Digital Commons Network^™

Spontaneous Superior And Inferior Pancreaticouduodenal Artery Pseudoaneurysms In The Setting Of A Retoroperitoneal Hematoma Surrounding The Pancreatic Head, Asad Rehman, Jordan Torres, Salman Islam, Bushra Bangash, Lakshmi Tatineni, Aneesha Shaju

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Colon Adenocarcinoma Mimicking Acute Appendicitis In A 28-Year-Old, Bridget Kowalczyk, Edward Pingenot, Vivek Bansal

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Screen It Out! Improving Colon Cancer Screening Among Kingwood Clinic Patients, Daniel J. Avila Castillo, Bhavin Patel, Dhruv Patel, Rajeev Raghavan, Zuhair Ali

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Artificial Intelligence Response To Common Medication Concerns With Heart Failure Gdmt In Outpatient Setting, Dominique Pean, Laaraeb Nadeem, Suhas Kandimalla, Brotee Rahman

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Obstructive Esophageal Mass In A 40-Year Old Female Presenting As Intractable Vomiting And Early Dka: A Case Report, Caroline Andrews, Rachel Hogan

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

A Case To Cause Pause, Kai Tubb, Stevley Koshy

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Arteriovenous Fistula Communicating With Venous Stent In Aptient With Arterial Aneurysm, Timot Kellermayer, Renley Summay, Bryan Kharbanda

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Intracrnial Hemorrhage And Ecg Changes, Negar Niknam, Eric N. Riha, Bushra Bangash, Parshvi Patel, Skantha K. Manjunath, Gnananandh Jayaraman, Ramesh Kesavan, Siva T. Sarva

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Clinical Impact Of Indeterminate Quantiferon-Tb Test Results For A Patient With Recurrent Inflammatory Bowel Disease Flares, Asad Rehman, Bushra Bangash, Aashka Patel, Anam Zara, Hong Thai, Ismail Hader

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Unusual Delayed Invasive Infection With Staphylococcus Capitis Following Coronary Artery Bypass Grafting: A Case Report And Literature Review, Suhas Tatapudi, Daniel J. Avila Castillo, Ibrahim Yazji

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Persistent Poverty And Incidence-Based Melanoma Mortality, Tiffaney Tran, Karla Madrigal, Lillian Morris, Kehe Zhang, Emelie Nelson, Marcita Galindez, Zhigang Duan, Adewole S. Adamson, Hui Zhao, Hung Q. Doan, Madison M. Taylor, Cici Bauer, Kelly C. Nelson

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

An Eluding Case Of Glomerulonephritis Found To Be Fibrillary In Nature, Julien Ogilvie, Amanda Tchakarov

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

A Rare Case Of Infected Bronchogenic Cyst Growing Salmonella Enterica, Diane S. Habib, Jordan Torres, Salman Alim

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

A Case Of Heyde Syndrome: Management And Anti-Coagulation, Muhammad Siddiqi, Hamza Naveed, Ashley Charales, Marloe Prince Jr.

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Surgical Management Of Massive Localized Lymphedema: A Case Report, Joseph Daodu, Alexys Ramos, Rainna Coelho, Natalia Cavagnaro, Mike Liang

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Understanding Hypomagnesemia In Patients With Short Bowel Syndrome, Aashka Patel, Sakina Haider, Thomas Hoang, Rajeev Raghavan

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Case Of Bilateral Glaucoma, Raj Patel, Hengameh Pajer, Rasheed Lawal

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Novel Engineering Approaches For Orthopedic Injury Treatment And Infection Diagnosis, Cynthia Co

Bioengineering Dissertations - Archive

Bioengineering has made significant contributions to the treatment of orthopedic injury through interdisciplinary approaches. Central to these advancements are many orthopedic implants, including anchors and joint replacements, which have been designed to restore mobility. Despite their functional efficacy, these products have limited lifespan and are associated with many complications, such as implant-associated infection. The success of implant design and function, both in the short and long term, is paramount for enhancing patient outcomes and overall well-being. Therefore, my thesis work is dedicated to addressing these critical challenges, aiming to maximize their treatment effect while minimizing the implant-associated complications.

Long-term patient …

Improving Patient Self-Advocacy And Communication With Providers Through Diabetes Self-Management Education: Analyses From A Randomized Controlled Trial, Brenna Owens Kirk

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: West Virginia (WV), a rural state in Appalachia, has the highest type 2 diabetes mellitus (T2DM) prevalence in the United States. Open communication in the patient-provider relationship is an integral part of comprehensive chronic disease management. This is especially true for patients living with T2DM, a disease that requires many complex, daily self-management activities and is associated with increased emotional distress. However, patients living with T2DM are often reluctant to openly share their concerns regarding self-care with their provider. This study aimed to test the effectiveness of the Diabetes and Hypertension Self-Management Program (DHSMP), a 12-week group lifestyle …

Impact Of The Use Of Nutrition Information On Glycemic Control In Adults With Diabetes, Katelyn Richardson

All Master's Theses

The purpose of this study is to examine the association between glycemic control in adults with diabetes and the use of nutrition information (NI). A cross-sectional design evaluated adults with diabetes from the 2009-2010 and 2017-2020 NHANES databases. Use of NI was quantified based on the subject’s use of the Nutrition Facts Label, use of calorie information at restaurants, and use of either the USDA Food Guide Pyramid or My Plate. Glycemic control was established if the subject’s hemoglobin A1C concentration was 7.0% or lower. SAS Software (v. 9.4) was used for all statistical analysis. Differences between prevalences were established …

Prenatal Androgen Exposure Reduces Ovarian Function, Marlee Weets

All Master's Theses

Polycystic ovary syndrome (PCOS) is the most common reproductive and endocrine disorder, being the leading cause of infertility for females of reproductive age. The etiology of PCOS is not fully known, although it is hypothesized that there is a genetic, epigenetic, and environmental component to the disease. One of the environmental influences that can cause an abnormal reproductive phenotype similar to PCOS is prenatal exposure to excess androgens (male sex hormones). Previous studies have shown that prenatal exposure to androgens in mice can cause a PCOS-like ovarian phenotype similar to people with PCOS. To examine how prenatal androgen exposure causes …

Relationship Between Thyroid-Stimulating Hormone (Tsh) Levels And The Presence Of Non-Alcoholic Fatty Liver Disease (Nafld) Among Asymptomatic Individuals, Mohamed Ramzy Alawy, Shimaa M W Kalama, Rania T H Gebba, Samah Mohammed Abdelmonem Abu Sholaa, Asmaa M Soliman

Journal of Medicine in Scientific Research

Background: Thyroid gland and its hormones have a crucial effect in body weight regulation, metabolism of lipid, and insulin sensitivity, which all of them play an important and significant effect in the process of non-alcoholic fatty liver disease (NAFLD) development. Aim: This study aimed to evaluate the potential risk of occurrence of metabolic syndrome in euthyroid persons with NAFLD . Subjects and Methods: - This cross-sectional study was carried out on outpatient cases in the Department of Internal Medicine at Shebin El-Kom Teaching Hospital. Conducted between February 2024 and August 2024, our study included 96 participants recruited from outpatient clinic. …

Serum Procalcitonin As An Early Marker Of Diabetic Foot Sepsis In Shebin Elkom Teaching Hospital, Asmaa M Soliman, Shimaa M W Kalama, Rania T H Gebba, Randa I. Ahmed Elshiha, Samah Mohammed Abdelmonem Abu Sholaa, Elham T Awwad, Mohamed Ramzy Alawy, Mohamed Abdel Samie Abdelkhalek Elbahat

Journal of Medicine in Scientific Research

Background Diabetic foot infections are a serious consequence of diabetes mellitus, frequently resulting in major health problems such as amputation. Traditional diagnostic markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) have limitations, spurring more research into procalcitonin (PCT) as a possibly more reliable predictor of infection severity and consequences. Objectives To compare the efficacy of (PCT) to standard inflammatory indicators (ESR and CRP) in predicting outcomes of acute diabetic foot infections (DFI) and to determine its potential benefits in clinical settings. Patient and Methods A cross-sectional study was undertaken at Shebin Elkom Teaching Hospital between December 2023 …

Early Outcome Of Mini-Mvs Surger Y Elsherif Et Al., Mahmoud Abdullghany Amin Elsherif, Rasha Hosny, Mohamed Ramadan Mohamed

Journal of Medicine in Scientific Research

Background: The conventional incision adopted to for mitral valve replacement is the full sternotomy, with proved over time and experience to be a simple and safe method. Minimal invasive mitral valve surgery (Mini-MVS) is an alternative approach for elective mitral surgeries that proved over the last years to be a promising option.

Aim of the study: Assessment of the early outcome of minimally invasive mitral valve surgery with or without tricuspid surgery.

Methods: A retrospective study on 100 consecutive patients who underwent minimal invasive mitral valve surgery from January 2021 to June 2023 at National Heart Institute in Egypt.

Results: …

A Review On The Genetic Backgrounds And Management Behind Common Podiatric Disorders, Corinne Niedermier

Williams Honors College, Honors Research Projects

I am writing a review paper on multiple diseases treated by podiatrists (diabetic foot ulcers), gout, neuropathy, and Charcot feet). The paper will focus heavily on the genetic causes of the disease, how they occur, and the treatment.

Molecular Determinants Of Trp Channel Gating, Briar J. Bell

Theses and Dissertations (ETD)

Transient Receptor Potential (TRP) ion channels are a family of proteins that contribute to a myriad of physiological functions. They have been extensively studied since their discovery 35 years ago; however, there are still many questions regarding the mechanisms by which they function. This family of proteins is characterized by a generally shared structure: an intracellular N terminus featuring ankyrin repeats, six transmembrane helices including the pore domain, a re-entrant loop and TRP helix, and an intracellular C terminus with varying structure. Each of these regions has been implicated in the regular function of TRPs, while mutations that alter trafficking …

Characterizing The Cellular Response To Astrovirus Infection In The Central Nervous System, Amy E. Davis

Theses and Dissertations (ETD)

Central nervous system (CNS) diseases caused by infectious agents pose significant health challenges, often leading to severe neurological dysfunction with high morbidity and mortality rates. Astroviruses (AstVs), traditionally known for causing gastroenteritis, have recently been identified as neuroinvasive pathogens capable of inducing neurological diseases. This study explores the cellular and molecular mechanisms by which AstV, specifically non-classical VA1 and classical HAstV1 genotypes, induce CNS pathology in human neurons and astrocytes. Utilizing primary human neurons and astrocytes from various brain regions, this research investigates the cytotoxic effects, apoptotic pathways, and inflammatory responses triggered by these viruses. This study reveals that VA1 …

Pan-Cancer Genomic Characterization Of Human Papillomavirus Associated Tumors, Jeremiah Ray Holt

Theses and Dissertations (ETD)

Infection with high-risk human papillomavirus (HPV) accounts for nearly all cervical cancers (CESC), a subset of other anogenital squamous cancers, and increasing rates of head and neck squamous cell carcinomas (HNSC), with each cancer type having heterogenous outcomes due to a general lack of personalized care. Large scale genomic analyses have catalogued the somatic alterations occurring frequently among squamous tumor types including HNSC and CESC, but few studies have incorporated a thorough analysis of HPV genomics. High-risk HPVs are double-stranded DNA (dsDNA) viruses capable of integrating their genomes into host chromosomes, a phenomenon known to promote HPV-associated cancer formation. HPV …

Advancing Clinical Bacterial Diagnosis: Gram-Stained Whole-Slide Image Classification With Attention-Based Deep Learning, Jack Mcmahon

Computer Science Senior Theses

We introduce a new method for the classification of Gram-stained WSIs. As a test for the diagnosis of blood infections, Gram stains are highly relevant to informing patient treatment. Rapid analysis of Gram stains has been shown to be positively associated with better clinical outcomes, indicating the need for better tools to aid in automatic Gram stain analysis. To date, this area of research has been underexplored, with previous studies relying on the manual patch-level annotation of WSIs to generate training data. This is the first application of a transformer-based model to Gram-stain WSI classification, an approach that is far …

Role Of Human Intermediate Form Prl Receptor I-Tail In The Pathogenesis Of Breast Cancer, Shanwei Shen

Theses and Dissertations

Breast cancer continues to be the second most common cancer in women in the United States. The neuroendocrine hormone human prolactin (hPRL) plays an important role in normal mammary gland development and growth, stimulating normal breast tissue proliferation and differentiation. Considerable evidence has shown that hPRL is involved in the malignant transformation of human breast tissue. hPRL enhances viability, invasiveness, and proliferation of breast cancer cells in vitro. Evidence from epidemiologic and genetic studies also implicates role of hPRL in the pathogenesis of breast cancer. Its cognate receptor the human prolactin receptor (hPRLr) is required for the action of hPRL. …