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Case Report: Survival After Deliberate Strychnine Self-Poisoning, With Toxicokinetic Data, David Michael Wood, Emma Webster, Daniel Martinez, Paul Ivor Dargan, Alison L. Jones

Faculty of Science, Medicine and Health - Papers: part A

Introduction Strychnine poisoning is uncommon, and in most severe cases, the patient dies before reaching hospital. The management of strychnine poisoning is well documented, although there are few data on the kinetics of elimination of strychnine after overdose. Case report A 42-year-old man presented shortly after ingestion of an unknown quantity of strychnine powder. After a respiratory arrest, with intensive supportive management requiring admission to an intensive care unit, he survived. Eight serum samples were taken over the first 5 days and analysed subsequently for strychnine concentrations. Results The initial concentration at 1.5 hours after ingestion was 4.73 mg/l, falling …