Digital Commons Network^™

N-Thiolated Β-Lactams: Chemistry, Sar And Intracellular Target Of A Novel Class Of Antimicrobial And Anticancer Agents, Bart Allan Heldreth

USF Tampa Graduate Theses and Dissertations

N-Thiolated β-lactams (1) represent a promising new group of compounds with potent inhibition effects on bacteria, like Bacillus anthracis and methicillin resistant Staphylococcus aureus, and onco-systems, like breast cancer and leukemia. Originally developed as part of a synthetic pathway to bicyclic lactams, N-thiolated β-lactams have been shown in this laboratory to possess intriguing biological activities. The antibacterial activities of this new class of agents rely on novel structural features unlike those of any existing family of β-lactam drugs. The lactams seem to exert their effects intracellularly, requiring passage of the bioactive species through the cellular …

Examining The Current U.S. Beef Trade Policies Concerning The Testing For Mad Cow Disease, David C. Miller

USF Tampa Graduate Theses and Dissertations

Despite existing mad cow disease surveillance efforts in the United States, in place since the 1980s, a cow that tested positive for mad cow disease was granted entrance into the U.S. in December, 2003. The cow that tested positive, according to witnesses, displayed no symptoms that are synonymous with advanced bovine spongiform encephalopathy, BSE. This occurrence had detrimental effects on the U.S. beef export market, as many countries banned American beef. Estimates of the damage inflicted reach into the billions of dollars. BSE in the U.S. has the potential of causing damages in other aspects as well. Aside from the …

The Stress Response, Psychoeducational Interventions And Assisted Reproduction Technology Treatment Outcomes: A Meta-Analytic Review, Karen Rose Mumford

USF Tampa Graduate Theses and Dissertations

The psychological impacts of infertility have been well documented in the literature, providing evidence to support that at least some women who confront infertility are at risk for heightened distress and depressive symptoms. In response to this accumulated evidence, it has been argued that psychoeducational interventions may provide an important component to the treatment of infertility. While several theoretical models postulate the effects of stress on infertility treatment outcomes, results of these investigations have led to conflicting conclusions. However, a synthesis of the accumulated data examining the effects of stress on ART treatment outcomes was nonexistent until the conduct of …

Socio-Cultural, Environmental And Health Challenges Facing Women And Children Living Near The Borders Between Afghanistan, Iran And Pakistan (Aip Region), Iraj M. Poureslami, David R. Maclean, Jerry Spiegel, Annalee Yassi

Journal of International Women's Studies

For hundreds of years, people in the AIP region (the Afghanistan-Iran-Pakistan borders) have been challenged by conflict and political and civil instability, mass displacement, human rights abuses, drought and famine. Given this sad history, it not surprising that in this region health and quality of life of vulnerable groups are among the worst in the world. In spite of national and international efforts to improve health status of vulnerable populations in this region, the key underlying socio-cultural determinants of health and disparities, i.e. gender, language, ethnicity, residential status, and socio-economic status (SES), have not been addressed or even systematically studied, …

A Heuristic Methodology For Locating Monitoring Stations To Detect Contamination Events In Potable Water Distribution Systems, James R. Chastain Jr.

USF Tampa Graduate Theses and Dissertations

The requirements to protect public water systems from intentional contamination have expanded in the years following September 11, 2001. The areal extent and non-linear nature of water demand and movement in the distribution system makes efficient location of sampling points difficult. This difficulty is compounded by the fact that contamination conceptually can occur at any point and at any time within the distribution system. Small to mid-sized water systems are especially at a disadvantage in addressing this issue due to limited resources available to them.

This paper proposes a heuristic methodology to identify strategic locations within the system that can …

Felix Platter: A Sixteenth-Century Medical Student, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

No abstract provided.

Oncolog, Volume 49, Number 09, September 2004, Ellen Mcdonald, Ann Sutton, David Galloway, Rena Sellin Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• New Approaches to Managing Tumors of the Pituitary Gland Offer Patients Hope
• Needleless Chemotherapy: Safety and Efficacy of Aerosolized Chemotherapy Being Studied in Young Patients with Cancer
• M. D. Anderson Physician Honored for Inventing an Antimicrobial Catheter That Prevents 25,000 Infection-Related Deaths a Year
• House Call: How Cancer Happens and Ways to Lower Your Risk
• DiaLog: Cancer-Related Neuroendocrine Dysfunction, by Rena V. Sellin, MD, Professor, Department of Endocrine Neoplasia and Hormonal Disorders

Agribusiness Sheep Updates - 2004 Part 2, Anyou Liu, Clinton Revell, Phil Nichols, Brad Nutt, Darryl Clements, Lucy Anderton, Stephen Gherardi, Chris Oldham, Paul Sanford, John Gladman, G. E. Donald, A. Edirisinghe, D. A. Henry, S. P. Gittins, R. C. G. Smith, Roy Butler, Kelly Pearce, David Masters, David Pethick, Andrew Thompson, Ken Hart, Johan Greeff, Beth Paganoni, Rachel Kirby, Matt Ryan, Kira Butler, Roger Heggarty, David Hopkins, Samantha Giles, Tom Plaisted, Mark Ferguson, Darren Gordon, John Young, Sandra Brown, Ian Mcfarland, John Archer, John Milton, Rob Davidson, Graeme Martin, David Lindsay, Johnathan England, Mandy Curnow, Karina P. Wood, Ashley K. White, B. Lloyd Davies, Paul M. Carberry, Mark Hyder, Mike Freer, Andrew Van Burgel, Kazue Tanaka, Andrew Peterson, Roger Wiese, Gonzalo Mata, Evan Burt, Amanda Miller, Anne Bennett, Felicity Flugge, Amir Abadi, Perry Dolling, Dean Thomas, Mike Ewing, David Lindsay, Emma Kopke, E. A. Dowling, E. K. Crossley, Brien (Ben) E. Norton, John Karlsson, Geoff Pollott, Diana Fedorenko, Darryl Clements, Robert Beard, Brown Besier, Una Ryan, Caroline Bath

Sheep Updates

Precision Pastures

Using Species Diversity to Improve Pasture Performance Anyou Liu and Clinton Revell, Department of Agriculture, Western Australia

New Annual Pasture Legumes for Sheep Graziers Phil Nichols, Angelo Loi, Brad Nutt and Darryl McClements Department of Agriculture Western Australia

Pastures from Space – Can Satellite Estimates of Pasture Growth Rate be used to Increase Farm Profit? Lucy Anderton, Stephen Gherardi and Chris Oldham Department of Agriculture Western Australia

Summer-active Perennial Grasses for Profitable Sheep Production Paul Sanford and John Gladman, Department of Agriculture, Western Australia

Pastures From Space – Validation Of Predictions Of Pasture Growth Rates DONALD, G.E^{.A …}

Agribusiness Sheep Updates - 2004 - Part 1, Mark Dolling, Len Stephens, David Thomanson, Norm Adams, Shimim Liu, Peter Buchman, Mike Paton, Dianne Evans, John Edwards, Scott Champion, Alan Langford, A. C. Schlink, J. C. Greeff, M. E. Ladyman, Kimbal M. S. Curtis, John Stanton, Stuart Adams, Neal Fogarty, Matthew Kelly, James Skerritt, Ian Mcfarland

Sheep Updates

Proceedings of the Agribusiness Sheep Updates - 2004 Forward Dr Mark Dolling Manager, Sheep Industries and Pasture, Department of Agriculture Western Australia Keynotes Australian Wool Innovation Limited DR LEN STEPHENS AUSTRALIAN WOOL INNOVATION LIMITED (AWI) Commercialisation of Sheepmeat Eating Quality Outcomes, David Thomason, General Manger Marketing Meat & livestock Australia Limited PLENARY The Fitness of the Future Merino, Norm Adams and Shimin Liu, CSIRO Livestock Industries Ovine Johne’s Disease – Managing the Disease, Managing the Issues, PETER BUCKMAN, CHIEF VETERINARY OFFICER, DEPARTMENT OF AGRICULTURE WESTERN AUSTRALIA Animal Welfare – Changes in Latitudes Changes in Attitudes, Michael Paton and Dianne Evans, …

Detection, Cloning, And Analysis Of A U32 Collagenase In Streptococcus Mutans Gs-5, Marios Ioannides

USF Tampa Graduate Theses and Dissertations

Streptococcus mutans is a recognized principal etiologic agent in coronal caries. Although S. mutans has the ability to bind collagen and degrade FALGPA, a synthetic peptide mimicking collagen substrate, its role in dental root caries has not yet been fully elucidated. Degradation of collagen fibrils in dentin was attributed to S. mutans, but a collagenase enzyme has not yet been isolated from this organism. Considering the increased incidence of dental root decay among the elderly, an understanding of the role of the pathogenic factors is necessary to the development of preventive measures. The present study has focused on the …

The Quality Of Life Among Lymphedema Patients Due To Lymphatic Filariasis In Three Rural Towns In Haiti, Koji Kanda

USF Tampa Graduate Theses and Dissertations

The worldwide eradication of lymphatic filariasis has recently started with two strategies, interruption of transmission and morbidity control. One of the most endemic countries, Haiti has experienced successful interventions through national and international efforts, but the morbidity control is still hindered by a lack of adequate information on quality of life (QOL) issues among those suffering from the chronic manifestations of the disease such as lymphedema. In addition, previous interventions have been focused primarily in a single community where an established lymphedema treatment clinic serves as a national reference center, so it is critical to expand programs to other areas …

Jefferson Alumni Bulletin – Volume 53, Number 3, June 2004

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 53, Number 3, June 2004 Robert L. Barchi MD PhD Is Named President of Thomas Jefferson University; Page 4 The Importance of Mentors: David's Story by Dean Thomas J. Nasca ’75; Page 6 The Center for Human Virology: Confronting the Whole Spectrum of Epidemics; Page 8 Jefferson Selected to Develop Response to Bioterrorism; Page 10 Four Students Win AOA Community Service Award; Page 11 Stories from Iraq and Afghanistan; Page 12 New Book about the Nationally Recognized Physician Shortage Area Program; Page 16

Implications Of Biblical Principles Of Rhythm And Rest For Individual And Organizational Practices, Margaret Diddams, Lisa Surdyk, Denise Daniels, Jeff B. Van Duzer

SPU Works

The information technology economy with its endless 24/7 workdays has eroded the normative cycle of work and rest, and as a result, many Americans are experiencing a profound and increasing sense of time pressure. By integrating biblical passages relating to Sabbath observance with psychological and organizational empirical literature, Diddams et al seek describe the principles of rest, reflection, and relationships underlying biblical notions of rhythm; identify their associated influence on psychological wellness; and discuss how organizations can embrace a rhythmic, Sabbath culture.

Risk Factors For Pediatric Community Acquired Methicillin Resistant Staphylococcus Aureus, Melissa Gail Kessler

USF Tampa Graduate Theses and Dissertations

Methicillin-Resistant Staphylococcus aureus (MRSA) began as a nosocomial infection due to overuse of antibiotics. Several previous studies have reported an increase in this infection in adult patients who have not been hospitalized. It has also been reported that there is an increase in MRSA in children. Some of these children became infected even though they were not at high risk for the infection. After approval from the All Children's Hospital Institutional Review Board (IRB), a cross sectional study was conducted with pediatric admissions and pediatric emergency room visits to determine the characteristics of Methicillin-Sensitive Staphylococcus aureus and MRSA. During this …

Fur Trade Daughters Of The Oregon Country: Students Of The Sisters Of Notre Dame De Namur, 1850, Shawna Lea Gandy

Dissertations and Theses

Ethnicity, religion, class, and gender are important elements in determining the cultural texture of society. This study examines these components at an important junction in the history of the Pacific Northwest through the lives of students enrolled in two girls' schools established by the Sisters of Notre Dame de Namur (SNDN) in the Willamette Valley in the 1840s. These girls, predominantly métis daughters of fur-trade settlers and their Indian wives, along with their Irish and Anglo-American classmates, represent the socioeconomic and cultural transformation of the region as the mixing that gave rise to the unique intermediary culture referred to as …

2004 Celebration Of Inquiry Program, Coastal Carolina University

Celebration of Inquiry

3rd Celebration of Inquiry, February 11-13, 2004. Theme: Seeing the World Anew

[Review Of] Plagues & Poxes: The Impact Of Human History On Epidemic Disease [By] Alfred Jay Bollet, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

No abstract provided.

Social And Behavioral Aspect Of Mother’S Health Behaviors And Neonatal Health: Risk Factor Analysis Of Neonatal Septicemia In Urban Slums Of Muntinlupa, Philippines, Chisaki Sato

USF Tampa Graduate Theses and Dissertations

Reducing neonatal mortality can contribute to the further reduction of infant mortality rates in international health as it is responsible for about half of the mortality rate for those underfive today. The situation of infant mortality in the Philippines is no exception to this global trend. This study of the social demographic aspects of sepsis neonatorum in the Philippines has explored the conditions of the urban environment, and local cultures related to newborn illnesses and the patterns of health seeking behaviors of urban poor mothers which can affect the survival of newborns. The mix of qualitative and quantitative research methods …

Studies On Antibacterial Activities Of N-Thiolated Β-Lactams And Their Polymeric Nanoparticles Against Mrsa, Jeung-Yeop Shim

USF Tampa Graduate Theses and Dissertations

Methicillin-resistant Staphylococcus Aureus (MRSA) is now the most challenging bacterial pathogen affecting patients in hospitals and in care centers, and has brought on the need to develop new drugs for MRSA. This thesis centers on studies of N-thiolated β-lactams, a new family of potent antibacterial compounds that selectively inhibit the growth of methicillin-resistant Staphylococcus aureus (MRSA).

Chapter 1 describes MRSA in more detail. Chapter 2 outlines experiments on the effect of a fatty ester group (CO₂R) on the C₄-phenyl ring of N-methylthio β-lactams, expecting that attachment of long chain ester moieties might increase the hydrophobicity, …

Comida Sin Frijoles No Es Comida: Evaluation Of A Type 2 Diabetes Education Program For Latinos, Danielle R. O'Connor

USF Tampa Graduate Theses and Dissertations

This thesis describes an internship for the Department of Anthropology that was part of the Florida Health Literacy Study (FHLS) conducted at the University of South Florida College of Public Health, Department of Community and Family Health in the spring and summer of 2003. The FHLS implemented Pfizer Inc.'s For Your Health program, a type 2 diabetes and hypertension education programs, at 14 community health clinics across the state of Florida. The internship was designed to elicit the experiences of 10 bilingual health educators about their experiences and their perceptions of the experiences of their Latino patients with type 2 …

Congruence Among Mathematics Skills Used On The Job By Practical Nurses Vs. The Prerequisite Skills Required For Admission Into The Practical Nursing Program, G H. Clary

USF Tampa Graduate Theses and Dissertations

The standard for evaluating a student's mathematic ability (grade level) for admission to many vocational-technical programs is through the administration of the Tests of Adult Basic Education (TABE). There has come forth a concern from vocational educators, that students entering programs may not be prepared for the mathematics required by the curriculum, even though the student has met the criteria for entry as established by the state curriculum frameworks as evidenced by their scores on a TABE which had recently been administered. Furthermore, questions raised among instructional, administrative and guidance personnel about the congruence of math skills required on the …

Ada News - 10/04/2003, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Longhunter, Southern Kentucky Genealogical Society Newsletter Volume 26, Number 4, Kentucky Library Research Collections

Longhunter, Southern Kentucky Genealogical Society Newsletter

No abstract provided.

The Passion Of Edith Stein, Freda Mary Oben

Providence: Studies in Western Civilization

No abstract provided.

The Benefits Of Breastfeeding: An Introduction For Health Educators, Sheila G. J. Clark, Timothy J. Bungum

Environmental & Global Health Faculty Research

Currently 16% of Americans breastfeed their children for at least 12 months as recommended by the AAP, which is well below the HP 2010 goal of 25%. Breastfed infants receive benefits that can improve their health throughout their lives. The benefits of breastfeeding for children include increased resistance to infectious diseases, such as gastroenteritis, respiratory tract infections, and ear infections. Breastfed children also display lower rates of chronic diseases including diabetes, obesity, asthma, and leukemia. The choice to breastfeed results in economic benefits from lower health care costs and from reduced spending on infant formula. The Healthy People 2010 targets …

Eng 1001g-041: Composition And Language, Ned Huston

Fall 2003

No abstract provided.

Eng 1001g-070: Composition And Language, Ned Huston

Fall 2003

No abstract provided.

Eng 1001g-062: Composition And Language, Ned Huston

Fall 2003

No abstract provided.

Bioterrorism Syndromic Surveillance: A Dual-Use Approach With Direct Application To The Detection Of Infectious Disease Outbreaks, Kristin Broome Uhde

USF Tampa Graduate Theses and Dissertations

The threat of bioterrorism forces the public health infrastructure to focus attention on overall issues related to challenges posed by emerging and re-emerging infectious diseases. There is a crucial need to strengthen existing surveillance systems and to validate real-time approaches to surveillance that can provide timely alerts of epidemics whether they occur naturally or through a bioterrorism attack. The purpose of this study is to implement and evaluate a bioterrorism syndromic surveillance system called BioDefend™, to determine if the system could detect a potential epidemic/bioterrorism attack within 24-36 hours, more rapidly than it would be identified by routine health surveillance. …

Ua68/13/4 Limited Edition, Wku Journalism

WKU Administration Documents

Newspaper created by students participating in the Minority Journalism Workshop hosted by the WKU Journalism Department.

• Clark, Ashlee. Campus Security Tightens in Wake of Murder
• Lau, Jessica. Diversity Grows, Problems Persist
• Yee, April. Home of Love
• Leong, Jennifer. State Street Baptist Church Rededication Date Set
• Cowherd, Heather. Growing Up Black in Bowling Green
• Clark, Ashlee & Aja Junior. Regents Approve Increased Budget
• Leong, Jennifer. Hispanic Ministry Provides Heartfelt Worship
• Taylor, Sean. Shake Rag Gains New Support, Awareness
• Taylor, Sean. Patriot Act Tramples Peoples' Civil Rights
• Clark, Ashlee. Got Ethics?
• Winters, Jonathan. Remove Patriotism from Flames
• Yee, April. Stereotypes
• Jefferson, Regina …