Digital Commons Network^™

Training Set Augmentation And Harmonization Enables Radiomic Models To Detect Early Onset Of Lung Cancer, Claire Huchthausen, Menglin Shi, Gabriel L.A. Sousa, James Larner, Einsley Janowski, Jonathan Colen, Krishni Wijesooriya

Data Science Faculty Publications

Radiomics-based machine learning models have the potential to detect lung cancer at inception from CT scans and transform patient outcomes. Low malignancy rates in early-development pulmonary nodules (PNs) and variable image acquisition hinder development of clinically applicable radiomics-based early detection models. To address these challenges, we augmented training using later-development PNs and harmonized for acquisition effects. We first trained machine learning models to predict PN malignancy using radiomic features from scans of early-development benign and malignant PNs (n = 187) harmonized using ComBat. Observing near-chance performance, we augmented training with later-development benign and malignant PNs (n = 225). We evaluated …

Advancing Pedagogical And Instructional Design Through Artificial Intelligence (Ai) In Education And Training Contexts, Mohan Yang, Jewoong Moon, Tian Luo, Jinhee Kim

STEMPS Faculty Publications

[Introduction] "The only way to discover the limits of the possible is to go beyond them into the impossible." - Arthur C. Clarke

It is our pleasure and honor as guest editors for this special issue of the Journal of Applied Instructional Design (JAID) to present "Advancing Pedagogical and Instructional Design through Artificial Intelligence (AI) in Education and Training Contexts." This issue arrives at a truly timely moment, as the rapid and continuous development of generative artificial intelligence (GenAI) is fundamentally reshaping the traditional paradigms of teaching, learning, and training.

A Bibliometric Analysis Of Ai-Driven Healthcare Literature Containing Kos Keywords: Trends, Themes, And Gaps, Julaine Clunis, Eric Asare

STEMPS Faculty Publications

As artificial intelligence (AI) becomes increasingly embedded in healthcare applications, concerns have emerged around the trustworthiness, interpretability, and context-awareness of these systems. Knowledge Organization Systems (KOS) hold considerable potential to address these challenges by supporting semantic standardization, explainability, and domain alignment. This study presents a bibliometric analysis of scholarly publications referencing both AI and healthcare concepts to examine how KOS are positioned within this evolving discourse. The findings indicate that while early literature frequently and explicitly referenced KOS—such as ontologies, controlled vocabularies, and classification systems—their visibility has declined relative to newer paradigms such as machine learning and large language models. …

Understanding Physiological Responses For Intelligent Posture Detection Using Wearable Technology, Chaitanya Vardhini Anumula, Tanvi Banerjee, Anuradha Oak

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

This study investigates the physiological impact of Iyengar yoga at the pose-level using EmbracePlus wearable smartwatch, for data recording and personalized yoga pose detection for tracking.

Overcoming Resistance To Ai In Higher Education: A Case Study, C. Tomovic, M. Tomovic

Educational Leadership & Workforce Development Faculty Publications

While the deployment of AI in business and industry is widely acknowledged for its potential to improve efficiencies, decision-making, and automation, its implementation often encounters several challenges. These include integrating AI with existing systems, ensuring data quality and availability, bridging the employee skills gap, overcoming resistance to change, addressing ethical concerns, managing costs, complying with regulations, and handling ongoing maintenance and updates. In the context of higher education, however, the challenges take a different shape. Faculty members may express concerns about how AI could disrupt traditional teaching methods, necessitate changes in course delivery, and raise issues related to job security …

Towards Dynamic Learner State: Orchestrating Ai Agents And Workplace Performance Via The Model Context Protocol, Mohan Yang, Nolan Lovett, Belle Li, Zhen Hou

Educational Leadership & Workforce Development Faculty Publications

Current learning and development approaches often struggle to capture dynamic individual capabilities, particularly the skills they acquire informally every day on the job. This dynamic creates a significant gap between what traditional models think people know and their actual performance, leading to an incomplete and often outdated understanding of how ready the workforce truly is, which can hinder organizational adaptability in rapidly evolving environments. This paper proposes a novel dynamic learner-state ecosystem—an AI-driven solution designed to bridge this gap. Our approach leverages specialized AI agents, orchestrated via the Model Context Protocol (MCP), to continuously track and evolve an individual’s multi-dimensional …

The Reliability Response To Patent Law’S Ai Challenges, Arti K. Rai

Faculty Scholarship

Pervasive AI use adds newfound importance to longstanding debates over patent timing and reliability. Patent claims on speculative ideas generated by AI, or even the infusion of speculative AI-generated ideas into the public domain, may defeat patent incentives for more careful research. Although challenges that AI use poses for patent validity requirements like human inventorship and nonobviousness have received more attention, reliability is equally important.

Indeed, as this Article argues, the issues are linked. If requirements for inventorship and nonobviousness were adjusted to emphasize reliability, a human role could be preserved, and AI use would not necessarily threaten patents. Currently, …

Information Retrieval In The Age Of Generative Ai: A Mismatch That Matters, Alex Zhang

Faculty Scholarship

This short piece explores a widespread and yet underexamined or even overlooked misconception, that is, large language models (LLMs) function like traditional legal research databases. They do not. As a matter of fact, information retrieval from databases functions very differently from LLMs in terms of inputs, retrieval processes, and outputs. These differences have significant implications for transparency, traceability, and overall effectiveness in AI-driven legal research. Without intentional oversight and adaption, these changes could profoundly affect how we develop research skills and a cumulative knowledge base, both of which are essential skills for lifelong learning in the legal field.

This article …

A Retrieval Augmented Approach To Improving Accuracy Of Biomedical Term Normalization By Large Language Models, Thanh Son Do

Graduate Theses/Dissertations

Ontology normalization is crucial in biomedical text processing, as it enables the mapping of medical expressions to standardized ontology terms and their corresponding identifiers. This thesis explores the feasibility of using large language models (LLMs) for ontology normalization, with a specific focus on the Human Phenotype Ontology and Gene Ontology. Prior research studies indicated that LLMs employing zero-shot learning tend to exhibit low accuracy and are prone to frequent hallucinations. We propose a retrieval augmented generation (RAG) approach to address these limitations and enhance normalization accuracy. We generated synthetic test sets of ontology-derived synonyms to evaluate normalization performance and developed …

Efficient Task Scheduling In Cloud Infrastructures Using Dynamic Score-Based Allocation And Deep Q-Learning, Shadman Sakib

Graduate Theses/Dissertations

Cloud computing has grown rapidly in recent years, mainly due to the sharp increase in data transferred over the internet. This growth makes task scheduling a key and challenging part of cloud systems, as it helps distribute user requests across servers to minimize response time, prevent overloading, and ensure smooth user experience. This thesis proposes two novel approaches for dynamic task scheduling in cloud environments. First, a novel Score-Based Dynamic Load Balancing (SBDLB) strategy is developed, which leverages system parameters to allocate tasks efficiently across virtual machines (VMs) in data centers. SBDLB ensures balanced workload distribution by continuously evaluating VM …

Topology-Guided Adaptive Social Navigation For A Robot In Environments With Dynamic Obstacles, S.M. Faiaz Mursalin

Graduate Theses/Dissertations

Robotic navigation in dynamic environments presents significant challenges, particularly in managing interactions with moving obstacles while ensuring efficient path planning. Incorporating social navigation principles is crucial as robots share the same workspaces with humans frequently in daily life. This becomes essential for safe, efficient, and socially acceptable movements. In this thesis, I introduce a novel integration of social navigation strategies with topological path planning that leverages Discrete Morse Theory, a homotopical framework to enhance adaptability. My method dynamically assesses path feasibility and optimizes trajectory selection through three key strategies: waiting, deflection, and diverse path selection. Based on how close the …

Reinforcement Learning For Scheduling And Routing: Electric Vehicles Charging And Patrol Scheduling, Majid Ghasemi

Theses and Dissertations (Comprehensive)

This thesis offers a comprehensive exploration of Reinforcement Learning (RL), beginning with fundamental theoretical constructs, Markov Decision Processes, Dynamic Programming, Monte Carlo, and Temporal Difference methods, and extending into state-of-the-art deep RL approaches such as Deep Q-Networks (DQN) and policy-gradient algorithms. Through analytical experiments in controlled environments, the thesis demonstrates how distinct algorithmic choices (e.g., exploration techniques, eligibility traces, or network architectures) influence convergence and stability. These foundational insights pave the way for two in-depth case studies, which apply RL techniques to critical, real-world scheduling and routing challenges.

The first case study tackles the Electric Vehicle (EV) routing and charging …

A Two-Phase Learning Approach Integrated With Multi-Source Features For Cloud Service Qos Prediction, Fuzan Chen, Jing Yang, Haiyang Feng, Harris Wu, Minqiang Li

Information Technology & Decision Sciences Faculty Publications

Quality of Service (QoS) is a key factor for users when choosing cloud services. However, QoS values are often unavailable due to insufficient user evaluations or provider data. To address this, we propose a new QoS prediction method, Multi-source Feature Two-phase Learning (MFTL). MFTL incorporates multiple sources of features influencing QoS and uses a two-phase learning framework to make effective use of these features. In the first phase, coarse-grained learning is performed using a neighborhood-integrated matrix factorization model, along with a strategy for selecting high-quality neighbors for target users. In the second phase, reinforcement learning through a deep neural network …

A Spoofing Speech Detection Method Combining Multi-Scale Features And Cross-Layer Identification, Hongyan Yuan, Linjuan Zhang, Baoning Niu, Xianrong Zheng

Information Technology & Decision Sciences Faculty Publications

Pre-trained self-supervised speech models can extract general acoustic features, providing feature inputs for various speech downstream tasks. Spoofing speech detection, which is a pressing issue in the age of generative AI, requires both global information and local features of speech. The multi-layer transformer structure in pre-trained speech models can effectively capture temporal information and global context in speech, but there is still room for improvement in handling local features. To address this issue, a speech spoofing detection method that integrates multi-scale features and cross-layer information is proposed. The method introduces a multi-scale feature adapter (MSFA), which enhances the model’s ability …

Investing In The Age Of Generative Ai: A Gpt-Based Sentiment Analysis Approach, Xianrong Zheng

Information Technology & Decision Sciences Faculty Publications

Generative AI, which ushers a new age of AI, comes with huge economic potential. To capitalize the AI boom, investors are interested in trading AI stocks. AI chatbots, which can identify and classify the sentiment from financial news, can be leveraged for investment. So, this paper proposes a GPT-based sentiment analysis approach for trading AI stocks. Also, natural experiments are conducted to evaluate its effectiveness. Initial results show that the approach achieves a good rate of return.

High Tech Touts, Sherman J. Clark

Articles

This essay has three interrelated aims. First, it articulates a set of capacities I call virtues of attention—capacities for intuitive discernment, good judgment about what is worth sustained focus, and the ability to engage deeply with worthwhile things. These are eudaimonist virtues in that they help us live well, not merely act rightly. Second, the essay explores what I call poisonous persuasion: the idea that rhetorical appeals, especially those used in marketing, may not only succeed by appealing to certain desires or habits of mind but may also deepen and entrench them. Third, I bring these insights together to examine …

Do Specialized Medical Llms Demand A Radically New Approach Under The Eu's Medical Device Regulation, Hannah Louise Smith, W. Nicholson Price Ii

Articles

We examine the arguments made by Onitiu and colleagues concerning the need to adopt a “backward-walking logic” to manage the risks arising from the use of Large Language Models (LLMs) adapted for a medical purpose. We examine what lessons can be learned from existing multi-use technologies and applied to specialized LLMs, notwithstanding their novelty, and explore the appropriate respective roles of device providers and regulators within the ecosystem of technological oversight.

Boden Lecture: Taxation Of Autonomous Artificial Intelligence, Reuven S. Avi-Yonah, Lucas Brasil Salama, Herbert Snitz, W. Robert Thomas

Articles

This Article proposes that tax can be a useful supplement to other measures to regulate Autonomous Artificial Intelligence (AAI) and limit its potential harmful effects. This proposal differs from command-and-control regulation of AAI along the lines of European Union legislation that may unduly limit the development of AAI. It also differs from existing proposals to tax AAI to generate revenue to help workers displaced by AAI programs, or to tax the data used by AAI The proposal is based on granting AAI programs like ChatGPT separate legal personhood, like corporate personhood, while incentivizing or requiring their corporate owner to place …

Synthetic Data Generation Of Health And Demographic Surveillance Systems Data: A Case Study In A Low- And Middle-Income Country, Dorcas G. Mwigereri, Nigel T. Kamotho, Akbar K. Waljee, Ryan T. Rego, Eileen M. Weinheimer-Haus, Farhana Alarakhiya, Anthony K. Ngugi, W. Nicholson Price, Ji Zhu, Stephen Peter Wong, Geoffrey H. Siwo

Articles

Objective: To evaluate effectiveness of open-source generative models in producing high-quality tabular synthetic data using a Health and Demographic Surveillance System (HDSS) dataset from rural Kenya, as a proof of concept in a low- and middle-income (LMIC) setting.

Materials and Methods: Three open-source models (CTGAN, TableGAN, and CopulaGAN) were used to generate synthetic data from the Kaloleni/ Rabai HDSS dataset. To assess the quality of the synthetic datasets generated by each model, we performed fidelity, utility, and privacy tests.

Results: CTGAN outperformed the other models, producing synthetic data that closely mirrored the statistical properties of the real dataset while preserving …

The Future Of Ai Regulation In Drug Development: A Comparative Analysis, Gabriela Lenarczyk, Timo Minssen, W. Nicholson Price Ii, Arti Rai

Articles

As artificial intelligence (AI) transforms drug development, regulatory frameworks are evolving to oversee its implementation, particularly at the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). This paper makes three contributions to understanding emerging regulatory approaches. First, we offer a comparative analysis of how these agencies have responded to AI-driven advances, incorporating new US executive orders and the European Union (EU)’s AI Act. Second, we propose a novel analytical framework to understand regulatory divergence: the FDA’s flexible, dialog-driven model contrasts with the EMA’s structured, risk-tiered approach, reflecting broader institutional and political-economic differences. While the former encourages …

Empirical Assessment Of Cybersecurity Competencies Through Human-Generative Artificial Intelligence (Genai) Teaming, Dariusz Witko

CCAC Theses and Dissertations

The critical shortage of skilled cybersecurity professionals, with over 750,000 unfilled positions in the United States (U.S.), combined with rising practitioner burnout and the complexity of modern cyber threats, poses significant risks to national security. As Generative Artificial Intelligence (GenAI) emerges as a potential tool to support cybersecurity operations, its role in assisting human analysts with high-demand tasks offers both opportunities and challenges. While GenAI can improve efficiency, it also introduces adversarial risks if manipulated by malicious actors. This study investigated how human-GenAI collaboration can address these challenges, focusing on the fundamental cybersecurity knowledge, skills, and task completion required for …

Development Of An Ecg-Based Deep Learning Model For Pediatric Congenital Heart Disease (Chd) Diagnosis, Annbar Mekouar

Selected Full-Text Master Theses 2021-

Congenital heart disease (CHD) stands as the leading congenital anomaly which affects pediatric populations throughout the world. The effectiveness of treatment depends on both early diagnosis and accurate identification but echocardiography requires manual interpretation which proves time-consuming and inconsistent especially when examining pediatric patients with their distinct cardiac systems. The research aims to create a deep learning-based diagnostic framework which uses ECG data to identify coronary artery disease subtypes in pediatric patients. The model uses high-quality datasets from Dr. Ignacio Lugones to extract R-R intervals and QRS durations through convolutional neural networks (CNNs). The system addresses pediatric-specific challenges while enhancing …

Strategic Identification Of Prognostic Biomarkers For Knee Osteoarthritis Via Optimized Regression Techniques, Varun Sri Sai Vemuri

Selected Full-Text Master Theses 2021-

Knee Osteoarthritis (KOA) is a progressive musculoskeletal disease involving cartilage matrix degradation, subchondral bone remodeling, and systemic inflammation, significantly impairing joint function and mobility. Existing KOA prediction models are not designed to account for nonlinear multimodal biomarker interactions or to integrate biochemical and imaging data, thus limiting their clinical utility. The current method for early detection and prediction of KOA disease progression is primarily based on machine learning-based approaches using radiographic imaging data, static feature selection, and deterministic outputs. These machine learning approaches often fail to capture the pathophysiology of KOA disease progression, which involves a complex cascade of processes, …

Applying Transfer Learning For Street-Scale Nuisance Flood Forecasting In Coastal-Urban Cities, Binata Roy, Jonathan L. Goodall, Diana Mcspadden, Chetan Kumar, Steven Goldenberg, Yidi Wang, Malachi Schram

VMASC Publications

An important challenge with Machine Learning (ML) is its transferability; i.e., whether a ML model trained on one set of data can be applied to a second set of data without requiring full re-training of the model. Transfer Learning (TL) addresses this challenge by transferring knowledge learned in the source domain (the data it was trained on) to the target domain (a second set of data that is statistically different but related, which the model was not trained on). This study investigates the use of TL for street-scale nuisance flood forecasting by exploring whether a ML model trained for one …

Faithful Narratives From Complex Conceptual Models: Should Modelers Or Large Language Models Simplify Causal Maps, Tyler J. Gandee, Philippe J. Giabbanelli

VMASC Publications

(1) Background: Comprehensive conceptual models can result in complex artifacts, consisting of many concepts that interact through multiple mechanisms. This complexity can be acceptable and even expected when generating rich models, for instance to support ensuing analyses that find central concepts or decompose models into parts that can be managed by different actors. However, complexity can become a barrier when the conceptual model is used directly by individuals. A ‘transparent’ model can support learning among stakeholders (e.g., in group model building) and it can motivate the adoption of specific interventions (i.e., using a model as evidence base). Although advances in …

The Importance Of Atomic Charges For Predicting Site-Selective Ir-, Ru-, And Rh-Catalyzed C-H Borylations, Shannon M. Stephens, Kyle M. Lambert

Chemistry & Biochemistry Faculty Publications

A supervised machine learning model has been developed that allows for the prediction of site selectivity in late-stage C-H borylations. Model development was accomplished using literature data for the site-selective (≥95%) C-H borylation of 189 unique arene, heteroarene, and aliphatic substrates that feature a total of 971 possible sp² or sp³ C-H borylation sites. The reported experimental data was supplemented with additional chemoinformatic descriptors, computed atomic charges at the C-H borylation sites, and data from parameterization of catalytically active tris-boryl complexes resulting from the combination of seven different Ir-, Ru-, and Rh-based precatalysts with eight different ligands. Of the over …

Predictive Maintenance In Naval Vessel Propulsion Systems For Enhanced Marine Operations Using A Bigmm-Hmm Framework With Divergence-Based Clustering, Farshid Javadnejad, Hyoshin John Park, Samuel Kovacic, Andres Sousa-Poza

Engineering Management & Systems Engineering Faculty Publications

This study introduces a BiGMM-HMM Integration Framework designed to improve predictive maintenance strategies for naval vessel propulsion systems, addressing the need for efficient and reliable operation in marine engineering applications. The framework effectively manages multimodal sensor data by leveraging a unique combination of Gaussian Mixture Models (GMMs) and Hidden Markov Models (HMMs) in a bidirectional architecture. It analyses the dynamic interactions between sensors and subsystems. Two preprocessing methods are evaluated: Method 1 focuses on subsystem interactions, employing divergence-based root cause analysis to identify key sensor variables by clustering of sensors and subsystems. In contrast, Method 2 processes the entire dataset …

Optimizing Port Logistics Through Generative Ai: Revolutionizing Efficiency And Resilience In The Maritime Industry, Minodora Badea, Olga Bucovetchi, Adrian V. Gheorghe, Gabriel Raicu

Engineering Management & Systems Engineering Faculty Publications

The maritime industry faces growing challenges in optimizing port logistics due to increasing trade volumes, environmental regulations, and supply chain disruptions. This comprehensive literature review examines the transformative role of artificial intelligence (AI), with particular focus on generative AI, in enhancing efficiency and resilience in port operations. Through systematic analysis of 23 peer-reviewed studies published between 2021-2025, this review synthesizes advancements in real-time data integration, machine learning, digital twins, IoT, and autonomous systems that collectively improve operational decision-making, risk management, and environmental sustainability. Key findings reveal that machine learning applications achieve 90% effectiveness ratings in operational optimization, while predictive analytics …

Comprehensive Benchmarking Of Several Machine Learning And Bayesian Models For Early-Stage Diabetes Risk Prediction: A Large-Scale Comparative Study, Md. Iqbal Hossain, Najila Alam Porno

Mathematics & Statistics Faculty Publications

Diabetes remains a critical global health challenge, with early detection is crucial for effective management. This study presents a comprehensive benchmarking analysis of 14 diverse machine learning and Bayesian models for early-stage diabetes risk prediction using clinical data [2] from Sylhet, Bangladesh. This research evaluated traditional methods (Logistic Regression, Decision Trees), ensemble techniques (Random Forest, XGBoost, LightGBM), Bayesian approaches (BART, Bayesian Logistic Regression), and advanced neural architectures (Deep Belief Networks) using both 70-30 train-test splits and 10-fold cross-validation. The results demonstrate that ensemble methods consistently outperformed other approaches, with Random Forest(RF) achieving the highest cross-validated AUC (0.9951) and accuracy (0.9699). …

Novel Generative And Language Model Architectures With Applications, Edison Mucllari

Theses and Dissertations--Mathematics

This dissertation investigates novel architectures to address fundamental challenges in machine learning, particularly focusing on transformer models, recurrent neural networks, GAN and continual learning and their applications in natural language processing and computer vision. We propose the Neumann-Cayley Gated Recurrent Unit (NC-GRU), which leverages a Neumann series-based Scaled Cayley transformation to maintain orthogonal weight matrices, effectively mitigating exploding gradients problems while improving long-term memory retention across prediction tasks. We demonstrate the practical applications of NC-GRU by implementing our proposed architecture into an autoencoder to derive neural molecular fingerprints. Building upon these advancements, we turn our attention to the transformer architecture, …