Digital Commons Network^™

A Sociotechnical Systems-Based Process To Facilitate The Development Of A Change Intervention Deployment Plan, Jorge Luis Nadal

EMSE Doctoral Projects

The purpose of this project was to formulate a process to facilitate the development of an effective change intervention deployment plan. The premise is that without a proper deployment plan, the successful implementation of a change intervention in an organization will be slow and require multiple revisions. This research utilized a Sociotechnical Systems (STS) approach to analyze the implementation of a major change intervention.

This research was in part prompted by a request by management of the U.S. Army Corps of Engineers (USACE) for the researcher to examine why it has taken so long to successfully implement this large-scale change …

Metal-Based Nanoparticle Interactions With The Nervous System: The Challenge Of Brain Entry And The Risk Of Retention In The Organism, Robert A. Yokel, Eric A. Grulke, Robert C. Macphail

Pharmaceutical Sciences Faculty Publications

This review of metal-based nanoparticles focuses on factors influencing their distribution into the nervous system, evidence they enter brain parenchyma, and nervous system responses. Gold is emphasized as a model metal-based nanoparticle and for risk assessment in the companion review. The anatomy and physiology of the nervous system, basics of colloid chemistry, and environmental factors that influence what cells see are reviewed to provide background on the biological, physical–chemical, and internal milieu factors that influence nervous system nanoparticle uptake. The results of literature searches reveal little nanoparticle research included the nervous system, which about equally involved in vitro and in …

Hip Proprioceptors Preferentially Modulate Reflexes Of The Leg In Human Spinal Cord Injury, Tanya Onushko, Allison S. Hyngstrom, Brian D. Schmit

Biomedical Engineering Faculty Research and Publications

Stretch-sensitive afferent feedback from hip muscles has been shown to trigger long-lasting, multijoint reflex responses in people with chronic spinal cord injury (SCI). These reflexes could have important implications for control of leg movements during functional activities, such as walking. Because the control of leg movement relies on reflex regulation at all joints of the limb, we sought to determine whether stretch of hip muscles modulates reflex activity at the knee and ankle and, conversely, whether knee and ankle stretch afferents affect hip-triggered reflexes. A custom-built servomotor apparatus was used to stretch the hip muscles in nine chronic SCI subjects …

Zein: Novel Natural Polymer For Nanoparticle- And Film-Mediated Gene Delivery, Jessica D. Taylor

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Gene delivery, the introduction of DNA into cells, is applicable to gene therapy, DNA vaccination, functional genomics and diagnostics, tissue engineering, and drug-eluting medical devices. Particulates incorporating DNA are promising vehicles for gene delivery and overcome some of the barriers that hinder successful gene transfer, with the ability to protect DNA and provide for controlled, localized, and sustained release and transfection. Furthermore, innovative new gene delivery strategies that incorporate DNA particulates or complexes within films or coatings for devices and scaffolds could further provide for controlled and sustained transfection at the site of implant. Zein, a hydrophobic protein from corn, …

Metamaterial Enhanced Wireless Power Transmission System, Travis Jade Heffernan

Master's Theses

Nikolai Tesla's revolutionary experiments demonstrated the possible benefits of transmitting power wirelessly as early as 1891. Applications for the military, consumers, emergency personnel, remote sensors, and others use Tesla’s discovery of wireless power. Wireless power transmission (WPT) has the potential to be a common source of consumable energy, but it will only receive serious consideration if the transmit and receive systems are extremely efficient and capable of delivering usable amounts of power. Research has been conducted to improve the efficiency and performance of nearly every aspect of WPT systems, but the relatively new field of metamaterials (MTMs) has yet to …

The Effect Of The Probiotic Pediococcus Acidilactici On The Gut Microbiota Ecology Of Rainbow Trout (Oncorhynchus Mykiss Walbaum) Analysed Using Dgge, Alice Anderson

The Plymouth Student Scientist

The microbiota of the gastrointestinal tract heavily influences the health, growth and survival of fish. Probiotics have proved effective in improving fish productivity in aquaculture. Research suggests that probiotics, supplemented in the feed, may elicit these benefits by altering the ecology of the gastrointestinal microbiota. The probiotic Pediococcus acidilactici has been successfully used for terrestrial animals and humans but its use in aquatic organisms has been less researched. In the present study, rainbow trout Oncorhynchus mykiss (Walbaum) were fed a diet that contained Ped. Acidilactici, or a control diet. Analysis of the posterior digesta bacteria, using a non-culture dependant technique, …

Osmotic Regulation Of The Amphipod Gammarus Chevreuxi (Sexton, 1912), Sam Houston

The Plymouth Student Scientist

This study investigated osmotic regulation in the amphipod, Gammarus chevreuxi, and is the first publication of this organism’s osmotic regulatory curves. Unlike most estuarine amphipods studied to date which are hyperosmotic regulators, G. chevreuxi is a hyper-hyposmotic regulator. The hyperosmotic gradient maintained by G. chevreuxi in dilute media is very low (~120mmol.L-1), which has been interpreted as evidence of freshwater ancestry among the Crustacea. Salinity acclimation did not appear to affect heart rate or pleopod beat frequency. The gill cells responsible for ion uptake appeared to be smaller in high salinities or distorted. The apical membrane in concentrated media shows …

Plastic Response Of Dislocation Glide In Solid Helium Under Dc Strain-Rate Loading, Caizhi Zhou, Jungjung Su, Matthias J. Graf, Charles J. Olson Reichhardt, Alexander V. Balatsky, Irene J. Beyerlein

Materials Science and Engineering Faculty Research & Creative Works

We develop a model for the gliding of dislocations and plasticity in solid ⁴He. This model takes into account the Peierls barrier, multiplication and interaction of dislocations, as well as classical thermally and mechanically activated processes leading to dislocation glide. We specifically examine the dc stress-strain curve and how it is affected by temperature, strain rate, and dislocation density. As a function of temperature and shear strain, we observe plastic deformation and discuss how this may be related to the experimental observation of elastic anomalies in solid hcp ⁴He that have been discussed in connection with the possibility …

An Fmri Study On Supra-Spinal Contributions To Upper And Lower Limb Motor Control, Shancheng Bao

Master's Theses (2009 -)

The differences in the neural mechanisms contributing to upper and lower extremity movement have not been fully elucidated, and this might be a factor that leads to the ineffectiveness of rehabilitation techniques for most stroke survivors. It is unclear whether therapies designed for upper extremities should also be used for the lower extremities, and vice versa. In this study, fMRI was used to examine the supraspinal control of UE and LE movement in both neurologically intact individuals and people with post-stroke hemiparesis. We compared the location, volume, and intensity of brain activity associated with upper and lower extremity pedaling and …

A Multi-Configuration Display Methodology Incorporating Reflection For Real-Time Haptic-Interactive Virtual Environments, Mohammad F. Obeid

Computational Modeling & Simulation Engineering Theses & Dissertations

There is a natural need for real-time min-or reflection in many interactive virtual reality applications to achieve visuo-haptic collocation through optical reflection. Its use, however, calls for adjustments to the original model since a mirror reverses image characteristics. This thesis introduces a design and implementation of a generic configuration component for virtual environments that adjusts image characteristics and haptic interfaces to accommodate various display setups while preserving the correct orientation and properties of the original models in the graphical scene. Four different but related approaches were developed for image connection and are compared and contrasted against primary criteria. The haptic …

Optical Imaging Of Lipopolysaccharide-Induced Oxidative Stress In Acute Lung Injury From Hyperoxia And Sepsis, Reyhaneh Sepehr, Said H. Audi, Sepideh Maleki, Kevin Staniszewski, Annie L. Eis, Girija G. Konduri, Mahsa Ranji

Biomedical Engineering Faculty Research and Publications

Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants. Bacterial infection and oxygen toxicity, which result in pulmonary vascular endothelial injury, contribute to impaired vascular growth and alveolar simplification seen in the lungs of premature infants with BPD. Hyperoxia induces ALI, reduces cell proliferation, causes DNA damage and promotes cell death by causing mitochondrial dysfunction. The objective of this study was to use an optical imaging technique to evaluate the variations in fluorescence intensities of the auto-fluorescent …

Gas Leakage Detection System (Glds), Daudi Simbeye

Tanzania Journal of Engineering and Technology (TJET)

This paper mainly focuses on the detection of gas leakage and providing security when the user is around or away from home. The system is Short Message Service (SMS) based and uses wireless technology for providing security against gas leakage to users hence cost effective and more adaptable. The system comprises of sensors for detecting gas leak interfaced to microcontroller that will give an alert to user whenever there is a gas leakage, display warning information by using Liquid Crystal Display (LCD), sending SMS to the user for notification wherever he/she might be and turning off electric power with the …

Isolation And Characterisation Of Micro-Organisms With Industrial Importance From Sisal Bole Rots, Consolatha Mhaiki

Tanzania Journal of Engineering and Technology (TJET)

Investigation of microorganisms naturally acclimatized to Agave hybrid H 11648 (sisal bole rot) was conducted, with the aim of isolating and characterizing Aspergillus niger strains for industrial use. Microorganism were identified morphologically and then confirmation made by polymerase chain reaction (PCR). Results showed the existence of four major groups, listed in order of abundances as follows; Aspergilli (36.0±0.8) %, Penicillin (28.0±0.1) %, Yeast (15.0±1.6) %and Fusarium (10.0±0.12) %. The main groups of Aspergilli strains were A. nidulans, A. tamari and A. niger in ratios (3:2:2), respectively. Several endo-spore forming non-enteric gram (-) rods and coccid bacteria identified by API 20 …

Apparatus And Method For Growing Biological Organisms For Fuel And Other Purposes, David J. Bayless, Morgan Lefay Vis-Chiasson, Ben J. Stuart, Gregory G. Kremer

Mechanical and Aerospace Engineering Faculty Research & Creative Works

A bioreactor apparatus in which a container has sidewalls, a floor and a ceiling defining a chamber that contains a slurry of water, nutrients and photosynthetic microorganisms. A plurality of optical fibers, each of which has a first end disposed outside the chamber and a second end in the mixture. A light collector spaced from the container has light incident on it and focuses the light onto the first ends of the plurality of optical fibers, thereby permitting the light to be conveyed into the mixture to promote photosynthesis. At least one nozzle is in fluid communication with a source …

Experiments With Gmti Radar Using Micro-Doppler, Benjamin Walter Dilsaver

Theses and Dissertations

As objects move, their changing shape produces a signature that can be measured by a radar system. That signature is called the micro-Doppler signature. The micro-Doppler signature of an object is a distinguishing characteristic for certain classes of objects. In this thesis features are extracted from the micro-Doppler signature and are used to classify objects. The scope of the objects is limited to humans walking and traveling vehicles. The micro-Doppler features are able to distinguish the two classes of objects. With a sufficient amount of training data, the micro-Doppler features may be used with learning algorithms to predict unknown objects …

Curriculum Exchange: Visualization Tools And Online Courses For Teaching About Earthquakes, Sandra Seale, Thalia Anagnos

Faculty Publications

As part of a national consortium of universities practicing and doing research in earthquake engineering, our site has developed several videos for use in outreach and education. Visualization tools are extremely useful when teaching about how earthquakes shake the ground and the response of buildings to that shaking. Here we present videos that are targeted to specific audiences: (1) Animations of the response of two model buildings to two earthquakes are targeted at grade 6-16 students. The videos were created with data recorded on these test structures from the two earthquakes. The two events were both located directly below the …

Scale-Up Of Bubble Column Reactors: A Review Of Current State-Of-The-Art, Ashfaq Shaikh, Muthanna H. Al-Dahhan

Chemical and Biochemical Engineering Faculty Research & Creative Works

In Multiphase Flow Reaction Systems, in General, an Extrapolation of Small Diameter Behavior to Larger Ones is Always an Important and Challenging Task. the Critical Issue in Such an Extrapolation Remains to Be Mixing and Hydrodynamic Characteristics. It Needs Reliable Similarity Criteria that Would Result in Similar Mixing and Hydrodynamics and Hence Transport and Performance in Two Different Scales. Numerous Experimental and Computational Studies Have Been Performed to Investigate the Flow Behavior of Bubble Column Reactors for a Proper Design and Scale-Up. Experimental Techniques Vary from Simple Visual Observation to More Advanced Noninvasive Diagnostic Techniques. on Computational Front the Progress …

An Industrial Demonstration Of Biorefinery Of Lipids:Coproduction Of Biodiesel And 1,3-Propandiol, Dehua Liu

BioEnergy IV: Innovations in Biomass Conversion for Heat, Power, Fuels and Chemicals

No abstract provided.

Producing Hydrocarbon Drop-In Biofuelsfrom Cellulosic Materials, Birgitte Ahring

BioEnergy IV: Innovations in Biomass Conversion for Heat, Power, Fuels and Chemicals

No abstract provided.

Design Of A Lighter Than Air Vehicle That Achieves Positive Buoyancy In Air Using A Vacuum, Trent T. Metlen

Theses and Dissertations

Three designs for a Lighter Than Air (LTA) structure that achieve positive buoyancy using a vacuum in place of a lifting gas were proposed and evaluated. The ratio of structure weight to the weight of displaced air was termed Weight/Buoyant Force (W/B) where a W/B1 corresponds to positive buoyancy. Two methods of geometrically stiffening a sphere were investigated and their W/B evaluated. A thin shelled sphere of beryllium stiffened with an isogrid of blade type stiffeners using Ultra High Modulus (UHM) carbon epoxy was predicted to give a W/B= 0.79. A geodesic sphere composed of a frame of cylindrical, UHM, …

Kosmos : A Virtual 3-D Universe, John Judnich

Computer Science and Engineering Senior Theses

Kosmos is an application enabling interactive visualization of a fictional 3D universe. It offers users the opportunity to explore and experience an aesthetically pleasing virtual environment complete with billions of high-resolution planets and stars. Kosmos integrates several novel 3D rendering techniques in terrain rendering, large-scale particle systems, etc. to make this level of graphical realism and scale possible. The efficiency of the algorithms developed for this project enables average hardware (such as almost any modern laptop) to run Kosmos smoothly. Moreover, through the use of the recent WebGL standard, Kosmos may be viewed online in any modern web browser on …

Sustainability Issues Regarding Bamboo As A Renewable Feedstock For Fuels And Materials, Claudia Daza

BioEnergy IV: Innovations in Biomass Conversion for Heat, Power, Fuels and Chemicals

No abstract provided.

Quantum Coherence And Entanglement In The Avian Compass, James A. Pauls, Yiteng Zhang, Gennady P. Berman, Sabre Kais

Birck and NCN Publications

The radical-pair mechanism is one of two distinct mechanisms used to explain the navigation of birds in geomagnetic fields, however little research has been done to explore the role of quantum entanglement in this mechanism. In this paper we study the lifetime of radical-pair entanglement corresponding to the magnitude and direction of magnetic fields to show that the entanglement lasts long enough in birds to be used for navigation. We also find that the birds appear to not be able to orient themselves directly based on radical-pair entanglement due to a lack of orientation sensitivity of the entanglement in the …

Poly(N-Isopropylacrylamide)-Based Scaffolds For Tissue Engineering Applications, Pamela Kubinski

Theses and Dissertations

The primary goal of this work is to investigate the potential of poly(Nisopropylacrylamide)- based scaffolds in tissue engineering applications, specifically spinal injury and nucleus pulposus replacement. Poly(N-isopropylacrylamide), denoted PNIPAAm, is a synthetic polymer with hydrophilic properties at room temperature, but above 32C the chains become hydrophobic and entangle to form physical crosslinks. This thermoresponsive property enables PNIPAAm to be implanted as a free-flowing solution at room temperature and collapse into a gel in physiological conditions. However, as a homopolymer, the hydrophobicity of PNIPAAm in vivo causes the hydrogel to expel water and exhibit inelastic properties that do not mimic those …

Mylife, Lauren Furumoto, Will Truettner

Computer Science and Engineering Senior Theses

As we continue to utilize the web to manage organizations and institutions such as Santa Clara University Law School, we are challenged with the problem of keeping all of the different services in concise, cohesive interfaces. myLife attempts to consolidate currently scattered services relevant to SCU Law students and faculty into one dashboard for easy access and utilization. myLife requires only one set of credentials and displays the relevant mail, news, events, and course information for a given user on one userfriendly page.

Tools For Assessing Climate Impacts On Fish And Wildlife, Chad B. Wilsey, Joshua J. Lawler, Edwin P. Maurer, Donald Mckenzie, Patricia A. Townsend, Richard Gwozdz, James A. Freund, Keala Hagmann, Karen M. Hutten

Civil, Environmental and Sustainable Engineering

Climate change is already affecting many fish and wildlife populations. Managing these populations requires an understanding of the nature, magnitude, and distribution of current and future climate impacts. Scientists and managers have at their disposal a wide array of models for projecting climate impacts that can be used to build such an understanding. Here, we provide a broad overview of the types of models available for forecasting the effects of climate change on key processes that affect fish and wildlife habitat (hydrology, fire, and vegetation), as well as on individual species distributions and populations. We present a framework for how …

A Framework For Realistic 3d Tele-Immersion, P Fechteler, A Hilsmann, P Eisert, S V. Broeck, C Stevens, J Wall, M Sanna, Davide Andrea Mauro, F Kuijk, R Mekuria, P Cesar

Computer Sciences and Electrical Engineering Faculty Research

Meeting, socializing and conversing online with a group of people using teleconferencing systems is still quite different from the experience of meeting face to face. We are abruptly aware that we are online and that the people we are engaging with are not in close proximity. Analogous to how talking on the telephone does not replicate the experience of talking in person. Several causes for these differences have been identified and we propose inspiring and innovative solutions to these hurdles in attempt to provide a more realistic, believable and engaging online conversational experience. We present the distributed and scalable framework …

Fin Flutter Analysis, Richard Bauer, Austin Hardman

Aerospace Engineering

This report summarizes the experimental process executed to study fin flutter characteristics. The experiment analyzed the influence of the relationship between structural dynamics and aerodynamics on flutter characteristics. Theoretical models were created in PATRAN/NASTRAN and FinSim for comparison to experimental results and to set the envelope of the physical experiments. The theoretical analysis predicted the occurrence of flutter near Mach 1 or Mach 5. The physical model was constructed of solid aluminum with machined holes for the inertial sensors. Two test runs were completed to collect data on the displacement of the fin in the supersonic wind tunnel. Additionally, the …

Application Of Systems Engineering And Project Management For Algae Photo Bioreactors, Andrew S. Balberchak

Industrial and Manufacturing Engineering

EXECUTIVE SUMMARY

Today there is much talk about different sources for biofuel to replace the decreasing supply of fossil fuels. Algae seem very promising with its abundance across the globe and relatively simple growing conditions. Lipids can be extracted from this organism which is then converted to biofuel. Although biofuel production from algae is not economically viable at this stage, researchers are suggesting using the by-products of algae for supplemental and healthcare use. If true, this could justify the economics of obtaining fuel from algae by creating more markets from various algae products.

Cal Poly State University’s Food Science and …

Convertible High Heel Design, Mathew Caspari, Tyler Shelton

Industrial and Manufacturing Engineering

Many women feel pain and discomfort when wearing high heels to certain events. This is a problem because it can lead to a variety of health issues. It would be beneficial and convenient if a woman could remove the heelpiece from her shoe while still wearing the same product. However, there is currently no popular high heels that can convert to a flat shoe on the market today. Our goal was to perform an in depth human factors analysis with regards to high heel use and formulate a solution to these problems. After reviewing literature, conducting a survey, and analyzing …