Open Access. Powered by Scholars. Published by Universities.®

Social and Behavioral Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

High

Michael L.F. Lerch

Articles 1 - 3 of 3

Full-Text Articles in Social and Behavioral Sciences

The Feasibility Study And Characterziation Of A Two-Dimensional Diode Array In “Magic Phantom” For High Dose Rate Brachytherapy Quality Assurance, A Espinoza, B Beeksma, M Petasecca, I Fuduli, C Porumb, D L. Cutajar, S Corde, M A. Jackson, M Lf Lerch, Anatoly B. Rosenfeld Nov 2013

The Feasibility Study And Characterziation Of A Two-Dimensional Diode Array In “Magic Phantom” For High Dose Rate Brachytherapy Quality Assurance, A Espinoza, B Beeksma, M Petasecca, I Fuduli, C Porumb, D L. Cutajar, S Corde, M A. Jackson, M Lf Lerch, Anatoly B. Rosenfeld

Michael L.F. Lerch

High dose rate (HDR) brachytherapy is a radiation treatment technique capable of delivering large dose rates to the tumor. Radiation is delivered using remote afterloaders to drive highly active sources (commonly 192Ir with an air KERMA strength range between 20 000 and 40 000 U, where 1 U = 1 uGy m2/h in air) through applicators directly into the patient's prescribed region of treatment. Due to the obvious ramifications of incorrect treatment while using such an active source, it is essential that there are methods for quality assurance (QA) that can directly and accurately verify the treatment plan and the …


A Real-Time In Vivo Dosimetric Verification Method For High-Dose Rate Intracavitary Brachytherapy Of Nasopharyngeal Carcinoma, Zhen-Yu Qi, Xiao-Wu Deng, X Cao, Shao-Min Huang, Michael Lerch, Anatoly Rosenfeld Nov 2013

A Real-Time In Vivo Dosimetric Verification Method For High-Dose Rate Intracavitary Brachytherapy Of Nasopharyngeal Carcinoma, Zhen-Yu Qi, Xiao-Wu Deng, X Cao, Shao-Min Huang, Michael Lerch, Anatoly Rosenfeld

Michael L.F. Lerch

Purpose: A real-time in vivo dosimetric verification method using metal-oxide-semiconductor field effect transistor (MOSFET) dosimeters has been developed for patient dosimetry in high-dose rate (HDR) intracavitary brachytherapy of nasopharyngeal carcinoma (NPC). Methods: The necessary calibration and correction factors for MOSFET measurements in 192Iridium source were determined in a water phantom. With the detector placed inside a custom-made nasopharyngeal applicator, the actual dose delivered to the tumor was measured in vivo and compared to the calculated values using a commercial brachytherapy planning system. Results: Five MOSFETs were independently calibrated with the HDR source, yielding calibration factors of 0.48 ± 0.007 cGymV. …


Performance Comparison Of Two Compact Multiplexed Readouts With Sensl's Spmarray4 For High-Resolution Detector Module, Yujin Qi, Xiaohui Zhang, Cuilan Zhao, Lihong Chen, Marco Petasecca, Mitra Safavi-Naeini, Michael Lerch, Anatoly Rosenfeld Nov 2013

Performance Comparison Of Two Compact Multiplexed Readouts With Sensl's Spmarray4 For High-Resolution Detector Module, Yujin Qi, Xiaohui Zhang, Cuilan Zhao, Lihong Chen, Marco Petasecca, Mitra Safavi-Naeini, Michael Lerch, Anatoly Rosenfeld

Michael L.F. Lerch

The purpose of this study was to investigate a compact readout for silicon photomultiplier (SiPM) array in the development of high-resolution imaging detector to reduce the readout channels while maximizing the detectors performance. The detector module was composed of a LYSO scintillation crystal array and a SensL's SPMArray4. The crystal array was coupled to the SiPM array with a 2mm-thick silicone pad to improve the light sharing among the SiPM array elements. Three LYSO crystal arrays of 4x4, 8x8 and 12x12 crystal elements with pixel sizes of 3.2, 1.6 and 1.0 mm were investigated in this study. Two compact multiplexed …