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Cost-Effective Solutions For High-Throughput Enzymatic Dna Methylation Sequencing, Amy Longtin, Marina M. Watowich, Baptiste Sadoughi, Rachel M. Petersen, Sarah F. Brosnan, Kenneth Buetow, Qiuyin Cai, Cayo Biobank Research Unit, Vanderbilt University, Michael D. Gurven, James P. Higham, Heather M. Highland, Yi-Ting Huang, Hillard Kaplan, Thomas S. Kraft, Yvonne A. L. Lim, Jirong Long, Amanda D. Melin, Michael J. Montagne, Jamie Roberson, Kee Seong Ng, Michael L. Platt, India A. Schneider-Crease, Jonathan Stieglitz, Benjamin C. Trumble, Vivek Venkataraman, Ian J. Wallace, Jie Wu, Noah Snyder-Mackler, Angela Jones, Alexander G. Bick, Amanda J. Lea May 2025

Cost-Effective Solutions For High-Throughput Enzymatic Dna Methylation Sequencing, Amy Longtin, Marina M. Watowich, Baptiste Sadoughi, Rachel M. Petersen, Sarah F. Brosnan, Kenneth Buetow, Qiuyin Cai, Cayo Biobank Research Unit, Vanderbilt University, Michael D. Gurven, James P. Higham, Heather M. Highland, Yi-Ting Huang, Hillard Kaplan, Thomas S. Kraft, Yvonne A. L. Lim, Jirong Long, Amanda D. Melin, Michael J. Montagne, Jamie Roberson, Kee Seong Ng, Michael L. Platt, India A. Schneider-Crease, Jonathan Stieglitz, Benjamin C. Trumble, Vivek Venkataraman, Ian J. Wallace, Jie Wu, Noah Snyder-Mackler, Angela Jones, Alexander G. Bick, Amanda J. Lea

ESI Publications

Characterizing DNA methylation patterns is important for addressing key questions in evolutionary biology, development, geroscience, and medical genomics. While costs are decreasing, whole-genome DNA methylation profiling remains prohibitively expensive for most population-scale studies, creating a need for cost-effective, reduced representation approaches (i.e., assays that rely on microarrays, enzyme digests, or sequence capture to target a subset of the genome). Most common whole genome and reduced representation techniques rely on bisulfite conversion, which can damage DNA resulting in DNA loss and sequencing biases. Enzymatic methyl sequencing (EM-seq) was recently proposed to overcome these issues, but thorough benchmarking of EM-seq combined with …


Essays In Corporate Governance And Financial Intermediation, Renping Li May 2025

Essays In Corporate Governance And Financial Intermediation, Renping Li

Olin Business School Graduate Student Theses and Dissertations

Antitrust regulations in banking have historically targeted commercial banking activities. In the first chapter, I ask does the consolidation of investment banks have competitive effects? Using the geographically fragmented municipal bond underwriting market as a natural laboratory and employing a stacked difference-in-differences specification, I find that the underwriting spread increases by 4.8% of its sample mean following within-market consolidation. The effects double for larger M&As or in more concentrated markets and do not dissipate over time. These M&As do not generate efficiency gains that manifest as lower bond yields or substitution of other issuer-paid services. The findings remain robust when …


Essays In Empirical Asset Pricing, Jiaen Li May 2025

Essays In Empirical Asset Pricing, Jiaen Li

Olin Business School Graduate Student Theses and Dissertations

My dissertation explores two broad questions. First, what is the role of intangible forces like ideological narratives in belief formation and asset prices? Second, how can we understand the systematic components in asset pricing? In Chapter 1, using cryptocurrencies as a laboratory, I examine the role of ideological narratives in asset prices—an area remains underexplored. Leveraging social media data and large language models to measure ideology dynamics, I find that fluctuations in two ideological narratives—anarchism and decentralization—are priced in the cross-section of cryptocurrency returns. Consistent with the view that factors proxy for state variables, ideology factors contain distinct information about …


Explaining The Satisfaction Of The Religious Tourist: The Case Of Maimonides In The City Of Cordoba, César Mora Márquez, Angelo Puccia May 2025

Explaining The Satisfaction Of The Religious Tourist: The Case Of Maimonides In The City Of Cordoba, César Mora Márquez, Angelo Puccia

International Journal of Religious Tourism and Pilgrimage

Tourism was one of the most severely affected sectors by the Covid-19 pandemic. Even religious tourism, traditionally less susceptible to market fluctuations, is now compelled to adopt innovative strategies in response to these effects. This article analyses the satisfaction of religious tourism, specifically its relationship with the figure of Maimonides, who is considered to be an important religious thinker and is included within the Pantheon database of the Massachusetts Institute of Technology (MIT). A questionnaire was distributed and completed by 720 tourists in the city of Cordoba, Spain, which has close links to Maimonides. The findings indicated that the spirituality …


Intergenerational Mobility In Ottoman Istanbul: Evidence From Court Records, Metin M. Coşgel, José-Antonio Espín-Sánchez, Emre Özer May 2025

Intergenerational Mobility In Ottoman Istanbul: Evidence From Court Records, Metin M. Coşgel, José-Antonio Espín-Sánchez, Emre Özer

Discussion Papers

We use data from the Istanbul court registers spanning from the 16th -19th centuries to establish, for the first time, long-term trends in intergenerational mobility in a major premodern city. The dataset contains information on over 270,000 individuals who appeared in court in various roles, including litigants, witnesses, and representatives. Crucially, it records the honorific titles (if any) of individuals and their fathers, which we use as measures for socioeconomic status. Our goal is to trace long-term changes in Istanbul’s social structure, analyze the relationship between fathers’ and sons’ titles to assess shifts in intergenerational mobility, and determine whether these …


Tulsa Remote’S Benefits For Other Tulsa Residents: Results And Implications, Timothy J. Bartik May 2025

Tulsa Remote’S Benefits For Other Tulsa Residents: Results And Implications, Timothy J. Bartik

Presentations

No abstract provided.


The Effects Of Tulsa Remote On Inducing Moves To Tulsa: Estimates And Implications, Timothy J. Bartik May 2025

The Effects Of Tulsa Remote On Inducing Moves To Tulsa: Estimates And Implications, Timothy J. Bartik

Upjohn Institute Technical Reports

Tulsa Remote is one of the largest of over 100 remote worker attraction programs in the United States. Since its beginning in 2018, the program has provided generous incentives ($10,000 for moving to Tulsa and staying one year), along with accompanying networking services and incentives to encourage entrepreneurship, to over 3,000 Tulsa Remote member households, selected out of tens of thousands of applicants. Tulsa Remote’s purpose is to promote economic development in Tulsa. Tulsa Remote members spend more locally and generate fiscal benefits, as well as start up businesses and help make Tulsa more attractive for high-tech job growth. These …


Hospitality Operators And Cannabis Tourism In The South: Insights On Policy & Regulations, Nick E. Johnston, Kelly Way, Chloe Tyner, Betsy Garrison May 2025

Hospitality Operators And Cannabis Tourism In The South: Insights On Policy & Regulations, Nick E. Johnston, Kelly Way, Chloe Tyner, Betsy Garrison

ICHRIE Research Reports

Cannabis tourism offers new opportunities for U.S. hospitality, although regional adoption is limited and complex due to diverse legal frameworks. Through qualitative document analysis (QDA) of regulatory frameworks in 14 Southern U.S. states, this study compares policies on consumption, sales, and employment in states with limited or emerging cannabis programs. Findings reveal that hospitality operators can enhance guest experiences by creating private, wellness-focused cannabis environments and advocating for gradual policy adjustments. However, compliance with strict consumption, licensing, and workplace rules is essential to mitigate legal risks. This study highlights the South's cannabis tourism potential within politically conservative markets, suggesting that …


"Artificial Intelligence And Economic Development In Ghana: Assessing The Role Of Government Policy And Regulation", Sebastian Sharma May 2025

"Artificial Intelligence And Economic Development In Ghana: Assessing The Role Of Government Policy And Regulation", Sebastian Sharma

Senior Theses

Artificial intelligence (AI) is rapidly transforming economies worldwide, with profound implications for economic development in the Global South. Various questions arise regarding whether these changes will positively or negatively impact the economy and individuals worldwide. In this thesis, I examine how Ghana has implemented AI and utilized it to generate economic growth for all members of its society. I argue that through government regulation and framework Ghana was able to maximize the benefits AI has to offer while also minimizing the various risks it may bring. Ghana is a perfect example of how a country in the Global South despite …


Econometric Analysis Of Social Interactions And Decision-Making, Shuo Qi May 2025

Econometric Analysis Of Social Interactions And Decision-Making, Shuo Qi

Economics Theses and Dissertations

This dissertation explores the econometric analysis of social interactions and decision-making. The first two chapters advance econometric methodology by addressing key challenges in identifying and estimating peer effects, specifically tackling issues related to partial network data and endogenous link formation. The third chapter presents an empirical analysis of parental over-aspiration and its impact on children's academic outcomes, using monotone instrumental variables constructed from social network structures.

Chapter 1 is "Identification and Estimation of Discrete Choice Models with Spillovers Using Partial Network Data". This paper investigates peer effects in discrete choice models with incomplete data on social links. We consider an …


Who Owns The Wind: The Absence Of Community Wind Farms In California, Sky Berry-Weiss May 2025

Who Owns The Wind: The Absence Of Community Wind Farms In California, Sky Berry-Weiss

Master's Projects and Capstones

Community ownership structures for wind farms have been around for decades, particularly in European countries, due to high socioeconomic benefits. Given these significant benefits, one might expect community wind to thrive in the United States—especially in a state like California, which prides itself on progressive climate policy and renewable energy leadership. Yet utility-scale community wind remains largely absent from research on California’s energy system, raising questions about its existence in the state. To pinpoint how many utility-scale community owned wind farms are in California, this study surveys every operational wind turbine in the state. After classifying each wind farm by …


Loadshedding And Nighttime Light Intensity In South Africa: Evidence From High-Frequency Satellite Data, Jurney Lajos May 2025

Loadshedding And Nighttime Light Intensity In South Africa: Evidence From High-Frequency Satellite Data, Jurney Lajos

Master's Theses

This paper investigates the relationship between loadshedding and nighttime light intensity in South Africa using high-frequency satellite data from 2020 to 2024. By linking rotational blackout schedules to daily radiance measurements at the suburb level, the study examines how electricity disruptions affect visible light emissions and whether these effects vary by wealth. Results show that while load shedding has be-come increasingly severe in recent years, its impact is not felt equally. Poorer suburbs experience larger and more persistent reductions in nighttime radiance during black-outs, suggesting limited capacity to adapt. In contrast, wealthier suburbs show signs of resilience, with smaller drops …


Analyzing Immigrant Pay Gaps & The Policies That Influence Them, Rebeca Perez, Prachi Jain May 2025

Analyzing Immigrant Pay Gaps & The Policies That Influence Them, Rebeca Perez, Prachi Jain

Honors Thesis

Despite making up 14% of the US population, little research has been done on pay gaps for immigrants, the majority of whom are Latin American immigrants. I analyze the effect of immigration on immigrants’ wages, specifically looking at the effects of region of birth, citizenship, and state immigration policies. I find that even when compared to natives with similar education, Latin American immigrants earn significantly less. Furthermore, while noncitizens earn less than natives and naturalized citizens earn more overall, Latin Americans face a larger penalty for noncitizenship and lower returns to citizenship. Finally, while living in Sanctuary and Anti-Sanctuary States …


First Annual Advances In Business Education Conference 2025 Proceedings, Kelsey Metz, Joshua Ray May 2025

First Annual Advances In Business Education Conference 2025 Proceedings, Kelsey Metz, Joshua Ray

Advances in Business Education (ABE) Conference Proceedings

Conference Overview: The First Annual Advances in Business Education (ABE) Conference was held on May 16, 2025, at Lincoln Memorial University in Harrogate, Tennessee. Hosted by the LMU School of Business, the ABE Conference was established to promote teaching excellence through innovation and collaboration in business education. With a focus on fostering meaningful dialogue among educators, researchers, and students, the conference welcomed participants from across disciplines and institutions. The event was structured around three key tracks:

Pedagogy & Teaching Excellence: Showcasing innovative teaching methods and strategies for enhancing student learning and engagement.

Business Research: Presenting research focused on advancing knowledge …


Unequal Shocks: The Heterogeneous Impact Of Earthquakes, Claire Marie James May 2025

Unequal Shocks: The Heterogeneous Impact Of Earthquakes, Claire Marie James

Master's Theses

What effect does neighborhood wealth have on disaster outcomes and disaster induced migration? Using the 2023 Kahramanmaraş Earthquake in Southern Türkiye and Syria as a natural shock, I examine how the short term migration response to building damage and earthquake exposure differs by average neighborhood home prices. Using a panel dataset of population by bing tile, from Meta’s Data for Good Project, I employ time series and cross sectional regression analysis. I find that wealthy neighborhoods are better able to retain population than non-wealthy counterparts.


Downstream Delays: Effects Of Flooding On Childrens Education And Time Use In Peru, Miki Robert Izu May 2025

Downstream Delays: Effects Of Flooding On Childrens Education And Time Use In Peru, Miki Robert Izu

Master's Theses

Flooding is a major cause of destruction and economic loss affecting over 80 million people annually. Flooding during childhood can lead to educational setbacks with long term economic impacts. This study investigates the causal impacts of flood shocks on educational achievement and children's time use using the Young Lives Survey, a panel dataset surveying children in Peru over 19 years of childhood. This study finds that flooding causes a temporary positive "spike" in girls hours of labor immediately after a flood which subsides by three to six years after flooding. The additional hours of labor does not reduce hours of …


Climate Shocks, Crop Yields, And School Enrollment In Rural Ethiopia, Mallika Matharu May 2025

Climate Shocks, Crop Yields, And School Enrollment In Rural Ethiopia, Mallika Matharu

Master's Theses

This study investigates how climate-induced shocks to agricultural productivity affect school enrollment in rural Ethiopia. Using five waves of panel data from the Ethiopia Living Standards Measurement Study (LSMS) and satellite-derived weather indicators, I estimate the causal effects of crop yields, specifically Teff, Sorghum, and Maize, on children’s school attendance. To address the endogeneity of agricultural output, I instrument crop yields with agro-climatic measures such as growing degree days (GDD), harmful degree days (HDD), and soil moisture during the Meher growing season. The main empirical strategy uses a two-stage instrumental variable approach with region and wave fixed effects. Results suggest …


The Long-Term Effect Of Universities On Local Technology, Dafina Rizvanolli May 2025

The Long-Term Effect Of Universities On Local Technology, Dafina Rizvanolli

Master's Theses

This paper studies the long-term effects of universities on local economic complexity, contributing to new evidence on how higher education institutions shape local productive capabilities over time. While extensive research documents universities’ positive impact on development, fundamental questions remain about the mechanisms through which they operate. Our study employs the Economic Complexity Index (ECI), a measure that captures the diversity and ubiquity of regional economic structures, to provide novel insights into universities’ influence on local economies. Building on Andrews (2023), we exploit historical natural experiments in university site selection during the 19th and 20th centuries in the U.S. …


Effective Altruism, In-Group Favoritism, And Urban And Rural Values Across Cultures, Brian Chu May 2025

Effective Altruism, In-Group Favoritism, And Urban And Rural Values Across Cultures, Brian Chu

Master's Theses

Effective altruism has become an increasingly fashionable philosophy in recent years, with ardent supporters in Silicon Valley and other echelons of power. This study investigates to what extent people in urban and rural settings in the U.S., South Africa, and India act as effective altruists by employing an experiment in which participants must decide how to divide a $100 donation between two charities, one benefiting 10 people in their in-group and the other, more “effective” charity, benefiting 100 people in their out-group. The results show some areas in which U.S. urban populations act much more effectively altruistic than others, perhaps …


Two-Way Random Effects Model With Serial Correlation, Badi H. Baltagi, Georges Bresson, Jean-Michel Etienne May 2025

Two-Way Random Effects Model With Serial Correlation, Badi H. Baltagi, Georges Bresson, Jean-Michel Etienne

Center for Policy Research

This paper derives a feasible GLS estimator for a two-way error component model with serial correlation on both the time effects as well as the remainder disturbances. This estimator is based on two methods, one proposed by De Porres and Krishnakumar (2013) for deriving the spectral decomposition of a general error component structure and the other based on an inversion trick for the variance-covariance matrix of this model suggested by Skoglund and Karlsson (2001). While the last paper used maximum likelihood methods under the normality assumption, we use method of moments estimators following Baltagi and Li (1991) for the one-way …


The Hidden Logic Behind Migration And Success, Elsa Russom May 2025

The Hidden Logic Behind Migration And Success, Elsa Russom

Master's Projects and Capstones

This research paper explores the hidden drivers of financial success among Eritrean migrants navigating uncertainty, displacement, and limited institutional access. Drawing on original survey data collected from diaspora communities across East African host countries, I apply a mixed-methods framework combining ordinal and binary logistic regression, random forest classification, bootstrapping, and Bayesian causal mediation; to identify the structural and cultural variables most predictive of financial stability. The findings reveal that participation in Ekub, a traditional rotating savings association, and engagement in communal support systems are the strongest predictors of financial success, outperforming conventional factors such as age, education, or employment status. …


Entire Volume Journal Of Banking And Financial Economics 2025, 1(23) May 2025

Entire Volume Journal Of Banking And Financial Economics 2025, 1(23)

Journal of Banking and Financial Economics

Entire Volume Journal of Banking and Financial Economics 2025, 1(23)


Independent Vs. Signed Musicians: Does Thier Status Affect Their Success?, Zachary Vincent May 2025

Independent Vs. Signed Musicians: Does Thier Status Affect Their Success?, Zachary Vincent

Honors Projects in Mathematics and Economics

As technology has advanced and become more widely available, and as the public learns more about the recording industry and its workings, more musicians are choosing not to sign with record labels, becoming independent musicians. This now raises the question: does a musician’s status of independent or signed determine their level of success? It has been previously found that independent musicians have a more difficult time competing with signed musicians due to the resources provided by record labels and the way labels negotiate with large streaming platforms, giving signed labels more opportunities to be seen in the public eye, but …


Federal And State Governments Can Help Solve The Employment Problems Of People In Distressed Places To Spur Equitable Growth, Timothy J. Bartik May 2025

Federal And State Governments Can Help Solve The Employment Problems Of People In Distressed Places To Spur Equitable Growth, Timothy J. Bartik

Upjohn Institute Policy Papers

Places in the United States differ greatly in their residents’ access to jobs, especially good jobs. Although the federal and state governments provide about $80 billion annually to create jobs through multiple programs, these job-creation initiatives are rarely targeted to economically distressed places, where the job-creation benefits for local residents are greatest. Moreover, many of these programs take the form of business tax incentives, which are less effective at job creation than customized services for businesses and workers. I argue that the prime-age employment rate of places should be used to target job-creation programs and review which such programs are …


Federal Health Research Cuts In The Mountain West, 2025, Mia Tschan, Ivan Sun, Sydney Mitchell, Caitlin J. Saladino, William E. Brown Jr. May 2025

Federal Health Research Cuts In The Mountain West, 2025, Mia Tschan, Ivan Sun, Sydney Mitchell, Caitlin J. Saladino, William E. Brown Jr.

Health

This fact sheet presents data from the Science & Community Impacts Mapping Project (SCIMaP) report, “Impact of Federal Health Research Cuts,” which predicts economic and job losses resulting from proposed National Institutes of Health (NIH) funding/grants cuts for indirect research costs as of April 9, 2025. This fact sheet focuses on predicted economic and job loss for the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah, and county-level data for the State of Nevada.


Essays On Multinational Behavior, Brian Adam Green May 2025

Essays On Multinational Behavior, Brian Adam Green

Dissertations - ALL

This dissertation studies issues regarding the tax avoidance behavior of multinational corporations. It is composed of three chapters. The first examines the differential impact of the Tax Cuts and Jobs Act of 2017 on firm profit-shifting behavior. The second constructs a theoretical model in which the introduction of tax havens to a standard trade model leads to an oversupply of multinational exports and a decrease in public welfare. The third sheds light on multinational responses to the Great Recession of 2008. The US corporate income tax rate used to be the highest in the developed world, yet multinationals were able …


Accountability And Efficiency: Compiled Case Studies On Economic Development, Spending, And Global Markets, Jacob W. Grimsley May 2025

Accountability And Efficiency: Compiled Case Studies On Economic Development, Spending, And Global Markets, Jacob W. Grimsley

Honors Theses

This is a compilation of cases worked throughout the course of one year. These cases were created and assigned for an accountancy course focused on research and writing. The cases focus on accounting related topics, while also pertaining to political happenings as well as general economic topics.

Case 02 was completed in collaboration with other honors students, and these students are indicated on the page preceding this case.

Cases 05 and 06 pertain to a semester-long project focused on the development of a Mississippi based business. This case was also completed with the help of other students, as indicated on …


From Fraud To Future: Accountancy Case Studies On Financial Illusions, Policy Failures, And The Economic Renaissance Of Mississippi’S Broadband Initiative, Hayden Brennan Adams May 2025

From Fraud To Future: Accountancy Case Studies On Financial Illusions, Policy Failures, And The Economic Renaissance Of Mississippi’S Broadband Initiative, Hayden Brennan Adams

Honors Theses

This Honors Practicum is a compilation of case studies completed under the supervision of Dr. Victoria Dickenson across two semesters of the course Accountancy 420 — Independent Study. The first semester (Fall 2023) of case studies involved both individual and group case studies examining various geopolitical implications of contemporary accounting, as well as the surge in environmental, social, and governance (ESG) regulations affecting financial reporting. The second semester (Spring 2024) was mostly centered around a collaborative Mississippi economic development proposal project conducted by four other students and myself. In our project, we construct a business plan for a start-up broadband …


Asymmetric Recovery: Understanding The Differences In Commercial And Residential Recovery Patterns Following The 2008 Financial Crisis, Avery J. Flynn May 2025

Asymmetric Recovery: Understanding The Differences In Commercial And Residential Recovery Patterns Following The 2008 Financial Crisis, Avery J. Flynn

Honors Theses

The 2008 financial crisis revealed differences in economic recovery patterns between businesses and households. This study analyzes the asymmetry in loan delinquency rates between commercial and residential sectors, with data showing commercial rates peaked at 8.51% in 2010 while residential rates reached 10.88%, followed by significantly different recovery trajectories.

The research investigates how differing legal protections created varying incentives to cut costs. Through analyzing Federal Reserve data, Census Bureau surveys, and expenditure records, this study found the commercial sector recovered 64% within three years of its peak, compared to only 17% for the residential sector.

During the recession, businesses reduced …


Integrating Positive Psychology And Spirituality To Foster Meaning And Well-Being In Older Adults, Crystal Morris May 2025

Integrating Positive Psychology And Spirituality To Foster Meaning And Well-Being In Older Adults, Crystal Morris

Adultspan Journal

This perspective article explores the integration of positive psychology interventions (PPIs) and spirituality in therapy to foster meaning and well-being in older adults. It highlights exercises such as the positive introduction, positive legacy, character strengths, mindfulness, mindful-based yoga, and a manifestation prayer journaling. The interventions presented are tools to support older adults that may experience depression, difficult life transitions, and the search for renewed meaning. Therapists who integrate PPIs and spirituality into therapy can promote a holistic, non-pathological approach to treatment.