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Refinements In The Isomer Distribution And Relative Rate Of Sulfonation Of Toluene And Hydrochlorination Of Olefins With Stannic Chloride Catalyst, David George Guillot

Theses and Dissertations

The sulfonation of toluene at -12.5° C. with sulfur trioxide in liquid sulfur dioxide was found to give 10.03 ± 0.20 % ortho, 0.73 ± 0.20 % meta and 89.24 ± 0.20 % para isomers. This isomer distribution was determined by isotope dilution analysis using sulfur-35 enriched sulfur trioxide. After dilution of aliquots of the neutralized sulfonation mixture with pure sodium salts of each of the isomers prepared from the corresponding toluidines, the isomers were converted to the p-toluidine salts, purified by recrystallization, and counted by liquid scintillation counting. The relative rate of sulfonation of toluene compared to benzene was …

Nature Of Non-Biological Decomposition Of Nitrite In Acid Media, Mukkatira Kariappa Mahendrappa

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Curiosity is the cause of investigations, and the thirst for knowledge originates from it. Many times at the end of investigations, the number of questions raised are greater than those for which answers are sought. Therefore, all the information gathered through scientific investigations may not be of value for immediate application in practical life. Nevertheless, no research can be considered less important than the other because the integration of several scientific findings considered less less important at the time of investigation may reveal something of very high significance. Similarly, the study of various transformation reactions that the added fertilizers undergo …

Studies On The Ribosomal Ribonucleic Acids From Mesophilic And Thermophilic Bacteria, Alice A. Holazo

Masters Theses

Introduction

Certain organisms have been known to live at temperatures at which cellular constituents ordinarily sensitive to heat are destroyed. These organisms. called thermophiles (heat-loving), normally live at higher temperature range of the biokinetic zone (10^o-45^oC).

Synthesis And Nuclear Magnetic Resonance Studies Of Some Boron And Nitrogen Substituted Borazines, Michael G. Henk

Master's Theses (1922-2009) Access restricted to Marquette Campus

From the time Stock and Pohland (44) first prepared borazine in 1926 until Schaeffer and Anderson (33) found a convenient method of preparing borazine in 1949, comparatively little work was done with this compound. Since 1949 work with borazine has progressed geometrically. Today there are a large number of borazines known (15, 36). However, fluorine substituted borazines were unknown until 1962 (29) and to this day very little work has been done with fluorine substituted borazines (2, 27, 30). Also, only a few unsymmetrical borazines have been prepared (38, 40, 41, 42). It would be desirable to have a convenient …

Hydrolysis Of Benzohydroxamic Acid, Robert L. Fuller

Masters Theses

Introduction

The hydroxamic acids were discovered in 1869 by H. Lossen¹. The nomenclature, structure, and chemistry of these compounds have been summarized in an excellent review article by Yale².

Spin-Resonance Transitions Of Free Radicals In The Zeeman Region, Juana Vivó Acrivos

Faculty Publications, Chemistry

No abstract provided.

A Method For The Determination Of Solanesol In Tobacco, Ludwig Weissbecker

Master's Theses

The object or this work was to develop a procedure for the quantitative determination of solanesol in the petroleum ether extract of tobacco. The amount of tobacco extracted into petroleum ether is routinely used to differentiate tobacco types. The extraction procedures have been extensively studied by the Association of Official Agricultural Chemists (AOAC) and reported in the United States Department of Agriculture (USDA) Technical Bulletin # 1186.

There is at present no method for the quantitative determination of solanesol. One procedure which comes closest, involves an infrared measurement of the tobacco extract. Because of the presence of other bands, the …

Egg Shell Quality, R J. Bishop

Journal of the Department of Agriculture, Western Australia, Series 4

Recent overseas work and local industry developments indicate that the calcium content of feed for laying hens in Western Australia should be increased to achieve satisfactory egg shell strength.

Age, temperature and breeding are other important influences on egg shell quality.

The Electrical Resistivity Of Different Types Of Glasses, Fadel Youssef Iskandar Assabghy

Archived Theses and Dissertations

No abstract provided.

A Study Of Some Properties Of As2S3 Glass And The Test Of A New Theory Of Glass Formation, Edward Nashed Bolous

Archived Theses and Dissertations

No abstract provided.

Some Properties Of Cerium Borate And Phosphate Glasses In Relation To Structure, M Osama El-Bayoumi

Archived Theses and Dissertations

No abstract provided.

The Activity Of Succinic Dehydrogenase And Indole Acetic Acid Oxidase In Cell-Free Preparations Of Hygrophorous Conicus, Jagdish M. Mehta

Masters Theses

"The enzyme indole acetic acid oxidase is produced by the fungus Hygrophorous conicus when it is grown in the presence of indole acetic acid (IAA) or tryptamine. The IAA acts both as an inducer and a substrate for this intracellular enzyme. The product of the oxidation catalyzed by the IAA oxidase is oxindole acetic acid (OIAA).

The rate of growth and the rate of formation of the enzyme IAA oxidase by H.conicus were studied in different media. Of these, a nitrate medium containing 0.5 per cent Yeast extract (Y.E.) was found to be the best for the production of H.conicus …

Investigation Of The Cis-Trans Isomers Of Tetrachlorodiaquorhodate (Iii) Anion, Kenneth Lee Bridges

Dissertations and Theses @ UNI

A coordination compound, or complex, is formed when an atom, molecule, or ion unites by donating a pair of electrons with another atom, molecule, or ion able to accept the pair. In metal .coordination compounds, a metal-ion is the electron pair acceptor and usually is able to accept more than one pair. The number of electron-pairs which can be used in bonding is called the coordination number. The donor atom, molecule, or ion is called a ligand.

Synthesis Of Benzyl Beta D-Gulopyranosiduronic Acid-(2',3': 4,5)-Oxazolidone-2, Gerald Duane Shryock

University of the Pacific Theses and Dissertations

Although D-glucosamine has been found as a constituent of some antibiotics (28), very little research has been carried out in the area of synthetic preparations. Dutcher (7) recently reviewed the biochemical importance of this class of amino sugars as a constituent of complex antibiotic substances which compose the streptothricin family. For a complete elucidation of these antibiotics, it becomes necessary to investigate thoroughly the synthesis and reactions of the D-glucosamine compounds. Gross et al. (12) have succeeded in preparing the oxazolidone of α-D-glucosamine as well as some derivatives (13) of this compound. The present work reports an attempt to prepare …

The Synthesis Of 4-Spiro-2-Aryloxazolines Of Potential Pharmacological Interest, Paul Waddell Collins

Theses and Dissertations

Numerous and diverse physiological actions are found among 2-oxazoline compounds. No reports of the synthesis or biological testing of 4-spiro-2-aryl-2-oxazolines were found in the literature. On the basis of the known pharmacological activities of certain aza- and diazaspirans, it was felt that 4-spiro-2-aryl-2-oxazolines should possess medicinal activity. In particular, it was reasoned that the combination in a bicyclic spiro structure of the 2-oxazoline ring with rings systems commonly found in synthetic antitussive compounds might result in active antitussive agents.

The aim of this research was the synthesis of a series· of 2-aryl-2-oxazoline-4-spirocyclopentanes and a series of 1'-methyl-2-aryl-2-oxazoline-4-spiro-4’-piperidines. Six members were …

The Occurrence And Distribution Of Methane In The Marine Environment, Larry Philip Atkinson

OES Faculty Publications

The distribution of methane in several anoxic marine environments is described. Maximum concentrations observed were μ mole CH₄-C/liter. The distribution of methane seems to follow that of sulfide. The data indicate that methane is derived from organic compounds not containing nitrogen or phosphorus and that its formation is much slower than that of sulfide.

The Synthesis Of Benzyl N-Carbobenzoxy Beta-D-Glucosaminid Uronic Acid Derivatives, Stuart Martin Block

University of the Pacific Theses and Dissertations

The purpose of this research is the preparation and characterization of derivatives of benzyl N-carbobenzoxy-β-D-glucosaminiduronic acid. Previously the derivatives of benzyl N-carbobenzoxy-α-D-glucosaminid-uronic acid have been prepared by H. Weidmann and H. K. Zimmerman (32). The procedure upon which both these uronic acid syntheses is based has been developed with the utilization of platinum in the selective catalytic oxidation of both the benzyl α- and β-D-glucuronosides. The applicability of this research is in the development of new intermediates for the preparation of new diamino sugars or other natural products.

Capillary Behavior Of Viscous Liquids, Marvin De Young

University of the Pacific Theses and Dissertations

A major problem confronting every investigator who works with synthetic organic chemistry is that of the crystallization of the products obtained. This problem necessitates extensive attention both on the experimental and on the theoretical level. In order to gain an understanding of the behavior of substances in the liquid state, so as to be better able to manipulate them in procedures intended to induce crystallization from complex mixtures, considerable attention has been given to various models of the liquid state. An understanding of the nature of pure liquids would seem to be an essential prelude to any attempt to understand …

Plant-Derived Pigments And Dyes Used By Artists, Samuel C. Rizzetta

Masters Theses

History

Uses of Biologically-derived Products in Painting

Throughout history man has relied heavily on plant-derived materials in the production of paintings. Plant products have been used to fulfill each of the material requirements of painting. The ground or surface upon which an artist applies paint -is usually of plant origin, such as woven fabrics and paper. The ancient Egyptians painted on canvas (from Linum usitatissimum L.), papyrus, (from Cyperus papyrus L.), and wood (Lucas, 1934:149-150, 201-203; Laurie, 1910:17, 31-32).

At the time of Theophilus leather parchment, preferably of horsehide, was popular for painting (Bazzi, 1960:13). After parchment, walls and wooden …

Rearrangements In The Synthesis Of Β-Ketoallyl Amines, Richard P. Rebman

Open Access Master's Theses (through 2010)

The work reported in this thesis is part of an integrated research program in progress at the University of Nebraska dealing with the mechanisms of addition, elimination, and substitution in α, β – unsaturated ketones and their halogen derivatives.

The essential scope of this research is the investigation of the mechanism(s) of substitution by amines on α – (bromomethyl)-chalcone.A knowledge of the mechanism(s) involved would be useful in elucidating some of the factors determining the structure of reaction products observed in other similar systems.

Advisor: Norman H. Cromwell

The Preparation Of 5-Arylazopyrimidines, Frederic Edwin Dutton

Masters Theses

Introduction

The synthesis of 5-arylazopyrimidines was undertaken in search of potential anticancer agents.

While many azo compounds have carcinogenic activity, it has been shown by several workers in this area that some 5-arylazopyrimidines have anticancer properties. S. Hibino(1) has shown that p-(2,4,6-triamino-5-pyrimidinylazo) benzene-sulfonic acid shows promise as an effective anticancer agent when used in conjunction with 6-mercaptopurine and adrenal steroidal hormones. When tested clinically, total remission of the leukemic process was achieved in 85.7% of the cases treated. In comparison, total remission was achieved in only 57.5% of the cases treated with a mixture of 6-MP and the hormone which …

The Synthesis Of Some Decahydronaphthoic Acid Lactones, Robert C. Matejka

Open Access Master's Theses (through 2010)

The diterpenoid acids, dehydroabietic acid, podocarpic acid, abietic acid, and palustric acid, have been synthesized. This thesis records the successful completion of this task which involves a selective epimerization of C.8a. It is hoped that keto lactone on alkylation will give an intermediate of the type C.l epimers which is required for the synthesis of the abietic acid series.

Advisor: D. M. S. Wheeler

The Reaction Of Metal Hydrides With Azoacetates, Thomas H. Althuis

Masters Theses

Introduction

The term aliphatic azo compound refers to those azo compounds in which at least one of the two nitrogen atoms is linked to a tetrahedral, that is, sp³ -hybridized carbon atom. Di-imides, RN=NH, however, are not being considered. Mixed aliphatic-aromatic azo compounds are those in which one nitrogen atom is linked to an sp³ -hybridized carbon atom and the other to an aromatic sp² -hybridized carbon atom. If present, a symmetry element (point or plane) is determined by the mid-point between the two nitrogen atoms.

Study Of The Stereochemistry Of A Carbanion Generated From An Azoacetate, Nguyen Thanh Buu

Masters Theses

Introduction

The reaction of lead tetraacetate with ketohydrazones to form azoacetates has been reported recently by Iffland, Salisbury and Schafer (13) and may be represented by the following equation:

R₂C=N-NH-R' + Pb(0Ac)₄ → R₂C-N=N-R' + Pb(OAc)₂ + HOAc OAc

Of principal interest has been the base-catalyzed decomposition of an azoacetate in a protonic solvent to give a ketone, a hydrocarbon, nitrogen and an acetate salt. The following sequence of steps has been proposed to account for these products (11).

Aminomethylation And Hydroxymethylation Of 6-Mercaptopurine And 6-Alkylthiopurines, Charles P. Bryant

Masters Theses

Introduction

The Mannich reaction and hydroxymethylation were used to prepare analogs of 6-mercaptopurine as possible antimetabolites. Physical and chemical methods were used to elucidate the structures of the compounds prepared.

Scaling In Isoelectronic Molecules, Jerry Goodisman

Chemistry - All Scholarship

A modification of a scaling method introduced for atoms by Ellison enables one to use expectation values calculated for one molecule in calculations of the energy of a second molecule isoelectronic to the first. In going from Hz to Hez2+t,h e results are only fair, but in going from LiF to BeO, the results are suffeciently good to allow prediction of equilibrium distance and several expectation values as well as energy. The dipole moment is a notable exception, which reveals one basic dissimilarity between the two molecules, the ionic character. LiF dissociates to ions, Be0 to neutral atoms, causing our …

Thermodynamics Of Proton Ionization In Aqueous Solution I. A Precision Thermometric Titration Calorimeter ; Ii. Entropy Titration : A Calorimetric Method For Equilibrium Constant Determinations ; Iii. H And S Values For Carboxylic Acid Proton Ionization At 25c ; Iv. Site Of Proton Ionization From Adenosine, Lee D. Hansen

Theses and Dissertations

The design, construction, and calibration of a precision thermometric titration calorimeter is described. This calorimeter was tested by determining the enthalpy change for ionization of water. The result, 13.34 ±0.03 kcal/mole (standard deviation), is in exact agreement with the best literature values. This standard deviation indicates that, using this calorimeter, ΔH values can be determined with an accuracy of ±0.0.5 kcal/mole. A calorimetric procedure has been developed for the, simultaneous determination of the equilibrium constant, the enthalpy change, and the entropy change for a chemical reaction from a single titration (Entropy Titration). This procedure has been tested by determining pK, …

Liquid Scintillators: Some 3-Aryl-L,2-Dihydronaphthalenes, 3-Aryl-1,2-Dihydro-4-Methylnaphthalenes, 3-Aryl-1,2-Dihydrophenanthrenes And 3-Aryl-1,2-Dihydro-4-Methylphenanthrenes: Steric Effects Of The Methyl Group, Lavinel G. Ionescu

Chemistry and Chemical Biology ETDs

There are two methods commonly employed for the measurement of radiation: the ionization chambers, such as the various types of Geiger­Mliller tubes, and the scintillation counters.

Some 2-Aryl-6-Phenylindenes, 2-Aryl-3-Methyl-6-Phenylindenes, 2-Aryl-3, 4-Dihydro-6-Phenylnaphthalenes, And 2-Aryl-3, 4-Dihydro-1-Methyl-6-Phenylnaphthalenes As Liquid Scintillators: The Steric Effects Of A Methyl Group, David Webster Holty

Chemistry and Chemical Biology ETDs

Liquid Solution Scintillator Systems1. Absorption and emission spectra of organic molecules arise from energy transitions within the molecule. Quantization of energy dictates that the energy levels in molecules will be specific and characteristic distances apart. The simplest description of the electronic energy levels in a molecule starts with "ground state" and includes "excited state #1” and so forth; this simple description allows only for the electronic excitation. In practice each electronic energy level is split into sublevels by other energetic transitions in the molecule, such as vibrations and rotations (Figure la).

Potential Neoplasm Inhibitors, Andrew G. Bachmann

Master's Theses

The historical portion of this paper is designed to show the value of mustard compounds in the treatment of cancer and the methods used to take advantage of various exploit­ able variants between normal tissue and cancerous tissue.

The experimental section is an effort to evaluate and take advantage of the variant of pH.