Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Arts and Humanities

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 6331 - 6360 of 47710

Full-Text Articles in Entire DC Network

Hist 190 Writing & History, Tracey L. Billado Jan 2023

Hist 190 Writing & History, Tracey L. Billado

Open Educational Resources

No abstract provided.


Mental Health Utilization Among Former Pregnant And Parenting Teen Mothers, Chana Danielle Campbell Jan 2023

Mental Health Utilization Among Former Pregnant And Parenting Teen Mothers, Chana Danielle Campbell

Walden Dissertations and Doctoral Studies

Teen pregnancy and parenting at an early age can create numerous emotional stressors. Despite the documented need for mental health services among pregnant and parenting mothers, utilization rates of mental health services remain low. The purpose of this generic qualitative study was to explore the experiences of pregnant and parenting mothers who utilized mental health services. Bandura’s social learning theory was used to explore how the experiences, perceptions, learned behaviors, thoughts, and beliefs surrounding mental health services impacted teen mothers’ experiences with mental health utilization. One-on-one interviews were conducted with eight teen mothers or other young mothers who had given …


African American Women’S Experiences Coping With Stress Through Community-Based Services, Delisa V. Procks Jan 2023

African American Women’S Experiences Coping With Stress Through Community-Based Services, Delisa V. Procks

Walden Dissertations and Doctoral Studies

Few studies have studied how community-based services (CBS) work to mitigate the strong Black woman image (SBWI) coping mechanism for Black women to improve their mental health. The purpose of this generic, qualitative study was to understand the experiences of 10 African American women, ages 18 and older, who identified with the SBWI and had received CBS to address their stress-related coping strategies. Transactional theory of coping with stress and the SBWI approach was used as the framework to help explain how stress in terms of the SBWI impacted the response of the African American women within their environment. Data …


Impact Of Minority Incarceration On The Family Unit, Huey S. Ratcliff Jan 2023

Impact Of Minority Incarceration On The Family Unit, Huey S. Ratcliff

Walden Dissertations and Doctoral Studies

The economic impact of incarceration on minority family units has both secondary and third-order effects on the minority family unit when a family member is incarcerated, which is exacerbated when the incarcerated family member was both the primary breadwinner and a parent. The purpose of this study was to identify the social and economic effects incarceration has on minority families. The study addressed how minority families adjust to changes in organic composition and how the minority family copes with increased debt and loss of earning potential. Further, the study sought to answer how minority families overcome economic hardship when the …


Implementing Music Therapy Into Behavioral Healthcare To Treat Autism Spectrum Disorder, Arthur George Scott Jan 2023

Implementing Music Therapy Into Behavioral Healthcare To Treat Autism Spectrum Disorder, Arthur George Scott

Walden Dissertations and Doctoral Studies

AbstractThis study explored how best to implement Music Therapy (MT) in any hospital setting when working with autistic children, teenagers, and adults. Baldrige’s theory and concepts were used as a benchmark to facilitate all findings through the research conducted. Multiple factors affect the workforce and the existing staff at a large medical facility in the Western United States. The methodology employed included interviews with two behavioral health leaders using structured questions. This was an ideal research setting given that over fifty providers, including doctors, psychiatrists, and therapists, who work daily with the ASD population. Key findings included MT treatments at …


Ash Grove, William Lapage Jan 2023

Ash Grove, William Lapage

Graduate Theses/Dissertations

This thesis presents a collection of poems that attempts to foreground often dismissed or invisible landscapes and the people who inhabit those spaces. Drawing attention to moments of stillness, creating a space for contemplation and reflection, the poems in this collection stitch together a myriad of speakers whose voices grapple with landscapes of the past, interiority, place, and memory. These poems often center on the speaker's interior observations set against an exterior backdrop. These works are informed by the works of Carl Phillips and Robert Lowell, the British poet, Alice Oswald, the German-British painter, Lucian Freud, and the Chilean poet, …


ดุษฎีนิพนธ์การประพันธ์เพลง : “เสียงแห่งแรงบันดาลใจในห้วงภวังค์” สำหรับวงโมเดิร์นอิเล็กทริกอองซอมเบิล, ประทีป เจตนากูล Jan 2023

ดุษฎีนิพนธ์การประพันธ์เพลง : “เสียงแห่งแรงบันดาลใจในห้วงภวังค์” สำหรับวงโมเดิร์นอิเล็กทริกอองซอมเบิล, ประทีป เจตนากูล

Chulalongkorn University Theses and Dissertations (Chula ETD)

บทประพันธ์เพลง “เสียงแห่งแรงบันดาลใจในห้วงภวังค์” สำหรับวงโมเดิร์น อิเล็กทริกอองซอมเบิล มีความยาว 35 นาที ประกอบด้วยเครื่องดนตรีอะคูสติก ได้แก่ ไวโอลินแนวที่ 1 ไวโอลินแนวที่ 2 เชลโล ดับเบิลเบส ฮอร์น เปียโน คีย์บอร์ด กีตาร์ไฟฟ้า ทิมปานีและ ทรัยแองเกิล ผสมด้วยเสียงจากอิเล็กทรอนิกส์ซึ่งถูกสร้างสรรค์โดยผู้วิจัย รูปแบบการประพันธ์แบบอิสระ มีวัตถุประสงค์เพื่อสร้างสรรค์บทประพันธ์เพลงผ่านจินตนาการความฝันเพื่อสะท้อนให้เห็นถึงแนวคิดและการตีความจากสิ่งที่เป็นนามธรรม โดยนำมาถ่ายทอดในลักษณะศิลปะเกี่ยวกับเสียง รวมถึงการศึกษาค้นคว้ารายละเอียดต่าง ๆ ที่เกี่ยวข้องกับความฝัน เช่น ทฤษฎีของซิกมุนด์ ฟรอยด์ คาร์ล ยุง อัลเฟรด แอดเลอร์ คาร์ล กุสตาฟ และคารุส อีกทั้งการวิเคราะห์บทประพันธ์ของคีตกวีที่ได้รับแรงบันดาลใจมาจากความฝันและวิธีการเชื่อมโยงจินตนาการไปสู่ทฤษฎีดนตรี ทฤษฎีเสียง ผู้วิจัยได้ทำการจดบันทึกสิ่ง ต่าง ๆ ที่ปรากฏในความฝัน เช่น สถานที่ อารมณ์ความรู้สึก และวัตถุต่าง ๆ แล้วนำมาสร้างสรรค์เสียงจากการตีความสิ่งเหล่านั้น โดยใช้เทคนิควิธีการที่ได้ศึกษาจากการประพันธ์หลากหลายประเภท ได้แก่ อะคูสติกมิวสิก อิเล็กทรอนิกส์มิวสิก อิเล็กโทรอะคูสติกมิวสิก มิวสิกคอนเคร็ต และซาวด์สเคป นำมาผสมผสานเพื่อให้ได้งานสร้างสรรค์ที่ไร้ขีดจำกัด


Introduction To Contemporary Art Across Political Divides, Alla Myzelev, Tijen Tunali Jan 2023

Introduction To Contemporary Art Across Political Divides, Alla Myzelev, Tijen Tunali

Art History

This book addresses the need for a more sustained knowledge and multidisciplinary understanding of what art and artists can do to create democratic spaces, forms and languages in a world devastated by multiple crises. The book’s main inquiry is whether contemporary art can or cannot cultivate an “agonistic” way of togetherness and facilitate difficult conversations through a multitude of contradictions, diverging views and conflicting visions. With Marxist, feminist and ecologist perspectives, the contributors analyze contemporary art worlds across the globe in relation to memory, conflict, trauma, transitional justice, social engagement, social resistance and activism.

In this volume artists, activists, art …


Spectres Of Women In Wuthering Heights, Corinne H. Shearer Jan 2023

Spectres Of Women In Wuthering Heights, Corinne H. Shearer

Dissertations and Theses

Central to Emily Brontë’s Wuthering Heights (1847) is its famous haunting scene. As this paper suggests, it is in the haunting scene that the novel’s themes are at their most potent and where Brontë is at her most daring, challenging the socially prescribed, gendered binaries of her time. The primary interest of this paper is in describing the particular power of Brontë’s feminine ghost, an archetypal figure of the female Gothic, using theoretical frameworks from poststructuralism and psychoanalysis. I propose a feminist interpretation of the novel which emphasizes the catalyzing effect of the haunting scene and its reversals– and which …


Richard Owen: A Forgotten Icon, Devan Henriott Jan 2023

Richard Owen: A Forgotten Icon, Devan Henriott

Calvert Undergraduate Research Awards

Despite being one of the most famous naturalists of the nineteenth century, Richard Owen is an obscure figure today. This paper delves into how such an influential person to the beginnings of paleontology and biology could have been written out of history. Owen worked his way into the world of comparative anatomy by finding work at the Hunterian Museum. From there, Owen earned respect for his exciting lectures on fossil discoveries and for his research interpreting fossils and reconstructing extinct species. Owen utilized his renown to spread his theories on the creations of species, but mostly kept his evolutionary ideas …


The Other Beginning Of Thinking: Heidegger And Neoplatonism, Emile Alexandrov Jan 2023

The Other Beginning Of Thinking: Heidegger And Neoplatonism, Emile Alexandrov

Theses

This thesis establishes an “other beginning” for thinking by repositioning Plato and Neoplatonism in Heidegger’s history of metaphysics. The thesis achieves this by revising Heidegger’s interpretation of Plato and retrieving Neoplatonist approaches to non-discursive thinking, corresponding to some of Heidegger’s post-turn concerns. The thesis begins by justifying the adoption of Heidegger’s “two beginnings” idea and illustrating what I label the “fundamentals of truth of the first beginning,” which Heidegger used to envision the other beginning of thinking. The fundamentals of truth inform Heidegger’s reading of Hölderlin and the later writings that emerged from the 1950s onwards. The second part re-thinks …


Monstrous Oil: Theorizing Petromodernity's Monsters, Madalynn Lee Madigar Jan 2023

Monstrous Oil: Theorizing Petromodernity's Monsters, Madalynn Lee Madigar

Graduate Student Theses, Dissertations, & Professional Papers

Petroleum, a primary global energy resource, serves as a foundation of our contemporary society. However, the pervasive influence of oil as substance, commodity, and industry in our petromodern lives often goes unrecognized. In the present moment of biogeocultural crisis surrounding fossil fuels, recognizing and understanding our multifaceted engagements with petroleum is critical. This thesis contributes to the growing field of Petrocultural Studies by considering the conceptualization of petroleum through the associated tropes and figure of the monster. Through the petromonstrous, a term that encapsulates the massive scale, haunting effects, and human-other entanglements of petroleum, cultural attitudes and anxieties about oil …


Samozvanets (The Pretender), Matthew Garrell, Alikzandr Malakov Jan 2023

Samozvanets (The Pretender), Matthew Garrell, Alikzandr Malakov

Dartmouth College Master’s Theses

he Russian word Samozvanets most directly translates to Imposter in English. However, for this thesis, I have selected the alternative interpretation of Pretender. Imposter implies the taking or assuming of another’s position. Pretender, more personally, carries the meaning of presenting self as something one is not. It is through the lens of the Pretender that I examine the idea of what it means to be a member of a particular ethnicity, and to engage with one’s cultural heritage. I do this through a collection of fictional stories, investigating various lives within the Russian diaspora following the dissolution of the Soviet …


Ferment, Casey Carpenter Jan 2023

Ferment, Casey Carpenter

Dartmouth College Master’s Theses

The fermentation process – an act of breaking down, letting go, and moving forward – is used by the author as poetic lens and as a narrative tool for self-reflection, self-transformation, cultural reflection, and cultural transformation. Akin to our own adolescent maturation, plants, fruits, and vegetables develop protective barriers around their most vulnerable parts in reaction to the health and condition of their lived environment. While serving a purpose of survival in the moment, these barriers will later cause the food to rot and spoil if left unchecked. The act of fermentation is thus explored as a managed process of …


Machine Learning And Latent Space Representation Of Optical Responses In Nanostructures And Thin Films, David J. Hoxie Jan 2023

Machine Learning And Latent Space Representation Of Optical Responses In Nanostructures And Thin Films, David J. Hoxie

All ETDs from UAB

The ability to tune optical responses in nanophotonics makes this class of materials useful for a broad range of applications, such as drug delivery systems, molecular sensing, green energy, and telecommunications, to name a few. Optical responses that offer strong resonance at small optical mode volume are often sought, requiring manipulation of many material properties i.e., refractive index and nanostructure shape. Machine learning has recently been employed to optimize photonic elements more efficiently. Machine learning optimization of optical responses suffers from reproducibility and accuracy issues due different nanostructures producing similar optical responses. To increase reliability and accuracy in recent neural …


The Association Of Cognitive And Physical Functioning With Health And Mortality Outcomes Among Puerto Ricans, Cheyanne Celine Barba Jan 2023

The Association Of Cognitive And Physical Functioning With Health And Mortality Outcomes Among Puerto Ricans, Cheyanne Celine Barba

All ETDs from UAB

Puerto Rico has experienced a rapid increase in the older adult population over the last decade. With a growing older adult population, the importance of healthy aging becomes increasingly more important to understand. Understanding the impact that impairments in cognitive and physical functioning have on older adults in Puerto Rico will be important to supporting the rapidly aging population. The current project proposed to (1) examine predictors of transition to frailty, (2) examine whether cognitive function and frailty are associated with healthcare utilization, and (3) examine frailty and cognitive impairment as predictors of mortality and Alzheimer’s disease related cause of …


Indicators Of The Social Environment And Cognition In An Older Population Of Puerto Rican Adults, Erin E. Ballard Jan 2023

Indicators Of The Social Environment And Cognition In An Older Population Of Puerto Rican Adults, Erin E. Ballard

All ETDs from UAB

Isolation and other indicators of poor social environment have been associated with a higher risk of cognitive decline. Overall evidence for this association is mixed, with most studies being conducted in Western, educated, industrialized, rich, and democratic (aka “WEIRD”) societies. Religiosity may moderate this relationship between less robust social environments and cognition by buffering the negative effects of stress. The primary aim of this study is to assess the relationship between indicators of the social environment and psychological distress (depressive symptoms) and cognitive decline in a population-based sample of older Puerto Rican adults (n=3,557) across two time-points. Social environment included …


Analyzing Cannabinoid Stability In Different Conditions And Validating Novel Cannabinoids For Oral Fluid Analysis, Cody Paseur Jan 2023

Analyzing Cannabinoid Stability In Different Conditions And Validating Novel Cannabinoids For Oral Fluid Analysis, Cody Paseur

All ETDs from UAB

Oral fluid (OF) drug testing has been expanded to laboratory evidentiary confirmation testing in driving under the influence (DUI) cases. OF samples are collected by officers at the roadside using collection devices such as the Quantisal® device. Tetrahydrocannabinol (Δ9-THC) was the most prevalent drug in Alabama DUI casework in 2022. Δ9-THC remains a Schedule I drug in Alabama and federally. Current validated targets in cannabinoid oral fluid testing include Δ9-THC, Δ8-THC, 9R-Δ10-THC, 9S-Δ10-THC 11-hydroxy-Δ9-THC (THC-OH), 11-nor-9-carboxy-Δ9-THC (THC-OOH), cannabigerol (CBG), cannabidiol (CBD), and cannabinol (CBN). Due to the 2018 Farm Bill, cannabinoids derived from hemp with a Δ9-THC concentration less than …


Development And Validation Of A Multiplex Str Amplification Reaction For Academic And Research Purposes, Ahana Chatterjee Jan 2023

Development And Validation Of A Multiplex Str Amplification Reaction For Academic And Research Purposes, Ahana Chatterjee

All ETDs from UAB

Short Tandem Repeat (STR) typing has been accepted globally as a gold standard for human identity testing. In 1997, the Federal Bureau of Investigation (FBI) Laboratory’s newly developed Combined DNA Index System (CODIS) consisted of 13 core loci to be targeted while DNA typing. In this context, leading biotechnology companies like Promega (Madison WI), Applied Biosystem/Life Technologies (Foster City, CA) etc. offer commercial STR typing kits for crime laboratories. However, these expensive kits are not the most suitable for academic and research laboratories. Students learning the method of STR typing and researchers showing proof of concept do not require identifying …


Accuracy Of Ancestry Estimation In Forensic Anthropology: An Examination Of Select Nonmetric Methods, Mackenzie Miller Jan 2023

Accuracy Of Ancestry Estimation In Forensic Anthropology: An Examination Of Select Nonmetric Methods, Mackenzie Miller

All ETDs from UAB

A goal of forensic anthropology is to aid in identifying unidentified human remains, often by creating a biological profile. An important piece of this profile is an ancestry estimate, and methodological accuracy is taken seriously. Traditional typological nonmetric methods of ancestry are heavily critiqued for being subjective and lacking scientific rigor in analysis. In addition, these methods are noted for conflating morphological traits with specific ancestral categories, ignoring the reality of continuous human variation. To combat this, scholars have proposed morphoscopic nonmetric methods as an alternative because they retain the accessibility popularized by typological methods but add a layer of …


Increasing Naloxone Access For Persons Who Use Opioids: An Online Recruitment And Training Approach To Opioid Overdose Education And Naloxone Distribution, Michelle L. Sisson Jan 2023

Increasing Naloxone Access For Persons Who Use Opioids: An Online Recruitment And Training Approach To Opioid Overdose Education And Naloxone Distribution, Michelle L. Sisson

All ETDs from UAB

Drug overdose is the primary cause of accidental death in the United States, with a majority of those fatalities involving opioids. Annual rates of fatal opioid overdoses have exponentially increased over the past two decades, leading to the declaration of the current opioid epidemic. The severity of the epidemic has increased due to an upsurge in the use of heroin, synthetic opioids (e.g., fentanyl), and the lacing of other substances with synthetic opioids. As such, federal agencies have made recommendations aimed at combating fatal opioid overdose including the enhancement of naloxone distribution. Administration of naloxone has been expanded from emergency …


Unveiling The Unknown Rna-Binding Landscape Of Srsf1, Naiduwadura Ivon Upekala De Silva Jan 2023

Unveiling The Unknown Rna-Binding Landscape Of Srsf1, Naiduwadura Ivon Upekala De Silva

All ETDs from UAB

SRSF1 is a prototypical SR protein and its interactions with single stranded RNA (ssRNA) are crucial in mRNA splicing. Its RNA-binding specificity is governed by the RNA-binding Domain (RBD), which contains two RNA Recognition Motifs (RRMs) tethered by a flexible linker. Its C-terminal unstructured Serine-Arginine-rich (RS) domain has been believed to bind RNA non-specifically so far. Although SRSF1 is known to bind a variety of RNA containing its RRM-cognate motifs, its interactions with such RNA have been poorly characterized. Therefore, we explore how SRSF1 achieves a broad RNA-binding specificity ranging from ssRNA to G-quadruplex (GQ) RNA. According to our Fluorescence …


The Er Stress-Pathogen Nexus In Regulation Of Cell Death In Arabidopsis Immunity, Danish Diwan Jan 2023

The Er Stress-Pathogen Nexus In Regulation Of Cell Death In Arabidopsis Immunity, Danish Diwan

All ETDs from UAB

Pathogens and plants are involved in a coevolutionary battle for dominance. As plants lack adaptive immune systems, they rely on their innate immunity to protect themselves from infectious agents. Upon pathogen attack, plant cells activate their pro-survival strategy by recognizing the pathogen and actively transcribing and translating proteins to effectively defend against the pathogen infection. As the intensity of infection increases, the heightened demand for proteins places an excessive burden on the ER machinery resulting in the accumulation of misfolded or unfolded proteins within the ER. To restore the protein homeostasis, a cellular relief signaling pathway called Unfolded Protein Response …


Investigation Of Reversibility And Nucleotide Effects In The Kinetic Mechanisms Of Nucleotide Addition In The Eukaryotic Rna Polymerases, Kaila B. Fuller Jan 2023

Investigation Of Reversibility And Nucleotide Effects In The Kinetic Mechanisms Of Nucleotide Addition In The Eukaryotic Rna Polymerases, Kaila B. Fuller

All ETDs from UAB

Eukaryotes utilize at least three multi-subunit DNA dependent RNA polymerases (Pol I, II, and III) to synthesize RNA. The Pols are similar in structure but have distinct kinetic mechanisms that describe nucleotide addition. The product of Pol I synthesis, ribosomal RNA (rRNA) comprises the majority of the ribosome and is necessary for gene expression. Despite the importance of Pol I transcription in the cell, there is still much to understand about the roles of specific subunits in Pol I and the different factors that affect the kinetic mechanism of nucleotide addition catalyzed by Pol I. Our group has previously published …


Transdiagnostic Symptom Clusters Among Idiopathic Pain And Fatigue Disorders, Chloe Lisette Jones Jan 2023

Transdiagnostic Symptom Clusters Among Idiopathic Pain And Fatigue Disorders, Chloe Lisette Jones

All ETDs from UAB

Background: There are no established etiologies, biomarkers, or approved treatments for myalgicencephalomyelitis/chronic fatigue syndrome (ME/CFS). It is thought that the ME/CFS criteria may be diagnosing individuals within a spectrum of different disease states, or even different diseases. There likely exist shared mechanisms across idiopathic pain and fatigue disorders, and diverse mechanisms underneath each individual diagnosis. The need to compare ME/CFS to similar, overlapping, and distinct disorders is a critical element in progressing our understanding of idiopathic pain and fatigue. Methods: A total of 2,731 comprehensive medical history and symptom reports were collected from respondents across the globe with a variety …


Physiology And Energetics Of Resilient Coral-Dinoflagellate Communities, Elise F. Keister Jan 2023

Physiology And Energetics Of Resilient Coral-Dinoflagellate Communities, Elise F. Keister

All ETDs from UAB

Despite coral reefs declining globally, thermally resilient coral-dinoflagellate communities have been identified, providing insight into how corals can inhabit warmer environments. These corals are able to better resist and recover from thermal stress events compared to adjacent, offshore conspecifics that are found in habitats that have cooler temperatures. To better understand the physiological traits that make corals resilient, I measured the initial tissue biomass and energy reserves of eight coral species. These corals were collected from both warm-water nearshore habitats and offshore reefs with milder temperatures in Palau, Micronesia. Despite contrasting environments, coral tissue similarities between these populations were striking, …


Examining The Impact Of The Covid-19 Pandemic And Subsequent Vaccine Availability On Children’S Social Play Opportunities With A Focus On The Autism Community, Jenni Koehler Jan 2023

Examining The Impact Of The Covid-19 Pandemic And Subsequent Vaccine Availability On Children’S Social Play Opportunities With A Focus On The Autism Community, Jenni Koehler

All ETDs from UAB

Play, especially social play, is crucial to child development and impacts their cognitive, socioemotional, and motor growth. Children with an autism spectrum disorder (ASD) have social and motor impairments that act as barriers to their access to these critical social play opportunities. Those who are able to overcome these barriers through therapy have been shown to have better physical and mental outcomes. Unfortunately, the COVID-19 pandemic restricted social play opportunities for all children and disproportionately impacted children with ASD, further widening developmental gaps between them and their non-autistic peers. The development of the COVID-19 vaccine and its availability to children …


Role Of Gtp Cyclohydrolase I In Glioblastoma, Kaysaw C. Tuy Jan 2023

Role Of Gtp Cyclohydrolase I In Glioblastoma, Kaysaw C. Tuy

All ETDs from UAB

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with a median survival of 15 months. Poor patient survival is, in part, caused by a stem-like and therapy-resistant population of brain tumor initiating cells (BTICs). BTICs are plastic, with the capacity to overcome oxidative damage. Guanosine triphosphate cyclohydrolase I (GCH1), a rate limiting enzyme in the de novo synthesis of the redox cofactor, tetrahydrobiopterin (BH4), was previously identified as a significant regulator of oxidative stress in BTICs. Reducing oxidative damage in the form of lipid peroxidation is imperative for GBM growth: lipid metabolism is required for the …


The Influence Of Economic Disadvantage On The Health And Well-Being Of Youth Transitioning To Adulthood, Shanquela Williams Jan 2023

The Influence Of Economic Disadvantage On The Health And Well-Being Of Youth Transitioning To Adulthood, Shanquela Williams

All ETDs from UAB

Young adults transitioning to adulthood from economically disadvantaged backgrounds may experience physical, cognitive, and socio-emotional challenges. Resources and opportunities available during this transition can significantly impact their ability to integrate into society. The impact of economic disadvantage on the well-being of youth transitioning to adulthood remains understudied. The purpose of this study was to understand how economic disadvantage influenced the well-being of youth transitioning into adulthood. This project used longitudinal data from the Panel Study of Income Dynamics (PSID) and its supplements: the Child Development Supplement (CDS) and the Transition into Adulthood Supplement (TAS). Hypothesis one results revealed that young …


Production, Purification And Radiochemistry Development Of Manganese-52 Fir Characterization Of Pet/Mr Imaging Agents, Jennifer Marie Pyles Jan 2023

Production, Purification And Radiochemistry Development Of Manganese-52 Fir Characterization Of Pet/Mr Imaging Agents, Jennifer Marie Pyles

All ETDs from UAB

Manganese (Mn) has the potential to be an important element in biomedical research as different isotopes of Mn have the characteristics to be used for both positron emission tomography (PET) and magnetic resonance imaging (MRI). Manganese(II) (55Mn) is paramagnetic which makes it useful as a contrast agent in T1-weighted magnetic resonance imaging (MRI). Mn as a radiotracer provides excellent sensitivity for studying 55Mn, but only Manganese-52 (52Mn) met the criteria for this research. 52Mn has a half-life (t1/2 = 5.591 days) that was long enough to optimize purification, chemistry and examine timepoints over several days. 52Mn decays by positron emission …