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Corrigendum To “Polybrominated Methoxy- And Hydroxynaphthalenes” [Turkish Journal Of Chemistry 40 (2) 2016 332-346 ], Kiymet Berki̇l Akar, Osman Çakmak, Tuncay Tunç

Turkish Journal of Chemistry

This corrigendum is to address an issue regarding the manuscript’s previous publication. The authors have regrettably noticed that the incorrect version of the figure and crystal data was used in the original published version of this paper. To rectify this oversight and ensure the accuracy of the published work the correct figure and data are included for your reference.

Link to the original article: https://journals.tubitak.gov.tr/chem/vol40/iss2/11/

A Coarse-Grained Molecular Dynamics Study Of Gas Hydrate Formation And Dissociation, Meisam Adibifard

LSU Doctoral Dissertations

The study of gas hydrates has increased significantly over the last two decades because of their potential application in energy storage, production and transportation, water desalination, refrigeration, gas separation, etc. There is a significant interest in commercially developing natural gas hydrates because the energy content of methane hydrate reservoirs (MHRs) is at least twice that of all conventional fossil fuels combined. Additionally, due to the higher storage capacity of hydrates, it is proposed to sequester CO₂ in the form of CO₂ hydrate, thereby reducing the amount of greenhouse gases. Hence, hydrates offer a dual solution to two of …

Metal-Organic Frameworks For Global Environmental Challenges, Kyoungchul Park

Theses and Dissertations

Over the past few decades, there has been a demand for improving nuclear waste administration due to a significant increase in the utilization of nuclear energy. The driving force for proper nuclear waste disposal is evident when considering past nuclear catastrophes—such as Chernobyl and Fukushima—where radionuclide contamination of large bodies of water sparked public concern. In order to manage such radioactive species, the emerging areas of radionuclide sequestration, storage, separation, and sensing must be addressed in the upcoming years. This dissertation presents a potential candidate for addressing these challenges, called metal-organic frameworks (MOFs). Due to their porosity, high surface area, …

The Control And Operation Of Optical Sensors For Environmental Monitoring With Microcontrollers As Data Acquisition And Processing Systems, Zechariah Kitzhaber

Theses and Dissertations

Phytoplankton are microscopic unicellular organisms, and they are ubiquitous in marine and freshwater environments across the globe. They play a critical role in primary production, carbon fixation, and O2 production through photosynthesis. Phytoplankton comprise an abundant variety of genera and species, and the taxonomic makeup of a community can be an important indicator of environmental health. Phytoplankton are spatially and taxonomically diverse; they change in size and cellular content throughout their lifetime, and they can also alter their pigmentation in response to environmental factors, so it is important to understand the variability in size and pigmentation between individuals of the …

Alternate Conformational Trajectories In Ribosome Translocation, Jose L. Alejo, Dylan Girodat, Michael J. Hammerling, Jessica A. Willi, Michael C. Jewett, Aaron E. Engelhardt, Katarzyna P. Adamala

Chemistry & Biochemistry Faculty Publications and Presentations

Abstract

Translocation in protein synthesis entails the efficient and accurate movement of the mRNA-[tRNA]₂ substrate through the ribosome after peptide bond formation. An essential conformational change during this process is the swiveling of the small subunit head domain about two rRNA ‘hinge’ elements. Using iterative selection and molecular dynamics simulations, we derive alternate hinge elements capable of translocation in vitro and in vivo and describe their effects on the conformational trajectory of the EF-G-bound, translocating ribosome. In these alternate conformational pathways, we observe a diversity of swivel kinetics, hinge motions, three-dimensional head domain trajectories and tRNA dynamics. By finding …

Making And Breaking Bonds: Studying Intrinsic Chemistry In The Gas-Phase, Luke Metzler

Electronic Theses and Dissertations

The nature of chemical interactions can be difficult to ascertain in the condensed phase; chemistry can be observed, but with the plethora of variables such as solvation, mixes of counter-ions, and complex equilibria, the true intrinsic chemical properties of a given chemical species may be obfuscated. By conducting research in the gas-phase, many of these variables can be reduced, if not eliminated entirely, which can allow for the careful observation of the true physical phenomena driving chemical reactivity.

The research presented herein focuses on the use of ion-trapping (specifically in a linear ion trap) as a method for unveiling the …

Flora And Fauna Lexical Indicators Of Prehistoric Movement Of Yuman Peoples, Adam Ingwerson

Master's Theses

Amyloid fibrils are locally ordered protein aggregates characterized by a filamentous morphology held together by a hydrogen bonding motif known as cross-β structure whereby hydrogen bonds form between backbone amide bond moieties across separate protein segments. The most notable medical significance of amyloid fibrils is their central role in the etiology of Alzheimer’s disease, type 2 diabetes, and other human diseases. Although amyloid fibrils have been studied extensively, the mechanism of their formation is still not fully understood. X-ray crystallography is a leading experimental technique for resolving amyloid fibril structures from crystallized proteins; however, inherent limitations leave open the possibility …

Agnotology Of The E-Cigarette Industry: How The E-Cigarette Industry Continues The Tobacco Industry's Legacy Of Creating Controversy And Confusion Within The Scientific Community And The General Population, Calvin Lewis

University Honors Theses

The purpose of this paper is to determine the extent to which the e-cigarette industry follows in the footsteps of the tobacco industry's attempts to disrupt science and cause controversy. Four tactics are described that the tobacco industry uses to disrupt science: funding research that is designed to show results that support their position, criticizing and suppressing research that goes against their position, changing risk assessment and scientific research standards to fit their aims, and spreading data created by their interest groups to politicians and the nonacademic press. Evidence is found to show that both the tobacco industry and e-cigarette …

Rna Secondary Structures: Structure-Function Studies In Viral And Neurodegenerative Diseases, Caylee Cunningham

Electronic Theses and Dissertations

The studies within this dissertation highlight the importance of RNA structure and function, highlighting potential mechanisms in the pathogenesis of the SARS-CoV-2 virus and hallmarks of ALS. Specifically, the s2m, a 41-nt structure found within the hyper variable region of the 3’ UTR of the SARS-CoV-2 virus, was investigated as this element has no definitive role in viruses but its high conservation in several viral families warrants investigation. We used various biophysical techniques to determine if a palindromic sequence in the terminal loop could participate in dimerization activities, which may have implications in recombination and the longevity of the virus. …

Syntheses, Characterizations And Reactions Of Acene-2,3-Dicarbaldehydes, Glen Miller, Qian Liu

Faculty Publications

Here, we report improved syntheses, detailed characterizations and reactions of a series of acene-2,3- dicarbaldehydes including tetracene-2,3-dicarbaldehyde. DFT calculations corroborate and complement the experimental results. Tetracene-2,3-dicarbaldehyde and the benchmark organic semiconductor pentacene have isoelectronic p-systems and similar HOMO–LUMO gaps. Tetracene-2,3-dicarbaldehyde is soluble in a host of organic solvents (e.g., DMF, toluene, THF, chloroform, dichloromethane) and shows excellent photooxidative resistance in solution phases exposed to light and air. Further, it is readily sublimed from the solid-state without decomposition, and can be functionalized using different chemistries. We have demonstrated the utility of acene-2,3-dicarbaldehydes as reactants in the syntheses of novel diaryl-2,3-acenedimethanols and …

63rd Annual Rocky Mountain Conference On Magnetic Resonance

Rocky Mountain Conference on Magnetic Resonance

Final program, abstracts, and information about the 63rd annual meeting of the Rocky Mountain Conference on Magnetic Resonance, co-endorsed by the Colorado Section of the American Chemical Society and the Society for Applied Spectroscopy. Held in the Copper Conference Center, Copper Mountain, Colorado, August 4-8, 2024.

Green Synthesis Of Carbonized Chitosan-Fe3o4-Sio2 Nano-Composite For Adsorption Of Heavy Metals From Aqueous Solutions, Dalia A. Ali Eng, Rinad Galal Ali Eng.

Chemical Engineering

Water pollution with heavy metals owing to industrial and agricultural activities have become a critical dilemma to humans, plants as well as the marine environment. Therefore, it is of great importance that the carcinogenic heavy metals present in wastewater to be eliminated through designing treatment technologies that can remove multiple pollutants. A novel green magnetic nano-composite called (Carbonized Chitosan-Fe3O4-SiO2) was synthesized using Co-precipitation method to adsorb a mixture of heavy metal ions included; cobalt (Co2+), nickel (Ni2+) and copper (Cu2+) ions from aqueous solutions. The novelty of this study was the synthesis of a new

nano-composite which was green with …

Feasibility Study Of Using Energy Extracted From The Process Of Electrochemically Consumed Of Al 2024 For Powering Daily Used Electric Car, Yanuar Mohamad Marda, Rini Riastuti, Muhammad Hamka Ibrahim

Journal of Materials Exploration and Findings

Usage of green energy for transportation has become important due to the contribution of transportation activity to climate change. Electrochemical energy has been used as a source of green energy. The objective of this work is to evaluate sufficiency of energy provided by electrochemically consumed Al 2024 for supplying energy to daily used PHEV electric car. Study of previous articles, observation of typical amount of energy required, electrochemical galvanic cell experiments, and simple calculations have been conducted to determine produced energy feasibility. Electrical energy produced by consuming 340 gr of Al 2024 in galvanic cells has the total lifetime of …

Knowledge Management Of Historical Data: Ontology Development For Chemical Reactions, Quynh D. Tran, Alexander Harding Bradley, Balashanmuga Priyan Rajamohan, Jonathan E. Gordon, Van D. Tran, Kiefer Lin, Erika I. Barcelos, Laura S. Bruckman, Roger H. French

Researchers, Instructors, & Staff Scholarship

Knowledge management of the literature and historical data is critical to accelerated drug and materials discovery. Currently, literature knowledge is scattered in journal articles in various formats: diagrams, texts, plots, etc. Historical data from past experiments are saved in a number of local computers under confusing folder structures with ambiguous file names. To manage and organize historical data and knowledge, our group (SDLE) at CWRU follows FAIR (Findable, Accessible, Interoperable, Reusable) principles, which outline the best practices for data stewardship and data provenance, and ontology, a formal representation of terms and concepts and their relationships, as a tool to improve …

I. Degradable Polymers And Networks Based On Furan-Maleimide Diels-Alder Reactions Of Silyl Ether Derivatives And Maleimides, And Ii. The Michael Addition Of Amines To 1,3,5-Triacryloylhexahydro-1,3,5-Triazine (Tat) As A Synthetic Route To Novel Chelating Agents, Reyad Alkhazalah

Chemistry Theses and Dissertations

Degradable Polymers and Networks Based on Furan-Maleimide Diels-Alder Reactions of Silyl Ether Derivatives and Maleimides. I.

I. Part 1. Two groups of silyl ether monomers, A and B, were synthesized, each containing four different monomers. The monomers of group A were obtained by reacting furfuryl alcohol with four dichlorosilanes with varying siloxane spacers. The monomers of group B were obtained by reacting n-(2-hydroxyethyl)maleimide (HEMI-1c) with the same four dichlorosilanes. Each monomer from group A was individually reacted with each monomer from group B via a Diels-Alder reaction to produce a series of sixteen degradable linear polymers with a variety …

Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Applications For Metabolomics, Darcy Cochran, Robert Powers

Robert Powers Publications

Metabolomics is an interdisciplinary field that aims to study all metabolites < 1500 Da that are ubiquitously found within all organisms. Metabolomics is experiencing exponential growth and commonly relies on high-resolution mass spectrometry (HRMS). Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) is a form of HRMS that is particularly well suited for metabolomics research due to its exceptionally high resolution (10⁵–10⁶) and sensitivity with a mass accuracy in parts per billion (ppb). In this regard, FT-ICR-MS can provide valuable insights into the metabolomics analysis of complex biological systems due to unique capabilities such as the easy separation of isobaric and isomeric species, isotopic fine structure analysis, spatial resolution of metabolites in cells and tissues, and a high confidence (error) in metabolite identification. Alternatively, the large and complex data sets, long acquisition times, high cost, and limited access mainly through national mass spectrometry facilities may impede the …

Optimizing The Protein Yield Of The Collagen Mimetic Peptide: Col108, Fahmida Akter

Theses and Dissertations

Abstract

The fibril-forming collagen mimetic peptide Col108, produced in E. Coli, has shown potential for innovative biomaterial applications. However, further research is constrained by its limited yield. My study aims to enhance the experimental parameters and has successfully pinpointed rifampicin as an efficient method to boost the production of Col108.

Radiation-Tolerant Thin-Film Reference Electrodes And Potentiometric Sensors, Bingyuan Zhao, Alexander Wei

Department of Chemistry Faculty Publications

The integration of electronic sensors into single-use systems for bioprocessing is challenged by their sensitivity to sterilizing γ-irradiation. This challenge also applies to reference electrodes (REs), whose potentials may be destabilized upon ionization and drift over time. Here we evaluate the performance of thin-film Ag/AgCl REs over a two-month window following γ-ray sterilization using a 60Co source. γ-REs display a characteristic voltage decay function ascribed to the dissipation of radiation-induced charge defects, and exhibit long-term potentiometric stability when stored in phosphate-buffered saline (PBS) with a 95% confidence interval of 4 mV over 60 days. γ-REs have a mean insensitivity (inertness) …

Stimuli-Responsive Phosphate Hydrogel: A Study On Swelling Behavior, Mechanical Properties, And Application In Expansion Microscopy, Yokly Leng, Collin N. Britten, Fatema Tarannum, Kayla Foley, Christopher Billings, Yingtao Liu, Keisha B. Walters

Chemical Engineering Faculty Publications and Presentations

Phosphorus-based stimuli-responsive hydrogels have potential in a wide range of applications due to their ionizable phosphorus groups, biocompatibility, and tunable swelling capacity utilizing hydrogel design parameters and external stimuli. In this study, poly(2-methacryloyloxyethyl phosphate) (PMOEP) hydrogels were synthesized via aqueous activators regenerated by electron transfer atomic transfer radical polymerization using ascorbic acid as the reducing agent. Swelling and deswelling behaviors of PMOEP hydrogels were examined in different salt solutions, pH conditions, and temperatures. The degree of swelling in salt solutions followed CaCl₂ < MgCl₂ < KCl < NaCl with a decrease in swelling rate at higher concentrations until reaching a saturation point. In water, the degree of swelling increased significantly around neutral pH and remained constant at basic pH values. The effects of polymerization conditions, including pH, temperature (30, 40, 50 °C), and MOEP concentration (40, 50, 60% v/v MOEP/H₂O), on the hydrogel swelling behavior in various salt solutions were also investigated. PMOEP hydrogels …

Elevating Commodity Polymers To Advanced Applications In Polymer Photonics And Polymer-Derived Porous Materials, Mark Robertson

Dissertations

Since the inception of synthetic polymers, polymer-derived materials have permeated into essentially all aspects of our daily lives. The most commonly thought of examples of polymer materials involve single-use, disposable products to increase shelf lives of perishable items, act as personal protective equipment, or provide some degree of convenience for the consumer. However, as we have furthered our understanding of polymer chemistry and polymer physics to develop increasingly sophisticated polymer systems, polymer materials have been employed in incredibly advanced applications. These include solid electrolytes for energy storage, matrices for aerospace grade carbon fiber-reinforced composites, membranes for liquid and gas separations, …

Structure-Function Relationships In Neurodegenerative And Infectious Diseases: Biophysical Characterization Of Rna Secondary Structures By Computational Techniques, Kendy Guarinoni

Electronic Theses and Dissertations

The research described in this dissertation focuses on the investigation of the structure and dynamics of regions of RNA implicated in two diseases: COVID-19 and amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD). Both studies sought to create experimentally corroborated models that were used to characterize the structure and dynamics of the C9orf72 repeat expansion and the s2m region in coronaviruses, respectively and provided the foundation for future work. In our work involving the s2m region of SARS-CoV-2, the virus responsible for COVID-19, we determined that the homology modeling approach commonly used to derive atomistic structures when no coordinates are available yields a …

Performance And Enhanced Efficiency Induced By Cold Plasma On Sapo-34 Membranes For Co2 And Ch4 Mixtures, Fnu Gorky, Vashanti Storr, Grace Jones, Apolo Nambo, Jacek B. Jasinski, Maria L. Carreon

Chemical Engineering Faculty Publications and Presentations

In this study, we investigate the influence of cold-plasma-induced enhanced performance and efficiency of SAPO-34 membranes in the separation of CO₂ and CH₄ mixtures. Placing the herein presented research in a broader context, we aim to address the question of whether cold plasma can significantly impact the membrane performance. We subjected SAPO-34 membranes to plasma mild disturbances and analyzed their performance in separating CO₂ and CH₄. Our findings reveal a notable enhancement in membrane efficiency and sustained performance when exposed to cold plasma. The pulsed plasma separation displayed improved structural integrity, and the experimental results …

Studies Of Exotic Electronic, Optical, And Electrochemical Properties In Nanoparticle Assembly And Graphene, Jay Min Lim

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

It is well known that exotic properties and phenomena emerge as structural dimensions shrink to nanoscales. We self-assembled one-dimensional chains of gold nanoparticles in solution and quantified the growth process by monitoring the redshift of localized surface plasmon resonance (LSPR). Curiously, the redshift stopped while the chains continued to rearrange as manifested by gradual reduction in the LSPR peak. Using electromagnetic simulations, we quantitatively explained the phenomena as a rapid “addition-polymerization” followed by a sharp transition to “condensation-process.” Next, recognizing the significant electric field enhancement in the interparticle gap, a photoluminescent-active Eu³⁺ ion was used to probe Surface-Enhanced Photoluminescence …

Understanding And Tuning Magnetism In Van Der Waals-Type Metal Thiophosphates, Rabindra Basnet, Jin Hu

Physics Faculty Publications and Presentations

Over the past two decades, significant progress in two-dimensional (2D) materials has invigorated research in condensed matter and material physics in low dimensions. While traditionally studied in three-dimensional systems, magnetism has now been extended to the 2D realm. Recent breakthroughs in 2D magnetism have attracted substantial interest from the scientific community, owing to the stable magnetic order achievable in atomically thin layers of the van der Waals (vdW)-type layered magnetic materials. These advances offer an exciting platform for investigating related phenomena in low dimensions and hold promise for spintronic applications. Consequently, vdW magnetic materials with tunable magnetism have attracted significant …

Evolution Mechanism Of Organic Macromolecular Structure During Lignite Pyrolysis, Ying Shi, Yanming Zhu, Zhenjiang You, Wu Li, Yang Wang, Yu Song

Research outputs 2022 to 2026

Understanding the mechanisms governing coal pyrolysis reactions, particularly in relation to the coal macromolecular structure, is crucial for improving energy efficiency and facilitating the transition of coal into a clean energy source. This study employs cutting-edge techniques, such as High-Resolution Transmission Electron Microscopy (HRTEM) and Thermogravimetric Analysis coupled with Fourier Transform Infrared Spectroscopy and Mass Spectrometry (TG–FTIR–MS), to analyze lignite and its residual solid samples subjected to pyrolysis across a range of temperatures from 300 °C to 1100 °C. The variational characteristics of the macromolecular structure during coal pyrolysis are examined. Utilizing molecular dynamics simulations, we analyze the evolution mechanism …

Phthalocyanine-Enabled Technologies For Water Treatment And Disinfection Strategies, Hooralain Bushnaq, Catherine Munro, Sisi Pu, Amir Razmjou, Masoumeh Zargar, Giovanni Palmisano, Srinivas Mettu, Ludovic F. Dumée

Research outputs 2022 to 2026

Water treatment and disinfection are critical factors in ensuring a safe and sustainable water supply. Phthalocyanines (Pcs), a class of versatile and robust organic compounds, have garnered significant attention for their application in various water treatment processes. This review paper offers a groundbreaking investigation of Pc-enabled technologies within the domain of water treatment applications. The core aim of this review is to meticulously analyze the chemical and optical properties of Pcs, elucidate their photosensitization mechanism and establish the crucial connection between their chemical structure and photodynamic efficacy. The various modes of Pcs application in water treatment processes - whether in …

Antimicrobial And Chemical Characterization Of Cold Atmospheric-Pressure Plasmas, Dalton Albert Miller

Boise State University Theses and Dissertations

Microbial contamination of food processing facilities is a major cause of human disease and economic loss. There are approximately 48,000,000 cases of foodborne illness in the United States annually, leading to 128,000 hospitalizations and 1,300 deaths. The total economic damages are estimated at $36 billion each year, including productive hours, medical expenses, and the disposal of contaminated foodstuffs. Current methods to reduce contamination on food processing surfaces utilize steam or concentrated chemicals (hydrogen peroxide, hypochlorite, strong acids, strong bases) that are hazardous to workers and required large volumes of water to remove prior to resuming contact with food. Ongoing outbreaks …

Modeling Study Of Si3N4 Waveguides On A Sapphire Platform For Photonic Integration Applications, Diandian Zhang, Shui-Qing Yu, Gregory J. Salamo, Richard A. Soref, Wei Du

Electrical Engineering and Computer Science Faculty Publications and Presentations

Sapphire has various applications in photonics due to its broadband transparency, high-contrast index, and chemical and physical stability. Photonics integration on the sapphire platform has been proposed, along with potentially high-performance lasers made of group III–V materials. In parallel with developing active devices for photonics integration applications, in this work, silicon nitride optical waveguides on a sapphire substrate were analyzed using the commercial software Comsol Multiphysics in a spectral window of 800~2400 nm, covering the operating wavelengths of III–V lasers, which could be monolithically or hybridly integrated on the same substrate. A high confinement factor of ~90% near the single-mode …

Synthesis And Characterization Of Medicinally Privileged Aza Heterocycles, Nneoma James

Theses and Dissertations

Four-membered cyclic amides, commonly known as β-lactams, have played a crucial role in drug discovery research since its discovery by Alexander Fleming in 1928 from Penicillium notatum. The β-lactam antibiotics are broadly effective against several bacterial infections through acylating the transpeptidase involved in cross-linking peptides to form peptidoglycan or periplasmic murein, which is a fundamental constituent of the bacterial cell wall for both the gram-positive (ten or more layers) and gram-negative (one or two layers) bacteria. Although for more than eight decades, β-lactams have been recognized as antibiotics, later, other medicinal activities of β-lactam derivatives have been reported, including lowering …

Settingsorder Article Reprints Open Accessarticle A Model To Account For The Effects Of Load Ratio And Hydrogen Pressure On The Fatigue Crack Growth Behavior Of Pressure Vessel Steels, Ashok Saxena, Kip O. Findley

Mechanical Engineering Faculty Publications and Presentations

A phenomenological model for estimating the effects of load ratio R and hydrogen pressure P_H2 on the hydrogen-assisted fatigue crack growth rate (HA-FCGR) behavior in the transient and steady-state regimes of pressure vessel steels is described. The "transient regime" is identified with crack growth within a severely embrittled zone of intense plasticity at the crack tip. The "steady-state" behavior is associated with the crack growing into a region of comparatively lower hydrogen concentration located further away from the crack tip. The model treats the effects of R and P_H2 as being functionally separable. In the transient …