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Advancements In Visualization, Post-Processing And Ai-Enhanced Modeling Of Multi-Scale Micromechanics For Composite Materials, Joao Guilherme Brites Rei
Advancements In Visualization, Post-Processing And Ai-Enhanced Modeling Of Multi-Scale Micromechanics For Composite Materials, Joao Guilherme Brites Rei
Masters Theses
This study addresses some of the primary deficits of a localization/homogenization workflow for composite materials by focusing on the visualization and enhancement of models based on GMC and HFGMC, with emphasis on their implementation within the NASMAT ecosystem.
This thesis details the development of two dynamic, ParaView-based plugins that convert large hierarchical simulation outputs into interactive insights. While NASMATDiscreteElement systematizes RUC creation with transparent parametrization in a reproducible GUI, NASMATExplorerRUC enables the inspection of deeply nested datasets through accurate cell picking and synchronizes comparisons between parent and child views. Additionally, a shallow U-Net neural network is optimized on HFGMC data …
Evaluating Utilidor Performance And Ground Temperature Variability In UtqiaġVik, Tate Rachow
Evaluating Utilidor Performance And Ground Temperature Variability In UtqiaġVik, Tate Rachow
Geosciences
Permafrost degradation in Arctic regions poses increasing risks to infrastructure as climate warming accelerates thaw processes, alters hydrology, and deepens the active layer. In Utqiaġvik, Alaska, utilidors— utility conduits—play a vital role in protecting water and wastewater services, yet their thermal performance under changing conditions remains poorly constrained. This thesis evaluates the thermal behavior of the Site U-1 direct buried pipes on Stevenson Street using historical thermistor resistance data converted to temperature, combined with calibrated two- dimensional TEMP/W numerical models. The models incorporate layered backfill materials and polyurethane insulation, while also simulating operational influences of water and wastewater temperatures. Calibration …
The Importance Of Leader-Member Exchange And Psychological Contracts In Highly Qualified Researchers, Robin L. Ingerick Dba
The Importance Of Leader-Member Exchange And Psychological Contracts In Highly Qualified Researchers, Robin L. Ingerick Dba
Theses & Dissertations
This study examined the significance of the relationship between leader-member exchange (LMX) and psychological contracts in United States-based research organizations. When the organization-manager-employee relationship deteriorates, psychological contract breaches can occur, negatively affecting employee outcomes and the organization's financial success and stability. Existing knowledge highlights several factors that influence relationships, including reciprocated treatment, work behaviors and reactions, trust, professional respect, affect, mutual interaction, work autonomy, communication, job satisfaction, and fulfillment. The study sought to determine to what extent is there a predictive relationship between LMX and psychological contracts (employee obligations, employer obligations, fulfillment, and contract transitions) of highly qualified United States-based …
Engineering Risk And Indigenous Resilience Toward Intelligent Decision Support For Mining In Ancestral Lands, Izech Brian O. Edwin, King Harold A. Recto
Engineering Risk And Indigenous Resilience Toward Intelligent Decision Support For Mining In Ancestral Lands, Izech Brian O. Edwin, King Harold A. Recto
Electronics, Computer, and Communications Engineering Faculty Publications
Mining within ancestral territories reveals an ongoing conflict between technical viability and Indigenous consent. This collaborative study, conducted by an engineering scholar and a policy researcher of Indigenous heritage in Benguet among the Ibaloi and Kankanaey peoples, investigates how risk transparency and policy alignment can bridge existing divides, while formulating principles applicable to other Indigenous mining contexts. The study provides an initial evaluation of the feasibility of a proposed large-scale mining operation within a risk-informed, data-driven governance framework. Three elements of engineering risk were assessed utilizing literature-derived and proxy parameters: (1) Land degradation is indicated by a Soil Productivity Index …
Multi-Cater Pack Heat Sealer, Ivan Medina-Zepeda, Laurent Hirakata, Donovan Furtado, Cody Ngan
Multi-Cater Pack Heat Sealer, Ivan Medina-Zepeda, Laurent Hirakata, Donovan Furtado, Cody Ngan
Mechanical Engineering
The Multi-Cater Pack Heat Sealer was developed to support Achievement House, a non-profit organization that employs adults with intellectual and physical disabilities and is facing increasing demand for sealed cater packs. Existing single-pack sealers limited both throughput and accessibility, which led to the creation of a 3D printed attachment for a 40-inch impulse heat sealer. The attachment allows nine packs to be sealed at the same time and includes a tray-style trapdoor that allows for quick unloading. The need for accessibility and usability guided the design throughout the process. Alignment guides improve placement consistency, and the ergonomic layout accommodates both …
Teachers Of Students With Visual Impairments (Tsvis) Assistive Technology (At) Competencies: An Update Study, Benjamin Kendall Lytle
Teachers Of Students With Visual Impairments (Tsvis) Assistive Technology (At) Competencies: An Update Study, Benjamin Kendall Lytle
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
Assistive technology (AT) is essential for supporting access, independence, and learning among students with visual impairments. Teachers of students with visual impairments (TSVIs) are expected to integrate AT into instruction and ensure their students are prepared for academic, social, and workforce demands. The original list of 111 AT competencies for preservice TSVIs, developed by Smith et al. (2009), provided an important foundation but has not been revised despite significant technological advances over the past decade. Outdated competencies risk limiting teacher preparation programs and leaving educators underprepared to address the realities of today’s classrooms. A revised and streamlined competency framework is …
Enhancing Grid Integration Of High-Power Loads Through Modular Unfolding-Based Power Conversion With Decentralized Control, Sanat R. Poddar
Enhancing Grid Integration Of High-Power Loads Through Modular Unfolding-Based Power Conversion With Decentralized Control, Sanat R. Poddar
All Graduate Theses and Dissertations, Fall 2023 to Present
The transition to electric vehicles (EVs) is a critical step toward reducing greenhouse gas emissions and creating a cleaner, more sustainable transportation sector. However, many drivers — particularly those operating larger vehicles such as trucks and buses — face significant challenges, including limited driving range and lengthy charging times. High-power, fast-charging stations, which can rapidly replenish EV batteries, are therefore essential for mitigating these barriers and making electric transportation practical across all vehicle classes.
Despite the promise of electric vehicles, deploying high-power fast-charging stations presents significant challenges. They require large amounts of electricity, making them expensive to install, operate, and …
A Low-Power Mixed-Signal Potentiostat System-On-Chip With Integrated Dual-Slope Adc, Seth Mcrobert
A Low-Power Mixed-Signal Potentiostat System-On-Chip With Integrated Dual-Slope Adc, Seth Mcrobert
Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research
This thesis presents the design and characterization of a low-power mixed-signal potentiostat that was integrated with a 65 nm core in a SoC for low-power electrochemical sensing applications. The system integrates a low-noise transimpedance-based potentiostat front end with a 12-bit dual-slope analog-to-digital converter (ADC) for accurate current-to-digital conversion. The potentiostat core—comprising the control amplifier, current-mirror network, and transimpedance amplifier—consumes 38.2 µA from a 2.5 V supply (95.5 µW) and achieves an input-referred noise floor of 113 µVRMS over a 330 Hz bandwidth, while having an input current range from 1 nA to 20 µA and a noise-limited sensitivity of 56.4 …
Evaluating The Preparedness Of Local Zoning Regulations For Flood Risk Reduction In The Most Affected Local Jurisdictions In Nebraska, Md Asaduzzaman Noor
Evaluating The Preparedness Of Local Zoning Regulations For Flood Risk Reduction In The Most Affected Local Jurisdictions In Nebraska, Md Asaduzzaman Noor
Community and Regional Planning Program: Theses
Flooding has profound social, economic, and environmental impacts on local communities, and zoning plays a critical role in mitigating these risks. The 2019 Nebraska floods, among the most severe in the state’s history, highlighted the urgent need to strengthen local preparedness and mitigation strategies. This study assesses the extent to which local zoning regulations in Nebraska’s most affected jurisdiction, including rural areas, address flood risk reduction. A systematic review of 117 zoning ordinances from counties, cities, towns, and villages, we applied a structured analytical framework encompassing regulatory and permitting policies, voluntary and incentive-based measures, and nature-based solutions. The results show …
Evaluating Psychosocial Stressors And Mental Well-Being Of Construction Professionals From The Management Standpoint: An Exploratory Study, Md Tauhidul Karim
Evaluating Psychosocial Stressors And Mental Well-Being Of Construction Professionals From The Management Standpoint: An Exploratory Study, Md Tauhidul Karim
Masters Theses
Construction professionals face persistent workplace stressors that undermine their mental well-being outcomes. Despite progress in general job-related stressors, social and interpersonal aspects of psychosocial stressors traditionally remain underexplored in the construction management research. The present study examines how social and interpersonal factors influence construction workers’ mental well-being and how management’s awareness, responsiveness, and strategic roles evolved in the transition of the COVID-19 pandemic at the organizational level. An integrative mixed-methods approach was employed, combining a systematic literature review, a bibliometric analysis, and an exploratory case study to capture the current landscape of mental well-being and management standpoints in the US …
Flood-Level Estimation Using Aerial Imagery, Yisen Zhang
Flood-Level Estimation Using Aerial Imagery, Yisen Zhang
Electrical & Computer Engineering Projects for D. Eng. Degree
Reliable flood-level estimation using aerial UAV (Unmanned aerial vehicle) imagery is essential for effective post-disaster assessment and rapid emergency response. This study utilizes a UAV-based dataset, referred to as the UVA dataset, which integrates multiple public datasets and manually labeled UAV images, together with a multi-stage vehicle-centric framework for flood-depth estimation. The UVA dataset integrates images from multiple public sources, including Unmanned Drone Water Assessment (UDWA), Unmanned Aerial Vehicle Detection and Tracking (UAVDT), Car Parking Lot (CARPK), and additional UAV-view images collected from the internet, followed by manual annotation for water depth, viewing angle, and altitude labels. In the proposed …
Air Force Institute Of Technology Research Report 2023, Air Force Institute Of Technology
Air Force Institute Of Technology Research Report 2023, Air Force Institute Of Technology
AFIT Documents
This report summarizes the research activities of the Air Force Institute of Technology's Graduate School of Engineering and the Graduate School of Logistics and Acquisition Management. It describes research interests and faculty expertise; list student theses/dissertations; identifies research sponsors and contributions; and outlines the procedure for contacting either school.
Polypropylene/Polyethylene Blends With Asymmetric Viscosity: Fabrication, Characterization, And Recycling Potential, Bernadine Daichendt
Polypropylene/Polyethylene Blends With Asymmetric Viscosity: Fabrication, Characterization, And Recycling Potential, Bernadine Daichendt
All Dissertations
Polyolefin materials, polypropylene (PP) and polyethylene (PE), are widely used in day-to-day life both commercially and industrially, offering versatile applications due to their mechanical and chemical properties. The high consumption rate of these materials makes them important targets for recycling efforts. However, there are multiple contributing factors leading to low recycling of PP and PE, chiefly sorting factors: chemical similarity, changed properties after multiple rounds of processing, and the use of processing aids. It is necessary to point out that, because of multiple melt processing cycles, recycled PP has decreased molecular weight due to chain scission. Conversely, recycled PE molecular …
Degradation Of Cobalt Chrome Molybdenum Hip And Knee Implants In Vivo And In Vitro, Peter William Kurtz
Degradation Of Cobalt Chrome Molybdenum Hip And Knee Implants In Vivo And In Vitro, Peter William Kurtz
All Dissertations
Cobalt Chrome Molybdenum (CoCrMo) remains a popular material choice for femoral condyles in total knee arthroplasty and for acetabular liners in dual mobility total hip designs. CoCrMo has been phased out of conventional THA designs due to its correlation with adverse effects such as ALTR and ALVAL. It is less understood if the mechanisms (i.e. abrasive wear to the surface of the implant) that release metal ions into the surrounding tissue occur at similar rates as seen in conventional THA. Additionally, it is unknown what effect the secondary damage modes such as electrocautery damage and adhesive wear have on these …
Power Distribution Controller For Formula Sae Vehicles, Michael Yuen
Power Distribution Controller For Formula Sae Vehicles, Michael Yuen
Electrical Engineering
The Power Distribution Controller (PDC) is designed for low-voltage (12V) automotive applications, specifically Formula SAE vehicles. It aims to replace the current and outdated MOSFET-based system, which suffers from inefficiencies such as lossy current sense resistors and limited configurability. Instead, this new system uses a PROFET-based architecture controlled over the Controller Area Network (CAN) and an updated microcontroller, enabling intelligent power management and data logging.
Designed with FSAE regulations in mind, the PDC not only enhances the reliability of low-voltage systems but also provides a quickly adaptable solution to fuse boxes. It achieves this by providing firmware-adjustable overcurrent protection, incorporating …
A Study On Utilizing Coherently Coupled Orbital Angular Momentum Beams For Maritime Sensing And Communication, Evan Robertson
A Study On Utilizing Coherently Coupled Orbital Angular Momentum Beams For Maritime Sensing And Communication, Evan Robertson
All Dissertations
A large portion of the world is covered in water which introduces a couple of key challenges in communication and sensing systems. The impact of particulates in the water will limit the ability to successfully transmit information through the water. The study of how the channel impacts specific frequencies and the ability to transmit more information at a single time can limit the impact of this environment in how it degrades an optical communication system. In sensing applications, it is important to detect information related to an object’s motion which will either be towards or away from a system, or …
Micro/Nanomechanical Properties Of Top-Seeded Melt Grown Ybco Single Crystals Determined Using Depth Sensing Indentation, Ugur Kolemen, Cafer Mert Yesilkanat, Fikret Yilmaz, Fatih Dogan, Orhan Uzun
Micro/Nanomechanical Properties Of Top-Seeded Melt Grown Ybco Single Crystals Determined Using Depth Sensing Indentation, Ugur Kolemen, Cafer Mert Yesilkanat, Fikret Yilmaz, Fatih Dogan, Orhan Uzun
Materials Science and Engineering Faculty Research & Creative Works
Mechanical properties of the bulk YBa2Cu3O7-x (YBCO) single crystal superconductor, prepared by using the Top Seeded Melt Growth (TSMG) method, were determined. Property measurements were conducted by the nanoindentation method under various loads and the micro indentation method at different temperatures. Hardness (H) and reduced elastic modulus (Er) values were calculated by using the Oliver–Pharr method. According to hf/h max values found from load- displacement curves, there is a sink in behavior around outer rim of the indents that was confirmed by atomic force microscopy (AFM) analysis. Nanoindentation analyses conducted on upper section, middle section and subsection revealed that all …
Deterministic Methods To Improve The Field-Of-View For Direction Finding Using Sparse Digital Arrays, Nolan J. Egging
Deterministic Methods To Improve The Field-Of-View For Direction Finding Using Sparse Digital Arrays, Nolan J. Egging
Master's Theses
Direction finding algorithms are used with digital phased arrays to determine the incoming angle of arrival (AoA) of an incident signal. These algorithms, and direction finding as a whole, have a wide range of civilian and military applications from radar, electronic reconnaissance, mobile communication, et cetera. However, for situations where the spacing between antenna elements needs to be large, gating lobes appear in the radiation pattern of analog arrays. This work demonstrates that for digital beamforming algorithms, the field of view (FoV) of a uniform linear digital array matches the grating lobe free range of a similarly spaced analog array. …
G2pdeep-V2: A Web-Based Deep-Learning Framework For Phenotype Prediction And Biomarker Discovery For All Organisms Using Multi-Omics Data, Shuai Zeng, Trinath Adusumilli, Sania Zafar Awan, Manish Sridhar Immadi, Dong Xu, Trupti Joshi
G2pdeep-V2: A Web-Based Deep-Learning Framework For Phenotype Prediction And Biomarker Discovery For All Organisms Using Multi-Omics Data, Shuai Zeng, Trinath Adusumilli, Sania Zafar Awan, Manish Sridhar Immadi, Dong Xu, Trupti Joshi
Biomedical Sciences
Multi-omics data offers rich insights into complex traits across organisms, yet integrating and analyzing these datasets for phenotype prediction and marker discovery remains challenging. Researchers need accessible tools that combine deep learning, hyperparameter optimization, visualization, and downstream analysis in a unified web platform. To address this, we developed G2PDeep-v2, a web-based platform powered by deep learning for phenotype prediction and marker discovery from multi-omics data across a wide range of organisms, including humans and plants. The server provides multiple services for researchers to create deep-learning models through an interactive interface and train these models using an automated hyperparameter tuning algorithm …
Llm-Powered Question Answering For Object States In Virtual Reality, Shiyi Ding
Llm-Powered Question Answering For Object States In Virtual Reality, Shiyi Ding
Master's Theses
Recent advances in large language models (LLMs) and multimodal large language models (MLLMs) enable natural language–based querying in virtual reality (VR). However, VR environments are highly localized, personalized, and dynamic, making it challenging for general-purpose models to answer environment-specific queries or reason about subtle object state changes. To address these challenges, this thesis develops two systems for 3D question answering in VR.
First, we present RAG-VR, the first retrieval-augmented 3D question-answering system designed for VR. RAG-VR augments an LLM with external knowledge retrieved from a localized knowledge database and includes a pipeline for extracting environmental and user-related information. To improve …
Feed Network Design For Passive Beamforming In Hemispherical Phased Arrays, Daniel Flores
Feed Network Design For Passive Beamforming In Hemispherical Phased Arrays, Daniel Flores
Theses and Dissertations
This thesis presents the design, fabrication, and evaluation of a four-element microstrip patch antenna array with a passive 1 to 4 corporate feed network operating at 5 GHz. A single inset-fed patch was developed on Rogers DiClad 880 to ensure accurate tuning and mechanical flexibility, achieving a measured resonance of 5.009 GHz with excellent return loss. The corporate feed network, synthesized using T-junction dividers and quarter-wave transformers, demonstrated strong impedance matching, balanced amplitude distribution, and broadside realized gain near 10 dBi when integrated with the array.
Beam steering was examined through simulation-based phase control, revealing effective scanning up to approximately …
Rapid Prototyping Of Low-Cost Sensor Systems Towards A Platform For Upper Limb Posture Estimation, Russell Rathbun
Rapid Prototyping Of Low-Cost Sensor Systems Towards A Platform For Upper Limb Posture Estimation, Russell Rathbun
Electrical Engineering and Computer Science Undergraduate Honors Theses
Physical therapy requires patients to perform repeated actions to achieve meaningful results in rehabilitation. This thesis explores production methods and various sensor systems by utilizing rapid prototyping, inertial measurement units (IMUs), and capacitive sensor arrays (CSAs). CSAs can be made from a wide ar- ray of materials and techniques including 3d printing and laser ablation–to rapidly create CSAs that can be custom fit to enable proximity, force, and touch detection. IMU and CSA systems individually are able to track upper limb movements, ges- tures, and positions. This combination of sensors enables accurate upper limb pos- ture estimation of patients. This …
Mozgus, Damian Cerda, Madison Lopez
Mozgus, Damian Cerda, Madison Lopez
Computer Science and Software Engineering
The indie game market is flooded with genre experiments, yet few successfully combine fast-paced action with meaningful strategic decision-making. Our project aims to fill this gap by creating a game that fuses top-down action combat with resource-management tycoon mechanics. We found that in many games, the management phases lack mechanical stakes. Our goal was to intertwine these systems so that choices made in one phase meaningfully impact the other.
Reinforcement Learning Based Security Schemes For Distributed Ai Systems, Ashan Chamath Gunawardena
Reinforcement Learning Based Security Schemes For Distributed Ai Systems, Ashan Chamath Gunawardena
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
Distributed machine learning (DML) is a component of modern intelligent systems, enabling collaborative training across devices such as mobile clients, vehicles, and edge networks. However, the decentralized nature of these systems introduces vulnerabilities, particularly data poisoning attacks that compromise model integrity and degrade performance. Traditional defenses, such as statistical filtering, robust aggregation, and privacy-preserving techniques, often struggle to adapt to overwhelming adversaries or operate under strict privacy and real-time constraints. This dissertation proposes the use of reinforcement learning (RL) and deep reinforcement learning (DRL) based misbehavior detection schemes that dynamically identify poisoning attempts in distributed AI systems, including federated learning, …
Ethical Decision-Making Processes In Authentic Environmental Engineering Contexts Through Systems Thinking And Team Collaboration Lenses: An Embedded Single Case Study, Toluwalase Eniola Brower
Ethical Decision-Making Processes In Authentic Environmental Engineering Contexts Through Systems Thinking And Team Collaboration Lenses: An Embedded Single Case Study, Toluwalase Eniola Brower
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
Ethical and professional responsibility is a critical learning outcome emphasized in ABET accreditation. However, ethics instruction in engineering education often lacks integration of system-level considerations such as economic, environmental, and societal contexts, that are essential for developing engineering solutions that ensure the safety and welfare of diverse stakeholders. This embedded single-case study investigated the integration of authentic ethics instruction within a junior-level environmental engineering course at a Midwestern U.S. university during spring 2025 and explores how civil engineering student teams within the course engage in ethical decision-making process during authentic problem-solving.
The instructional intervention consisted of four problem-based ethics modules, …
Lace Network Firmware: A Polarfire Fpga Network For Data Routing And Command Interfacing In Space Applications, Kade C. Howes
Lace Network Firmware: A Polarfire Fpga Network For Data Routing And Command Interfacing In Space Applications, Kade C. Howes
All Graduate Theses and Dissertations, Fall 2023 to Present
Modern small spacecraft rely on powerful yet efficient onboard compute devices to process data from sensors in real-time due to tight power and volume constraints. This work explores a new compute device system built from PolarFire Field-Programmable Gate Arrays (FPGAs), which are power-efficient, reprogrammable chips well-suited for space applications. The system connects via a central controller FPGA with one or multiple companion processing FPGAs, allowing sensor data to be quickly received and shared across the network. Standardized data formats and interfaces increase compatibility with spacecraft computers. By simplifying data handling and using high-speed communication links, this architecture makes it easier …
Integrating Neural Control And Finite Element Muscle Modeling: A Predictive Neuromusculoskeletal Framework For Investigating Neurodegenerative Disease, Colton Babcock
Boise State University Theses and Dissertations
Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) disrupt the interplay between neural control and musculoskeletal function, leading to progressive motor decline and loss of force control and production. Traditional experimental and clinical approaches are limited in their ability to capture the multiscale, nonlinear mechanisms driving these impairments. This dissertation presents a novel predictive neuromusculoskeletal (NMS) modeling framework that integrates physiologically accurate motor neuron dynamics with three-dimensional finite element (FE) muscle models. Using subject-specific muscle geometry and fiber architecture of the tibialis anterior, the model simulates realistic force generation under both healthy and ALS-affected conditions. The neural component incorporates a …
A Machine Learning Approach To Estimating Agricultural Return Flows: A Case Study Of The Twin Falls Canal Company In Idaho, Kendra Alise Figgins
A Machine Learning Approach To Estimating Agricultural Return Flows: A Case Study Of The Twin Falls Canal Company In Idaho, Kendra Alise Figgins
Boise State University Theses and Dissertations
Idaho is the third largest water user in the United States due to its extensive agriculture industry (Murray, 2018). Irrigation has allowed farmers to take advantage of the warm climate and rich soils of the Eastern Snake River Plain to develop one of the nation’s most productive agricultural regions. This area now contains one-third of Idaho’s irrigated acres (Idaho Department of Water Resources, 2024). It also contains critical hydrologic connections between the Snake River and the Eastern Snake Plain Aquifer.
Farming practices in Idaho have gradually shifted over time. Warming temperatures and increased irrigation efficiency are allowing an expansion of …
Sustainability Assessment Of Ground Improvement Techniques: A Life Cycle Analysis Of Lime, Cement, Geopolymers And Biopolymers For Roadway Application, Jillian R. Frost
Sustainability Assessment Of Ground Improvement Techniques: A Life Cycle Analysis Of Lime, Cement, Geopolymers And Biopolymers For Roadway Application, Jillian R. Frost
Boise State University Theses and Dissertations
Ground improvement design (GID) is a vital part of constructing safe, long-lasting infrastructure. Traditionally, this is done with a chemical additive such as lime or cement that is mixed with in-situ soil to improve soil parameters such as compressibility, and strength. These stabilizers produce high amounts of carbon emissions. As a response, engineers and researchers are beginning to develop new stabilization methods using biopolymers and geopolymers in hopes of achieving comparable soil stability results as well as reduced environmental impacts.
This thesis work integrates a life-cycle analysis (LCA) and life-cycle-cost-analysis (LCCA) framework to evaluate and compare four soil stabilizer types: …
Harnessing Bioscaffold-Coupled Stimulation Through Electroactive Graphene Foam For Enhanced Cellular And Mechanical Responses: Applications In Cartilage Tissue Engineering, Mone't Sawyer
Boise State University Theses and Dissertations
Osteoarthritis is a leading cause of joint degeneration, with limited treatment options that fail to restore native cartilage. Tissue engineering offers a promising strategy by combining cells, scaffolds, and bioactive cues to regenerate functional tissue, though challenges remain in developing systems that integrate and precisely control these signals in three-dimensional environments. This work establishes a scaffold-coupled electrical stimulation (ES) platform using electroactive graphene foam (GF) to modulate cellular and mechanical responses relevant to cartilage tissue engineering. Custom stereolithography-printed bioreactors were developed to deliver low-voltage biphasic square waves (20–60 mVpp, 1 kHz) directly to GF scaffolds under submerged culture, maintaining waveform …