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Monitoring Racoon Rabies In Alabama: The Potential Effects Of Habitat And Demographics, Wendy M. Arjo, Christine E. Fisher, James Armstrong, Dana Johnson, Frank Boyd May 2005

Monitoring Racoon Rabies In Alabama: The Potential Effects Of Habitat And Demographics, Wendy M. Arjo, Christine E. Fisher, James Armstrong, Dana Johnson, Frank Boyd

Wildlife Damage Management Conference

Density, morphometrics, and disease prevalence of raccoon populations were determined in 4 habitats (agriculture, riverine, managed, and forested) in central Alabama. In addition we monitored 71 collared raccoons to determine survival. Density estimates were similar in the agriculture (ag) and riverine habitats in central Alabama with 8 raccoons/km2, and lower in the forested habitat at 5 raccoons/ km2. Retention of juveniles did not appear to contribute to observed higher populations in the riverine and ag habitat. Although the riverine and ag, possibly due to supplemental resources, likely provide better habitat for raccoons, we found only body …

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Black-Tailed Prairie Dog Colony Dynamics In South Dakota Over A 10-Year Period, Kathleen A. Fagerstone, Howard P. Tietjen, James F. Glahn, Greg L. Schenbeck, Jean Bourassa May 2005

Black-Tailed Prairie Dog Colony Dynamics In South Dakota Over A 10-Year Period, Kathleen A. Fagerstone, Howard P. Tietjen, James F. Glahn, Greg L. Schenbeck, Jean Bourassa

Wildlife Damage Management Conference

Between 1968 and 1978, aerial photography was used to monitor distribution of black-tailed prairie dog (Cynomys ludovicianus) colonies on a 400-square mile area in South Dakota, including parts of Buffalo Gap National Grassland, Pine Ridge Indian Reservation, and Badlands National Monument (now Badlands National Park). Aerial photographs were taken of the study area in 1968 and annually from 1974 through 1978 at a scale of 1:20,000 (1968) and 1:15,840 (1974-1978). Prairie dog colonies were identified on the photographs, outlined, and the outline transferred to USGS topographic maps for colony size measurements. This technique reliably detected changes in prairie …

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The Role Of Raccoons In The Ecology Of Bovine Tuberculosis, Kurt C. Vercauteren, Holy J. Smith, Justin S. Stevenson May 2005

The Role Of Raccoons In The Ecology Of Bovine Tuberculosis, Kurt C. Vercauteren, Holy J. Smith, Justin S. Stevenson

Wildlife Damage Management Conference

Bovine tuberculosis is a contagious bacterial disease that has had significant socioeconomic impacts on the region of northern lower Michigan. The role raccoons may play in the ecology and maintenance of the disease on farms in the core disease is unknown. Preliminary results of 61 radio collared raccoons have yielded a better understanding of raccoon movement and habitat use within an agricultural complex. Preliminary analysis of raccoons suggests annual home range sizes of .824km2 and .608km2 for males and females, respectively. Additionally raccoons and cattle have been documented at resource interfaces, further illustrating the potential for indirect disease …

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Evaluation Of A New Strategy For Control Of Bovine Tuberculosis In Michigan White-Tailed Deer: Year 1 Progress Report, Stephen Schmitt, Daniel O'Brien, Elaine Carlson, David Smith, Zachary Cooley, Brent Rudolph, Graham Hickling, Graham Nugent, Peter Butchko May 2005

Evaluation Of A New Strategy For Control Of Bovine Tuberculosis In Michigan White-Tailed Deer: Year 1 Progress Report, Stephen Schmitt, Daniel O'Brien, Elaine Carlson, David Smith, Zachary Cooley, Brent Rudolph, Graham Hickling, Graham Nugent, Peter Butchko

Wildlife Damage Management Conference

The State of Michigan is striving to eliminate bovine tuberculosis (Tb) infection among free-ranging white-tailed deer in the northeastern Lower Peninsula of the state. Aggressive reduction in the overall deer population abundance may help to further reduce TB prevalence, but this course of action is unacceptable to many hunters and landowners. Targeted culling of sick deer would likely be far more acceptable to these stakeholders, so in the winter of 2003 the Michigan Department of Natural Resources pilot-trialed a new strategy based on live-trapping and Tb-testing of wild deer. The field study was conducted in a township with relatively high …

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Conditioning Beaver To Avoid Desirable Plants, Julie L. Harper, Dale L. Nolte, Thomas J. Deliberto, David L. Bergman May 2005

Conditioning Beaver To Avoid Desirable Plants, Julie L. Harper, Dale L. Nolte, Thomas J. Deliberto, David L. Bergman

Wildlife Damage Management Conference

Conditioned food aversion can be used to train animals to avoid select foods. Generally, aversive conditioning is best applied when animals first encounter a food item. However, almost by definition damage is inflicted to desirable plants very familiar to the culprit. We assessed the potential for training beaver to avoid a known preferred food. During a 5 day day treatment period beavers were offered only corn at 1600 hours. Six hours later, animals that had ingested corn were injected with 150 mg/kg lithium chloride (LiCl), with a control group receiving sodium chloride (NaCl). Alternate foods were then offered with corn …

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The Eradication Of Bovine Tuberculosis From Infected Wildlife Populations: A New Zealand Scenario, Garry J.E. Knowles, Mark Hunter, Amy Rush May 2005

The Eradication Of Bovine Tuberculosis From Infected Wildlife Populations: A New Zealand Scenario, Garry J.E. Knowles, Mark Hunter, Amy Rush

Wildlife Damage Management Conference

The Animal Health Board (AHB) is the agency responsible for controlling bovine tuberculosis (Tb) in New Zealand. In 2000, the AHB embarked on a strategy designed to reduce the annual period prevalence of Tb infected cattle and farmed deer herds from 1.67% to 0.2% by 2012/13. Under current rules of the Office International des Epizooties (OIE) this would allow New Zealand to claim freedom from Tb. The epidemiology of Tb in New Zealand is largely influenced by wildlife reservoirs of infection and control of Tb vector populations is central to the elimination of Tb from New Zealand's cattle and deer …

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Preliminary Serologic Survey Of Selected Diseases And Movements Of Feral Swine In Texas, A. Christy Wyckoff, Scott E. Henke, Tyler Campbell, David G. Hewitt, Kurt Vercauteren May 2005

Preliminary Serologic Survey Of Selected Diseases And Movements Of Feral Swine In Texas, A. Christy Wyckoff, Scott E. Henke, Tyler Campbell, David G. Hewitt, Kurt Vercauteren

Wildlife Damage Management Conference

Feral swine (Sus scrofa) populations occur throughout eastern, central, and southern Texas, and their populations appear to be increasing. Despite their abundance and wide distribution, little is known about their range and interaction with domestic animals. In the last decade the national pork production industry has enforced an eradication program for economically detrimental swine diseases such as pseudorabies and brucellosis. It is hypothesized that feral hogs can be reservoirs that could reintroduce diseases to disease-free domestic swine herds. The objectives of this on-going project are to determine the prevalence of selected swine diseases that exist within feral hog …

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Use Of Deer Repellents To Preserve Wildlife Food Plots For Game Birds, Wendy M. Arjo, Kimberly K. Wagner, Chad D. Richardson, Dale L. Nolte May 2005

Use Of Deer Repellents To Preserve Wildlife Food Plots For Game Birds, Wendy M. Arjo, Kimberly K. Wagner, Chad D. Richardson, Dale L. Nolte

Wildlife Damage Management Conference

Food plots are a vital element for the survival of game bird species such as bobwhite quail (Colinus virginianus) on Fort Riley Military Installation in Kansas. However, white-tailed deer (Odocoileus virginianus) tend to eat the sorghum when it starts to ripen in September and continue feeding on it through November and December, often leaving no food for the quail during the winter. We conducted pen and field trails to determine if repellents were an effective and feasible method to protect grain sorghum food plots from deer damage. Two-choice pen trials with both deer and game bird …

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Badger Movement Ecology In Colorado Agricultural Areas After A Fire, Craig A. Ramey, Jean B. Bourassa May 2005

Badger Movement Ecology In Colorado Agricultural Areas After A Fire, Craig A. Ramey, Jean B. Bourassa

Wildlife Damage Management Conference

While investigating the American badger (Taxidea taxus) in eastern Colorado' s wheatlands, we studied 3 badgers which were affected by a 2.1 km2 man-made fire and compared them to 2 adjacent badgers unaffected by the fire. All badgers were equipped with radio-telemetry collars and generally located day and night for approximately 1 month pre-fire and 3 weeks post-fire. Three point triangulation locations were converted into a global information system database. Adaptive kernel analyses compared pre- and post-fire horizontal: home ranges (i.e. 95% utilization areas, UAs), core activity areas (50% UAs), movements, den and habitat use patterns. Mean …

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Development Of Diazacon™ As An Avian Contraceptive, Christi A. Yoder, Kimberly S. Bynum, Lowell A. Miller May 2005

Development Of Diazacon™ As An Avian Contraceptive, Christi A. Yoder, Kimberly S. Bynum, Lowell A. Miller

Wildlife Damage Management Conference

Due to increasing human-wildlife conflicts with birds and growing opposition to lethal techniques, nonlethal methods need to be developed to help manage bird populations. DiazaCon™ is a promising oral contraceptive that acts by directly inhibiting the conversion of desmosterol to cholesterol. Because cholesterol is essential for the production of the steroid reproductive hormones testosterone, progesterone, and estradiol, DiazaCon™ also indirectly inhibits the formation of these hormones. These hormones are essential for sperm and egg production, and the production of egg yolk precursors in the liver. Because DiazaCon™ is cleared slowly from the liver, its contraceptive effects are long-lasting. Initial research …

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The Role Of Puf3 Protein Interactions In The Regulation Of Mrna Decay In Yeast Saccharomyces Cerevisiae, Shervin Sean Houshmandi May 2005

The Role Of Puf3 Protein Interactions In The Regulation Of Mrna Decay In Yeast Saccharomyces Cerevisiae, Shervin Sean Houshmandi

Dissertations

The regulation of messenger RNA (mRNA) metabolism is an important step in proper gene expression. In many eukaryotic organisms this regulation can be mediated by a group of highly conserved RNA-binding proteins known as the Puf family of proteins. The yeast Saccharomyces cerevisiae has several proteins that belong to this family. One of the yeast Puf proteins, Puf3p, binds and regulates the COX17 mRNA, which codes for a protein involved in mitochondrial copper transport. Specifically, Puf3p stimulates the decay of COX17 mRNA. However, the precise mechanism of Puf3p binding and decay regulation is yet unknown. The goal of this research …

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Relative Influence Of Landscape Indicators On Macroinvertebrate Communities In A Predominately Forested Watershed: Effects Of Spacial Scale, Robert Johnson May 2005

Relative Influence Of Landscape Indicators On Macroinvertebrate Communities In A Predominately Forested Watershed: Effects Of Spacial Scale, Robert Johnson

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Robert Johnson on May 9, 2005.

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The Effect Of Wildfire On Populations Of The Jemez Mountains Salamander (Plethodon Neomexicanus) With Consideration To Arthropod Prey Availability Following The Cerro Grande Fire Of Northern New Mexico, Michelle R. Cummer May 2005

The Effect Of Wildfire On Populations Of The Jemez Mountains Salamander (Plethodon Neomexicanus) With Consideration To Arthropod Prey Availability Following The Cerro Grande Fire Of Northern New Mexico, Michelle R. Cummer

Biology

Fire regimes in North America, including the American Southwest, have undergone relatively dramatic shifts in the last century, resulting in novel stand-replacing fires that are changing landscapes in unprecedented ways. Some possible effects of these novel landscape changes on a terrestrial plethodontid salamander (Plethodon neomexicanus) were investigated. Microhabitat temperatures in four burn-severity types following recent fires were measured. Temperatures were significantly greater in high-severity and moderate-severity burn areas than in low-severity and unburned areas. Salamander presence/absence data from four burn-severity types that were documented as having salamanders prior to wildfire are considered. The proportions of presence and absence …

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Physiological And Molecular Genetic Mechanisms Of Tetrodotoxin Resistance In The Garter Snake, Thamnophis Sirtalis, Shana L. Geffeney May 2005

Physiological And Molecular Genetic Mechanisms Of Tetrodotoxin Resistance In The Garter Snake, Thamnophis Sirtalis, Shana L. Geffeney

Biology

The focus of this project was the identification of physiological and molecular genetic mechanisms of tetrodotoxin resistance in the common garter snake, Thamnophis sirtalis. Tetrodotoxin, a neurotoxin, specifically blocks the activity of voltage-gated sodium channels. Some populations of garter snake have evolved geographically variable resistance to tetrodotoxin in a coevolutionary arms race with their tetrodotoxic prey, newts of the genus Taricha. Variation in tetrodotoxin resistance among snake populations is extreme and spans three orders of magnitude. Here I describe a physiological mechanism of whole-animal tetrodotoxin resistance in four populations of snake that represent two independent evolutionary origins of …

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Ecology And Physiology Of Tetrodotoxin Toxicity In The Newt Genus Taricha: Ramifications For A Coevolutionary Predator-Prey Interaction, Charles T. Hanifin May 2005

Ecology And Physiology Of Tetrodotoxin Toxicity In The Newt Genus Taricha: Ramifications For A Coevolutionary Predator-Prey Interaction, Charles T. Hanifin

Biology

I examined the ecology and physiology of tetrodotoxin (TTX) toxicity in the newt genus Taricha (family Salamandridae) to understand the forces that have shaped the adaptive evolution of TTX toxicity in this group. In particular, this work sought to explore how coevolution with a TTX-resistant predator (the garter snake, Thamnophis sirtalis) has shaped patterns of phenotypic diversity in TTX toxicity among populations of Taricha. I developed a set of techniques to directly measure levels of TTX in the skin of newts, and used those measurements to estimate the amount of TTX a snake predator would be exposed to …

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A Qualitative And Quantitative Characterization Of Emergent, Distributed Computation As A Possible Mechanism For Biological Information Processing In Stomatal Networks, Susanna M. Messinger May 2005

A Qualitative And Quantitative Characterization Of Emergent, Distributed Computation As A Possible Mechanism For Biological Information Processing In Stomatal Networks, Susanna M. Messinger

Biology

This research presents an exploration of the qualitative and quantitative properties of emergent, distributed computation in artificial cellular networks with the goal of better understanding the same computational mechanism as it might occur in biological systems, particularly plants. Stomata are tiny pores on the surface of a plant. As the sole pathway for the exchange of gasses between a plant and the atmosphere, stomata are responsible for both CO2 assimilation and water loss. By adjusting their pore size in response to environmental conditions, stomata appear to maximize carbon assimilation while minimizing water loss—a constrained optimization problem. Stomata interact with …

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Functional Diversity In Autotrophic Ammonia-Oxidizing Bacteria From Agricultural Soils, Teresa E. Koper May 2005

Functional Diversity In Autotrophic Ammonia-Oxidizing Bacteria From Agricultural Soils, Teresa E. Koper

Biology

Ammonia-oxidizing bacteria carry out the first step of nitrification, producing nitrite that is subsequently converted to nitrate, which may contribute to environmental pollution. The objective of this study was to gain insight into the functional diversity of ammonia-oxidizing bacteria in agricultural soils. We investigated the urease encoding gene sequences of several nitrifying bacteria and the kinetics of nitrification of soils treated with different nitrogen sources. Many, but not all, ammonia-oxidizing bacteria produce urease and are capable of hydrolyzing urea for their source of ammonium. The urease operons were sequenced from the betaproteobacterial Nitrosospira sp. NpAV and the gammaproteobacterial Nitrosococcus oceani. …

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Biotic And Abiotic Determinants Of Species Distribution: Desert Horned Lizards (Phrynosoma Platyrhinos) And Ants In A Shrub-Steppe Ecosystem, T. A. Scott Newbold May 2005

Biotic And Abiotic Determinants Of Species Distribution: Desert Horned Lizards (Phrynosoma Platyrhinos) And Ants In A Shrub-Steppe Ecosystem, T. A. Scott Newbold

Biology

The primary objective of this study was to attempt to disentangle the relative importance of biotic vs. abiotic factors on the distribution and abundance of desert horned lizards (Phrynosoma platyrhinos). Research was conducted along a Great Basin shrub-steppe bajada that examined interactions among P. platyrhinos, ants, plants, and soil characteristics. Studies focused on: (1) pattern description and habitat associations of P. platyrhinos, and (2) evaluating specific biotic and abiotic pathways underlying observed patterns of lizard abundance and distribution. Examination of lizard habitat associations along the elevational gradient revealed that unvegetated spaces and cryptobiotic crust cover were …

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Evolutionary History Of The Clitellariinae And Stratiomyidae (Insecta: Diptera) Using Molecular, Morphological, And Total Evidence Approaches, Colin A. Brammer May 2005

Evolutionary History Of The Clitellariinae And Stratiomyidae (Insecta: Diptera) Using Molecular, Morphological, And Total Evidence Approaches, Colin A. Brammer

Biology

Stratiomyidae is a diverse, cosmopolitan family of Diptera (true flies). One of its twelve subfamilies, Clitellariinae, is distributed in all major biogeographic regions except Antarctica. Understanding the evolutionary history of Clitellariinae is key to reconstructing the phylogeny of Stratiomyidae as a whole because Clitellariinae is united only by shared ancestral characters, and, thus, may not be a natural group. This research investigates the relationships between the genera currently placed within Clitellariinae and the subfamilial relationships of Stratiomyidae using morphology, molecules, and combined data. Morphology was analyzed with the method of parsimony using 97 adult characters. Molecular analyses were performed with …

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Yellow Starthistle In Utah: An Investigation Of Centaurea Solstitialis Invasion Patterns, Processes, And Population Dynamics, Julie Patrice Rieder May 2005

Yellow Starthistle In Utah: An Investigation Of Centaurea Solstitialis Invasion Patterns, Processes, And Population Dynamics, Julie Patrice Rieder

Biology

In a series of observational studies and experiments in the field, I investigated the general biology of yellow starthistle (Centaurea solstitialis) within a landscape in Utah in light of three main phases of invasion: arrival and establishment, spread, and equilibrium. During the establishment phase, the effect of disturbance on yellow starthistle establishment and performance was context dependent; disturbance positively influenced establishment and fecundity on relatively large disturbed plots that were artificially seeded, but had no significant effect on YST performance on small disturbed plots receiving ambient seed rain. Importantly, disturbance was not essential for establishment of yellow starthistle. …

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A Kinetic Analysis Of Bluetongue Virus Messenger Rna And Protein, Margaret K. Buccambuso May 2005

A Kinetic Analysis Of Bluetongue Virus Messenger Rna And Protein, Margaret K. Buccambuso

Biology

Bluetongue virus (BTV) of the family Reoviridae has a segmented double-stranded RNA (dsRNA) genome with ten dsRNA segments which encode seven structural proteins and four nonstructural proteins. Previous studies have revealed that newly synthesized RNA transcripts during viral replication were found in equimolar ratios within BTV virions. However, synthesized mRNA transcripts intended for translation into viral proteins are not equimolar. The levels of expression of these BTV mRNAs are still unknown although the number of viral proteins present in each BTV virion had been defined. The purpose of this research was to establish a kinetic analysis of the ten BTV …

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Testing Species Disputes And Population Genetics In The Genus Phragmatopoma Using Molecular Characters, Carrie A. Drake May 2005

Testing Species Disputes And Population Genetics In The Genus Phragmatopoma Using Molecular Characters, Carrie A. Drake

Biology

Phragmatopoma californica (found in the Pacific Ocean) and P. caudata (found in the Atlantic Ocean) are intertidal, marine reef-building polychaete worms that have been found to produce viable larvae in a laboratory setting, but are otherwise geographically isolated. The first study was aimed at determining their specific status by analyzing the DNA sequences of cytochrome c oxidase subunit I (COI) and the first internal transcribed spacer region (ITS-1). Phylogenetic analyses revealed that P. californica individuals shared no COI haplotypes or ITS-1 sequences with P. caudata individuals and formed well supported separate clades. The molecular data therefore supports the status of …

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Characterization Of Monoclonal Antibodies That Recognize Myxobolus Cerebralis, The Causative Agent Of Whirling Disease, Carey A. Wicks May 2005

Characterization Of Monoclonal Antibodies That Recognize Myxobolus Cerebralis, The Causative Agent Of Whirling Disease, Carey A. Wicks

Biology

Twenty-five monoclonal antibodies produced against myxospores and triactinomyxon spores of M. cerebralis, the causative agent of whirling disease of salmonids, were selected in the initial screening for their reactivity to myxospores. Twelve were found to be effective and accordingly they were characterized fully for their potential as diagnostic reagents for isolated myxospores, pre-spore stages, and spores in frozen sections. Comparative detection assays using enzyme linked immunosorbent assay (ELISA), immunofluorescent assay (IFA), and immuno dot-blot were conducted. Six antibodies bound to developing stages and mature spores of the parasite. Localization of antibody binding in IFA was affirmed by electron microscopy. …

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Hypoxia Signaling In Arabidopsis Thaliana, Julie C. Johnson May 2005

Hypoxia Signaling In Arabidopsis Thaliana, Julie C. Johnson

Biology

The oxygen level at or below which respiration is limited is termed hypoxia. Hypoxia can be induced by several different environmental factors, including flooding and microgravity. Plants have developed mechanisms to survive and acclimate to these conditions through changes in morphology, metabolic pathways, and protein synthesis. One mechanism used by plants to signal stress environments is a signal transduction pathway involving membrane phospholipids that can induce calcium mobilization, or the movement of calcium into the cytosol from extracellular or in-tracellular stores. However, the data from this study indicates that hypoxic stress did not result in phosphoinositide accumulation or calcium mobilization …

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Characterization Of Microbial Communities In Karstic Sediments : A Study Of Cave Bacteria In Central Kentucky., Justine Kay Roback 1964- May 2005

Characterization Of Microbial Communities In Karstic Sediments : A Study Of Cave Bacteria In Central Kentucky., Justine Kay Roback 1964-

Electronic Theses and Dissertations

Few previous studies have compared microbial communities in subterranean and surface environments. Chemical analyses used to characterize the surface and cave microbial environments indicated limited exchange between surface and subsurface waters. Here, bacterial communities from four distinct cave sediments collected in central Kentucky and adjacent surface streams were compared using a combination of culture and molecular methods. Predictions were that: 1) Cave communities will have unique community structures when compared to those of nearby surface sediments, and 2) Genetic diversity of bacterial communities in cave sediments will be higher than those in nearby surface sediments. Since diversity and community structure …

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The Mayfly Newsletter, Peter M. Grant May 2005

The Mayfly Newsletter, Peter M. Grant

The Mayfly Newsletter

The Mayfly Newsletter is the official newsletter of the Permanent Committee of the International Conferences on Ephemeroptera.

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The Effects Of Heavy Metals On The Cyanobacterium, Anacystis Nidulans, Suzen Sameer Awad May 2005

The Effects Of Heavy Metals On The Cyanobacterium, Anacystis Nidulans, Suzen Sameer Awad

Theses, Dissertations and Culminating Projects

Anacystis nidulans is a rod-shaped, freshwater cyanobacterium. Like other cyanobacteria, it is an obligate photoautotroph that is similar to gram-negative bacteria in cell wall structure, replication and ability to harbor plasmids. Anacystis nidulans is often used as an indicator of the presence and level of pollutants in the environment. Mercury, iron, cadmium, and zinc are among the heavy metal contaminants found in the environment and in bodies of freshwater through industrial discharges, agricultural runoff and sewage treatments. In very low concentrations, they do not pose any threat to the environment, but high concentrations can be lethal. Different microorganisms vary in …

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The Role Of Dosage Sensitive Sex Reversal Adrenal Hyperplasia Congenita 1 (Dax-1) In Mouse Oogenesis, Krystal Wilson May 2005

The Role Of Dosage Sensitive Sex Reversal Adrenal Hyperplasia Congenita 1 (Dax-1) In Mouse Oogenesis, Krystal Wilson

Renée Crown University Honors Thesis Projects - All

Although critically important to fertility and reproduction, the mechanisms controlling development of mammalian primordial germ cells into functional oocytes are poorly understood. Understanding the mechanisms that regulate oocyte development will ultimately reveal significant insights into female infertility problems in mammals, including humans. In order to decipher what mediates the formation of a functional oocyte, we are studying oogenesis in the mammalian model Mus musculus. During mouse embryonic development the oocytes develop as interconnected clusters of cells called germline cysts. Evidence suggests that in humans, oocytes are also organized into cysts. Eventually the cysts undergo programmed cell breakdown, each giving …

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Essential Kinase-Independent Role Of A Fer-Like Non-Receptor Tyrosine Kinase In Caenorhabditis Elegans Morphogenesis, Aaron P. Putzke May 2005

Essential Kinase-Independent Role Of A Fer-Like Non-Receptor Tyrosine Kinase In Caenorhabditis Elegans Morphogenesis, Aaron P. Putzke

Biology Faculty Scholarship

Morphogenesis requires coordination of cell surface activity and cytoskeletal architecture. During the initial stage of morphogenesis in Caenorhabditis elegans, the concerted movement of surface epithelial cells results in enclosure of the embryo by the epidermis. We report that Fer-related kinase-1 (FRK-1), an ortholog of the mammalian non-receptor tyrosine kinase Fer, is necessary for embryonic enclosure and morphogenesis in C. elegans. Expression of FRK-1 in epidermal cells is sufficient to rescue a chromosomal deficiency that removes the frk-1 locus, demonstrating its autonomous requirement in the epidermis. The essential function of FRK-1 is independent of its kinase domain, suggesting a …

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Developing A Constitutively Active Aryl Hydrocarbon Receptor In The Mouse Heart, Bruno Decaria May 2005

Developing A Constitutively Active Aryl Hydrocarbon Receptor In The Mouse Heart, Bruno Decaria

Renée Crown University Honors Thesis Projects - All

Abstract not Included

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