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Optimization Of A Tri-Layered Vascular Graft: The Influence Of Cellular And Mechanical Properties, Michael Mcclure Jun 2011

Optimization Of A Tri-Layered Vascular Graft: The Influence Of Cellular And Mechanical Properties, Michael Mcclure

Theses and Dissertations

Electrospinning is a polymer processing technique which allows for the production of nano to micro size fibers and scaffolds which can be composed of numerous synthetic biodegradable materials and natural biopolymers. Natively, elastin and collagen are the main components of vascular tissue. Arranged in a tri-layered structure, they create a specific mechanical environment that can withstand the rigors of circulation. The goal of this study was to develop a mechanically ‘biomimicking’ vascular graft composed of three distinct layers through the process of electrospinning. We hypothesize that the use of bioactive agents such as elastin, collagen, and silk to supplement poly(caprolactone) …


Solar Warning Architecture For Manned Missions To Mars, James S. Bohren, John K. Howard Jun 2011

Solar Warning Architecture For Manned Missions To Mars, James S. Bohren, John K. Howard

Theses and Dissertations

Solar radiation storms represent a dire threat to manned interplanetary space travel. Earth's current solar forecasting architecture is Earth-focused and insufficient to provide timely warnings to a manned mission to Mars, therefore a "best value" solar warning architecture must be identified. A total of 14 solar warning architectures were developed by varying 5 solar sensor locations, 2 processing locations, and 2 communications strategies. Using Satellite Tool Kit, performance of the candidate architectures in terms of Warning Time and Solar Coverage was quantified during a Mars mission scenario based on NASA's Design Reference Architecture 5.0. Cost of each candidate architecture was …


Characterizing Cyclostationary Features Of Digital Modulated Signals With Empirical Measurements Using Spectral Correlation Function, Mujun Song Jun 2011

Characterizing Cyclostationary Features Of Digital Modulated Signals With Empirical Measurements Using Spectral Correlation Function, Mujun Song

Theses and Dissertations

Signal detection is widely used in many applications. Some examples include Cognitive Radio (CR) and military intelligence. CRs use signal detection to sense spectral occupancy. Without guaranteed signal detection, a CR cannot reliably perform its role. Similarly, signal detection is the first step for garnering an opponent's information. Wireless signal detection can be performed using many different techniques. Some of the most popular include matched filters, energy detectors (which use measurements such as the Power Spectral Density (PSD) of the signal), and Cyclostationary Feature Detectors (CFD). Among these techniques, CFD can be viewed as a compromise technique, in that it …


Use Of Remote Sensing To Support Forest And Wetlands Policies In The Usa, Audrey L. Mayer, Ricardo D. Lopez Jun 2011

Use Of Remote Sensing To Support Forest And Wetlands Policies In The Usa, Audrey L. Mayer, Ricardo D. Lopez

College of Forest Resources and Environmental Science Publications

The use of remote sensing for environmental policy development is now quite common and well-documented, as images from remote sensing platforms are often used to focus attention on emerging environmental issues and spur debate on potential policy solutions. However, its use in policy implementation and evaluation has not been examined in much detail. Here we examine the use of remote sensing to support the implementation and enforcement of policies regarding the conservation of forests and wetlands in the USA. Specifically, we focus on the “Roadless Rule” and “Travel Management Rules” as enforced by the US Department of Agriculture Forest Service …


Use Of Imaging Biomarkers To Assess Perfusion And Glucose Metabolism In The Skeletal Muscle Of Dystrophic Mice, Nabeel Ahmad, Ian Welch, Robert Grange, Jennifer Hadway, Savita Dhanvantari, David Hill, Ting-Yim Lee, Lisa M Hoffman Jun 2011

Use Of Imaging Biomarkers To Assess Perfusion And Glucose Metabolism In The Skeletal Muscle Of Dystrophic Mice, Nabeel Ahmad, Ian Welch, Robert Grange, Jennifer Hadway, Savita Dhanvantari, David Hill, Ting-Yim Lee, Lisa M Hoffman

Robarts Imaging Publications

BACKGROUND: Duchenne muscular dystrophy (DMD) is a severe neuromuscular disease that affects 1 in 3500 boys. The disease is characterized by progressive muscle degeneration that results from mutations in or loss of the cytoskeletal protein, dystrophin, from the glycoprotein membrane complex, thus increasing the susceptibility of contractile muscle to injury. To date, disease progression is typically assessed using invasive techniques such as muscle biopsies, and while there are recent reports of the use of magnetic resonance, ultrasound and optical imaging technologies to address the issue of disease progression and monitoring therapeutic intervention in dystrophic mice, our study aims to validate …


Development Of Wearable Sensors For Body Joint Angle Measurement, Saba Bakhshi Khayani Jun 2011

Development Of Wearable Sensors For Body Joint Angle Measurement, Saba Bakhshi Khayani

Electronic Theses and Dissertations

This thesis presents the development of three different methods for body joint angle measurement using wearable sensors. Continuous monitoring of patients' movements and activities has recently become one of the active research areas in the field of body sensor network and telehealth monitoring. For many medical and rehabilitation applications, a continuous monitor of the patients' daily activities at home without visiting the hospital is desirable. This type of monitoring is beneficial for the therapists and physicians as it does not require patients' physical presence. Traditionally, measuring the range of motion (ROM) is performed in hospitals by utilizing standard tools such …


Human Factor And Ergonomic Considerations And Improvements For A Table-Free Card Game Product, Enrique Daniel Aguirre Jun 2011

Human Factor And Ergonomic Considerations And Improvements For A Table-Free Card Game Product, Enrique Daniel Aguirre

Industrial and Manufacturing Engineering

The purpose of this project is to design a table-free Yu-Gi-Oh! Card Game product that will make the transition of said game from table to user more fluid and intuitive, improving on past designs in the process. Despite there currently being many similar products in the market, there has not yet been one that adequately fulfills game requirements and comfortably adapts to the range of players associated with the game. Taking ergonomic and human factor considerations into account during the development of the design, a prototype was created as part of this project that was subsequently tested against a past …


Materials Characterization Of Bamboo And Analysis Of Bonding Strength And Internal Strength As A Structural Member In Reinforced Concrete, Nithi Plangsriskul, Nicholas Dorsano Jun 2011

Materials Characterization Of Bamboo And Analysis Of Bonding Strength And Internal Strength As A Structural Member In Reinforced Concrete, Nithi Plangsriskul, Nicholas Dorsano

Materials Engineering

This study evaluates the potential to utilize bamboo as reinforcement in concrete structural members.  In this project, the mechanical properties of bamboo were tested, specifically force required to embed a 0.5” diameter ball 0.016” into the bamboo samples and its bonding strength with concrete.  One type of bamboo, Bambusa Oldhamii, was cut into eight sections, approximately 2.54 cm wide, along the length of the culm.  The compression test recorded the bamboo’s strength at eight points along the length of the internode and at three points along the transverse direction of each specimen.  Bambusa Oldhamii’s specimen base 1 data for inner, …


Olympic Bocce Ballers, Steven Erickson, William Haley, Taylor Vaughan Jun 2011

Olympic Bocce Ballers, Steven Erickson, William Haley, Taylor Vaughan

Mechanical Engineering

No abstract provided.


Piedras Blancas Light Station Vista Point Improvement Plan, Larissa Heeren, Reuben Juster, Annamarie Usher, John Rossi, Nick Mitchell Jun 2011

Piedras Blancas Light Station Vista Point Improvement Plan, Larissa Heeren, Reuben Juster, Annamarie Usher, John Rossi, Nick Mitchell

Mechanical Engineering

Piedras Blancas Light station Improvement Involved the design of two separate parking lot/vista point plans as well as the creation of a concrete Iron Ranger located near the gift shop on site.


Edapts Web Application Redesign With Route Editor And Dynamic Frontend, John O'Connor, Aaron Berk Jun 2011

Edapts Web Application Redesign With Route Editor And Dynamic Frontend, John O'Connor, Aaron Berk

Computer Engineering

The EDAPTS (Efficient Deployment of Advanced Public Transportation Systems) system is designed to facilitate the public transportation system, making it even easier for San Luis Obispo residents and guests to use. We have upgraded the web component of the system adding a tool that makes it simple for non-programmers to add, edit, and delete routes. Furthermore, we have modified the front end web code to read from a central MySQL database containing all the route information created using the new, user-friendly tool.


Characterization Of A Dual Acoustic Receiver System For Measuring Range And Bearing To Acoustic Tags, Victoria Campana, Justin Knight Jun 2011

Characterization Of A Dual Acoustic Receiver System For Measuring Range And Bearing To Acoustic Tags, Victoria Campana, Justin Knight

Computer Engineering

Experiements were performed to determine the effectiveness of the Lotek RT-A Hydrophone system and if it could provide the data necessary for a particle filter to determine the location of a shark. Over the period of a few months, we tested off the Cal Poly Pier at set GPS coordinates to characterize how accurately the Lotek System can determine range and orientation. Ranges from 0-500 meters were tested with the Lotek system being in a stationary position and Lotek receiver tag being put at specified GPS coordinates. The two hydrophone rigging was then rotated a full 360 degrees to gauge …


Myrrrrr's Dice Game Android Application, Craig Leitterman Jun 2011

Myrrrrr's Dice Game Android Application, Craig Leitterman

Computer Engineering

Smartphones are one the newest and fastest growing hardware platforms in recent years. The number of users playing and downloading games on the Android and iPhone application markets are growing rapidly. A majority of users including myself have been known to play common retro games such as solitaire as well as newer flash games like Angry Birds. These titles are usually “pick up and play” and provide quick entertainment while you’re waiting for the bus or in between a work break. Given the huge popularity of these applications I decided to create a dice game that I used to play …


Measuring The Nanoindentation Properties Of Alendronate-Time Treated Canine Cortical, Folorunso Ashaolu Jun 2011

Measuring The Nanoindentation Properties Of Alendronate-Time Treated Canine Cortical, Folorunso Ashaolu

Master's Theses

This study examines the nanoindentation (energy inclusive) properties of 0.2 mg/kg alendronate treated ribs at one and three years against a vehicle treated control in a fresh-frozen, non-cold-mounted, condition.  This was to verify if the tissue-level properties for 0.2 ALN treated beagles would increase because of an increased level of mineralization despite a microdamage increase.

A total of twelve (12) skeletally mature (1–2 years old) female beagle dogs were treated daily for three years and one year with oral doses of vehicle (VEH, 1 mL/kg saline) or alendronate (ALN, 0.2 Merck, Rahway, NJ). The 0.2 mg dose corresponds, on a …


Ischemia Impairs Vasodilation In Skeletal Muscle Resistance Artery, Kyle Remington Struthers Jun 2011

Ischemia Impairs Vasodilation In Skeletal Muscle Resistance Artery, Kyle Remington Struthers

Master's Theses

Functional vasodilation in arterioles is impaired with chronic ischemia. We sought to examine the impact of chronic ischemia and age on skeletal muscle resistance artery function. To examine the impact of chronic ischemia, the femoral artery was resected from young (2-3mo) and adult (6-7mo) mice and the profunda femoris artery diameter was measured at rest and following gracilis muscle contraction 14 days later using intravital microscopy. Functional vasodilation was significantly impaired in ischemic mice (14.4±4.6% vs. 137.8±14.3%, p<0.0001 n=8) and non-ischemic adult mice (103.0±9.4% vs. 137.8±14.3%, p=0.05 n=10). In order to analyze the cellular mechanisms of the impairment, a protocol was developed to apply pharmacological agents to the experimental preparation while maintaining tissue homeostasis. Endothelial and smooth muscle dependent vasodilation were impaired with ischemia, 39.6 ± 13.6% vs. 80.5 ± 11.4% and 43.0 ± 11.7% vs. 85.1 ± 10.5%, respectively. From this data, it can be supported that smooth muscle dysfunction is the reason for the observed impairment in arterial vasodilation.


A Frequency-Modulated Continuous Wave-Based Boundary Detection System For Determination Of Monitoring Region For An Indoor Ultra-Wideband Short Range Radar-Based Eldercare Monitoring System, Wilson Tang Jun 2011

A Frequency-Modulated Continuous Wave-Based Boundary Detection System For Determination Of Monitoring Region For An Indoor Ultra-Wideband Short Range Radar-Based Eldercare Monitoring System, Wilson Tang

Master's Theses

Falls are a cause of concern for the elderly since it can render a person immobile. A monitoring system can summon immediate aid by the automatic detection of fall events. The application of ultra-wideband (UWB) signals for a monitoring system was chosen due to its unique characteristics such as wide spectrum, immunity to interference, penetrability, and application for the detection of people. Part of this monitoring system is boundary detection with the purpose of isolating the location of fall events and to function as a mask to define an area of interest. A study of various localizing methods using measurements …


Groundwater Research In Middle Earth, Thomas Lapoint Jun 2011

Groundwater Research In Middle Earth, Thomas Lapoint

Liberal Arts and Engineering Studies

My senior project focused on studying saltwater intrusion in a coastal town of New Zealand. I feel lucky that I was able to travel to such a distant place, conduct research that was insightful and interesting, and immerse myself in an international culture all in the name of my education. As a Liberal Arts and Engineering Studies student, I aim to analyze not only the cultural differences and similarities that the foreign environment offers to me but also the detailed, technical, engineering aspect of my research. I believe that my education should be approached with a well rounded perspective that …


Byu Indoor Flight System Circa June 2011, John C. Macdonald, Robert Leishman Jun 2011

Byu Indoor Flight System Circa June 2011, John C. Macdonald, Robert Leishman

Faculty Publications

This report documents the state of our indoor flight platform as of June 2011, the time of its first flight without a human in the loop. The report is intended to give enough detail that someone might have a reasonable hope of replicating our work from scratch.


Autonomous Crash Avoidance System, Brian Ujiie, Gordon Woods, Joshua Miller Jun 2011

Autonomous Crash Avoidance System, Brian Ujiie, Gordon Woods, Joshua Miller

Mechanical Engineering

No abstract provided.


Photovoltaic System Design For Dc House, Luis B. Perez, Hao Ming Mai Jun 2011

Photovoltaic System Design For Dc House, Luis B. Perez, Hao Ming Mai

Electrical Engineering

The objective of this project is to research and design a practical 200W photovoltaic system at the lowest cost and highest efficiency in order to support the DC House Project. The impetus for this project stems from the necessity of delivering energy to people in developing countries who otherwise lack the benefits of electricity. The Photovoltaic System Design is divided into two main parts, the buck DC-DC converter and the optimized photovoltaic panel. The converter consists of schematics, efficiency calculations, load/line regulation calculations, component comparisons, data plots from simulations and testing. The optimized photovoltaic panel section includes component comparisons, complete …


Machine Design Lab: Using Automotive Transmission Examples To Reinforce Understanding Of Gear Train Analysis, Roger A. Beardsley, Charles O. Pringle Jun 2011

Machine Design Lab: Using Automotive Transmission Examples To Reinforce Understanding Of Gear Train Analysis, Roger A. Beardsley, Charles O. Pringle

Engineering Technologies, Safety, and Construction Faculty Scholarship

In studying mechanical gear train analysis, some students struggle with relatively simple gear design concepts, and virtually all have difficulty with the complexities of planetary gear sets. This paper describes two labs developed for an undergraduate senior level machine design course. One lab uses a three-speed manual synchromesh transmission with parts of the case cut away to demonstrate the operation of the gears, shifting mechanism, bearings, and other aspects of the design. Students then count teeth and analyze the gear ratios using standard gear train analysis methods. The other lab uses a 1924 Ford Model T planetary transmission to observe …


Using Service Responsibility Tables To Supplement Uml In Analyzing E-Service Systems, Xin Tan, Steven Alter, Keng Siau Jun 2011

Using Service Responsibility Tables To Supplement Uml In Analyzing E-Service Systems, Xin Tan, Steven Alter, Keng Siau

Research Collection School Of Computing and Information Systems

This paper proposes using Service Responsibility Tables (SRTs) as a tool in analyzing e-service systems. First it discusses difficulties and deficiencies of using formal modeling languages such as UML in analyzing e-service systems. It proposes using SRTs as an informal language and lightweight analytical tool to be used by business professionals in analyzing e-service systems. SRTs are based on a service value chain framework but do not rely on abstract concepts and constructs, and therefore can be used by business professionals to supplement UML. We suggest a set of heuristics for transforming SRTs into two key UML diagrams, thereby illustrating …


Distributed Learning With Biogeography-Based Optimization, Carre Scheidegger, Arpit Shah, Daniel J. Simon Jun 2011

Distributed Learning With Biogeography-Based Optimization, Carre Scheidegger, Arpit Shah, Daniel J. Simon

Electrical and Computer Engineering Faculty Publications

We present hardware testing of an evolutionary algorithm known as biogeography-based optimization (BBO) and extend it to distributed learning. BBO is an evolutionary algorithm based on the theory of biogeography, which describes how nature geographically distributes organisms. We introduce a new BBO algorithm that does not use a centralized computer, and which we call distributed BBO. BBO and distributed BBO have been developed by mimicking nature to obtain an algorithm that optimizes solutions for different situations and problems. We use fourteen common benchmark functions to obtain results from BBO and distributed BBO, and we also use both algorithms to optimize …


A Neural Network Receiver For Em-Mwd Communication, Timothy P. Whitacre Jun 2011

A Neural Network Receiver For Em-Mwd Communication, Timothy P. Whitacre

Master's Theses

Baseband digital communication in electro-magnetic measurement while drilling (EM-MWD) systems is often corrupted by non-white surface noise. The inability to reliably decode the transmitted signals in a noisy environment limits the depth at which EM-MWD systems can operate. Correlation receivers, which are optimal in the presence of additive white Gaussian noise, can be sub-optimal in the presence of various types of field noise at different drilling sites.

This thesis investigates the application of artificial neural networks (ANN) as communication receivers in EM-MWD baseband digital communication systems. The performances of various ANN architectures and training algorithms are studied and compared with …


Active Pen Input And The Android Input Framework, Andrew S. Hughes Jun 2011

Active Pen Input And The Android Input Framework, Andrew S. Hughes

Master's Theses

User input has taken many forms since the conception of computers. In the past ten years, Tablet PCs have provided a natural writing experience for users with the advent of active pen input. Unfortunately, pen based input has yet to be adopted as an input method by any modern mobile operating system. This thesis investigates the addition of active pen based input to the Android mobile operating system.

The Android input framework was evaluated and modified to allow for active pen input events. Since active pens allow for their position to be detected without making contact with the screen, an …


Studying Milk Coagulation Kinetics With Laser Scanning Confocal Microscopy, Image Processing, And Computational Modeling, Richard Joseph Hennessy Jun 2011

Studying Milk Coagulation Kinetics With Laser Scanning Confocal Microscopy, Image Processing, And Computational Modeling, Richard Joseph Hennessy

Master's Theses

The kinetics of milk coagulation are complex and still not well understood. A deeper understanding of coagulation and the impact of the relevant factors would aid in both cheese manufacturing and also in determining the nutritional benefits of dairy products. A method using confocal microscopy was developed to follow the movement of milk fat globules and the formation of a milk protein network during the enzyme-induced coagulation of milk. Image processing methods were then used to quantify the rate of coagulation. It was found that the texture of the protein network is an indicator of the current status of the …


Characterization And Implementation Of A Decellularized Porcine Vessel As A Biologic Scaffold For A Blood Vessel Mimic, Aubrey N. Smith Jun 2011

Characterization And Implementation Of A Decellularized Porcine Vessel As A Biologic Scaffold For A Blood Vessel Mimic, Aubrey N. Smith

Master's Theses

Every 34 seconds, someone in the United States suffers from a heart attack.  Most heart attacks are caused by atherosclerotic build up in the coronary arteries, occluding normal blood flow.  Balloon angioplasty procedures in combination with a metal stent often result in successful restoration of normal blood flow.  However, bare metal stents often lead to restenosis and other complications.  To compensate for this problem, industry has created drug-eluting stents to promote healing of the artery wall post stenting.  These stents are continually advancing toward better drug-eluting designs and methods, resulting in a need for fast and reliable pre-clinical testing modalities. …


Development Of An In-Vitro Hyperglycemic Tissue Engineered Blood Vessel Mimic, Brian C. Wong Jun 2011

Development Of An In-Vitro Hyperglycemic Tissue Engineered Blood Vessel Mimic, Brian C. Wong

Biomedical Engineering

No abstract provided.


Enhancing Undergraduate Engineering Education Of Lean Methods Using Simulation Learning Modules Within A Virtual Environment, Elizabeth A. Cudney, Steven Corns, Jennifer A. Farris, Stephen Gent, Scott Erwin Grasman, Ivan G. Guardiola Jun 2011

Enhancing Undergraduate Engineering Education Of Lean Methods Using Simulation Learning Modules Within A Virtual Environment, Elizabeth A. Cudney, Steven Corns, Jennifer A. Farris, Stephen Gent, Scott Erwin Grasman, Ivan G. Guardiola

Engineering Management and Systems Engineering Faculty Research & Creative Works

This paper highlights the use of an integrated user-centered virtual learning environment throughextensible simulation learning modules that is currently being developed to enhance undergraduate curricula to meet the industrial needs for engineers with education in lean. The purpose of the research is to address these expectations by developing learning modules that incorporate lean simulation models into various Engineering Management, Industrial Engineering, and Mechanical Engineering courses at Missouri S&T, Texas Tech, and South Dakota State, respectively. In recent years, increasing global competition, rapidly changing technology, and a deficit of U.S. engineering graduates have intensified the need to produce graduating engineers who …


A Microfluidic Culture For Two Populations Of Dorsal Root Ganglia For Differential Staining, Ishnoor Sidhu May 2011

A Microfluidic Culture For Two Populations Of Dorsal Root Ganglia For Differential Staining, Ishnoor Sidhu

Theses

The goal of this study was to design and fabricate a microfluidic system that can be used to visibly distinguish the two populations of dorsal root ganglia (DRGs) by differential staining. Polydimethylsiloxane (PDMS) is the most widely used silicon-based organic polymer, and is particularly known for its wide spread use in microfluidics. Various methods have been employed to pump fluids in these channels for applications ranging from patterning of cells and biomolecules to control of local environment factors such as temperature, which requires external pumping or other applied forces. We demonstrated a pump-free device that exploits the surface energy stored …