Digital Commons Network^™

Reverse Engineering Of Binary Programs Using Graph Attention Networks, Sai Nikhila Kanigiri

Master's Theses

Understanding the functionality and behavior of binary code is essential for many software engineering tasks, including malware analysis, vulnerability detection, and program optimization. However, automating this process is challenging due to the complexity of machine code and the significant manual effort required from experienced software engineers. In this paper, we present BinGAT (Reverse Engineering of Binary Programs using Graph Attention Networks), a method for classifying binary programs into algorithmic categories using Graph Attention Neural Networks (GNNs) based on their Control-Flow Graphs (CFGs). Given a binary program, BinGAT extracts its CFG through static analysis and transforms the assembly instructions within each …

Computational Design Of Potent Sirna For Braf Oncogene Silencing For Enhancing Cancer Therapy, Muhammad Hermawan Widyananda, Ricadonna Raissa

Karbala International Journal of Modern Science

The discovery of oncogenic BRAF mutations has prompted the development of inhibitors, yet resistance remains widespread. A more effective strategy involves targeting BRAF mRNA with siRNA to overcome resistance to BRAF inhibitors. This study aims to design potent siRNA for BRAF oncogene silencing using a computational approach. The full coding sequence of BRAF was retrieved from the NCBI database and potential siRNAs were predicted using the Ui-Tei, Reynolds, and Amarzguioui rules. Identified siRNAs were further analyzed using various prediction systems and parameters, including their interaction with the hAgo2 protein. The results identified that seven siRNAs (siRNA 23, siRNA 24, siRNA …

Praxly: An Online Ide For The Praxis Cs Test Pseudocode, Benjamin Saupp

James Madison Undergraduate Research Journal (JMURJ)

No abstract provided.

Optimizing Information Security In Cloud Environments: A Risk Management Approach And Guide For Enterprise Cloud Security, Joshua Olusegun Oyeniyi, Oluwashina Akinloye Oyeniran

Journal of Cybersecurity Education, Research and Practice

In recent years, cloud computing has become increasingly integral to organizational operations due to its scalability, accessibility and cost effectiveness in managing data and resources. However, the rise in security threats and attacks on cloud environments necessitates having robust measures in place to protect data confidentiality, integrity and availability. This paper presents an optimized approach to cloud information security management by reviewing the current threat landscape, evaluating key risk management frameworks, and provided practical solutions for enhancing enterprise cloud security. The study examined three leading cloud security frameworks: the Cloud Controls Matrix (CCM) known for its cloud-specific controls, the NIST …

Weak Formulation For Solving Inverse Problems In Reproducing Kernel Hilbert Spaces (With Applications To Learning Dynamical Systems), Victor William Rielly

Dissertations and Theses

We combine numerical and machine learning techniques to present a general framework for solving inverse problems using vector valued reproducing kernel Hilbert spaces in a variational formulation. We present this framework in two papers. In the first paper, we present an original state-of-the-art method derived in the context of our general framework for learning dynamical systems. In the second paper, we generalize the method from our first paper to arrive at the framework for solving inverse problems. Then we apply our general framework to the task of learning dynamical systems. In both papers we consider numerous applications of our methods …

Improving The Reproducibility Of Deep Learning Software: An Initial Investigation Through A Case Study Analysis, Nikita Ravi, Abhinav Goel, James C. Davis, George K. Thiruvathukal

Computer Science: Faculty Publications and Other Works

The field of deep learning has witnessed significant breakthroughs, spanning various applications, and fundamentally transforming current software capabilities. However, alongside these advancements, there have been increasing concerns about reproducing the results of these deep learning methods. This is significant because reproducibility is the foundation of reliability and validity in software development, particularly in the rapidly evolving domain of deep learning. The difficulty of reproducibility may arise due to several reasons, including having differences from the original execution environment, incompatible software libraries, proprietary data and source code, lack of transparency, and the stochastic nature in some software. A study conducted by …

Mapping The Key Players In Kawasaki Disease; Role Of Inflammatory Genes And Protein-Protein Interactions, Wael Hafez, Feras Al-Obeidat, Asrar Rashid, Afsheen Raza, Nouran Hamza, Nesma Ahmed, Marwa M. Abdeljawad, Raziya Kadwa, Abdelhameed Elmesery, Muneir Gador, Dina Khair, Gihan Zina, Fatema Abdulaal, Mina Wassef Girgiss, Maha Abdelhadi, Ahmed Abdelrahman, Mahmad Anwar Ibrahim, Mohamed El Sherbiny

All Works

Background: Kawasaki disease (KD) is a complex acquired condition characterized by systemic blood vessel inflammation that primarily affects children under five years of age. It is clinically diagnosed as a syndrome, making it susceptible to misdiagnoses. Severe complications such as myocardial damage and coronary artery abnormalities can be fatal; thus, early diagnosis is critical for preventing disease progression. Currently, no specific diagnostic test can distinguish KD from viral or bacterial infections. Additionally, the molecular mechanisms underlying the disease remain unclear, hindering the development of targeted therapies. Objective: This study aimed to identify the genetic patterns and molecular mechanisms associated with …

Modeling Literary Connections: Exploring Transregional Resistance In Dalit Poetry, Antara Bhattacharyay

Mathematics, Statistics, and Computer Science Honors Projects

Structuring socio-political identities, the caste system (a graded form of hierarchy) remains entrenched in contemporary Indian society. Dalits, marginalized by the caste system, have expressed their resistance through literature, envisioning substantive equality and social change. In this thesis, I draw on digital humanities methods to examine regional variation in translated Dalit poetry from Bengali, Hindi/Urdu, Marathi, and Tamil languages. I utilize topic modeling—a machine learning algorithm that detects latent semantic structures in a text—as a point of departure for poetry analysis. I observe how topic modeling enables newer readings of the poems, revealing regionally resonant and broader Dalit themes.

Hybridize Functions: A Tool For Automatically Refactoring Imperative Deep Learning Programs To Graph Execution, Raffi Khatchadourian, Tatiana Castro Vélez, Mehdi Bagherzadeh, Nan Jia, Anita Raja

Publications and Research

Efficiency is essential to support responsiveness w.r.t. ever-growing datasets, especially for Deep Learning (DL) systems. DL frameworks have traditionally embraced deferred execution-style DL code—supporting symbolic, graph-based Deep Neural Network (DNN) computation. While scalable, such development is error-prone, non-intuitive, and difficult to debug. Consequently, more natural, imperative DL frameworks encouraging eager execution have emerged but at the expense of run-time performance. Though hybrid approaches aim for the "best of both worlds," using them effectively requires subtle considerations to make code amenable to safe, accurate, and efficient graph execution—avoiding performance bottlenecks and semantically inequivalent results. We discuss the engineering aspects of a …

Noninvasive Assessment Of The Tumor Using Cfdna, Irfan Alahi

McKelvey School of Engineering Graduate Student Theses & Dissertations

Next-generation high-throughput sequencing, which is increasingly generating vast amounts of genomic data, offers opportunities for a deeper understanding of the multifaceted nature of cancer and, hence, better patient care. However, the inherently complex and heterogeneous nature of cancer and the significant challenges in the generated data demand advanced data-driven frameworks to decode the molecular underpinnings of cancer. Moreover, the undeniable need for non-invasive approaches presents additional technical challenges in this domain. This dissertation proposes novel frameworks addressing three key challenges in computational oncology. The first study of this dissertation develops a data-driven algorithm to identify stemness signatures in metastatic castration-resistant …

Evaluating And Applying Coherence Models: Llms As Coherence Evaluators And Neural Entity Grids As Noun Entity Shift Indicators, Elyas A. Amin

Theses and Dissertations

This thesis investigates computational approaches to discourse coherence through two interconnected studies. First, we evaluate the capabilities of Large Language Models (LLMs) as coherence evaluation models across real-world textual data domains. Our experiments with GPT-4o, GPT-3.5, Llama, and Mistral models reveal that while LLMs significantly outperform traditional entity grid methods (55% improvement in F1 scores), their performance varies substantially across domains and coherence levels. Chain-of-thought prompting unexpectedly decreased performance, and fine-tuning experiments demonstrated improved detection of low and high coherence texts but diminished performance on medium coherence cases. In our second study, we explore the practical application of entity grid-based …

Optimizing Small Ai Models For Biomedical Tasks Through Efficient Knowledge Transfer From Large Domain Models, Girish Sundaram

Theses and Dissertations

The PICO (Population, Intervention, Comparison, Outcome) framework is a widely adopted methodology for structuring clinical research questions and extracting relevant information from unstructured medical texts. However, traditional approaches for PICO classification demand computationally expensive domain-specific language models, such as BioBERT and ClinicalBERT, which require extensive training and large annotated datasets. This dissertation introduces Distilled Rapid Embedding Transfer (DRET), a novel knowledge transfer method designed to enable resource-constrained domain adaptation. DRET aims to efficiently transfer biomedical domain knowledge from large, specialized models to a compact, general-purpose model, DistilBERT, thereby enhancing its ability to perform domain-specific tasks without access to the original …

Under Pressure: A Quantitative Approach To Measuring Clutch Performance In The Nba, Jack Dell'isola

Honors Projects in Information Systems and Analytics

This research investigates the existence and relevance of clutch performance in the 2023-2024 NBA regular season. Players are analyzed both individually and against league averages to determine their clutch performance levels using an original "clutch score formula". This research aims to answer the questions of whether clutch performance is a real phenomenon, how individual player performance is affected in clutch time, and to determine a formula that can effectively predict the winner of the Clutch Player of the Year Award. The findings and formulas developed in this research help to shed light on the complexities of clutch performance, which has …

Abel Inversion Comparison Of Geant4 Simulation And Ozone Production Using Cavity Ringdown Spectroscopy In Nitrogen/Oxygen Mixtures In The Presence Of Alpha Radiation, Sidney John Gautrau

Dissertations

The effects of radioactive materials on atmospheric gases have been a topic of interest for years. Radioactive materials ionize the surrounding air, and subsequent reactions lead to molecules such as ozone and nitrogen oxides. The presence of these species above background levels can be used as a marker for radioactive materials which has desirable defense applications like remote detection of radioactive materials. The molecules created in the presence of radioactive materials have been quantified in literature using G-values, which is the number of molecules of a product produced per 100 eV of deposited energy. In this work, Cavity Ringdown Spectroscopy …

Designing An Interactive Exit Ticket System To Enhance Learning In Engineering Education, Tapanga Witt

McNair Scholars Manuscripts

Within Grand Valley State University's (GVSU) Padnos College of Engineering, many first-year Engineering courses consistently see pass rates below 70%, signaling a need for stronger academic support. This is an issue across many universities; students are underprepared and face a lot of challenges with workload, pace, and independence due to the transition from high school to college (Flanigan, 2024). For this project, I designed and developed a website-based exit ticket system to support student reflection and instructor feedback. Using UX design principles, the platform offers a weekly self-reflection form that recommends resources like tutoring, office hours, or study groups. Gamification …

Assessing Perceived Safety Of Non Motorized Travel With Virtual Reality, Vahid Balali, Sahand Fathi

Mineta Transportation Institute

Cycling is increasingly advocated as a healthier and more sustainable mode of transportation, as reflected in both scholarly literature and policy initiatives. Nonetheless, the escalation in bicyclist crash fatalities underscores deficiencies in extant roadway designs that inadequately safeguard these vulnerable users. A persistent challenge in the examination of bicyclist safety, behavior, and comfort is the paucity of comprehensive cycling data. To enhance understanding of cyclists' behavioral and physiological responses safely and efficiently, this investigation utilizes a bicycle simulator within an immersive virtual environment (IVE). Off-the-shelf sensors are employed to evaluate cyclists' performance metrics (speed and lane position) and physiological responses …

Generative Artificial Intelligence Dependency: Scale Development, Validation, And Its Motivational, Behavioral, And Psychological Correlates, Adalia Yin Hui Goh

Dissertations and Theses Collection (Open Access)

The growing integration of generative artificial intelligence (AI) into everyday life has raised questions about its potential psychological and behavioral consequences. The present research develops and validates the Generative AI Dependency Scale, a multidimensional tool developed to assess individual differences in dependency on generative AI systems. Across six studies involving 1,223 participants from the United States and Singapore, the Generative AI Dependency Scale demonstrated strong psychometric properties, including a stable three-factor structure (cognitive preoccupation, negative consequences, withdrawal) and good test-retest reliability (ICC = .85). Confirmatory factor analysis supported a higher-order dependency construct, and scalar measurement invariance was established across sex …

Cuegen: Customizing Sensor Captions For Neon Bending Tutorials, Gunnika Kapoor

2025 Spring Honors Capstone Projects - Archive

Methods of knowledge transfer that rely primarily on visual and/or auditory formats do not effectively convey context-specific or implicit skills, known as tacit skills. This limits knowledge transfer. In this work, the use of customizable pitch captions and spatial audio vibration captions is proposed to aid in conveying this tacit knowledge for neon glass bending video tutorials. Such a system is designed to provide users with greater control and support, which may maximize the information they obtain from, improve the autonomy they have with, and experience they have with a learning tool. As such, a system interface was developed that …

Navigation Of Unmanned Aerial Vehicle Using Computer Vision In Raytheon Drone Competition, Joseph R. Pavlik Iii

2025 Spring Honors Capstone Projects - Archive

A major problem with using GPS to navigate an unmanned aerial vehicle is that GPS signals do not accurately work while inside a building. This work presents the usage of the Simultaneous Localization and Mapping library, ORB-SLAM2, in C++ to solve this issue. By using the camera attached to the unmanned aerial vehicle, a map of the area covered by the drone will be created, and landmarks in area will be utilized to navigate throughout the interior of the building without the GPS. Based on previous studies, this navigation method should be viable. Preliminary tests show that this method will …

Predicting Cardiac Resynchronization Therapy Response: Development And Validation Of A Single Photon Emission Computed Tomography-Based Nomogram, Zhongwei Jiang, Zhongqiang Zhao, Zhuo He, Qiushi Chen, Ju Bu, Chunxiang Li, Dianfu Li, Chang Cui, Weihua Zhou, Huiyuan Qin, Cheng Wang

Michigan Tech Publications

Background: Cardiac resynchronization therapy (CRT) is an effective treatment for patients with drug-refractory heart failure. However, more than thirty percent of patients do not benefit from CRT. This study aimed to develop and validate a novel model based on single photon emission computed tomography (SPECT) phase analysis features to predict CRT response. Methods: We identified 163 CRT patients who received gated resting SPECT myocardial perfusion imaging (MPI) between 2010 and 2020 at The First Affiliated Hospital of Nanjing Medical University. All variables were first processed by univariate logistic regression, and those with a P value < 0.05 were retained. The selected variables were subsequently used in the least absolute shrinkage and selection operator (LASSO) regression to construct a predictive model, which was then represented as a nomogram. Nomogram performance was assessed via receiver operating characteristic (ROC) curves, calibration curves, and decision curve analyses (DCAs). Internal validation was performed by bootstrapping with 1,000 replicates. Results: Of the 163 patients, 93 (57.1%) responded to CRT during follow-up. Responders had a wider QRS complex duration (QRSd) (164.80 vs. 154.51 ms, P=0.003), fewer premature ventricular contractions (PVCs) (1,392.98 vs. 2,283.60, P=0.003), lower prevalence of non-sustained ventricular tachycardia (NS-VT) (45.2% vs. 77.1%, P< 0.001), and better cardiac function [based on N-terminal pro-B-type natriuretic peptide (NT-proBNP), New York Heart Association (NYHA), and left ventricle (LV) parameters] compared to non-responders. Univariate logistic regression revealed 14 variables significantly associated with CRT response (all P< 0.05). The area under the ROC curve (AUC) value for the nomogram was 0.845 [95% confidence interval (CI): 0.785–0.906; sensitivity: 0.771; specificity: 0.849]. Internal validation yielded a mean AUC of 0.814 (95% CI: 0.777–0.836). The calibration curve demonstrated strong consistency between the predicted and observed outcomes. DCA revealed that the nomogram consistently provides a net benefit over the baseline, demonstrating its high practical value in clinical decision-making. A web-based dynamic nomogram (https:// jzw20000624.shinyapps.io/CRTpredictionmodel/) was developed for clinical application. Conclusions: We developed and validated a SPECT-based prediction model for predicting CRT response, which can assist clinicians in optimizing CRT candidacy preoperatively. Pacing at the latest contraction and relaxation segments, while avoiding scarred regions and optimizing preoperative status, is anticipated to improve CRT response.

Fairness In Recommender Systems: Balancing Bias In Academic Paper Selection, Zachary Bergin

Electrical Engineering and Computer Science Undergraduate Honors Theses

Bias in academic paper selection remains a consistent issue, even within processes designed to promote fairness, such as double-blind peer review, bias stays persistent. In this paper we investigate demographic bias while particularly focusing on racial bias in the process of selecting academic papers and explore the impact of fairness aware recommender systems on the demographic parity. To build an effective system our focus is on the Special Interest Group on Computer Human Interaction (SIGCHI) a pillar in the community, we develop a neural network-based recommender system that uses real demographic data collected by other systems withing the context of …

Cyber Resiliency Framework And Mechanisms For Software Defined Tactical Networks, Anthony Castanares

Open Access Theses & Dissertations

Traditional tactical networks fail to achieve cyber resiliency for many reasons, but the most prevalent causes include flat designs, the absence of cyber detection capabilities at the lowest level, and immutable resource allocations after instantiation. These design choices allow network threats direct visibility to each device on the network, and the lack of detection allows infections to proliferate. Furthermore, tactical battlefield networks are difficult to secure because of the lack of persistent oversight by an intelligent agent that can exercise control over the network's topology or resources in real-time. However, advances in software-defined networking (SDN) provide an opportunity to address …

Enhancing Security And Resiliency In Operational Technology Environments Through Network Slicing And Federated Learning, Brian Giovanni Rodiles Delgado

Open Access Theses & Dissertations

The growing convergence of Information Technology (IT) and Operational Technology (OT) within Industry 4.0 environments has introduced new demands on industrial network infrastructure. As cyber-physical systems become increasingly interconnected, ensuring the secure, timely, and efficient exchange of critical data is essential. This thesis explores how network slicing, a method of creating isolated virtual network segments, can be applied within OT environments to address challenges such as latency, security, and resource allocation.

The first research question addressed in this thesis is: How can OT networks take advantage of NFV and SDN technology to become cyber resilient? This study examines the operational, …

Understanding The Impact Of Ransomware On Biotechnology, Tswvyim Vang

Electronic Theses, Projects, and Dissertations

Biotechnology encompasses the use of research on both biology and technology to create products that can advance in areas such as healthcare and agriculture. Because of the technology and products that arise from the use of biotechnology, the industry is especially targeted by cyber-attacks. A prominent type of cyber-attack that is utilized by cyber criminals on biotechnology is ransomware. The goal of this project is to determine the impact of ransomware on biotechnology. The research questions posed are: Q1) What are real examples of ransomware attacks that have occurred on biotechnology companies and what patterns can be identified by these …

Artificial Intelligence In Modern Game Development, Karan Raval

ART 108: Introduction to Games Studies

Artificial intelligence has transformed the landscape of game development in ways early pioneers could only imagine. In my project I explore four major phases of AI evolution: classical AI methods, the rise of machine learning, the advent of transformer architectures, and a spirited debate about whether transformers truly think. To illustrate these shifts I use examples like MYCIN, which helped doctors decide treatments, and Deep Blue, which beat a world chess champion. You’ve probably lost track of time exploring an open world that adapts to your choices, right? That sense of immersion is powered by AI behind the scenes. From …

Learning Through Online Participation: From Breakout Rooms To Discord, Makayla Moster

All Dissertations

For software development teams, teamwork is an essential part of their day-to-day lives. However, due to the aftermath of the COVID-19 pandemic, more companies have allowed employees to have more hybrid and remote work options than before. As more companies are adopting hybrid and remote workstyles, we need to ensure that we are preparing the next batch of young software developers to conduct teamwork in remote and hybrid settings. In this dissertation, I address the tools students use for teamwork and how to improve their teamwork inside and outside of the classroom. I present my research on improving student experiences …

A System And Method For Measuring Spatially Varying Surface Appearances With A Study Of Feathers, Jessica Baron-Lis

All Dissertations

Real-world materials, particularly biological structures such as feathers exhibit complex appearances that vary spatially across their surfaces. The field of computer graphics provides a means of understanding such surfaces through material modeling which uses both analytical models and data acquired from light-surface interactions. There are many efforts within the past decade in measuring materials for graphics, but common limitations in these works include not accounting for spatially varying properties and reliance on neural networks and synthetic datasets.

Feathers from modern birds present diverse appearances due to how light interacts with their unique hierarchical microstructures. Variations in those structures lead to …

A Systemic Approach To Maximize Heterogeneous System Performance, Thomas L. Randall

All Dissertations

Continuous increases in high performance computing (HPC) throughput have served as catalysts for industry and scientific advancement in countless manners that have fundamentally shaped our modern world. Our demands on compute resources continue to scale, but the limitations of Ahmdal’s law and Dennard scaling have proven increasingly difficult to overcome when approached solely through hardware or software design. Furthermore, many HPC applications fail to utilize the collective system’s performance, even on the most advanced supercomputers.

However, the resurgence of AI in the industry has promoted an explosion of hardware and software codesign that have fueled massive improvements in GPU design …

Analytics Insights From Text: Machine Learning, Ai, And Sentiment Analysis On Beige Books, Charlie Smith

Graduate Theses and Dissertations (2019 - present)

Business analytics is about drawing actionable insights from data. These distinct but connected essays represent a novel approach to explore how natural language processing (NLP) advances and machine learning can transform unstructured text data into actionable conclusions. Essay 1 provides a broad framework. Essay 2 strengthens the sentiment analysis with the most recent artificial intelligence methodologies for capturing nuanced sentiment in complex texts. Essay 3 applies those insights to forecast recessions using topics that can be readily interpreted and applied.

The research demonstrates how these methodologies can be applied to enhance understanding of the same dataset, Beige Books. Published by …

Comparative Analysis Of Regression And Random Forest Models For Player Performance Prediction In The Mls, Joshua Clement Madeti

Senior Honors Theses

Advanced technology and analytics have transformed the world and have benefited several industries throughout, the sport industry being one of them. Data is constantly generated during sports and requires post-game or post-season analysis which is crucial to team and player success. In this paper, the researcher will focus on the impact of analytics on soccer and soccer players. With over three billion active fans, soccer is the most famous sport in the world yet, when it comes to analytics, it is lagging. The thesis includes a comparative study of multiple linear regression and random forest regression to explore whether these …