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Articles 1081 - 1110 of 39279
Full-Text Articles in Entire DC Network
Dna Methylation Correlates With Transcriptional Noise In Response To Elevated Pco2 In The Eastern Oyster (Crassostrea Virginica), Yaamini R. Venkataraman, Ariana S. Huffmyer, Samuel J. White, Alan Downey-Wall, Jill Ashey, Danielle M. Becker, Zachary Bengtsson, Hollie M. Putnam, Emma Strand, Javier A. Rodríguez-Casariego, Shelly A. Wanamaker, Katie E. Lotterhos, Steven B. Roberts
Dna Methylation Correlates With Transcriptional Noise In Response To Elevated Pco2 In The Eastern Oyster (Crassostrea Virginica), Yaamini R. Venkataraman, Ariana S. Huffmyer, Samuel J. White, Alan Downey-Wall, Jill Ashey, Danielle M. Becker, Zachary Bengtsson, Hollie M. Putnam, Emma Strand, Javier A. Rodríguez-Casariego, Shelly A. Wanamaker, Katie E. Lotterhos, Steven B. Roberts
Biology
Ocean acidification significantly affects marine calcifiers like oysters, warranting the study of molecular mechanisms like DNA methylation that contribute to adaptive plasticity in response to environmental change. However, a consensus has not been reached on the extent to which methylation modules gene expression, and in turn plasticity, in marine invertebrates. In this study, we investigated the impact of pCO2 on gene expression and DNA methylation in the eastern oyster, Crassostrea virginica. After a 30-day exposure to control (572 ppm) or elevated pCO2 (2827 ppm), whole-genome bisulfite sequencing (WGBS) and RNA-seq data were generated from adult female gonad tissue …
Genetic Entropy: A Critical Examination, Sarah Hunter
Genetic Entropy: A Critical Examination, Sarah Hunter
Science, Faith, and Origins
Genetic entropy is a hypothesis proposing that genomes deteriorate over time due to the gradual accumulation of slightly harmful mutations that natural selection cannot effectively remove. This paper explores the scientific debate surrounding this claim by examining differing perspectives on the theory of genetic entropy. Proponents of genetic entropy, such as John Sanford, argue that most mutations are deleterious and fall within a “near-neutral” range, allowing them to accumulate since their effects are too small for natural selection to detect. Evidence to support this claim includes Robert Carter and John Sanford’s research on the deterioration of the H1N1 viral genome …
Science, Sand, And Faith: Exploring Competing Explanations Of Coconino Sandstone, Emily Schneider
Science, Sand, And Faith: Exploring Competing Explanations Of Coconino Sandstone, Emily Schneider
Science, Faith, and Origins
The Coconino Sandstone, a Permian rock layer found in the western United States, is a topic of debate among standard geologists and flood geologists. The conventional geological interpretation claims the sandstone is an eolian deposit, meaning the sediments were deposited by wind (McKee, 1979; Selley, 1968). In their view, key elements of the sandstone, like the cross-stratified beds, high degree of frosting, and the animal trackways, confirm the Coconino’s similarity to modern eolian dunes (McKee, 1979). As this rock layer is sandwiched between layers typically interpreted by flood geologists as being deposited during the flood, the idea that the Coconino …
Targeting Ribosome Biogenesis In Cic-Dux4 Sarcoma Treatment By Using Rna Polymerase 1 Inhibitors, Hema Sri Kambala
Targeting Ribosome Biogenesis In Cic-Dux4 Sarcoma Treatment By Using Rna Polymerase 1 Inhibitors, Hema Sri Kambala
Theses
CIC-DUX4 sarcoma (CDS) is a rare, aggressive round-cell tumor that primarily affects children and young adults and is associated with poor clinical outcomes. Current treatments borrow from Ewing sarcoma regimens but offer limited benefit, underscoring the need for targeted therapeutic strategies. Transcriptomic analysis of CDS cell lines revealed a striking overrepresentation of ribosome biogenesis genes, indicating that CDS relies heavily on hyperactive RNA Polymerase I (Pol I)–driven rRNA synthesis. To evaluate this vulnerability, the Pol I inhibitors CX-5461 and BMH-21 were tested across multiple functional assays, including rRNA transcription, proliferation, migration, and 3-dimensional spheroid growth. Both inhibitors reduced rRNA synthesis …
Getting To The Root Of The Problem: A Comparison Of Rhizome Extracts For The Control Of Cogongrass (Imperata Cylindrica), Mia Martin-Fuller, Elizabeth Esser, Ashley Schulz
Getting To The Root Of The Problem: A Comparison Of Rhizome Extracts For The Control Of Cogongrass (Imperata Cylindrica), Mia Martin-Fuller, Elizabeth Esser, Ashley Schulz
Annual Student Research Poster Session
Cogongrass is a perennial grass that was introduced to the southeastern United States in 1912 and has since spread aggressively throughout the region. It is very resilient to disturbances as it can propagate through seed and rhizome, which makes it extremely difficult to control. Most efforts to control cogongrass populations have used synthetic herbicides, though burning and tilling have also been explored. A new method applies autotoxic leachates produced by the target plant to the plant for control. Although this method of control has been demonstrated in giant salvinia (Salvinia molesta), researchers have not yet identified the methods to control …
Light Stress And Leaf Characteristics In Prairie Fleabane In A Limestone Quarry, Guoqing Evelyn Tuohy
Light Stress And Leaf Characteristics In Prairie Fleabane In A Limestone Quarry, Guoqing Evelyn Tuohy
Annual Student Research Poster Session
DePauw’s nature park was an active limestone quarry for 60 years and has been going through primary succession since 1977. This harsh and disturbed environment can make it difficult for plants to survive. In this study, I aimed to investigate the Erigeron strigosus (Prairie Fleabane), a native plant commonly found in open, disturbed areas. I wanted to examine how the amount of light affected leaf traits in Erigeron strigosus because I had observed and hypothesized that in sunny areas, the leaf orientation changed, and the size of the leaves was smaller, and in shady areas, the leaves would be in …
Investigating The Effect Of Gene Ncu07872 Deletion On Spore Killing By Neurospora Sk-3, Allison Rimmey
Investigating The Effect Of Gene Ncu07872 Deletion On Spore Killing By Neurospora Sk-3, Allison Rimmey
Senior Theses – Biological Sciences
The selfish genetic element Spore killer-3 (Sk-3) is found in some Neurospora fungi. Sk-3 is considered selfish because it has evolved the capacity to bias its transmission to the next generation through spore killing. The mechanism of spore killing requires at least two genes, a gene that produces a resistance protein (an antidote) and a gene that produces a killer protein (a poison). The Sk-3 genetic element is millions of base pairs long and contains hundreds of genes. Although the antidote gene has been identified, the identity of the poison gene has remained elusive. Previous research has identified a DNA …
Memories Of Trees Past: Coexistence Implications Of Legacy Conspecific Density Dependence, Lukas J. Magee, Daniel J.B. Smith, David Bauman, Po-Ju Ke, Helene C. Muller-Laudau, Kristina J. Anderson-Teixeira, Jessica Shue, David A. Orwig, Sean M. Mcmahon, Stephanie Bohlman, Raelene M. Crandall, Ben Weinstein, Sergio Marconi, Jeremy W. Lichstein, James F. Gillooly, Robert Bagchi, Joseph A. Lamanna, Daniel J. Johnson
Memories Of Trees Past: Coexistence Implications Of Legacy Conspecific Density Dependence, Lukas J. Magee, Daniel J.B. Smith, David Bauman, Po-Ju Ke, Helene C. Muller-Laudau, Kristina J. Anderson-Teixeira, Jessica Shue, David A. Orwig, Sean M. Mcmahon, Stephanie Bohlman, Raelene M. Crandall, Ben Weinstein, Sergio Marconi, Jeremy W. Lichstein, James F. Gillooly, Robert Bagchi, Joseph A. Lamanna, Daniel J. Johnson
Biological Sciences Faculty Research and Publications
The Janzen-Connell Hypothesis posits that plant species diversity is maintained by a reduction in seedling survival near living conspecific trees relative to heterospecifics–known as negative conspecific density dependence (CDD). CDD facilitates coexistence if stronger than heterospecific density dependence (HDD). However, whether and how long CDD persists after trees die is unknown. In a three-year study across three forests, we monitored seedling survival near living and dead trees, both conspecific and heterospecific, across a seven-year chrono-sequence since tree death. CDD persisted for at least 5 years after tree death (‘legacy CDD’), and most species showed stronger CDD relative to HDD through …
(Si15-107) Mathematical Modeling Of Cancer Dynamics Stability Analysis Of Post Therapy Protection, Rajendran Swetha, Tharmalingam Gunasekar, Kamalendra Kumar, Krishnasamy Sakthivel
(Si15-107) Mathematical Modeling Of Cancer Dynamics Stability Analysis Of Post Therapy Protection, Rajendran Swetha, Tharmalingam Gunasekar, Kamalendra Kumar, Krishnasamy Sakthivel
Applications and Applied Mathematics: An International Journal (AAM)
The study of PSITPS mathematical model is developed to analyze cancer dynamics, focusing on post-therapy protection. The model’s solution is rigorously examined for boundedness and positivity of solutions. Equilibrium points are identified, and numerical methods are employed to study stability. Simulations using accurate cancer data demonstrate the effectiveness of post-treatment protection in controlling cancer spread and minimizing recurrence. Stability analysis confirms the model’s predictive capability, offering valuable insights into long-term patient outcomes. The results highlight the importance of continuous post-treatment care in improving survival rates and reducing disease prevalence. This study provides a framework for optimizing cancer treatment strategies by …
Cul3 Postnatal Homozygous Deletion In Forebrain Results In Behavioral Differences, Prathibha Sekar, Qiang‐Qiang Xia, Alex C. Stokes, Feiyu Quan, Jeffrey Singer, Craig M. Powell
Cul3 Postnatal Homozygous Deletion In Forebrain Results In Behavioral Differences, Prathibha Sekar, Qiang‐Qiang Xia, Alex C. Stokes, Feiyu Quan, Jeffrey Singer, Craig M. Powell
Biology Faculty Publications and Presentations
Large-scale human genetic studies implicate multiple genes that regulate protein ubiquitination in autism spectrum disorder (ASD). De novo loss-of-function mutations in the gene CULLIN3 (CUL3) are implicated in autism and intellectual disability (ID). CUL3 is an essential component of an E3 ubiquitin ligase complex required for ubiquitination of substrates, often a signal for proteasomal degradation. Homozygous deletion of Cul3 is embryonically lethal. Recent studies show heterozygous deletion of Cul3 results in phenotypes with some face validity for autism in constitutive and conditional Cul3 heterozygotes. To understand the function of Cul3 in late postnatal development and function in the brain, we …
(Si15-121) Analyzing Seitr Tuberculosis Transmission Model Using Caputo–Fabrizio Fractional Derivative With Diverse Contact Rates, S. S. Sumaiya Banu, T. Gunasekar, S. Manikandan, Kamalendra Kumar, M. Suba
(Si15-121) Analyzing Seitr Tuberculosis Transmission Model Using Caputo–Fabrizio Fractional Derivative With Diverse Contact Rates, S. S. Sumaiya Banu, T. Gunasekar, S. Manikandan, Kamalendra Kumar, M. Suba
Applications and Applied Mathematics: An International Journal (AAM)
In the modern age, tuberculosis remains a pressing global health concern. Our study introduces and evaluates the SEITR pandemic TB transmission model, dividing the population into five compartments to explore distinct characteristics relevant to our investigation. Additionally, we delve into the application of fractional calculus. Through the Laplace transform method, we derive series solutions for all compartments, ensuring their existence and uniqueness. We also investigate the reproduction number of the tuberculosis epidemic model, examining how varying contact rates impact disease spread. We apply the predictor-corrector method for the Caputo-Fabrizio fractional derivative to verify the accuracy of our approach. This accurately …
Assessing Expected Cover Of Invasive Flora Species Near Corridor Features By Distance, Joshua G. Logan
Assessing Expected Cover Of Invasive Flora Species Near Corridor Features By Distance, Joshua G. Logan
Theses
Fragmentation of landscapes has been a growing topic of interest within scientific literature over the past several decades, as the way we as humans affect our planet becomes more apparent as the years go on. As humans, we have shaped the land and what it contains in immeasurable ways, erasing or forever altering entire natural ecosystems. Chief among the drivers altering these ecosystems is the fragmentation of landscapes, which can have all kinds of effects on natural ecosystems, from limiting nutrient transport to providing easier access for invasives to permeate throughout a landscape. Corridors are significant areas of interest regarding …
Hooks For Four-Dimensional Ecology Education (4dee) Teaching With Differing Audiences Of Nonmajors, Sara E. Scanga, Vikki L. Rodgers, Loren B. Byrne, Justin R. St. Juliana, Jon M. Honea, Erica S. Tietjen, George Middendorf
Hooks For Four-Dimensional Ecology Education (4dee) Teaching With Differing Audiences Of Nonmajors, Sara E. Scanga, Vikki L. Rodgers, Loren B. Byrne, Justin R. St. Juliana, Jon M. Honea, Erica S. Tietjen, George Middendorf
Arts & Sciences Faculty Publications
Nonmajors (i.e., undergraduate students not majoring in the natural sciences) constitute a majority of United States college graduates and are a large potential audience for courses with ecology content. However, nonmajors may be unmotivated to learn about ecology because they perceive it to be uninteresting and irrelevant to their everyday lives or career goals. Although the Four-Dimensional Ecology Education (4DEE) framework can be adapted for nonmajors courses as a starting point to improve student engagement, we suggest that nonmajors ecology instructors also use ecology hooks as effective gateways to 4DEE that will motivate and deepen student learning. Selecting and developing …
Hcmv Infection Of Terminally Differentiated Neurons Disrupts Microtubule Organization, Resulting In Neurite Retraction, Jacob W. Adelman, Andrew T. Sukowaty, Kaitlyn J. Partridge, Jessica E. Gawrys, Allison Akins, Scott S. Terhune, Allison D. Ebert
Hcmv Infection Of Terminally Differentiated Neurons Disrupts Microtubule Organization, Resulting In Neurite Retraction, Jacob W. Adelman, Andrew T. Sukowaty, Kaitlyn J. Partridge, Jessica E. Gawrys, Allison Akins, Scott S. Terhune, Allison D. Ebert
Biological Sciences Faculty Research and Publications
Human cytomegalovirus (HCMV) is a prolific human herpesvirus that infects most individuals by adulthood. While typically asymptomatic in adults, congenital infection can induce serious neurological symptoms, including hearing loss, visual deficits, cognitive impairment, and microcephaly in 10%–15% of cases. HCMV has been shown to infect most neural cells, with our group recently demonstrating this capacity in stem cell-derived forebrain neurons. Infection of neurons induces deleterious effects on calcium dynamics and electrophysiological function paired with gross restructuring of neuronal morphology. Here, we utilize an induced pluripotent stem cell-derived model of the human forebrain to demonstrate how HCMV infection induces syncytia, drives …
Does Increasing Canopy Liana Density Decrease The Tropical Forest Carbon Sink?, Stefan A. Schnitzer, David M. Defilippis
Does Increasing Canopy Liana Density Decrease The Tropical Forest Carbon Sink?, Stefan A. Schnitzer, David M. Defilippis
Biological Sciences Faculty Research and Publications
The ongoing decline in the American tropical forest carbon sink has serious ramifications for atmospheric carbon levels and global climate change. Increasing liana abundance may explain the decaying carbon sink because lianas reduce canopy tree growth and survival, which limits forest carbon storage. However, canopy lianas, not solely understory lianas, would have to be increasing for this hypothesis to be credible because canopy lianas compete especially intensely with canopy trees. We examined the change in canopy lianas over 10 years on Barro Colorado Island (BCI), Panama to test two main hypotheses. (1) Canopy lianas are increasing on BCI. (2) Increasing …
Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons
Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons
Theses and Dissertations
Humans have complex signaling pathways that allow them to store and expend energy based on nutritional quality and availability. Inter-organ signaling is used to communicate nutrient availability between organs based on nutritional needs and the rate of cellular division. Our main overarching question is to investigate how fat-derived signals affect adipocyte morphology and the maintenance of stem cells in the ovary. While signaling pathways, like insulin and mTOR, and some adipokines that are involved in inter-organ nutrient sensing have been identified, the exact nutrient reliant mechanisms of stem cell maintenance are not completely understood. Using Drosophila melanogaster as a model, …
The Science Of Sound: Studying The Cognitive, Emotional, And Physiological Effects Of Frequency, Genre, And Music, Jett Yarborough
The Science Of Sound: Studying The Cognitive, Emotional, And Physiological Effects Of Frequency, Genre, And Music, Jett Yarborough
Senior Honors Theses
Music influences emotion, physiology, and cognition, yet little is known about how the frequency it is tuned to affects these influences. Prior research has shown that music tuned to 432 Hz can reduce stress, lower blood pressure, and improve sleep. My colleagues and I conducted two studies to investigate this. Our research found that music tuned to 432 Hz promotes a significant increase in memory retention and induces a state of focus and relaxation. These results suggest that shifting from the standard tuning frequency of 440 Hz to 432 Hz could have a profoundly positive impact on our daily lives. …
Introducing Patient-Centered Outcomes To Preceptors In Caate-Approved Athletic Training Programs, K. Judge
Introducing Patient-Centered Outcomes To Preceptors In Caate-Approved Athletic Training Programs, K. Judge
Clinical Practice in Athletic Training
The 2020 standards set by the Commission on Accreditation of Athletic Training Education (CAATE) now require the incorporation of the International Classification of Function and Patient-Centered Outcomes into professional practice. These standards can be introduced initially through simulation, but to develop a competent and culturally aware professional, outcome measures should be completed during clinical experiences under the guidance of approved preceptors. As this is a relatively new standard, many preceptors did not receive this as part of their education and may be uncomfortable integrating outcomes into their practice. This lack of integration can negatively affect the learning opportunities of athletic …
Incorporating Balance Training Into Ankle Sprain Injury Prevention Programs: An Evidence-To-Practice Review, David Tomchuk, Jacob Meyer, Kyle Schneider, Ben Fox
Incorporating Balance Training Into Ankle Sprain Injury Prevention Programs: An Evidence-To-Practice Review, David Tomchuk, Jacob Meyer, Kyle Schneider, Ben Fox
Clinical Practice in Athletic Training
Ankle sprains are among the most common injuries in sports and non-sporting activities. For patients, ankle sprains can result in multiple short and long-term hardships, such as financial burdens of evaluation and treatment, absenteeism from sport and physical activity, and diminished ankle and lower extremity function. However, athletic trainers and other stakeholders are also impacted by administrative and time burdens in caring for ankle sprains and how ankle sprains affect team dynamics and performance. The 2022 guiding systematic review evaluated the effectiveness of incorporating preventive balance training exercises on the incidence of ankle sprains in soccer athletes. The search performed …
Psychological And Psychosocial Effects Of Contemplative Practices In The Athletic Population: A Systematic Review, Victoria Baker, Emily Duckett, Alison Gardiner-Shires, Lindsey Keenan
Psychological And Psychosocial Effects Of Contemplative Practices In The Athletic Population: A Systematic Review, Victoria Baker, Emily Duckett, Alison Gardiner-Shires, Lindsey Keenan
Clinical Practice in Athletic Training
Mental health concerns in athletes are becoming a primary focus for institutions, companies, coaches, and more. An athlete carries an abundant load of stressors due to their lifestyle. The stressors can negatively impact an athlete by producing anxiety, depression, insomnia, and other mental health concerns. Previous studies have found a connection between the use of contemplative practices on psychological and psychosocial effects in athletes, creating an opportunity to evaluate the research of contemplative practices in the athletic population. 5, 7, 8, 13-16 A systematic review was conducted using nine electronic databases. Seven studies were included in this review, each assessing …
Use Of An Electronic Dynamometer Following Pitching To Identify Fatigue In Softball Pitchers, Bethany L. Hansberger, Peter Lisman
Use Of An Electronic Dynamometer Following Pitching To Identify Fatigue In Softball Pitchers, Bethany L. Hansberger, Peter Lisman
Clinical Practice in Athletic Training
This study used a case-series design to collect in-game fatigue measures for collegiate softball pitchers immediately after pitching during the competitive season. Five softball pitchers (age = 19.8 ± 1.5 years; height = 169.9±6.1 cm; body mass = 79.1±22.6 kg) from one Division I program were recruited. Isometric internal and external rotation, scaption, and grip strength measures were collected using an electronic dynamometer at the beginning and conclusion of the fall non-traditional season, and at the beginning of preseason in January. Strength measures were also obtained during the competitive season at the conclusion of pitching in a game and compared …
Concurrent Acl And Medial/Lateral Meniscal Repair In A Collegiate Soccer Player: Disablement Model Case Study, Rebecca L. Perry, Angelica Alicea, Jeanette Welch, Carl White, Emily E. Hildebrand, Peter Lisman
Concurrent Acl And Medial/Lateral Meniscal Repair In A Collegiate Soccer Player: Disablement Model Case Study, Rebecca L. Perry, Angelica Alicea, Jeanette Welch, Carl White, Emily E. Hildebrand, Peter Lisman
Clinical Practice in Athletic Training
This case examines a 19-year-old female Division I collegiate soccer player who underwent anterior cruciate ligament (ACL) reconstruction with medial and lateral meniscal repairs. Though meniscal tears often occur in conjunction with ACL injury, incidence of concurrent medial and lateral tears with presence of a displaced bucket-handle lesion is rare. This patient attempted to tackle an oncoming opponent in which contact caused forceful trunk rotation away from her planted right foot. Sideline evaluation revealed medial and posterior knee pain with active knee range of motion deficits. Further evaluation revealed apprehension and muscle guarding during Lachman’s, anterior drawer, and valgus stress …
Suturing Education For Athletic Trainers: An Evidence-To-Practice Review, Morgan K. Webb, Brett T. Heim, Allyson E. Ritchey, Kenya Moore, Zachary K. Winkelmann
Suturing Education For Athletic Trainers: An Evidence-To-Practice Review, Morgan K. Webb, Brett T. Heim, Allyson E. Ritchey, Kenya Moore, Zachary K. Winkelmann
Clinical Practice in Athletic Training
Teaching suturing skills to medical students is a critical component of their education. Implementing suturing into a comprehensive framework is developed from how professors teach the skill. Suturing is a required skill by the General Medical Council that all medical students must have, and how it is being introduced to new students is changing. This review aimed to summarize different educational interventions and determine the most efficient and cost-effective way to teach future suturing skills. The original systematic review included 25 articles in the final data synthesis. Fourteen studies were randomized control trials, six were quasi-experimental, and five were observational. …
Impact Of A Focused Best Practice Workshop On Athletic Trainer Confidence, Jaclyn B. Arduini, Jennifer L. Volberding, Zachary A. Murray
Impact Of A Focused Best Practice Workshop On Athletic Trainer Confidence, Jaclyn B. Arduini, Jennifer L. Volberding, Zachary A. Murray
Clinical Practice in Athletic Training
Athletic trainers are required to be proficient in emergency management skills, without review these skills may decay creating a potentially dangerous knowledge gap. Confidence measures of emergency management skills were taken before and after a workshop to determine if they changed due to the review of material. All 11 confidence measures increased post workshop, seven significantly, including rectal temperature, hemostatic agents, external hemostatic modalities, in-line stabilization, measurement and application of a cervical collar, football and other equipment removal. ATs should aim to incorporate emergency management review into continuing education choices.
Neuromuscular Deficits Following An Isolated Pcl Tear In A Collegiate Lacrosse Player: A Case Study, Mckenna G. Witlin, Erin R. Mcmullan, Courtney M. Meyer, Amy L. Fraley
Neuromuscular Deficits Following An Isolated Pcl Tear In A Collegiate Lacrosse Player: A Case Study, Mckenna G. Witlin, Erin R. Mcmullan, Courtney M. Meyer, Amy L. Fraley
Clinical Practice in Athletic Training
This disablement model case study outlines a 21-year-old female collegiate lacrosse player attending a United States service academy who presented with a unique neuromuscular deficit following a conservative grade II PCL tear rehabilitation. Nearing the end of her rehabilitation protocol, she noticed difficulty with toe-off while running; however, she did not report to the athletic trainer due to the institution’s holiday break proximity. An unexpected transfer of care occurred when the patient returned after the holidays, and she was cleared for full participation upon return. Several days after the patient was cleared, she reported her ankle feeling “stuck.” Upon evaluation, …
Improving The Discussion Of Suicide Prevention: A Quality Improvement Project, Chelsea Reynolds, Alyssa Zeitouni, Kathryn Stephenson
Improving The Discussion Of Suicide Prevention: A Quality Improvement Project, Chelsea Reynolds, Alyssa Zeitouni, Kathryn Stephenson
Clinical Practice in Athletic Training
Suicide is currently the second leading cause of death among adolescents in the United States and the third leading cause of death in this age group worldwide.1,2 Suicide prevention is understandably a growing focus in pediatrics. Currently, at the Children’s Hospital Outpatient Clinic, that is staffed by pediatric resident physicians, suicidal ideation is screened for using a PHQ-9 screen. However, at the time this study was initiated and completed, the TEEN screen was utilized. After the screening is performed, regardless of type, it is up to the provider to address these findings in a safe and effective manner. The goal …
Examining Burnout Among Athletic Trainers Employed In The College And Secondary School Settings, Stephanie M. Singe, Dayna Liu, Alexandrya Cairns
Examining Burnout Among Athletic Trainers Employed In The College And Secondary School Settings, Stephanie M. Singe, Dayna Liu, Alexandrya Cairns
Clinical Practice in Athletic Training
Burnout continues to be an important concern for athletic trainers working traditional employment settings. The purpose of this study was to compare the secondary school and collegiate settings in relation to burnout. Both secondary school and collegiate athletic trainers participated in a self-reported, online cross-sectional design (Qualtrics) to collect data on their experiences with burnout. Data collection occurred during the second week of October 2023 and ceased during the early weeks of November. Collegiate athletic trainers reported moderate burnout overall (54.56 ±15.89) on the CBI whereas secondary school athletic trainers reported low burnout overall (46.67 ±16.57). On the personal-related burnout …
Unveiling Caulocovert: Conserved Phage And Gene Transfer Agent In Caulobacter, Talia Neco
Unveiling Caulocovert: Conserved Phage And Gene Transfer Agent In Caulobacter, Talia Neco
Theses and Dissertations
Bacteriophage play an important role in bacterial evolution, population control, and horizontal gene transfer within microbial ecosystems. This study focuses on the discovery and characterization of Caulocovert, an active bacteriophage identified in multiple Caulobacter strains. Using genome annotation tools such as Artemis and Mauve, we identified multiple key phage genes, including the major capsid protein, head-tail connector, portal protein, and major tail protein. These phage genes are present in CB13 and several other strains, such as C. vibriodies CB15 and CB2, C. segnis CBR1, Caulobacter sp. FWC26, and the distantly related Caulobacter sp. D5 strain. The location of these genes …
Conservative Management Of Athletic Pubalgia In A Collegiate Beach Volleyball Athlete: A Case Study, Sydney F. Hendrick, Amy L. Fraley, Madison V. Kefferstan, Zachary K. Winkelmann
Conservative Management Of Athletic Pubalgia In A Collegiate Beach Volleyball Athlete: A Case Study, Sydney F. Hendrick, Amy L. Fraley, Madison V. Kefferstan, Zachary K. Winkelmann
Clinical Practice in Athletic Training
A 24-year-old female collegiate beach volleyball athlete experienced sharp pain in the pubis symphysis region after turning and running to reach a ball hit over her right shoulder. The patient was unable to move her lower extremities without extreme pain and required help off the court. She was referred to the student health center, where no initial imaging was performed. Differential diagnoses included osteitis pubis, abdominal strain, and athletic pubalgia. Magnetic resonance imaging (MRI) showed a small partial sports hernia with the shearing of the aponeurotic plate. The team physician recommended conservative management. The patient requested a consultation with a …
Divergent Sensory Transcriptomic Profiles In Positive And Negative Learning In Bicyclus Anynana Butterflies, Yi Ting Ter, Erica L. Westerman
Divergent Sensory Transcriptomic Profiles In Positive And Negative Learning In Bicyclus Anynana Butterflies, Yi Ting Ter, Erica L. Westerman
Biological Sciences Faculty Publications and Presentations
Mate preference learning, where individuals learn to prefer or avoid specific phenotypes during mate selection, is pervasive across animal taxa and influences reproductive isolation and trait evolution. Despite its significance, the genetic basis underlying the associated valence attribution (whether to prefer or avoid) remains largely unclear. Both in terms of what genes are associated with attributing valence, and whether valence attribution is associated with transcriptional changes in both sensory tissues and neural circuits in the brain, or is restricted to the brain. Here, we investigate the neurogenomic basis of positive and negative mate preference learning using Bicyclus anynana butterflies. We …