Social and Behavioral Sciences Commons^™

Effects Of Dexamethasone On Posterior Capsule Opacification-Like Changes In A Rat Lens Explant Model, Kylie Mansfield, Anna Cerra, Coral Chamberlain

Faculty of Science, Medicine and Health - Papers: part A

Purpose: Many patients whose sight is initially restored by cataract surgery eventually suffer secondary loss of vision because of posterior capsule opacification (PCO; after-cataract), a condition in which lens epithelial cells left behind at surgery become aberrant and migrate into the light path. The aim of this study was to determine whether dexamethasone (DEX), an anti-inflammatory agent widely used before and after cataract surgery, influences the behavior of lens cells under conditions relevant to PCO development.

Methods: An established rat PCO model was used in which explanted epithelial cells attached to the lens capsule are exposed sequentially to TGFβ2 and …

Birth Parents And The Reunification Process: A Study Of The Mendocino County Model, Laura Frame, Amy Conley Wright, Jill Duerr Berrick

Faculty of Social Sciences - Papers (Archive)

The purpose of this study is to closely examine key services offered by the Mendocino County Family Service Center (MCFSC), in order to better understand the change process for birth parents in the child welfare system, their service needs, and the potential usefulness of the MCFSC model in meeting those needs. In particular, the study sought to examine the role of the Intake and Empowerment groups, to identify the key components of the group interventions that appeared to facilitate a change process for birth parents; and give voice to the experience of birth parents with respect to this change process …

Smoothing With Mixed Model Software, Long Ngo, M P. Wand

Faculty of Engineering and Information Sciences - Papers: Part A

Smoothing methods that use basis functions with penalization can be formulated as fits in a mixed model framework. One of the major benefits is that software for mixed model analysis can be used for smoothing. We illustrate this for several smoothing models such as additive and varying coefficient models for both S-PLUS and SAS software. Code for each of the illustrations is available on the Internet.

On The Transferability Of The Spcal Water Model To Biomolecular Simulation, Alice Glaettli, Chris Oostenbrink, Xavier Daura, Daan Geerke, Haibo Yu, Wilfred Van Gunsteren

Faculty of Science - Papers (Archive)

We investigated the performance of the recently developed SPC/L model for liquid water, as a pure liquid, in binary mixtures with DMSO, and as a solvent model in a peptide folding simulation. Additionally, in order to test the compatibility with the GROMOS biomolecular force field, free energies of hydration of a set of representative compounds were computed. The results are compared to those for the well established SPC water model, which is generally used as a solvent model in conjunction with the GROMOS force field already for more than two decades. It turns out that as a pure liquid and …