search, the authors extracted all the unique bound codes from 1133 archetypes …

An Investigation Of The Perception Of Gains From Undergraduate International Exchange Programs: The Tale Of Atlantis, Donal Mchale, Gul Okudan Kremer, Michael Dyrenfurth, Brian Bowe

Conference Papers

In this paper, we provide the quantitative results collected through a two-column survey instrument with which students recorded their perceptions of their educational experiences, and then summarize the qualitative study findings to outline the benefits of being immersed in different educational settings through study abroad experiences. Given the current resource constraint environment in higher education settings, we hope to help our community in making better decisions relevant to developing and sustaining study abroad programs

Teaching Sustainability Analysis In Electronics Lecture Courses, David Braun

Electrical Engineering

Based on positive prior experiences teaching sustainability analysis in electronics laboratory courses, this work explores techniques for teaching sustainability analysis in lecture courses. As difficult as it may seem to incorporate sustainability into integrated circuit courses or other engineering courses, it may prove as easy as asking students to consider how the coursework relates to sustainability issues.

The need to educate students “to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability” has gained sufficient value to deserve its own ABET Program Outcome, …

Integration Of Micropore And Nanopore Features With Optofluidic Waveguides For Single Particle Sensing, Matthew R. Holmes

Theses and Dissertations

This dissertation outlines the research and development of ground-breaking nanometer sized openings (nanopores) integrated with an on-chip optofluidic platform. This platform represents a significant advancement for single nanoparticle sensing. In this work specifically, the integrated optofluidic platform has been used to electrically and optically filter and detect single nanoparticles using ionic current blockade and fluorescence experiments. The correlation of electrical and optical signal has provided the highest sensitivity single nanoparticle measurements ever taken with integrated optofluidic platforms. The particular optofluidic platform used for this work is an antiresonant reflecting optical waveguide (ARROW). ARROW hollow and solid core waveguides are interference …

Devices And Methods For Electro-Physical Transport Of Dna Across Cell Membranes, Quentin Theodore Aten

Theses and Dissertations

A novel method for charged macromolecule delivery, called nanoinjection, has been developed at Brigham Young University. Nanoinjection combines micro-fabrication technology, mechanism design, and nano-scale electrical phenomenon to transport exogenous DNA across cell membranes on a nano-featured lance. DNA is electrically accumulated on the lance, precision movements of microelectromechanical systems (MEMS) physically insert the lance into cell, and DNA is electrically released from the lance into the cell. Penetration into the cell is achieved through a two-phase, self-reconfiguring metamorphic mechanism. The surface-micromachined, metamorphic nanoinjector mechanism elevates the lance above the fabrication substrate, then translates in-plane at a constant height as the …

Ceas E-News 06.27.2011, College Of Engineering And Applied Sciences

College of Engineering and Applied Sciences News

Outstanding Student Engineer, BTR Bike Race

Design Projects With Out-Of-Town Companies, Lizabeth Schlemer

Industrial and Manufacturing Engineering

The capstone design class in the industrial engineering department at California Polytechnic State University, San Luis Obispo (Cal Poly) includes projects with companies. The projects are large ambiguous facilities design problems that allow students to incorporate many aspects of the IE curriculum. For the past 15 years students have been participating in these projects with local companies. Over the past several years, companies from out of town (200 miles to the north in Mountain View or 200 miles to the south in Oxnard) have participated. These out of town companies have presented certain logistical issues, but they have proven to …

A New Model Of Project Based Learning, Ron Ulseth, Jefferey E. Froyd, Thomas A. Lotzinger, Dan Ewert, Bart Johnson

Integrated Engineering Department Publications

A new model for engineering education has been developed and funded. The model is 100% project based learning (PBL) where the students develop their own learning objectives. The projects are authentic needs contributed by collaborating industries. Students monitor the acquisition of 32 technical competencies and all of the design and professionalism competencies required of new practicing engineers. The reasons for the new model, description of the model, research supporting the model, methods for evaluating the model and its transportability are discussed.

The 4+1 Program And Distance Learning Meeting Objectives And Outcomes, Daniel W. Walsh, Lanny Griffin, Robert S. Crockett

Biomedical Engineering

Graduate engineering education is a key to the maintenance of U.S. competitiveness in the world market. The world has been an extremely dynamic engine during the last fifty years, and we have witnessed a dramatic change in the world order. The change has been evolutionary in many cases, but events in Eastern Europe, the Middle East and the erstwhile Soviet Union are only slightly less cataclysmic than the Second World War. In a world where strength is measured in terms of the financial resource, the technological ability and the intellectual capability of a populace Japan, China, India and the EEC …

Developing A Regional Land Use Drought Index In Florida, Chi-Han Cheng, Fidelia Nnadi

2011 Symposium on Data-Driven Approaches to Droughts

Drought is a natural phenomenon that occurs when a significant decrease of water availability during a significant period of time and over a larger area. Drought indices can be a useful tool to assess and respond to drought. However, current drought indices could not fully show the land use effects and they have limitation in data sources. ENSO influence the climate of Florida; where El Niño years tend to be cooler and wetter, and La Niña years tend to be warmer and drier than normal in the fall through the spring, with the strongest effect in the winter. Both prolonged …

A Look At 20th Century Droughts, Vijay P. Singh, Ashok K. Mishra

2011 Symposium on Data-Driven Approaches to Droughts

Droughts exercise a profound effect on the social and economic fabric of nations. Many nations of the world experienced droughts encompassing the full spectrum of severity, areal extent and duration. The result has been that the economic development was hampered and many countries have not yet recouped fully from the ravages of droughts. The first decade of the 21st century has also witnessed varying degrees of droughts across the globe. Therefore, we ask the following questions: (a) Do droughts affect every part of the world? (b) Are there similarities in major droughts around the world? (c) Are climate change and …

Reconfigurable Sampling For Enhanced Energy Efficiency In Power-Constrained Wireless Systems, Timothy Kurp

Master's Theses

Advancement in microelectronics and wireless communications has nurtured the development of low power and low cost wireless systems such as sensor networks. Each node is typically driven by a battery, which has a limited energy capacity that directly constrains node, and network lifetime. This presents a bottleneck for the widespread exploitation of wireless sensing technology. Therefore, improving the energy efficiency of wireless sensing devices is of critical importance and has attracted the attention of the research community.

In this work, a data-driven method has been proposed and systematically investigated. Specifically, this technique reconfigures, in real time, the rate of data …