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Articles 5221 - 5250 of 20451

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Making A First Impression: Exploring What Instructors Do And Say On The First Day Of Introductory Stem Courses, A. Kelly Lane, Clara L. Meaders, J. Kenny Shuman, Mackenzie R. Stetzer, Erin L. Vinson, Brian A. Couch, Michelle K. Smith, Marilyne Stains Oct 2020

Making A First Impression: Exploring What Instructors Do And Say On The First Day Of Introductory Stem Courses, A. Kelly Lane, Clara L. Meaders, J. Kenny Shuman, Mackenzie R. Stetzer, Erin L. Vinson, Brian A. Couch, Michelle K. Smith, Marilyne Stains

School of Biological Sciences: Faculty Publications

Student impressions formed during the first day of class can impact course satisfaction and performance. Despite its potential importance, little is known about how instructors format the first day of class. Here, we report on observations of the first day of class in 23 introductory science, technology, engineering, and math (STEM) courses. We first described how introductory STEM instructors structure their class time by characterizing topics covered on the first day through inductive coding of class videos. We found that all instructors discussed policies and basic information. However, a cluster analysis revealed two groups of instructors who differed primarily in …

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Atlantic Salmon (Salmo Salar) Neurocranium, Connor Depriest, Nadia Abeido, David Kerstetter Oct 2020

Atlantic Salmon (Salmo Salar) Neurocranium, Connor Depriest, Nadia Abeido, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

9.0 cm in length. Neurocranium scan of an Atlantic Salmon (Salmo salar). Collected from Two Bills Seafood on 04/09/20 by Nadia Abeido and Connor Depriest.

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Comparable Human Reconstitution Following Cesium-137 Versus X-Ray Irradiation Preconditioning In Immunodeficient Nog Mice, Anna Halling Folkmar Andersen, Stine Sofie Frank Nielsen, Rikka Olesen, Jakob Le Fèvre Harslund, Ole S. Søgaard, Lars Østergaard, Paul Denton, Martin Tolstrup Oct 2020

Comparable Human Reconstitution Following Cesium-137 Versus X-Ray Irradiation Preconditioning In Immunodeficient Nog Mice, Anna Halling Folkmar Andersen, Stine Sofie Frank Nielsen, Rikka Olesen, Jakob Le Fèvre Harslund, Ole S. Søgaard, Lars Østergaard, Paul Denton, Martin Tolstrup

Biology Faculty Publications

Humanized mouse models are used extensively in research involving human pathogens and diseases. However, most of these models require preconditioning. Radio-active sources have been used routinely for this purpose but safety issues have motivated researchers to transition to chemical or X-ray based preconditioning. In this study, we directly compare 350 kV X-ray and Cs-137 low-dose precondition of NOG mice before human stem cell transplantation. Based on flow cytometry data, we found that engraftment of human cells into the mouse bone marrow was similar between radiation sources. Likewise, human engraftment in the peripheral blood was comparable between Cs-137 and three different …

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Hypogean Communities As Cybernetic Systems: Implications For The Evolution Of Cave Biotas, Aldemaro Romero Jr. Oct 2020

Hypogean Communities As Cybernetic Systems: Implications For The Evolution Of Cave Biotas, Aldemaro Romero Jr.

Publications and Research

Ramón Margalef proposed in 1968 that ecosystems could be better understood if they were viewed as cybernetic systems. I tested this hypothesis in the case of hypogean ecosystems using available pieces of evidence. I looked on how information on feedbacks, stability, succession, organization, diversity, and energy flows in the hypogean environment fit the cybernetics hypothesis. The results were that there are convincing arguments that the application of the concept of cybernetics in biospeleology can be beneficial to broadening our understanding of cave biota in terms of their structure. I also make the case that this approach can provide more clarity …

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Inheritability Of Ciprofloxacin-Induced Mitochondrial Mutations From Parental To Offspring Generation Using Quantitative Polymerase Chain Reaction, Rose Mccoy Oct 2020

Inheritability Of Ciprofloxacin-Induced Mitochondrial Mutations From Parental To Offspring Generation Using Quantitative Polymerase Chain Reaction, Rose Mccoy

Honors Program: Senior Projects (Public)

In all eukaryotes, mitochondria are known as the powerhouse of the cell (Siekevitz, 1957). In plants, however, their mitochondrial genome is especially strange. Plant mitochondrial genomes are extremely large and contain both linear and circular subgenomic DNA fragments. Plant mitochondrial genomes undergo a significant amount of mutations in the form of rearrangements. However, it is not known how often these rearrangements are inherited by the next generation. It is thought that plant cells that are still dividing have higher rates of DNA repair, such as double-strand break repair, to ensure the quality of that plant lineage. As follows, it is …

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Identification Of Planktothrix (Cyanobacteria) Blooms And Effects On The Aquatic Macroinvertebrate Community In The Non-Tidal Potomac River, Usa, Joshua Henesy, Jennifer L. Wolny, John E. Mullican, Detbra S. Rosales, Joseph S. Pitula, Joseph W. Love Oct 2020

Identification Of Planktothrix (Cyanobacteria) Blooms And Effects On The Aquatic Macroinvertebrate Community In The Non-Tidal Potomac River, Usa, Joshua Henesy, Jennifer L. Wolny, John E. Mullican, Detbra S. Rosales, Joseph S. Pitula, Joseph W. Love

Virginia Journal of Science

Using transverse cross-sectional transects, a survey of 31 km of the non-tidal Potomac River was conducted from White’s Ferry, Virginia to Brunswick, Maryland, USA, between June and September in 2013 through 2015 to assess a recurring benthic cyanobacteria bloom. Abundant benthic cyanobacteria blooms were detected during the 2014 and 2015 sampling seasons and the primary taxon was identified morphologically and molecularly as Planktothrix cf. isothrix. When present, P. cf. isothrix blooms were concentrated from river center to the Maryland shoreline. This pattern was correlated with significantly greater benthic chlorophyll-a and phycocyanin concentrations. In an apparent response to …

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Tadpole Of The Amazonia Frog Edalorhina Perezi (Anura: Leptodactylidae) With Description Of Oral Internal And Chondrocranial Morphology, Filipe A.C Do Nascimento, Rafael O. De Sá, Paulo C. De A. Garcia Oct 2020

Tadpole Of The Amazonia Frog Edalorhina Perezi (Anura: Leptodactylidae) With Description Of Oral Internal And Chondrocranial Morphology, Filipe A.C Do Nascimento, Rafael O. De Sá, Paulo C. De A. Garcia

Biology Faculty Publications

The genus Edalorhina consists of two species of small forest-floor frogs inhabiting the Amazon basin. The tadpole of Edalorhina perezi, the most widely distributed species, was previously described based on a single and early stage (Gosner 25) individual. Herein, we provide a description of the tadpole in Gosner stages 35–36 including internal morphology data (i.e., buccopharyngeal cavity and larval skeleton) based on samples from two populations from Ecuador. Edalorhina shares a generalized morphology with most members of its closely related taxa; however, it is distinguished from the other species by having an almost terminal oral disc. The presence of …

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Survivor Microbial Populations In Post-Chlorinated Wastewater Are Strongly Associated With Untreated Hospital Sewage And Include Ceftazidime And Meropenem Resistant Populations, Rachelle E. Beattie, Troy Skwor, Krassimira R. Hristova Oct 2020

Survivor Microbial Populations In Post-Chlorinated Wastewater Are Strongly Associated With Untreated Hospital Sewage And Include Ceftazidime And Meropenem Resistant Populations, Rachelle E. Beattie, Troy Skwor, Krassimira R. Hristova

Biological Sciences Faculty Research and Publications

Wastewater treatment plant (WWTP) effluent has been implicated in the spread of antibiotic resistant bacteria (ARB), including pathogens, as the WWTP environment contains multiple selective pressures that may increase mutation rates, pathogen survivability, and induce gene transfer between bacteria. In WWTPs receiving hospital sewage, this selective effect may be more pronounced due to increased concentrations of antibiotics, ARB, and clinical pathogens from hospital sewage. To determine the extent to which hospital sewage contributes to the microbial community of disinfected wastewater which is released into the environment, we used 16S rRNA sequencing of hospital sewage, WWTP influent, primary effluent, Post-Chlorinated Effluent, …

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Draft Genome Of Bugula Neritina, A Colonial Animal Packing Powerful Symbionts And Potential Medicines, Mikhail Rayko, Aleksey Komissarov, Jason C. Kwan, Grace Lim-Fong, Adelaide C. Rhodes, Sergey Kliver, Polina Kuchur, Stephen James O'Brien, Jose Lopez Oct 2020

Draft Genome Of Bugula Neritina, A Colonial Animal Packing Powerful Symbionts And Potential Medicines, Mikhail Rayko, Aleksey Komissarov, Jason C. Kwan, Grace Lim-Fong, Adelaide C. Rhodes, Sergey Kliver, Polina Kuchur, Stephen James O'Brien, Jose Lopez

Biology Faculty Articles

Many animal phyla have no representatives within the catalog of whole metazoan genome sequences. This dataset fills in one gap in the genome knowledge of animal phyla with a draft genome of Bugula neritina (phylum Bryozoa). Interest in this species spans ecology and biomedical sciences because B. neritina is the natural source of bioactive compounds called bryostatins. Here we present a draft assembly of the B. neritina genome obtained from PacBio and Illumina HiSeq data, as well as genes and proteins predicted de novo and verified using transcriptome data, along with the functional annotation. These sequences will permit a better …

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Novel Information About The Kinetic Effects Of Equine Shoe Modifications And Kinematic Effects Of Human Digital Devices For Improved Performance In Both Species, Pengju Wang Oct 2020

Novel Information About The Kinetic Effects Of Equine Shoe Modifications And Kinematic Effects Of Human Digital Devices For Improved Performance In Both Species, Pengju Wang

LSU Master's Theses

Equine shoes are frequently modified to enhance traction for horses that travel on paved surfaces for work, pleasure, or entertainment. Little is known about other common shoe modifications used to enhance traction like calks, tungsten carbide granules, or plastic composition. This information is vital to shoe design to protect the safety and welfare of all service, working, and leisure horses. The objective of the first part of this thesis was to quantify the effect of shoes with and without traction adaptions on kinetic measures in non-lame, light breed horses at a trot. Kinetic data was collected with a force platform …

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Identification And Characterization Of Novel Genes And Genetic Interactions That Influence Iba Metabolism, Vanessica Jawahir Oct 2020

Identification And Characterization Of Novel Genes And Genetic Interactions That Influence Iba Metabolism, Vanessica Jawahir

Dissertations

Indole-3-butyric acid (IBA) is an endogenous storage auxin important for maintaining appropriate indole-3-acetic acid (IAA) levels that influences primary root elongation and lateral root development. IBA is metabolized into free IAA in the peroxisome in a multistep process similar to fatty acid β-oxidation. Although many components specific to IBA metabolism and peroxisome function have been identified, our understanding is incomplete. I sought to identify novel components of IBA metabolism or peroxisome function by conducting a forward genetic screen for Arabidopsis thaliana plants with enhanced resistance to IBA. I identified Long chain acyl-CoA synthetase 4 (LACS4) as a novel gene functioning …

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Red Lionfish (Pterois Volitans) Neurocranium, Matthew B. Edwards, David W. Kerstetter Oct 2020

Red Lionfish (Pterois Volitans) Neurocranium, Matthew B. Edwards, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from a Lionfish (Pterois volitans) collected from whole foods supermarket on 11/9/2020

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Effect Of Three Classroom Research Experiences On Science Attitudes, Lauren K. Lucas, Frances K. Hunter, Zachariah Gompert Oct 2020

Effect Of Three Classroom Research Experiences On Science Attitudes, Lauren K. Lucas, Frances K. Hunter, Zachariah Gompert

Journal on Empowering Teaching Excellence

Here we evaluate undergraduate student attitudes about science after each of three authentic research experiences in a semester of an introductory biology laboratory course at Utah State University. The three course-based research experiences (CUREs) vary in length and student freedom, and they cover different areas of biology. Students responded to the science attitude items of the CURE Survey. When compared to national data, our students faired similarly, and all students struggled with certain epistemic assumptions about science knowledge. As also seen in the national database, change in science attitude was slight and nonlinear. Student self confidence in what a career …

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Artificial Nightlight Alters The Predator–Prey Dynamics Of An Apex Carnivore, Mark A. Ditmer, David C. Stoner, Clinton D. Francis, Jesse R. Barber, James D. Forster, David M. Choate, Kirsten E. Ironside, Kathleen M. Longshore, Kent R. Hersey, Randy T. Larsen, Brock R. Mcmillan, Daniel D. Olson, Alyson M. Andreasen, Jon P. Beckmann, P. Brandon Holton, Terry A. Messmer, Neil H. Carter Oct 2020

Artificial Nightlight Alters The Predator–Prey Dynamics Of An Apex Carnivore, Mark A. Ditmer, David C. Stoner, Clinton D. Francis, Jesse R. Barber, James D. Forster, David M. Choate, Kirsten E. Ironside, Kathleen M. Longshore, Kent R. Hersey, Randy T. Larsen, Brock R. Mcmillan, Daniel D. Olson, Alyson M. Andreasen, Jon P. Beckmann, P. Brandon Holton, Terry A. Messmer, Neil H. Carter

Life Sciences Faculty Research

Artificial nightlight is increasingly recognized as an important environmental disturbance that influences the habitats and fitness of numerous species. However, its effects on wide‐ranging vertebrates and their interactions remain unclear. Light pollution has the potential to amplify land‐use change, and as such, answering the question of how this sensory stimulant affects behavior and habitat use of species valued for their ecological roles and economic impacts is critical for conservation and land‐use planning. Here, we combined satellite‐derived estimates of light pollution, with GPS‐data from cougars Puma concolor (n = 56), mule deer Odocoileus hemionus (n = 263) and locations of cougar‐killed …

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Field Evaluation Of Recombinant Antigen Elisa In Detecting Zoonotic Schistosome Infection Among Water Buffaloes In Endemic Municipalities In The Philippines, Jose Ma. M. Angeles, Yasuyuki Goto, Masahi Kirinoki, Elena A. Villacorte, Kharleezelle J. Moendeg, Pilarita T. Rivera, Yuichi Chigusa, Shin-Ichiro Kawazu Oct 2020

Field Evaluation Of Recombinant Antigen Elisa In Detecting Zoonotic Schistosome Infection Among Water Buffaloes In Endemic Municipalities In The Philippines, Jose Ma. M. Angeles, Yasuyuki Goto, Masahi Kirinoki, Elena A. Villacorte, Kharleezelle J. Moendeg, Pilarita T. Rivera, Yuichi Chigusa, Shin-Ichiro Kawazu

Biology Faculty Publications

In this study, we investigated the use of recombinant antigens thioredoxin peroxidase-1 (rSjTPx-1) and tandem repeat rSj1TR in evaluating the antibody positivity rates of Schistosoma japonicum infection among water buffaloes from four endemic areas in the Philippines, two municipalities with high endemicity (Calatrava, Negros Occidental and Catarman, Northern Samar) and two municipalities nearing elimination with no cases of human schistosomiasis (Talibon and Trinidad, Bohol). These recombinant antigen ELISA assays were compared with other diagnostic tests including SEA-ELISA, FECT, and fecal-based PCR. Results showed that rSj1TR-ELISA has the highest agreement with PCR in all study areas. Furthermore, significant positivity rates among …

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Freshwater Sediment Microbial Communities Are Not Resilient To Disturbance From Agricultural Land Runoff, Rachelle E. Beattie, Aditya Bandla, Sanjay Swarup, Krassimira R. Hristova Oct 2020

Freshwater Sediment Microbial Communities Are Not Resilient To Disturbance From Agricultural Land Runoff, Rachelle E. Beattie, Aditya Bandla, Sanjay Swarup, Krassimira R. Hristova

Biological Sciences Faculty Research and Publications

Microorganisms are critically important for the function of surface water ecosystems but are frequently subjected to anthropogenic disturbances at either acute (pulse) or long-term (press) scales. Response and recovery of microbial community composition and function following pulse disturbance is well-studied in controlled, laboratory scale experiments but is less well-understood in natural environments undergoing continual press disturbance. The objectives of this study were to determine the drivers of sediment microbial compositional and functional changes in freshwaters receiving continual press disturbance from agricultural land runoff and to evaluate the ability of the native microbial community to resist disturbance related changes as a …

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Bioinformatic Analysis Of Venom Proteins From Dasymutilla Occidentalis, Eva Gunawan Oct 2020

Bioinformatic Analysis Of Venom Proteins From Dasymutilla Occidentalis, Eva Gunawan

Theses and Dissertations

Venom proteins have been found in a wide range of species in the animal kingdom. These venoms serve various functions such as defense against predators, hunting for food, and parasitism for reproduction. Because of their diverse functions, venom proteins are utilized in agrochemical treatments for protection from pests as well as treatments to control human diseases. Venoms, including those coming from a range of insect species, have been manipulated for these purposes, but many remain uncharacterized. Currently, one of the orders that venom-based research is focusing on are parasitoids from the order Hymenoptera. The purpose of some venom proteins in …

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Spatiotemporal Analysis Of Cochlear Nucleus Innervation By Spiral Ganglion Neurons That Serve Distinct Regions Of The Cochlea, Jennifer L. Scheffel, Samiha S. Mohammed, Chloe K. Borcean, Annie J. Parng, Hyun Ju Yoon, Darwin A. Gutierrez, Wei-Ming Yu Oct 2020

Spatiotemporal Analysis Of Cochlear Nucleus Innervation By Spiral Ganglion Neurons That Serve Distinct Regions Of The Cochlea, Jennifer L. Scheffel, Samiha S. Mohammed, Chloe K. Borcean, Annie J. Parng, Hyun Ju Yoon, Darwin A. Gutierrez, Wei-Ming Yu

Biology: Faculty Publications and Other Works

Cochlear neurons innervate the brainstem cochlear nucleus in a tonotopic fashion according to their sensitivity to different sound frequencies (known as the neuron’s characteristic frequency). It is unclear whether these neurons with distinct characteristic frequencies use different strategies to innervate the cochlear nucleus. Here, we use genetic approaches to differentially label spiral ganglion neurons (SGNs) and their auditory nerve fibers (ANFs) that relay different characteristic frequencies in mice. We found that SGN populations that supply distinct regions of the cochlea employ different cellular strategies to target and innervate neurons in the cochlear nucleus during tonotopic map formation. ANFs that will …

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Effects Of Low-Level Artificial Light At Night On Kentucky Bluegrass And Introduced Herbivore, Morgan Crump, Cassandra Brown, Robert J. Griffin-Nolan, Lisa Angeloni, Nathan P. Lemoine, Brett Seymoure Oct 2020

Effects Of Low-Level Artificial Light At Night On Kentucky Bluegrass And Introduced Herbivore, Morgan Crump, Cassandra Brown, Robert J. Griffin-Nolan, Lisa Angeloni, Nathan P. Lemoine, Brett Seymoure

Biological Sciences Faculty Research and Publications

Increasing evidence suggests that artificial light at night (ALAN) can negatively impact organisms. However, most studies examine the impacts of ALAN on a single species or under high levels of artificial light that are infrequent or unrealistic in urban environments. We currently have little information on how low levels of artificial light emanating from urban skyglow affect plants and their interactions with herbivores. We examined how low levels of ALAN affect grass and insects, including growth rate, photosynthesis, and stomatal conductance in grass, and foraging behavior and survival in crickets. We compared growth and leaf-level gas exchange of Kentucky Bluegrass …

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The Best Predictions In Experimental Biology Are Critical And Persuasive, Douglas S. Fudge, Andy J. Turko Oct 2020

The Best Predictions In Experimental Biology Are Critical And Persuasive, Douglas S. Fudge, Andy J. Turko

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

A powerful way to evaluate scientific explanations (hypotheses) is to test the predictions that they make. In this way, predictions serve as an important bridge between abstract hypotheses and concrete experiments. Experimental biologists, however, generally receive little guidance on how to generate quality predictions. Here, we identify two important components of good predictions – criticality and persuasiveness – which relate to the ability of a prediction (and the experiment it implies) to disprove a hypothesis or to convince a skeptic that the hypothesis has merit. Using a detailed example, we demonstrate how striving for predictions that are both critical and …

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Escolar (Lepidocybium Flavobrunneum) Neurocranium, Meredith M. Pratt, Katerina D. Sawickij, David W. Kerstetter Oct 2020

Escolar (Lepidocybium Flavobrunneum) Neurocranium, Meredith M. Pratt, Katerina D. Sawickij, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium prep of escolar Lepidocybium flavobrunneum obtained from longlining vessel.

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Influence Of Characteristics Of Marine Macroalgae On Feeding Preferences Of The Milkfish (Chanos Chanos) In Peninsular Malaysia, Lim Wai Yin Oct 2020

Influence Of Characteristics Of Marine Macroalgae On Feeding Preferences Of The Milkfish (Chanos Chanos) In Peninsular Malaysia, Lim Wai Yin

Student Works (2020-2029)

Herbivores can alter several ecological mechanisms including interactions between native and non-native autotrophs that may determine invasion success of the non-native autotrophs. This study looked into the autotroph-herbivore interactions in coastal marine ecosystems of Peninsular Malaysia, mainly to determine if autotroph nutritional components and geographical differences significantly influence herbivore feeding behaviours. The relative consumption rate (RCR) of milkfish (Chanos chanos Forsskål), a generalist herbivore obtained from the Straits of Malacca was documented through feeding trials using 12 macroalgal species collected from different coastal areas of the Straits of Malacca, the Straits of Johor, and the South China Sea. The herbivore …

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A Systematic Mapping Study On The Risk Factors Leading To Type Ii Diabetes Mellitus, Karar N. J Musafer, Fahrul Zaman Huyop, Mufeed J Ewadh, Eko Supriyanto, Mohammad Rava Oct 2020

A Systematic Mapping Study On The Risk Factors Leading To Type Ii Diabetes Mellitus, Karar N. J Musafer, Fahrul Zaman Huyop, Mufeed J Ewadh, Eko Supriyanto, Mohammad Rava

Karbala International Journal of Modern Science

Diabetes is one of the most common diseases that has had devastating effects on the general population. It is also among the most popular research trends in modern medicine. Thus, due to the complexity and desirability of this particular affliction, there is a lot of demand towards understanding this disease better, so that it can pave the way towards better solutions in combating diabetes. The aim of this review is to provide a categorization of the risk factors leading to Type II Diabetes. In order to provide a justification for the type of diabetes, an explanation is provided which covers …

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Generation Of Fluorescent Esophageal Adenocarcinoma Cells For Lineage Tracing Within Composite 3d Culture Models, Madeline G. Linker Oct 2020

Generation Of Fluorescent Esophageal Adenocarcinoma Cells For Lineage Tracing Within Composite 3d Culture Models, Madeline G. Linker

S.U.R.E Posters

While relatively rare, the aggressive nature and poor prognosis associated with esophageal carcinoma make it a particularly dangerous form of cancer. One approach to discovering esophageal cancer treatment options includes the development of composite 3D culture models. This method of research allows cellular interactions and responses toward interventions to be evaluated within a more complex system than 2D cultures. Additionally, a composite 3D model provides a higher throughput and is more cost-effective than in vivo animal studies. To analyze the interactions between the model’s cell types, fluorescent labeling allows each cell type to be distinguished from the others, facilitating independent …

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Diet Analysis Of Gastrotricha, Mikhail Anfinson Oct 2020

Diet Analysis Of Gastrotricha, Mikhail Anfinson

S.U.R.E Posters

The phylum Gastrotricha is comprised of small aquatic organisms that live in between sand grains. It has been shown that meiofauna communities can play valuable roles in ecosystems and serve as a food source for animals higher up the trophic levels. However, little is known about their own feeding behavior which this study is concerned about. Over the summer developments were made in the methodical sections for diet diagnostic PCR for marine bacterial strains, unicellular marine eukaryotes, and investigating different types of immunofluorescence for marine bacteria. We also plan at looking at the number of sarcomeres within the pharynx of …

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Character Displacement In The Midst Of Substantial Background Evolution In Anolis Lizard Island Populations, Ambika Kamath, Nicholas C. Herrmann, Kiyoko M. Gotanda, Kum C. Shim, Jacob Lafond, Gannon Cottone, Heather Falkner, Todd S. Campbell, Yoel E. Stuart Oct 2020

Character Displacement In The Midst Of Substantial Background Evolution In Anolis Lizard Island Populations, Ambika Kamath, Nicholas C. Herrmann, Kiyoko M. Gotanda, Kum C. Shim, Jacob Lafond, Gannon Cottone, Heather Falkner, Todd S. Campbell, Yoel E. Stuart

Biology: Faculty Publications and Other Works

Negative interactions between species can generate divergent selection that causes character displacement. However, other processes cause similar divergence. We use spatial and temporal replication across island populations of Anolis lizards to assess the importance of negative interactions in driving trait shifts. Previous work showed that the establishment of Anolis sagrei on islands drove resident Anolis carolinensis to perch higher and evolve larger toepads. To further test the interaction's causality and predictability, we resurveyed a subset of islands nine years later. Anolis sagrei had established on one island between surveys. We found that A. carolinensis on this island now perch higher …

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All-Atomic Molecular Dynamic Studies Of Human And Drosophila Cdk8: Insights Into Their Kinase Domains, The Lxxll Motifs, And Drug Binding Site, Wu Xu, Xiao-Jun Xie, Ali K. Faust, Mengmeng Liu, Xiao Li, Feng Chen, Ashlin A. Naquin, Avery C. Walton, Peter W. Kishbaugh, Jun-Yuan Ji Oct 2020

All-Atomic Molecular Dynamic Studies Of Human And Drosophila Cdk8: Insights Into Their Kinase Domains, The Lxxll Motifs, And Drug Binding Site, Wu Xu, Xiao-Jun Xie, Ali K. Faust, Mengmeng Liu, Xiao Li, Feng Chen, Ashlin A. Naquin, Avery C. Walton, Peter W. Kishbaugh, Jun-Yuan Ji

Faculty Publications

Cyclin-dependent kinase 8 (CDK8) and its regulatory partner Cyclin C (CycC) play conserved roles in modulating RNA polymerase II (Pol II)-dependent gene expression. To understand the structure and function relations of CDK8, we analyzed the structures of human and Drosophila CDK8 proteins using molecular dynamics simulations, combined with functional analyses in Drosophila. Specifically, we evaluated the structural differences between hCDK8 and dCDK8 to predict the effects of the LXXLL motif mutation (AQKAA), the P154L mutations, and drug binding on local structures of the CDK8 proteins. First, we have observed that both the LXXLL motif and the kinase activity of CDK8 …

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Cardiac Neuroanatomy And Chronotropic Modulation Of The Adult Giant Danio Heart, Alyssa Koch, Emma Nelson, Pascal Lafontant Oct 2020

Cardiac Neuroanatomy And Chronotropic Modulation Of The Adult Giant Danio Heart, Alyssa Koch, Emma Nelson, Pascal Lafontant

Annual Student Research Poster Session

Studies in non-mammalian models species have contributed significantly to our understanding of the biology and the nature of innervation in the heart. The giant danio (D. malabaricus) is a teleost fish species closely related to zebrafish, that is also capable of heart regeneration. We previously described the development and maturation of the giant danio (GD) heart. However, little is known about its innervation. We hypothesized that the pattern of innervation in the GD heart is anatomically and physiologically complex, and that the heart is responsive to physiological modulation similar to that seen in cyprinid fish and mammals. Using various neuronal …

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Alternative Treatments To Koalas With Chlamydia, Kelsey Thornton Oct 2020

Alternative Treatments To Koalas With Chlamydia, Kelsey Thornton

Fall Showcase for Research and Creative Inquiry

Koala populations have declined rapidly in the past 2 decades due to many reasons such as disease, vehicle collisions, dog attacks, urbanization and deforestation, and climate-related issues. Chlamydia is one of the leading causes for population declines in koalas. Koalas are difficult to treat for chlamydia because antibiotic treatment kills the specialized gut bacteria they have and need for degrading toxic compounds within eucalyptus leaves, their only source of food. I propose that doxycycline, a drug with a 97% cure rate and reduced dysbiosis, to be administered at higher concentrations less frequently. Additionally, I propose that koalas treated with antibiotics …

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The Secrets Of Sobek – A Crocodile Mummy Mitogenome From Ancient Egypt, Evon R. Hekkala, Matthew L. Aardema, Apurva Narechania, George Amato, Salima Ikram, Matthew H. Shirley, Kent A. Vliet, Seth W. Cunningham, M. Thomas P. Gilbert, Oliver Smith Oct 2020

The Secrets Of Sobek – A Crocodile Mummy Mitogenome From Ancient Egypt, Evon R. Hekkala, Matthew L. Aardema, Apurva Narechania, George Amato, Salima Ikram, Matthew H. Shirley, Kent A. Vliet, Seth W. Cunningham, M. Thomas P. Gilbert, Oliver Smith

Department of Biology Faculty Scholarship and Creative Works

Previous investigations of genetic diversity across the distribution of the Nile crocodile (Crocodylus niloticus) confirmed the existence of two genetically distinct species of true crocodile (genus Crocodylus) in Africa. These taxa correspond roughly to an eastern/southern African species (Crocodylus niloticus) and a central/western African species (Crocodylus suchus). Analysis of historical museum specimens demonstrated that both species existed concurrently in the Sudanese Nile until the early 20th century and genetic analyses of historical museum specimens of mummified crocodile hatchlings from Egyptian tombs located along Egyptian Nile were found to be C. suchus. Here we present the first assessment of mitogenomic data …

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