Digital Commons Network^™

A Critical Perspective On The Society Of Environmental Toxicology And Chemistry's Adherence To Founding Principles— Opportunities For The Future, Barnett A. Rattner, Annegaaike Leopold, Carys L. Mitchelmore, Glenn W. Suter, Mark S. Johnson, Adriana C. Bejarano, Lawrence A. Kapustka, Niranjana Krishnan, Derek C. G. Muir, Beatrice O. Opeolu, Martha Georgina Orozco-Medina, April Reed, Bruce W. Vigon, Adam R. Wronski

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

The Society of Environmental Toxicology and Chemistry (SETAC) is a global organization whose mission is the advancement of environmental science and management through collaboration, leadership, communication and education. On SETAC's 45th anniversary, the following question was raised: Are the 1979 founding principles of SETAC, multidisciplinary approaches to solving environmental problems, multisector engagement and scientific objectivity, still useful, adequate and effective in fulfilling its mission? In a special session held at the 45th Annual Meeting in Fort Worth, Texas, United States, a critical evaluation of the founding principles was initiated by reviewing SETAC's history and ongoing activities, and recommendations were made …

Investigation Of Succinylated Zwitterionic Polyethylenimine/Dna Complexes: Performance In Serum, Internalization, And Intracellular Fate, Levi Lampe

Theses and Dissertations--Chemical and Materials Engineering

Gene therapy has promised to revolutionize medicine since the earliest clinical trials, but a lack of delivery methods that are both safe and efficient has hampered progress. Gene therapy with viral vectors is effective at delivering nucleic acids to cells, but is associated with dangerous immunogenic responses and cancer-causing insertions into the genome. Viral vectors are also among the most prohibitively costly therapeutics in medicine. Polymeric vectors avoid these dangers and are made from inexpensive, off-the- shelf materials, but have been hindered by poor efficiency compared to viral vectors.

A benchmark polymer for in vitro nucleic acid delivery has been …

Anaerobic Digestion Of Food Waste Components: Modeling Biogas Production, Opeyemi E. Adelegan

Civil Engineering Dissertations

Food waste constitutes the single largest component of municipal solid waste landfilled in the United States — approximately 22% of 292.4 million tons generated in 2018 — and its anaerobic decomposition releases methane, a greenhouse gas with global warming potential approximately 27–30 times that of carbon dioxide over a 100-year horizon (IPCC, 2021). Anaerobic digestion (AD) offers an alternative management pathway that recovers energy and produces nutrient-rich digestate, but AD performance varies by as much as five-fold across food waste streams (130–630 m³ CH₄ per Mg VS added), and existing predictive tools either treat food waste as a …

Beyond The Square Pulse: Waveform Shape, Eeg Correlates, And The Pursuit Of Natural Sensation In Tens, Jason Whitson

Honors Undergraduate Theses

This study investigates the relationship between electrical stimulus characteristics of shape and charge on evoked sensations and electroencephalogram (EEG) data during multi-waveform transcutaneous electrical nerve stimulation (TENS) of the median nerve. Neuromodulation methods have traditionally had little control over the location and quality of their associated evoked sensation (e.g., electric, vibration, touch). This experiment utilized five unique stimulus waveforms during TENS stimulation. EEG data were collected concurrently to provide an introductory objective measure of the neural responses underlying these sensory changes. Eleven participants completed three tasks (thresholding, super-threshold stimulation, two-alternative forced choice) using a two-electrode TENS approach. Stimulus waveforms were …

Contours Of Duration: Movement Authored Through Form—A Behavior Archive, Jood Senussi Elbeshti

Theses and Dissertations

Insect anatomy offers an elegant example of motion derived from structure. Inspired by insect movement, Contours of Duration employs a cam-and-follower system consisting of moving, leg-like parts, designed to engage a series of rotating cams, such that the shape of each cam’s surface activates the legs in unique ways, generating repetitive movement, and demonstrating how geometry produces distinct motion behaviors over time. Through iterative experimentation and controlled variation, trace emerges as a central methodology, whereby movement, over time, creates a distinct pattern of marks, making motion legible and reflecting how subtle changes to surface and form generate different behavioral outcomes. …

De Novo Protein Binding To Zinc Oxide Through Biomineralization Pathways, Jean-Mark A. Francis

Theses and Dissertations

De novo proteins are structurally distinct from proteins found in nature and thus capable of having their amino acid sequence modified to accomplish tasks such as increasing protein-nanoparticle binding without unfolding or decomposing. Zinc Oxide nanoparticles are functionally distinct from their bulk counterparts and are widely used as semiconductors in a variety of fields such as medicine and agriculture. With demand for these nanoparticles increasing, environmentally sustainable methods of Zinc Oxide nanoparticle synthesis are being investigated as an eco-friendly alternative to currently utilized but environmentally hazardous chemical and physical techniques. This research investigates the binding characteristics between Zinc Oxide nanoparticles …

Feasibility Of Corn Stover For Biogas Production In Northwestern Illinois: A Case Study Of Jo Daviess And Carroll Counties, Anthony Amotoe-Bondzie

Masters Theses

The growing demand for renewable energy and sustainable waste management has intensified interest in agricultural residues such as bioenergy feedstocks. This study evaluated the feasibility of converting corn stover into biogas through anaerobic digestion (AD) in Jo Daviess and Carroll Counties, Illinois, with consideration of the Savanna Industrial Park as a potential centralized processing hub. Although corn stover represents one of the largest biomass resources in the United States, this research identifies a critical gap between theoretical availability and practically recoverable feedstock. Using a mixed-methods framework, the study integrates biomass quantification, methane yield modeling, economic analysis, and policy assessment. Results …

Design And Validation Of A Novel Patterned Microfluidic Culture Platform For Hipsc-Cm Maturation, Anisia Gabriela Țiplea

Dartmouth College Master’s Theses

Adult cardiomyocytes (CMs) are among the most challenging cells to culture in vitro, given their poor adherence to plastic culture wells and poor maturation outside the native extracellular matrix (Narkar et al., 2022). Human induced pluripotent stem cell-derived CMs (hiPSC-CMs) offer a viable alternative to study heart development and disease progression. While not comparable to adult CMs in their maturity (Narkar et al., 2022), they mimic the clinical phenotypes of heart failure and are more feasible to culture. Nevertheless, hiPSC-CMs require specialized culture conditions that cannot be achieved with 2D static culturing, which fail to replicate native tissue environments (X. …

Seasonal Wastewater Monitoring And Quantitative Microbial Risk Assessment Of Escherichia Coli In A University Wastewater System, Pathum Thani, Central Thailand, Natsima Tokhun, Natagarn Tongphanpharn, Weerawat Ounsaneha, Montip Jankeaw, Wiriyabhorn Klomsungcharoen, Patsara Wongsudi, Yawanart Ngamnon, Cheerawit Rattanapan, Kwang Mo Yang

Applied Environmental Research

In this study, the physicochemical properties of wastewater were characterized, and a quantitative microbial risk assessment (QMRA) of E. coli was conducted in the wastewater treatment system of the Faculty of Science and Technology, Valaya Alongkorn Rajabhat University, under the Royal Patronage, Pathum Thani, Thailand (VRU-SciTech). This study was conducted because the current water-quality assessment does not include the QMRA or evaluate the occupa-tional and incidental public risk of infection. Over a one-year monitoring period, this study quantified wastewater generation (~6.09 L person-1 day-1; ~3.21 × 103 m3 year-1) and analyzed its physicochemical parameters and E. coli concentrations. High concentrations …

Evaluation Of Soil Moisture Content, Ph, And Dominant Microorganisms In Crude Oil–Contaminated Soil Treated With Cow Dung, Indole-3-Acetic Acid (Iaa), And Simulated Microgravity, Amenze Ovenseri, Tawari-Fufeyin P.

Applied Environmental Research

Crude oil negatively affects soil physicochemical properties and microbial activity, thereby hindering plant growth and posing notable environmental and agricultural issues. The combined effects of cow dung, indole-3-acetic acid (IAA), and simulated microgravity on the recovery of soil degraded by crude oil were explored using Zea mays as the test plant. Soil was contaminated with crude oil at different concentrations (0%, 1%, 3%, and 5% v/w), with each concentration comprising eight treatments: cow dung, Zea mays seeds exposed to microgravity, and IAA alone or in combination. Changes in plant height, soil pH, soil moisture content, and soil microbial diversity were …

Integrated Optical Probes For Confocal Scanning Imaging And Adjustable Coherent-Gated Dynamic Sensing, Yonglin Huang

Graduate Studies Theses and Dissertations 2026

Optics and photonics have been one of the most important sciences and technologies that impact modern human life in a big way. For example, fiber-optics for communications and artificial intelligence. Optical probes are critical components for optical imaging and optical sensing technologies that have been actively researched and developed in the past decades. Advanced fiber-optic sensor probes with smaller size, better performance, lower noise, higher photon efficiency, rapid sensing time, and lower cost are needed in many applications, such as nanoscale material science, chemistry, and biomedical fields, etc.  In this project, new fiber-optic sensor probe technologies and integrated micro-optic devices …

Seasonal Variations In Co2 Emission From Poultry Manure-Amended Soils In Two Contrasting Tropical Agroecosystems, Gladys M. Akande, Adebayo J. Adeyemo, Chidozie J. Oraegbunam, Iduh J.J. Otene, Ezekiel C. Are, Babatunde S. Ewulo, Chioma M. Ahukaemere, Samuel O. Kolawole, Sunday E. Obalum

Applied Environmental Research

The soil remains the largest carbon sink, the capacity of which varies spatiotemporally and with anthropogenic activities, with implications for carbon dioxide (CO2) emissions and associated global warming. Despite the increasing popularity of organic amendments in the ecologically and anthropoculturally diverse farming systems of tropical Africa, manure-induced CO2 emissions in this region with high soil-carbon-sequestration potential are poorly documented. This study assessed seasonal CO2 emissions from poultry manure-amended sandy-clay-loam and sandy-loam soils in the Rainforest-Savannah and Southern Guinea Savannah zones, respectively, of Nigeria. Following manure application at 3 rates (0, 10, and 15 t ha-1), soil samples were collected during …

Fabrication Of Acid-Modified Corn Plant By-Product-Based Biochar For Efficient Adsorption Of Sulfamethoxazole From Aqueous Solutions, Thi An Hang Nguyen, Thi Duyen Le, Thi Hang Bui

Applied Environmental Research

Antibiotic pollution is of great interest owing to growing concerns about antibiotic resistance worldwide. This study aims to fabricate acid-modified biochar (CBM-A) from corn plant byproducts (CRs) for sulfamethoxazole (SMX) adsorption in aqueous solutions. CBM-A was synthesized via pyrolysis at 700 °C and modified with 14% H3PO4. Kinetics, isotherms, and thermodynamics were investigated in combination with material characterization to elucidate the adsorption behaviors and mechanisms. The results showed that pyrolysis and acid modification effectively enhanced SMX adsorption by CR because of the increased number of binding groups, specific surface area, and porosity. SMX adsorption on CBM-A was optimized at a …

Assessment Of Chromosomal Abnormalities In Hybrid Catfish In Reservoir Contaminated With Heavy Metals From Municipal Landfill, Tanadol Savigun, Natchanon Thiratanaboon, Nuttawadee Maneesan, Manop Sriuttha, Lamyai Neeratanaphan

Applied Environmental Research

In this study, the concentrations of heavy metals (As, Cd, Cr and Pb) in water, sediment, and hybrid catfish (Clarias gariepinus x C. macrocephalus) as well as chromosomal abnormalities (CAs) from a reservoir affected by leachate from a municipal landfill were compared to those in an unaffected reservoir. Heavy metal concentrations were analyzed using inductively coupled plasma‒optical emission spectrometry (ICP‒OES). Chromosomes were prepared from kidney cells by direct methods. The As, Cd and Pb concentrations in the water and sediment from both reservoirs were within the Thailand water and soil standards. The concentrations of As and Cd in the water …

Ammonium Adsorption From Aqueous Solutions Using Mnfe2o4-Functionalized Coffee Husk Biochar Nanocomposites : An Evaluation Of Hno3 And Naoh Activation, Thuy-Tien Do, Huu-Tap Van, Thi-Minh-Thu Nguyen

Applied Environmental Research

This research investigated the development of MnFe2O4-based composite adsorbents (MFO@CFA and MFO@CFB) by activating coffee husk-derived biochar with HNO3 and NaOH, followed by synthesis through coprecipitation and hydrothermal techniques. The structural and chemical properties of the nanocomposites were characterized by scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. Batch adsorption experiments were used to assess ammonium removal efficiency across a range of conditions: solution pH (3–8), contact time (5–120 min), adsorbent dosage (0.2–3 g L-1), and initial ammonium concentration (10–60 mg L-1). The findings indicated that compared with MFO@CFB, which was synthesized from NaOH-activated biochar, MFO@ CFA, derived …

Tree Composition And Carbon Sequestration Potential Of A University Campus In Bangkok, Thailand, Chaiwat Boonpeng, Pawanrat Butrid Butrid, Marisa Pischom, Satatip Noikrad

Applied Environmental Research

Trees play important roles in atmospheric carbon dioxide (CO2) absorption and climate change mitigation. The objective of this study was to assess tree characteristics and carbon sequestration potential at Ramkhamhaeng University (Hua Mak Campus), Bangkok, Thailand. Tree attributes, including species composition, abundance, diameter at breast height (DBH), and tree height, were recorded. Tree biomass, carbon storage, and CO2 sequestration were estimated using appropriate allometric equations. A total of 2,149 trees were recorded in the study area, corresponding to a tree density of 45.8 trees ha-1. The tree community was dominated by the palm family (Arecaceae), while Terminalia ivorensis was the …

Metal–Organic Frameworks : Opportunities And Challenges In Nutrient Recovery, Suchana Amnuaychaichana, Chi-Wang Li, Pongsak (Lek) Noophan, Sumeth Wongkiew

Applied Environmental Research

Nutrient recovery from waste streams is a critical strategy for promoting sustainable agriculture and mitigating environmental degradation. Essential nutrients commonly present in organic waste and wastewater, such as nitrogen and phosphorus, can be reclaimed and reintegrated into agricultural systems. Metal‒organic frameworks (MOFs), which are composed of metal clusters coordinated with organic ligands, have emerged as promising materials for adsorption and have the potential for nutrient recovery and pollutant removal because of their high porosity, large surface area, and tunable physicochemical properties. These attributes enable MOFs to serve in diverse applications, including heavy metal adsorption, organic pollutant degradation, and nutrient transformations. …

Data-Driven Prediction Of Compressive Strength In Pofa-Modified Concrete: A Comparative Study Of Lr, Nlr, And Ann Models, Shuaaib A. Mohammed, Hawdin Ismael Ibrahim, Diar Fatah Abdulrahman Askar, Hersh F Mahmood, Mehdi Khodaei, Soran Abdrahman Ahmad

Mansoura Engineering Journal

Production of concrete results in high CO₂ emissions, high energy demand, and consumption of various raw materials; however, it is one of the most widely used materials in construction to date. Therefore, researchers aim to minimize the impact of concrete production through various methods, such as introducing sustainable sources of materials that can be used in concrete. For instance, agricultural waste materials can be used as partial cement replacement. This study presents a comprehensive data-driven analysis of the effects of POFA on the properties of normal-strength concrete. By synthesizing a database of 196 experimental datasets from existing literature, three …

Recycling Of Plastic Into Fibers Using A Novel Machine Design And Analysis Of Fiber Characteristics, Mahmoud Khamees, Nasser Ayoub, Sabreen Addullah Abdelwahab, M. M. Maghawry

Mansoura Engineering Journal

This study presents a modified extrusion-based recycling system with an improved nozzle design and controlled fiber production capability. The machine was conceptualized and fabricated to efficiently process waste plastic and extrude it into fibers of varying diameters. The study focuses on evaluating how fiber diameter influences critical material properties. Microstructural analysis by scanning electron microscopy (SEM) was conducted to investigate the morphology and fiber diameters, while tensile testing provided insights into mechanical performance, including strength and elongation. Moisture absorption tests were also performed to assess durability and environmental resistance. The results demonstrate clear correlations between fiber diameter and the examined …

Federated And Explainable Spiking Neural Networks For Fair And Privacy-Preserving Nail Disease Diagnostics, Ch Pavani Reddy, Krishnanaik Vankdoth

Mansoura Engineering Journal

Automated nail disease diagnostics provide a non-invasive pathway for identifying underlying systemic health conditions; however, conventional centralized deep learning approaches often raise concerns related to privacy, fairness, and interpretability. Although the original NeuroNail-SNN framework demonstrated an energy-efficient and edge-ready diagnostic solution, its broader clinical adoption remained limited by unresolved trust, transparency, and ethical considerations. In this study, we propose the Federated and Explainable NeuroNail-SNN, which extends the original spiking neural architecture by integrating federated learning (FL), explainable artificial intelligence (XAI), fairness evaluation, and uncertainty quantification within a unified framework. Federated learning enables decentralized model training across hospitals and mobile clinics …

Optimisation Of Stepped Basin Solar Still With Response Surface Methodology And Machine Learning Methods, M. Balamurugan, V. Santhanam, B. Deepanraj, S. P Manikandan, M. Yuvaperiyasamy, N. Senthilkumar

Mansoura Engineering Journal

This research focuses on enhancing the distillate output of a stepped basin solar still by optimizing key operational variables using Response Surface Methodology (RSM) and advanced machine learning techniques. As water scarcity remains a critical global challenge, solar stills offer a viable, sustainable solution for desalination. These systems offer an energy-efficient approach to converting saline water intofreshwater, providing an alternative to conventional desalination methods. The primary objective was to investigate how variations in solar radiation, step height, and water inlet temperature influence the productivity of the stepped basin solar still. The solar radiation ranged from 600 to 1000 W/m², the …

Biomechanical Advancements In Hydroxyapatite, Magnesium-Substituted Hydroxyapatite, And Strontium-Substituted Hydroxyapatite In Clinical And Non-Clinical Studies For Maxillofacial Bone Tissue Engineering: A Review, Elham Zafarrazzaghnia, Stuart Hampshire, Aran Rafferty, Dermot Brabazon, Eamonn Debarra, Maura Kelleher

Articles

Hydroxyapatite (HA) is a bioceramic known for its bioactivity and osteoconductivity, which should make it an ideal candidate for maxillofacial bone regeneration. However, its brittleness limits its suitability for load-bearing applications. Over recent decades, substantial efforts have focused on enhancing its performance, particularly through ionic substitution, including magnesium-substituted HA (Mg-HA) and strontium-substituted HA (Sr-HA). This review summarises the available information on the structural, physical and mechanical properties of facial bones (maxilla, mandible, zygoma and frontal bone). The crystal structure, physical, and mechanical properties and in-vitro biological responses of dense and porous HA, Mg-HA and Sr-HA ceramics are described, with particular …

Automation And Habitat Development For A Space Based Marine Life Environment, Logan Trimmer, Alexander Hang

Harrisburg University Other Works

This project was a cross-collaboration between the Environmental Sciences and Advanced Manufacturing and Robotics programs for the company Monolith Space.

The goal of this project was to design an autonomous system to be able to track qualities of water in an aquaculture system designed to be sent to space.

Enhancing Deep Reinforcement Learning With Expert Demonstrations For Mobile Robot Navigation In Unstructured Off-Road Environments, Dulitha Dabare

Theses: Doctorates and Masters

Advancements in the field of Deep Learning has ushered in a boom in autonomous navigation research. Most of the work being conducted in this space, however, has focused on on-road urban navigation scenarios, with unstructured outdoor terrain navigation receiving much more limited attention. Given the wide range of applications that exist for legged and wheeled ground robots in off-road environments in areas such as agriculture, mining and disaster recovery, there is a growing need for research work to improve the navigational capabilities of mobile robots deployed in these challenging environments.

A promising candidate for application to these navigation challenges in …

General Approach To Determining The Embodied Energy Of Refractory Products, Jacob A. Kerr

Masters Theses

"Refractories are an important group of engineered materials that are critical for sustaining life in the modern age. These products are key components in many industrial processes, such as the production of steel, cement, glass, aluminum, copper, lead, and many others. It is estimated that 50 million tons of refractory products are produced and used around the world every year. Of this, an estimated 28 million tons of spent refractory is generated after use, much of which ends up in landfills all over the globe. By utilizing embodied energy methodologies, a complete sum of energy inputs can be mapped throughout …

Aura-Visionpose: Creating Datasets For Vision-Based Pose Estimation, Mohanad Alameer

Masters Theses

"Spacecraft rendezvous is an integral part of many orbital missions, including active space debris removal (ADR) and in-orbit servicing, assembly, and manufacturing (ISAM). Traditionally, rendezvous missions rely mainly on manual ground-based control to perform rendezvous and docking. While this can be effective on an individual basis, it becomes less practical at scale. Autonomous vision-based methods can reduce reliance on human control, and may improve scalability, response time, and reduce the possibility of human error for both ADR and ISAM. This work lays the necessary groundwork for developing a machine learning (ML) model for autonomous rendezvous by creating a labeled image …

Workshop Outcomes Report: 2nd International Workshop On Seismic Resilience Of Arctic Infrastructure And Social Systems, Majid Ghayoomi, Daniela Morganti

Faculty Publications

The report provides an overview of the second international workshop on Seismic Resilience of Arctic Infrastructure and Social Systems. The report discusses agenda, workshop activities, interdisciplinary working groups, and results. It ends with several strategic questions and investigation plans that were developed as part of the workshop activities.

Advancing Ultrahigh Carbon Steel Characterization: A Metaheuristic-Tuned Deep Learning Approach, Walaa Omar El-Farouk Badr, Hossam El-Din Mostafa, Rania Elbana

Mansoura Engineering Journal

Accurate classification of ultrahigh carbon steel (UHCS) microstructures is essential for elucidating processing-structure-property relationships and enhancing material performance. While convolutional neural networks (CNNs) offer powerful automated classification, navigating their complex, high-dimensional hyperparameter spaces present a significant computational bottleneck. To advance automated materials characterization, this study proposes a metaheuristic-tuned deep learning approach for robust and efficient microstructure classification. Two architectures, VGG16 and MobileNetV2, were evaluated under both pretrained and fine-tuned configurations, with Particle Swarm Optimization (PSO), Genetic Algorithm (GA), and Ant Colony Optimization (ACO) applied for systematic hyperparameter tuning. Results show that GA substantially improves the performance of fine-tuned VGG16, achieving …

Development Of Enhanced Dingo Optimization Algorithm For Distribution Network Reconfiguration, Samson Oladayo Ayanlade, Ignatius Kema Okakwu, Richard Oladayo Olarewaju, Ayodeji Akinsoji Okubanjo, Joseph Bukola Samson, Oluwadare Adepeju Adebisi, Emmanuel Idowu Ogunwole, Oluwadare Olatunde Akinrogunde

Mansoura Engineering Journal

This paper presents the Enhanced Dingo Optimization Algorithm (EDOA) to reconfigure the radial distribution network with the long-standing problem of active power loss minimization while maintaining a stable and acceptable voltage profile. EDOA enhances the standard Dingo Optimization Algorithm (DOA) through the integration of adaptive search control, elite-guided local refinement, and crossover-based diversity preservation mechanisms tailored for distribution network reconfiguration problems. The proposed method has been tested on two test systems: the IEEE 33-bus standard as well as the real-world Ayepe 34-bus distribution feeder in Ibadan, Nigeria. In the IEEE 33-bus test system, EDOA reduces active power loss by 56.00%; …

Finite Element Analysis Of Oxygen Transport In Tissue And Capillaries With A Second Order Metabolic Consumption, Vikash Ramcharitar, Sreedhara Rao Gunakala, Reddappa Bandi, Donna M. G. Dyer, Jagdesh Ramnanan

Mansoura Engineering Journal

This study presents a numerical investigation into the oxygen transport through a Krogh-type capillary-tissue model with second-order tissue metabolism. The governing non-linear equations are solved by implementing a Galerkin finite element method with a fixed-point iteration scheme. The resulting code and solution algorithm were successfully validated against available analytical solutions for zeroth- and first-order kinetics, showing very good agreement. Numerical simulations indicated, that under the parameters investigated, relative to zeroth- and first-order kinetics, a second-order metabolism leads to less overall oxygen consumption within the tissue phase. This yields higher oxygen partial pressures at the outer tissue boundary and higher oxygen …