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Full-Text Articles in Entire DC Network
Evaluating Generative Ai-Based User Interfaces Using An Integrated Neutrosophic Multi-Criteria Decision-Making Framework, Nada Mohamed, Alshaimaa A. Tantawy
Evaluating Generative Ai-Based User Interfaces Using An Integrated Neutrosophic Multi-Criteria Decision-Making Framework, Nada Mohamed, Alshaimaa A. Tantawy
Neutrosophic Systems with Applications
User Interface (UI) design can be seen as an essential aspect of human-computer interaction (HCI) and makes communication easier between people and technology. In today's digital economy, interface quality has become one of the most important business concerns, since it has a direct impact on customer satisfaction and retention while affecting revenue. Although creating user-centered and accessible interfaces is crucial, doing so is a difficult and time-consuming process, which leads to burnout for many usability professionals. Although conventional artificial intelligence (AI) was utilized for design assessment and automation, the arrival of generative AI technology has created new possibilities for automated …
Digraphicsoft Sets And Bidigraphicsoft Sets: Directed And Bidirected Extensions Of Graphicsoft Modeling, Takaaki Fujita, Ajoy Kanti Das, Suman Das, Sankar Prasad Mondal, Volkan Duran, Mithun Datta
Digraphicsoft Sets And Bidigraphicsoft Sets: Directed And Bidirected Extensions Of Graphicsoft Modeling, Takaaki Fujita, Ajoy Kanti Das, Suman Das, Sankar Prasad Mondal, Volkan Duran, Mithun Datta
Neutrosophic Systems with Applications
Uncertainty has been modeled through a wide variety of mathematical frameworks, including fuzzy sets, neutrosophic sets, rough sets, and plithogenic sets. Among these approaches, soft sets offer a parameterized representation of uncertain information and have inspired numerous extensions, such as multisoft sets, double-framed soft sets, hypersoft sets, SuperHyperSoft sets, TreeSoft sets, ForestSoft sets, IndetermSoft sets, and IndetermHyperSoft sets.
This paper focuses on GraphicSoft Sets, which extend the classical soft-set framework by assigning a subset of the universe to each subgraph of an attribute graph. In this way, relationships among attributes are incorporated directly into the parameterized model. Building on …
Neutrosophic Time-Truncated Acceptance Sampling Plans Based On The Exponentiated Weibull Distribution For Reliability Applications, Divya P.R., Preethi John
Neutrosophic Time-Truncated Acceptance Sampling Plans Based On The Exponentiated Weibull Distribution For Reliability Applications, Divya P.R., Preethi John
Neutrosophic Systems with Applications
Classical acceptance sampling plans require precisely specified parameter values, an assumption routinely violated by measurement uncertainty and gauge imprecision in practice. This article develops Neutrosophic Time-Truncated Acceptance Sampling Plans (N-TTASP) for the Exponentiated Weibull (EW) distribution by representing the scale parameter as a neutrosophic interval. The neutrosophic sample size nN ∈ [nL, nU] and acceptance number cN ∈ [cL, cU] are obtained by minimizing n_U subject to dual producer and consumer risk constraints on the neutrosophic Operating Characteristic interval. A new indeterminacy ratio η is introduced as a …
Where Do Ai Coding Agents Fail? An Empirical Study Of Failed Agentic Pull Requests In Github, Ramtin Ehsani, Sakshi Pathak, Shriya Rawal, Abdullah Al Mujahid, Mia Mohammad Imran, Preetha Chatterjee
Where Do Ai Coding Agents Fail? An Empirical Study Of Failed Agentic Pull Requests In Github, Ramtin Ehsani, Sakshi Pathak, Shriya Rawal, Abdullah Al Mujahid, Mia Mohammad Imran, Preetha Chatterjee
Computer Science Faculty Research & Creative Works
AI coding agents are now submitting pull requests (PRs) to software projects, acting not just as assistants but as autonomous contributors. As these agentic contributions are rapidly increasing across real repositories, little is known about how they behave in practice and why many of them fail to be merged. In this paper, we conduct a large-scale study of 33k agent-authored PRs made by five coding agents across GitHub. (RQ1) We first quantitatively characterize merged and not-merged PRs along four broad dimensions: 1) merge outcomes across task types, 2) code changes, 3) CI build results, and 4) review dynamics. We observe …
Vision Transformers And Convolutional Neural Networks For Land Use Scene Classification, Arun D. Kulkarni
Vision Transformers And Convolutional Neural Networks For Land Use Scene Classification, Arun D. Kulkarni
Computer Science Faculty Publications and Presentations
Land use scene classification (LUSC) from remote sensing imagery plays a critical role in environmental monitoring, urban planning, and sustainable resource management. In recent years, deep learning methods have significantly advanced the state-of-the-art, with Convolutional Neural Networks (CNNs) dominating the field because of their strong ability to capture local spatial features. However, the emergence of Vision Transformers (ViTs) has introduced a new paradigm that models long-range dependencies through self attention mechanisms, potentially enabling improved global context understanding. This study presents a comparative assessment of Vision Transformers and CNN-based architectures for remote sensing land use scene classification. Representative CNN models, such …
A Visitation Grid For Complete Coverage Foraging In Robot Swarms, Arturo Gonzalez, Yifeng Gao, Li Zhang, Qi Lu
A Visitation Grid For Complete Coverage Foraging In Robot Swarms, Arturo Gonzalez, Yifeng Gao, Li Zhang, Qi Lu
Computer Science Faculty Publications
The complete collection of sparse resources in large, unknown environments remains a challenging problem for autonomous robot swarms. Previous studies have shown that a substantial portion of total mission time is consumed during the final stage of collection, where only a small fraction of randomly scattered resources remain. Consequently, many existing swarm foraging algorithms (search and collection) focus on collecting most resources within a limited time window, rather than improving end-stage efficiency for collecting all resources. We propose a grid-based stochastic foraging strategy that explicitly reduces redundant visits and accelerates late-stage collection. The unknown search area is partitioned into a …
Attention-Based Ensemble Deep Learning Model For Arabic And English Fake News Classification, Ameer Alhaq Alshamery
Attention-Based Ensemble Deep Learning Model For Arabic And English Fake News Classification, Ameer Alhaq Alshamery
Journal of Intelligent Informatics, Networking, and Cybersecurity
It is difficult to classify articles as fake news since one article may consist of true facts with only some statements being fake. Moreover, classification becomes complicated for the Arabic language owing to its morphology and several ways of spelling, as well as the lack of well-classified and marked data sets. This paper presents an Ensemble Deep Learning Model (EDLM) used for Arabic and English fake news classification. The EDLM consists of CNN, Bi-LSTM with attention, and Bi-GRU with attention networks. Each of them produces one probability of the article, which is then summed up to a final probability via …
A Mathematical Decision-Making Framework For Athlete Development In A Collegiate Taekwondo Community: Prioritizing Coaching Interventions Using Statistical Analysis And The Analytic Hierarchy Process, King Harold A. Recto, Hazel Jade L. Antonio, Jhyrald Anthony P. Dalida
A Mathematical Decision-Making Framework For Athlete Development In A Collegiate Taekwondo Community: Prioritizing Coaching Interventions Using Statistical Analysis And The Analytic Hierarchy Process, King Harold A. Recto, Hazel Jade L. Antonio, Jhyrald Anthony P. Dalida
Electronics, Computer, and Communications Engineering Faculty Publications
Athlete development within collegiate sports communities requires informed decisions regarding the prioritization of coaching interventions and allocation of developmental resources. However, such decisions are frequently guided by experience and intuition, limiting opportunities for systematic and evidence-based decision-making. This study develops a mathematical decision-making framework for athlete development by integrating statistical analysis and the Analytic Hierarchy Process (AHP) within a collegiate taekwondo community. Data were collected from 25 collegiate taekwondo athletes who satisfied established eligibility criteria, including participation in University Athletic Association of the Philippines (UAAP) competitions during the previous three seasons. Athletes evaluated coaching practices across five dimensions: Training and …
A Data-Driven Framework For Mitigating Breast Cancer Overdiagnosis: From Estimation To Risk-Adjusted Computer-Aided Diagnosis, William M. Brown Jr.
A Data-Driven Framework For Mitigating Breast Cancer Overdiagnosis: From Estimation To Risk-Adjusted Computer-Aided Diagnosis, William M. Brown Jr.
LSU Doctoral Dissertations
In Computer-Aided Diagnosis (CAD) of cancer, standard cost metrics (false-positives and false-negatives) fundamentally fail to account for overdiagnosis. Overdiagnosis is a critical scenario where a disease is correctly detected (true-positive) but is biologically indolent and would never have caused the patient harm or symptoms. While widely recognized in the medical community as a major healthcare crisis driving stressful and invasive overtreatment, overdiagnosis remains severely under-researched within computer science and engineering. This dissertation addresses this interdisciplinary gap by defining the three key computational challenges of overdiagnosis: (i) accurate estimation, (ii) harm quantification, and (iii) algorithmic mitigation. To overcome the estimation challenge, …
Information Theory Analysis Of Water Vapor Stable Isotopes From The Sail Campaign, Matthew John Rybecky
Information Theory Analysis Of Water Vapor Stable Isotopes From The Sail Campaign, Matthew John Rybecky
Earth and Planetary Sciences ETDs
Understanding the processes that control water vapor isotopic composition in mountain environ- ments is essential for interpreting isotope records and predicting water resource responses to cli- mate change. This thesis applies information theory to continuous, high-resolution water vapor stable isotope measurements from the Surface Atmosphere Integrated Field Laboratory (SAIL) campaign in the East River watershed of Colorado’s Upper Gunnison Basin, spanning the winter- to-spring transition of 2022–2023. The analysis employs Shannon entropy, mutual information, transfer entropy, and joint transfer en- tropy (JTE) to quantify how environmental variables, including surface meteorology, radiation, tur- bulent fluxes, and ERA5 reanalysis products, transfer information …
Ai-Powered Resume Screening, Sang Suh, Numery Zaber
Ai-Powered Resume Screening, Sang Suh, Numery Zaber
Faculty Publications
Traditional resume screening is manual, slow, and susceptible to bias, and it struggles to keep pace with today’s application volumes. This paper presents a dual-engine, AI-powered resume screening system designed for transparency and reproducibility. The primary (classical) pipeline encodes resumes and job descriptions using Sentence-BERT (SBERT), computes a resume–job match score via cosine similarity, classifies candidates into 25 job categories using XGBoost, and provides model interpretability through SHAP. In parallel, a prompted large language model (LLM) baseline (GPT-4o/4o-mini) outputs a match score and predicted category for comparative analysis. A Streamlit-based interface integrates both engines to support recruiter workflows and human-in-the-loop …
Surveyception: An Exploration Of Deceptive Survey Forms, Muhammad Danish
Surveyception: An Exploration Of Deceptive Survey Forms, Muhammad Danish
Computer Science ETDs
Survey platforms such as Google Forms and Microsoft Forms are widely used for feedback, data collection, and engagement, but scammers increasingly exploit them to distribute phishing and deceptive attacks. This thesis presents a large-scale study of survey-form abuse across ten major providers. We collected 140,000 forms from three sources: public posts on X, search-engine results, and web pages from the top 10 million DomCop-ranked domains. Using automated filtering and manual qualitative review, we identified 2,645 forms requesting sensitive information and classified 566 as scams. These forms used techniques including phishing, private-secret theft, account and personal-data harvesting, financial deception, and psychological …
A Hybrid Deep Learning Model Combining Cnn And Extreme Learning Machine For Cyberattack Classification, Israa S. Kamil
A Hybrid Deep Learning Model Combining Cnn And Extreme Learning Machine For Cyberattack Classification, Israa S. Kamil
Journal of Intelligent Informatics, Networking, and Cybersecurity
As ransomware attacks and zero-day exploits grow sophisticated, the need for intelligent, accurate systems to detect such threats becomes clearer. In this paper, a hybrid learning model based on Convolutional Neural Networks (CNNs) and Extreme Learning Machine (ELM) is presented to improve multiclass classification performance for cybersecurity applications. The framework combines CNNs' hierarchical feature learning with ELMs' fast classification. An attention mechanism that assigns weights to each feature based on importance is included in the final model. The hybrid model performed well on the metrics: precision = 0.97, recall = 0.98, and F1- score = 0.97, and, as expected from …
Towards Intelligent Iot-Ndn Security: Ai-Driven Pit Attack Detection And Cache Attack Analysis, Sura Haidar Ali, Alaa Shawqi Jaber
Towards Intelligent Iot-Ndn Security: Ai-Driven Pit Attack Detection And Cache Attack Analysis, Sura Haidar Ali, Alaa Shawqi Jaber
Journal of Intelligent Informatics, Networking, and Cybersecurity
Beginning with Named Data Networking (NDN), an early form of information-centric networks, the paradigm of how data is transmitted over a network was changed through the use of ``content-based'' communication instead of ``host-based'', while creating native caching at intermediate points along the path to each destination, and improving upon the security of all previous paradigms. NDN contains many inherent benefits such as caching, security, etc., but like any other paradigm, NDN creates new types of vulnerabilities, particularly within some of the key elements of this paradigm; namely the Content Store (CS), Pending Interest Table (PIT), and the Forwarding Information Base …
Stop Blaming My Users: Illumination Of The Technocentric Mythos Bias, Ervin H. Frenzel, Richard Lightcap
Stop Blaming My Users: Illumination Of The Technocentric Mythos Bias, Ervin H. Frenzel, Richard Lightcap
Journal of Cybersecurity Education, Research and Practice
Abstract -This conceptual essay addresses the need for systemic and systematic transdisciplinary analytical techniques within cybersecurity and technical security. This conceptual essay is contingent upon recognition that cybersecurity is not simply technical in nature, it does not need an adversary, and more importantly it is based upon systems engineering and systems thinking. The essay contributes a socio-technical attribution chain and field-specific ontology/taxonomy which distinguish user-triggered events from root causes, latent conditions, technical debt, validation failures, governance failures, and attribution bias before assigning responsibility to end users. It systematically defines an ontology inclusive of developer technical debt, organizational debt arising from …
Escaping The Cyberstorm: A Gamified Social Engineering Training Program, Noah Mcclanahan, Fadi Abu-Amara, Ali Khattab, Travis Jett, Andre Jackson
Escaping The Cyberstorm: A Gamified Social Engineering Training Program, Noah Mcclanahan, Fadi Abu-Amara, Ali Khattab, Travis Jett, Andre Jackson
Journal of Cybersecurity Education, Research and Practice
In this research work, we explored the effectiveness of gamification in improving cybersecurity awareness and training users on targeted social engineering attacks. Traditional cybersecurity training focuses on lectures and videos. These training methods may not actively engage employees, which reduces their knowledge retention and ability to recognize social engineering attacks. This lack of involvement is a concern, as social engineering continues to be one of the most prevalent attack methods faced by end-users. A gamified training program, Escaping the Cyberstorm, was developed using the Godot game engine to address key challenges in spreading cybersecurity awareness. The game includes real-life …
Artificial Intelligence Mechanisms In The Limit Of Crimes And Law Enforcement, Saad Mefleh Alsuwaileh
Artificial Intelligence Mechanisms In The Limit Of Crimes And Law Enforcement, Saad Mefleh Alsuwaileh
Journal of Police and Legal Sciences
This study explores the potential of employing technological mechanisms and modern innovations brought about by the Fourth Industrial Revolution, particularly advancements in the field of information technology, in the domains of criminal investigation, crime prevention, and law enforcement. It aims to analyze the impact of these technologies on crime control efforts and the promotion of justice.
The significance of the study lies in highlighting the power of technology in processing and analyzing massive volumes of data with greater speed and accuracy, thereby enhancing the efficiency of criminal investigations and the ability to predict and prevent crimes. The core research question …
Applying Artificial Intelligence Within Decision Support Systems And Its Role In Improving Proactive Thinking And Reducing Security Threats: The Mediating Role Of Data Quality, Hany Shaaban El Anany
Applying Artificial Intelligence Within Decision Support Systems And Its Role In Improving Proactive Thinking And Reducing Security Threats: The Mediating Role Of Data Quality, Hany Shaaban El Anany
Journal of Police and Legal Sciences
The study aimed to identify the impact of applying artificial intelligence within decision support systems in improving the level of proactive thinking and reducing security threats in government institutions in the Arab Republic of Egypt, as well as to examine the mediating role of data quality in this relationship, at a significance level of (α ≤ 0.05). The study sample consisted of (360) participants working in the departments of information technology, decision support, and cybersecurity within government institutions and national authorities that rely on AI-enhanced decision support systems.
The study adopted the descriptive analytical method and used a questionnaire as …
Match Made In Ml: Developing Compatibility Relationships In Evidential Reasoning Approaches With Machine Learning, Ella Jolie Thomas
Match Made In Ml: Developing Compatibility Relationships In Evidential Reasoning Approaches With Machine Learning, Ella Jolie Thomas
Master's Theses
The presented expectation maximization informed evidential reasoning model extends the ability of the evidential reasoning calculus to support decision making by integrating an adaptive model learning capability. Compatibility relationships in Evidential Reasoning models are traditionally built by human domain experts. This process is labor-intensive, especially for large and complex models. Additionally, when new data becomes available, compatibility relationships must be reconstructed. Using machine learning and the expectation maximization algorithm, it is demonstrated that compatibility relationships can be constructed that learn relationships between domain knowledge that is used to make decisions. Using drug development as a domain of application, a traditional …
Accessibility Fairness Practices In Ai Applications For People With Disabilities, Megan Gross
Accessibility Fairness Practices In Ai Applications For People With Disabilities, Megan Gross
Master's Theses
Advancements in artificial intelligence (AI) improve the lives of people every day with tools like the auto-captioning of videos, improved screen-reader capabilities, and advanced mobility control through speech. However, are all groups of people benefiting from AI or are some being overlooked and left out? Although AI tools made for people with disabilities (PWDs) have improved their lives, AI for the general population generally ignores the experiences of PWDs, making them unable to interact with and benefit from technology. This research evaluates ChatGPT and Gemini in Gmail for usability fairness and analyzes how current regulations and development processes fail to …
Can Machines Testify? Llms And The Boundaries Of Testimonial Epistemology, Michael J. Cummins
Can Machines Testify? Llms And The Boundaries Of Testimonial Epistemology, Michael J. Cummins
Philosophy Summer Fellows
As Large Language Models and AI chatbots become increasingly prevalent, pressing questions are raised about whether beliefs formed through LLM interactions carry the same epistemic weight as beliefs formed through human testimony. How we answer this question depends on whether LLMs can function as testifiers, a role which is typically assumed to require a human or human-like agent. This assumption has gone largely unexamined, yet its consequences are significant: if LLM outputs cannot constitute testimony, then the justificatory tools of testimonial epistemology are unavailable to any beliefs formed through LLM interaction. This paper challenges that assumption. It first argues that …
Entity Labels Are Not Entity Signals: A Framework For Observable Relevance In Document Re-Ranking, Utshab Kumar Ghosh, Shubham Chatterjee
Entity Labels Are Not Entity Signals: A Framework For Observable Relevance In Document Re-Ranking, Utshab Kumar Ghosh, Shubham Chatterjee
Computer Science Faculty Research & Creative Works
Entity-aware document retrieval uses query-associated entities as ranking signals, assuming that semantically relevant entities are also useful retrieval signals. We show this assumption is insufficient - and explain why. Unlike terms, which are ground-truth observations, entity links are hypotheses produced by an imperfect linker: an entity can be topically central yet provide no discriminative signal if the linker fires indiscriminately across relevant and non-relevant documents. We formalize this as a distinction between Conceptual Entity Relevance (CER) - whether an entity is topically related to a query - and Observable Entity Relevance (OER) - whether its observed presence in a collection …
Stylometric And Formal Patterns In The Scholarly Impact Of Scientific Literature, Joshua Ange, Eric Godat, Rajani Sudan
Stylometric And Formal Patterns In The Scholarly Impact Of Scientific Literature, Joshua Ange, Eric Godat, Rajani Sudan
SMU Journal of Undergraduate Research
Scientific communication is typically tied to promoting public engagement and interest in science, increasing scientific literacy, and playing an essential role in policymaking. The success of public communication of scientific findings is largely associated with secondary characteristics of research (e.g. the style of writing and presentation), rather than the primary content or research quality. But it is unclear to what extent the success of scientific literature intended for working scientists is influenced by those same secondary characteristics. Does the writing style of scientific articles impact their success in academic spheres? In this study, we explore the stylometric and formal characteristics …
Image Fusion Based On Deep Learning With Different Locations And Sizes Of Objects, Baneen Al-Kalabi, Tawfiq Al-Assadi
Image Fusion Based On Deep Learning With Different Locations And Sizes Of Objects, Baneen Al-Kalabi, Tawfiq Al-Assadi
Journal of Intelligent Informatics, Networking, and Cybersecurity
Multi-focus image fusion combines partially focused images into a single all-in-focus composite. Existing object-based methods assume precise spatial and scale alignment across source images, an assumption that frequently fails in Misaligned Multi-Focus Dataset scenarios due to camera displacement and focal length variation. This paper proposes a novel training-free, object-aware fusion framework to address this limitation through a five-stage pipeline: YOLOv8x detection, SAM2-L segmentation, LoFTR correspondence matching, a novel Scale-Aware Area Resize Algorithm, and GLCM-guided MSB/LSB bit-level fusion. The framework was evaluated on the EDMF benchmark (20 image pairs, synthetically modified to simulate Misaligned Multi-Focus Dataset shifts) and a Misaligned Multi-Focus …
Lossless Medical Image Compression Using Integer Discrete Wavelet Transform With Adaptive Subband Differencing And Context-Adaptive Entropy Coding, Rasha F. Nadhim, Ibrahim Adel Ibrahim, Ashwaq T. Hashim
Lossless Medical Image Compression Using Integer Discrete Wavelet Transform With Adaptive Subband Differencing And Context-Adaptive Entropy Coding, Rasha F. Nadhim, Ibrahim Adel Ibrahim, Ashwaq T. Hashim
Journal of Intelligent Informatics, Networking, and Cybersecurity
From transform-domain decorrelation and adaptive entropy coding, we propose a method for efficient lossless compression of medical images in this work. We implement the Integer Discrete Wavelet Transform (IDWT) to decompose the input image into four subbands of LL, LH, HL, HH, encompassing approximation and directional detail elements, in the initial implementation. It also removes spatial redundancy in image information and decomposes image information into a less correlated and more sparsely distributed set of coefficients. To decrease redundancy further, it proposes a subband-dependent differencing scheme, which decorrelates neighbouring wavelet coefficients with directional prediction. So horizontal differencing is done on LH, …
A Blockchain-Integrated Federated Learning Model And Autoencoder-Based Feature Reduction For Improving Iot Intrusion Detection, Tahseen A. Wotaifi
A Blockchain-Integrated Federated Learning Model And Autoencoder-Based Feature Reduction For Improving Iot Intrusion Detection, Tahseen A. Wotaifi
Journal of Intelligent Informatics, Networking, and Cybersecurity
The rapid growth of Internet of Things (IoT) environments has brought forth a wealth of security challenges in detecting network intrusions in diverse and resource-restricted systems. Privacy, scalability, and single point of failure issues plague traditional centralized intrusion detection solutions. To address these challenges, the study proposes a secure and adaptive intrusion detection model using Federated Learning (FL) and Blockchain, augmented with autoencoder-based feature reduction. The ToN-IoT dataset is pre-processed, and then an unsupervised autoencoder is used to build informative low-dimensional feature representations. The processed data is deployed to various clients to mimic a real federated situation. Every client will …
A Dual- Task Hierarchical Graph Attention Network For Protein-Protein Interaction Sites Prediction, Oras A. Hussein, Eman S. Al-Shamery
A Dual- Task Hierarchical Graph Attention Network For Protein-Protein Interaction Sites Prediction, Oras A. Hussein, Eman S. Al-Shamery
Journal of Intelligent Informatics, Networking, and Cybersecurity
In computational structural biology, it is still very hard to accurately find protein-protein interaction (PPI) sites and estimate how strong the interaction would be. In this research, we provide an innovative two-stage deep learning framework that combines residue-level graph representation learning with protein-level regression to achieve a thorough modeling of protein interactions. Protein structures first encoded as residue graphs, with nodes that stand for amino acids and edges that show how close they are to each other in space. To find binding residues, a deep residual Graph Attention Network v2 (GATv2) uses multi-head attention, residual connections, and Jumping Knowledge aggregation …
Tile-Based Knot Assembly With Celtic!, Divya Bajaj, Ryan Knobel, Juan Manuel Perez, Rene Reyes, Ramiro Santos, Tim Wylie
Tile-Based Knot Assembly With Celtic!, Divya Bajaj, Ryan Knobel, Juan Manuel Perez, Rene Reyes, Ramiro Santos, Tim Wylie
Computer Science Faculty Publications
In this paper we focus on the intersection of tile assembling systems, edge-matching puzzles, combinatorial games, and knot construction and identity. As a basis, we utilize the game Celtic!, which is a 2-player board game where the goal of the game is to construct knots where one knot uses more of a player’s pieces than the other player over all knots. All pieces must build off an existing knot and a valid knot must be closed. We consider three variations: a 0-player self-assembly variation that deterministically places pieces to form a closed knot of some length, a 1-player puzzle variation …
Cytotoxicity Of Bioactive Peptides From Cowpea (Vigna Unguiculata L. Walp) Against Breast Cancer Cells (Mcf-7), Dian R. Ningsih, Zusfahair Zusfahair, Ely Setiawan, Purwati Purwati, Kasta Gurning, Fitri A. Puspita Sari, Elya Widiawati
Cytotoxicity Of Bioactive Peptides From Cowpea (Vigna Unguiculata L. Walp) Against Breast Cancer Cells (Mcf-7), Dian R. Ningsih, Zusfahair Zusfahair, Ely Setiawan, Purwati Purwati, Kasta Gurning, Fitri A. Puspita Sari, Elya Widiawati
Karbala International Journal of Modern Science
Cancer is characterized by dysregulated metabolic signaling pathways, leading to uncontrolled cellular proliferation. Current cancer treatments, which involve surgery, radiotherapy, and chemotherapy, still cause adverse systemic toxicities. Accordingly, one possible effort that can be undertaken is to explore safe anticancer substances from protein sources such as peptides. Bioactive peptides can be isolated by hydrolyzing cowpea (Vigna unguiculata L. Walp) protein with trypsin. The objectives of this study were to isolate and fractionate bioactive peptides from cowpea, to determine the anticancer activity of peptide fractions, to identify active peptide fractions as anticancer agents using Liquid Chromatography High Resolution Mass Spectrometry …
Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta
Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta
Karbala International Journal of Modern Science
It has previously been shown that exogenous bacterial ribosomes added to somatic cells and various cancer cell lines generate ribosome-induced cell clusters (RICs) capable of transdifferentiating into multiple cellular lineages. However, the scope of ribosome-induced transdifferentiation in cancer cells remains poorly understood. This study aimed to analyze the effects of exogenous ribosome incorporation on human cancer cell lines, specifically the intestinal epithelial cell line Caco-2 and the hepatocellular carcinoma cell line HepG2. Caco-2 and HepG2 cells were cultured with purified bacterial ribosomes in human ES/iPS cell medium after trypsinization, resulting in the formation of ribosome-induced Caco-2 (RICs-Ca) and HepG2 (RICs-He) …