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Effect Of Time And Diet On The Immune Status Of Mice Challenged With Herpes-Transformed Cells, Daila S. Gridley

Loma Linda University Electronic Theses, Dissertations & Projects

Human Herpes simplex virus type 2 (HSV 2)-transformed Balb/c mouse cells (H238 cells) are malignant in Balb/c mice. The immune stratus of mice bearing H238 cell-induced tumors was studied and changes in immune response with time and with altered diet of the mice were measured.

In the experiments dealing with the status of immunity with time after tumor cell injection, mice were fed Purina Laboratory Chow (P.L.C.), injected with H238 cells, and sacrificed three to eight weeks post-injection. In the diet experiments, groups of mice were fed either P.L.C. or one of six equicaloric diets, consisting of low or high …

The Wavelength Dependence Of Ultraviolet Enhanced Reactivation In A Mammalian Cell-Virus System, Leslie C. James

Masters Theses & Specialist Projects

The effect of ultraviolet (UV) radiation in the wavelength region 230 nm to 302 nm on the ability of an irradiated mammalian cell to reactivate UV-irradiated mammalian virus was tests. An action spectrum for radiation enhanced reactivation (RER) Is presented. The shape of the action spectrum points to a combined nucleic acid protein target for UV radiation effects on this cellular parameter. An analysis of the results of others involving the biochemical and photobiological events involved in the RER does not allow the identification of the macromolecule which is the major contributor to this effect. Studies involving an analogous phenomenon …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1856-1975) T901-T1000, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T901. TRANSLATION FROM RUSSIAN. STARKOV, O. A. (1975). Anomalohimalaya lama Hoogstraal, Kaiser and Mitchell, a new ixodid tick genus and species for the fauna of USSR. Zool. Zh., 54(2):304-305.

T902. TRANSLATION FROM RUSSIAN. MOTEYUMAS, L. E. and EZERSKENE, E. P. (1974). Small mammals of human disease natural foci in Lithuanian SSR. Zool. Zh., 53(1):1580-1583.

T903. TRANSLATION FROM RUSSIAN. BELYAEVA, A. P. (1965). Omsk hemorrhagic fever virus culture in chick embryos. In: Endemic viral infections (hemorrhagic fever with renal syndrome, Crimean hemorrhagic fever, Omsk hemorrhagic fever, and Astrakhan virus from Hyalomma pl. plumbeum tick), ed. Chumakov, M. P. Trudy Inst. Polio. …

The Great Potato Debate, James D. Hudson

Honors Theses

Anencephaly and spina bifida cystica are two of the most common severe congenital malformations consistently observed in human populations. Both represent defects in the neural tube and share a significant number of similar epidemiological associations among them, occupational class, geography, sex ratio, maternal age, year and season of the year. In anencephaly most of the brain and upper skull never form usually resulting in death within a few hours of birth. Spina bifida cystica is a malformation of the spinal cord often causing paralysis, vulnerability to infection, and early death. In 1972, Dr. J.H. Renwick presented a controversial hypothesis which …

Comparison Of Interferon Produced In Vitro By Monkey Kidney Cells Demonstrating Interference Against Polio Ii, Coxsackie A-9, Influenza A2/Hong Kong/68, And Echo-9 Viruses, Archer Duncan Farmer Jr.

Biological Sciences Theses & Dissertations

Abstract unavailable

Studies On The Regulation Of Cell Growth And Contact Inhibition Using Concanavalin A And Dibutyryl Adenosine Cyclic Monophosphate, Robert W. Teel

Loma Linda University Electronic Theses, Dissertations & Projects

Both dibutyryl cyclic AMP and trypsinized concanavalin A have been shown to inhibit growth in certain cell lines but little testing of these substances has been done using human tumor cell lines. Further, there are at this time no published experimental attempts to correlate the effects on growth with a particular phase of the cell cycle in any cell line.

My experimental data show that the human tumor cell lines HeLa, HEp 2 and KB exhibit pronounced inhibition of growth when treated with trypsinized concanavalin A and reach a contact-inhibited state at a density far below that to which these …

A Study Of Precipitin And Soluble Antigen Fluorescent Antibody Technique In The Detection Of Dirofilaria Immitis In Canines, John H. Ellsworth

Biological Sciences Theses & Dissertations

Abstract unavailable.

Bibliography Of Diseases And Parasites Of Marine Fish And Shellfish (With Emphasis On Commercially Important Species), Carl J. Sindermann

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The literature on diseases and parasites of marine animals has been accumulating at an accelerating rate in recent decades, and at a seemingly geometrical rate in the past few years. Reviews of selected aspects of the subject have appeared (Cheng, 1967; Sindermann, 1966; Sindermann and Rosenfield, 1967). References listed in these papers include a significant, but still a small part, of the available literature. With the proliferation of journals in many languages throughout the world, a complete bibliography, even in a narrow area of research, is almost an impossibility. Then too, the daily appearance of new published information represents an …

This Could Happen Here : If Foot-And-Mouth Disease Came To Western Australia, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

THE first outbreak would probably be on a piggery not far from a major port. But it might also appear among cattle or sheep in a similar area, or even on a cattle station in the North.

Mastitis In Western Australian Dairy Cattle, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

IN 1964/65, as a first step towards a State-wide mastitis control programme, the Department of Agriculture undertook a survey of mastitis in West Australian dairy herds.

The survey was designed to obtain a clear picture of the incidence and severity of the disease and is the most comprehensive mastitis survey carried out in Australia.

A Brief History Of The Namru-3 Medical Zoology Program, Harry Hoogstraal

United States Naval Medical Research Unit 3: Publications

The NAMRU-3 Medical Zoology program began during Easter week of 1950. We had just closed the NAMRU-3 field station at Torit, in Equatoria Province of soulheastern Sudan, and were heading homeward to the United States. However, the offer to remain in Egypt for a year or two to develop a Medical Zoology department at NAMRU-3 provided an interesting challenge after working for several years in tropical forests and grasslands of Africa and other continents. We shall briefly describe subsequent events under four headings: (1) Medical Zoology in Egypt, (2) Ticks and Tickborne Diseases of the World, (3) Kala Azar in …

Carbon Dioxide Fixation In Schistosoma Mansoni, Clint Earl Carter

Loma Linda University Electronic Theses, Dissertations & Projects

Adults of the blood fluke Schistosoma mansoni were perfused from the hepatic portal system of CF1 female mice sixty to seventy days post infection. The worms were then incubated in Eagle’s minimal essential medium with glutamate and 0.03 mg/100 ml of nonlabelled aspartic acid. To this medium was added 10 μc of either NaH¹⁴0₃, glucose-UC¹⁴ or aspartate-4-C¹⁴. The worms were found to fix carbon from the NaH¹⁴0₃ and to incorporate the glucose and aspartate. The amount of activity recovered in five different chemical fractions after two hours incubation was determined …

Arthropods Of Medical Importance In Asia (And The European Ussr), Part Ii: Data On Arthropods Other Than Mosquitoes, Bernard V. Travis, Renato M. Labadan

Harold W. Manter Laboratory of Parasitology: Library Materials

Includes information on black flies, sand flies, midges, horse flies, biting flies, non-biting flies, fleas, bugs, urticating and vesicating arthropods, ticks, mites, and miscellaneous arthropods of medical importance from Asia and the European USSR.

Danger : Watch Out For Foot-And-Mouth Disease, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

This article was prepared by officers of the Department of Agriculture's Animal Division, with the approval of the Chief Quarantine Officer (Animals) for Western Australia.

THE introduction of foot-and-mouth disease into Australia would be an event of national importance.

Its economic consequences could be far-reaching and grave.

Ixodid Ticks: Possible Vectors Of Tuberculosis, Ya. A. Blagodarnyy, I. N. Blekhman, M. P. Yukunin

United States Navy: Publications

"From these tests, we established that artificially and naturally fed ticks are susceptible to the infective source and preserve tuberculosis mycobacteria in the body for a long period."

Review Of Echinococcus Species In South Africa, Anna Johanna Maria Verster

Harold W. Manter Laboratory of Parasitology: Faculty Publications

1. The nominate subspecies of E. granulosus (Batsch, 1786) is redesignated from the type locality, Europe.

2. Five subspecies of E. granulosus are described from South African carnivores: E. g. granulosus, E. g. africanus, E. g. felidis, E. g. lycaontis and E. g. ortleppi.

3. E. g. granulosus has so far only been recovered from the Transvaal; E. g. ortleppi appears to be restricted to the Transvaal; E. g. africanus occurs in the Orange Free State and the Transvaal; E. g. lycaontis and E. g. felidis like their definitive hosts are restricted to the Transvaal.

4. …

Index Catalogue To Russian, Central And Eastern European, And Chinese Literature In Medical Entomology, Volume 1: Diptera, George Anastes

United States Naval Medical Research Unit 3: Publications

Over the past several years a large number of references from the USSR, Eastern Europe, and China have been collected dealing with arthropods of medical importance. These references were coded on keysort cards which made it possible to index as many as fifteen subject areas on one card. The usefulness of this indexing system was evident by the number of medical entomologists who used it in searching for references in their specialty. In response to requests from workers in the United States and other countries who did not have ready access to the index. it was decided to publish these …

The Pathogenesis Of Periodontal Disease And Treatment Implications, Richard C. Oliver

Loma Linda University Electronic Theses, Dissertations & Projects

Presently accepted concepts of the etiology and pathogenesis of periodontal disease do not adequately explain the following consistent clinical observations: (1) equal local etiologic factors do not result in equal periodontal destruction in all patients; and, (2) equal therapy is not equally successful in all patients. The differences in patient response must be due to differences within the patient. By relating the broadened concept of disease, as described by Engel, to periodontal disease, the reasons for these individual patient differences become apparent. This concept consideres[sic] disease in relation to the patient's genie and developmental background, as well as the present …

Control Of Lice On Cattle, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

THE external parasites, biting and sucking lice (particularly of calves) are the cause of much unthriftiness.

Sarcoptic Mange Of Pigs, H D. Seddon, F. C. Wilkinson

Journal of the Department of Agriculture, Western Australia, Series 4

THIS parasitic disease appears to be much more common than is usually recognised; for, while severe cases with chronic skin lesions are readily seen, light infestations, especially on coloured pigs often go unnoticed.

When it is realised that even lightly infested pigs require twice as much feed to make one pound gain in live weight as do uninfested pigs, then early recognition and treatment of the disease becomes an obvious economical necessity.

Brucellosis Can Cause Contagious Abortion In Cattle And Undulant Fever In Man, F C. Wilkinson

Journal of the Department of Agriculture, Western Australia, Series 4

WHEN the cow, shown in the accompanying photograph, was purchased it had a small fluid-filled lump on the left knee.

The swelling did not appear to be painful but gradually increased in size until it assumed the proportions shown in the picture.

It was a typical case of "big-knee," one of the less common manifestations of Brucellosis—the disease commonly known as contagious abortion—and a blood test of the animal confirmed the diagnosis.

Copper And Cobalt Deficiency Of Livestock In Western Australia, H. W. Bennetts

Journal of the Department of Agriculture, Western Australia, Series 3

Part 1. Distribution and effects

DISEASES of animals due to copper and cobalt deficiencies are well known in this State where much of the original work, on the cause of these conditions, was carried out. These investigations have been recorded elsewhere and described briefly in this Journal by Filmer and Underwood (1936), Bennetts (1935), (1937), (1940), (1941), (1942) and Bennetts et. al. (1939), (1942). During more recent years the distribution of these deficiencies in Western Australia has been surveyed in some detail. This survey has been made by field investigations and by chemical estimations of animal tissues and pastures from …

Natural History Of Thelazia Californiensis Price, 1930 (Nematoda: Thelaziidae), A Mammalian Eye Worm, Warren E. Parmelee

Loma Linda University Electronic Theses, Dissertations & Projects

Various factors—embryology, host associations, and seasonal changes In eye worn populations—tending to promote the propagation of T. califomlensls were studied.

The early embryology closely parallels that of other nematode species.

The mature embryos remain alive in saline at 35°C as long as 5 days. Dead embryos can be distinguished from living ones by virtue of the rapid staining by methylene blue by the former. Parturient female thelazias release embryos into saline, and embryos are found regularly in tear secretions of infected laboratory rabbits.

Ovic embryos possess an enveloping egg membrane containing chitin. On this account, this eye worm species is …

Natural And Experimental Infections Of Thelazia Californiensis Price (1930, Nematoda: Thelaziidae) With Descriptions Of The Adult And Larval Parasites, Howard S. Burnett

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this work was to determine the extent and effects of infestation of the eye worm of mammals, Thelazia californiensis, and to elucidate through experimentation or observation the mode of transmission.

A survey of literature revealed that thelaziasie (infestation by Thelazia species) may cause serious pathological changes in the eye and its adnexa, sometimes resulting in blindness. It was found that reports of thelaziasis in the United States were (with two exceptions) of cases in California. It was further found that T. californiensis has been reported in a wider variety of host than has any of other …

Case Of Collecting Tick Amblyomma Lepidum Dönitz, 1909, In Azerbaijan, M. V. Pospelova-Shtrom, N. S. Abusalimov

United States Naval Medical Research Unit 3: Publications

First paragraph:

On 18 May 1954, (a specimen of) Burhinus oedicnemus (L.) was killed in the Lenkoransky region of Azerbaijan S.S.R.; on its head a male Amblyomma lepidum Dönitz, 1909, was found. Morphological characters of this tick, size and shape of body, characteristic light and dark ornamentation of dorsal shield, punctation, shape, and two colors of festoons, size and shape of cervical and lateral grooves, hypostome, peritreme, projection on coxae, and spherical orbited eyes correspond to those in the description of A. lepidum, given in Robinson monograph. Only on four anterior festoons a small light spot is found (in …

Key To The Genus Ornithodorus (Of Russia) (After Pavlovsky, 1955), I. G. Galuzo

United States Naval Medical Research Unit 3: Publications

English translation from Russian of pp. 83-85 of Galuzo (1957) Argasid ticks and their epizootological significance. Alma-Ata (Acad. Sci. Kazakh SSR).

Females and Males

Ornithodoros papillipes (Birula, 1895)

O. verrucosus (Sas, Fen. 1934)

O. tartakovskyi (Olenev, 1931)

O. nereensis (Pavlovsky, 1941)

O. alactagalis (Issaakjan, 1936)

O. canestrini (Birula, 1895)

O. lahorensis (Neumann, 1908)

Ixodid Ticks Of Ussr Fauna [Excerpt], G. V. Serdyukova

United States Naval Medical Research Unit 3: Publications

Key to Hyalomma

Males

Females

(Summary) Of Variation In Pasture Ticks (Acarina, Ixodidae) And Its Significance For Systematics, G. S. Pervomaisky

United States Naval Medical Research Unit 3: Publications

First paragraph:

1) Pasture ticks (Ixodidae) have a great significance as specific vectors and stimulators of many infectious diseases of man and cattle.

Subacute Enterococcal Endocarditis Following Epidemic Hemorrhagic Fever, Thomas N. James, Edward L. Quinn

Henry Ford Hospital Medical Journal

No abstract provided.

Experiments In Transmission Of Theileriasis And Anaplasmosis Of Sheep Through Ticks Ornithodoros Lahorensis And Haemaphysalis Sulcata, P. A. Bitukov

United States Naval Medical Research Unit 3: Publications

First paragraph:

In conducting inspection of sheep on haemosporidiosis in some districts of South-Kazakhstankoi region, we repeatedly observed theileriasis and anaplasmosis of sheep.

Note: Numerous other experimental data in this paper are omitted from the present translation. This report is of special interest because it establishes the role of an argasid tick as a vector of blood protozoa. Translation made and distributed by Medical Zoology Department, U. S. Naval Medical Research Unit no. 3, Cairo, Egypt.