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Articles 1 - 30 of 62
Full-Text Articles in Social and Behavioral Sciences
Stress Profile Influences Learning Approach In A Marine Fish, Vincent Raoult, Larissa Trompf, Jane E. Williamson, Culum Brown
Stress Profile Influences Learning Approach In A Marine Fish, Vincent Raoult, Larissa Trompf, Jane E. Williamson, Culum Brown
Culum Brown, PhD
The spatial learning skills of high and low stress juvenile mulloway (Argyrosomus japonicus) were tested in a dichotomous choice apparatus. Groups of fish were formed based on background blood cortisol levels and required to learn the location of a food reward hidden in one of two compartments. Low stress fish characterised by low background levels of the stress hormone cortisol had higher activity levels and entered both rewarded and unrewarded rooms frequently. Within the first week of exposure, however, their preference for the rewarded room increased, indicative of learning. Fish that had high background levels of cortisol, in …
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
John Copeland Nagle
This study was commissioned by the Hawkesbury-Nepean (HNCMA), Sydney Metropolitan (SMCMA) and Southern Rivers (SRCMA) Catchment Management Authorities and undertaken by the University of Wollongong to collate existing data and to provide a preliminary assessment of the potential impacts of coal seam gas (CSG) and coal mining activities on environmental assets within the three CMA regions, where environmental assets were defined under three broad themes; water, land and biodiversity. This study formed part of the Australian Federal Government’s Department of Sustainability, Environment, Water, Population and Communities (SEWPaC) Bioregional Assessment initiative within regions potentially affected by CSG and coal mining activities. …
Pace: A Group Randomised Controlled Trial To Increase Children's Break-Time Playground Physical Activity, Anne-Maree Parrish, Anthony D. Okely, Marijka Batterham, Dylan P. Cliff, Christopher A. Magee
Pace: A Group Randomised Controlled Trial To Increase Children's Break-Time Playground Physical Activity, Anne-Maree Parrish, Anthony D. Okely, Marijka Batterham, Dylan P. Cliff, Christopher A. Magee
Dr Marijka Batterham
Abstract presented at Be Active 2014, 15-18 October 2014, Canberra, Australia.
Improved Workflow Modelling Using Role Activity Diagram-Based Modelling With Application To A Radiology Service Case Study, Nagesh Shukla, John Keast, Darek Ceglarek
Improved Workflow Modelling Using Role Activity Diagram-Based Modelling With Application To A Radiology Service Case Study, Nagesh Shukla, John Keast, Darek Ceglarek
Nagesh Shukla
The modelling of complex workflows is an important problem-solving technique within healthcare settings. However, currently most of the workflow models use a simplified flow chart of patient flow obtained using on-site observations, groupbased debates and brainstorming sessions, together with historic patient data. This paper presents a systematic and semi-automatic methodology for knowledge acquisition with detailed process representation using sequential interviews of people in the key roles involved in the service delivery process. The proposed methodology allows the modelling of roles, interactions, actions, and decisions involved in the service delivery process. This approach is based on protocol generation and analysis techniques …
A Survey Of Martian Dust Devil Activity Using Mars Global Surveyor Mars Orbiter Camera Images, Jenny A. Fisher, Mark I. Richardson, Claire E. Newman, Mark A. Szwast, Chelsea Graf, Shabari Basu, Shawn P. Ewald, Anthony D. Toigo, R. John Wilson
A Survey Of Martian Dust Devil Activity Using Mars Global Surveyor Mars Orbiter Camera Images, Jenny A. Fisher, Mark I. Richardson, Claire E. Newman, Mark A. Szwast, Chelsea Graf, Shabari Basu, Shawn P. Ewald, Anthony D. Toigo, R. John Wilson
Jenny A Fisher
A survey of dust devils using the Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) wide- and narrow-angle (WA and NA) images has been undertaken. The survey comprises two parts: (1) sampling of nine broad regions from September 1997 to July 2001 and (2) a focused seasonal monitoring of variability in the Amazonis region, an active dust devil site, from March 2001 to April 2004. For part 1, dust devils were identified in NA and WA images, and dust devil tracks were identified in NA images. Great spatial variability in dust devil occurrence is highlighted, with Amazonis Planitia being the …
The Effect Of Elbow Flexion Speed And Partial Limb Occlusion On Emg Activity, John Sampson, Herbert Groeller, Darryl Mcandrew, R Achttien, J Stege
The Effect Of Elbow Flexion Speed And Partial Limb Occlusion On Emg Activity, John Sampson, Herbert Groeller, Darryl Mcandrew, R Achttien, J Stege
Darryl J McAndrew
This investigation aimed to determine the neuromuscular response of the bicep brachii during heavy (6RM) dynamic resistance exercise performed to volitional exhaustion. Electromyographic (EMG) activity was compared in twelve male subjects performing dominant-limb elbow flexion exercise during four conditions: i) Explosive concentric and eccentric (SSC); ii) Explosive concentric, control eccentric (EC); iii) control (C); and iv) control with limb occlusion (CO) (110mmHg). CO and SSC are reported to increase motor unit activity when compared to control exercise (2 second flexion, 2 second extension). It was hypothesised that EMG activity will be higher in conditions of explosive exercise. Surface EMG activity …
Emg Activity And Total Work Reduction In Occluded And Non-Occluded Resistance Exercise Conditions, John Sampson, Herbert Groeller, Darryl Mcandrew, Heath Kilah
Emg Activity And Total Work Reduction In Occluded And Non-Occluded Resistance Exercise Conditions, John Sampson, Herbert Groeller, Darryl Mcandrew, Heath Kilah
Darryl J McAndrew
No abstract provided.
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
Samuel K Marx
This study was commissioned by the Hawkesbury-Nepean (HNCMA), Sydney Metropolitan (SMCMA) and Southern Rivers (SRCMA) Catchment Management Authorities and undertaken by the University of Wollongong to collate existing data and to provide a preliminary assessment of the potential impacts of coal seam gas (CSG) and coal mining activities on environmental assets within the three CMA regions, where environmental assets were defined under three broad themes; water, land and biodiversity. This study formed part of the Australian Federal Government’s Department of Sustainability, Environment, Water, Population and Communities (SEWPaC) Bioregional Assessment initiative within regions potentially affected by CSG and coal mining activities. …
Anti-Cancer Activity Of An Acid-Labile N-Alkylisatin Conjugate Targeting The Transferrin Receptor, Vineesh Indira Chandran, Lidia Matesic, Julie Locke, Danielle Skropeta, Marie Ranson, Kara Vine
Anti-Cancer Activity Of An Acid-Labile N-Alkylisatin Conjugate Targeting The Transferrin Receptor, Vineesh Indira Chandran, Lidia Matesic, Julie Locke, Danielle Skropeta, Marie Ranson, Kara Vine
Danielle Skropeta
We have previously reported a series of pH-sensitive imine-linked N-alkylisatin prodrugs that are stable at pH 7.4, but readily cleaved at pH 4.5. Herein, one of the most potent prodrugs, 5,7-dibromo-N-(pmethoxybenzyl) isatin (NAI), was functionalized with a para-phenylpropionic acid linker, and the resulting NAI–imine prodrug conjugated to transferrin (Tf) to form a NAI–imine–Tf conjugate. Cytotoxicity assays revealed the conjugate was equipotent to the free drug against MCF-7 breast cancer cells, with clear selectivity patterns based on TfR levels. These results suggest that this novel isatin-based cytotoxin conjugated to a tumor targeting protein via an acid-labile linker warrants further preclinical testing.
The Effect Of Individual N-Glycans On Enzyme Activity, Danielle Skropeta
The Effect Of Individual N-Glycans On Enzyme Activity, Danielle Skropeta
Danielle Skropeta
No abstract provided.
Synthesis And Anti-Leukaemic Activity Of Pyrrolo[3,2,1-Hi]Indole-1,2- Diones, Pyrrolo[3,2,1-Ij]Quinoline-1,2-Diones And Other Polycyclic Isatin Derivatives, Lidia Matesic, Julie M. Locke, Kara Vine, Marie Ranson, John B. Bremner, Danielle Skropeta
Synthesis And Anti-Leukaemic Activity Of Pyrrolo[3,2,1-Hi]Indole-1,2- Diones, Pyrrolo[3,2,1-Ij]Quinoline-1,2-Diones And Other Polycyclic Isatin Derivatives, Lidia Matesic, Julie M. Locke, Kara Vine, Marie Ranson, John B. Bremner, Danielle Skropeta
Danielle Skropeta
To further expand the structure–cytotoxic activity relationships of isatin derivatives and to reduce flexibility in substituent groups at nitrogen, 20 analogues incorporating a ring system between the N1 and C7 atoms of isatin were prepared using a variety of synthetic strategies. This yielded pyrroloindole-, pyrroloquinoline-, pyrroloacridine-, pyrrolophenanthridine- and benzopyrrolophenanthridine-based systems with embedded isatin moieties, the latter possessing a novel carbon skeleton. These compounds were subsequently assessed for their in vitro cytotoxicity against human U937 lymphoma cells, with the brominated pyrroloacridine dione 27 showing the most promising activity (IC50 3.01 μM) after 24 h.
C-Amp Dependent Protein Kinase A Inhibitory Activity Of Six Algal Extracts From South Eastern Australia And Their Fatty Acid Composition, Ana Zivanovic, Danielle Skropeta
C-Amp Dependent Protein Kinase A Inhibitory Activity Of Six Algal Extracts From South Eastern Australia And Their Fatty Acid Composition, Ana Zivanovic, Danielle Skropeta
Danielle Skropeta
c-AMP dependent protein kinase (protein kinase A, PKA) is an important enzyme involved in the regulation of an increasing number of physiological processes including immune function, cardiovascular disease, memory disorders and cancer. The objective of this study was to evaluate the PKA inhibitory activity of a range of algal extracts, along with their fatty acid composition. Six algal species were investigated including two Chlorophyta (Codium dimorphum and Ulva lactuca), two Phaeophyta (Phyllospora comosa and Sargassum sp.) and two Rhodophyta (Prionitis linearis and Corallina vancouveriensis), with the order of PKA inhibitory activity of their extracts identified as follows: brown seaweeds > red …
Phytochemical And Biological Activity Studies Of The Bhutanese Medicinal Plant Corydalis Crispa, Phurpa Wangchuk, Paul A. Keller, Stephen G. Pyne, Thanapat Sastraruji, Malai Taweechotipatr, Roonglawan Rattanajak, Aunchalee Tonsomboon, Sumalee Kamchonwongpaisan
Phytochemical And Biological Activity Studies Of The Bhutanese Medicinal Plant Corydalis Crispa, Phurpa Wangchuk, Paul A. Keller, Stephen G. Pyne, Thanapat Sastraruji, Malai Taweechotipatr, Roonglawan Rattanajak, Aunchalee Tonsomboon, Sumalee Kamchonwongpaisan
Paul Keller
The chemical constituents and biological activities of Corydalis crispa (Fumariaceae) were investigated for the first time. The phytochemical study resulted in the isolation of nine known isoquinoline alkaloids: protopine (1), 13-oxoprotopine (2), 13-oxocryptopine (3), stylopine (4), coreximine (5), rheagenine (6), ochrobirine (7), sibiricine (8) and bicuculline (9), with complete NMR data for 2 and 3 provided here for the first time. Crude extracts exhibitedsignificant anti-inflammatory (p < 0.01) activity against TNF-alpha production in LPS activated THP-1 cells. The acetylcholinesterase inhibitory activity of compounds 2, 4 and 7 and the antiplasmodial activity of compound 5 against P. falciparum strains TM4/8.2 and K1CB1 …
Baseline Characteristics Of Volunteers In The Smart Clinical Trial: Associations Between Habitual Physical Activity And Lifestyle Disease Risk Factors, Qingsheng Zhang, Jane E. O'Shea, Rebecca L. Thorne, Linda C. Tapsell, Marijka Batterham, Karen E. Charlton
Baseline Characteristics Of Volunteers In The Smart Clinical Trial: Associations Between Habitual Physical Activity And Lifestyle Disease Risk Factors, Qingsheng Zhang, Jane E. O'Shea, Rebecca L. Thorne, Linda C. Tapsell, Marijka Batterham, Karen E. Charlton
Qingsheng Zhang
Physical Activity has been suggested to have favorable effects on various cardiovascular risk factors, and may serve as an intervening variable in life-style intervention studies. We aimed to examine the relationship between habitual physical activity and selected cardiovascular markers at baseline in a sample of overweight women who participated in the SMART clinical trial [ACTRN12608000425392]. A sub-sample of eighty-six overweight/obese women (mean age ± S.D.: 45 ± 7.9 years) were included in this analysis. Anthropometric and fasting blood data was collected at baseline (t = 0). Habitual physical activity was assessed by a validated questionnaire (Baecke questionnaire). Associations were examined …
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
Solomon Buckman Dr.
This study was commissioned by the Hawkesbury-Nepean (HNCMA), Sydney Metropolitan (SMCMA) and Southern Rivers (SRCMA) Catchment Management Authorities and undertaken by the University of Wollongong to collate existing data and to provide a preliminary assessment of the potential impacts of coal seam gas (CSG) and coal mining activities on environmental assets within the three CMA regions, where environmental assets were defined under three broad themes; water, land and biodiversity. This study formed part of the Australian Federal Government’s Department of Sustainability, Environment, Water, Population and Communities (SEWPaC) Bioregional Assessment initiative within regions potentially affected by CSG and coal mining activities. …
The Influence Of The Social Context On Students In-Class Physical Activity, Dana J. Perlman
The Influence Of The Social Context On Students In-Class Physical Activity, Dana J. Perlman
Dana Perlman
The purpose of this study was to examine the influence of the social context, based within self-determination theory, on student's in-class physical activity. A total of 84 Year 11/12 physical education students were randomly assigned to one of three treatment groups; Autonomy-supportive, Controlling and Balanced. Data were collected using a pretest/posttest design measuring in-class physical activity. Analysis of data used Repeated Measures ANOVAs to examine group differences. Results indicated significant differences for students engaged in the autonomy-supportive context in terms of moderate-to-vigorous physical activity. These results indicate that instructional behaviors that align with an autonomy-supportive context can facilitate higher levels …
Replication Termination In Escherichia Coli: Structure And Anti-Helicase Activity Of The Tus-Ter Complex, Cameron Neylon, Andrew V. Kralicek, Thomas M. Hill, Nicholas E. Dixon
Replication Termination In Escherichia Coli: Structure And Anti-Helicase Activity Of The Tus-Ter Complex, Cameron Neylon, Andrew V. Kralicek, Thomas M. Hill, Nicholas E. Dixon
Professor Nick E Dixon
The arrest of DNA replication in Escherichia coli is triggered by the encounter of a replisome with a Tus protein-Ter DNA complex. A replication fork can pass through a Tus-Ter complex when traveling in one direction but not the other, and the chromosomal Ter sites are oriented so replication forks can enter, but not exit, the terminus region. The Tus-Ter complex acts by blocking the action of the replicative DnaB helicase, but details of the mechanism are uncertain. One proposed mechanism involves a specific interaction between Tus-Ter and the helicase that prevents further DNA unwinding, while another is that the …
Declining Physical Activity Levels As An Unintended Consequence Of Abolishing Mandatory Campus Service Fees, Sandra C. Jones, Lance R. Barrie
Declining Physical Activity Levels As An Unintended Consequence Of Abolishing Mandatory Campus Service Fees, Sandra C. Jones, Lance R. Barrie
Sandra Jones
Objective: This study investigates the effect of the introduction of voluntary student unionism and subsequent increase in campus facility fees on engagement in physical activity on campus. Participants: Participants were 1,904 students from a large regional NSW (Australia) university across 3 time periods (926 in 2005, 504 in 2006, and 474 in 2007). Methods: Students completed a survey across the 3 time periods, responding to questions about physical activity levels, use of on-campus and off-campus facilities, and barriers to facility use. Results: Participation in physical activity at university facilities was low overall, and declined substantially between 2005 and 2007, with …
Eliciting And Specifying Requirements For Highly Interactive Systems Using Activity Theory, Robert B. K. Brown, Peter Hyland, Ian C. Piper
Eliciting And Specifying Requirements For Highly Interactive Systems Using Activity Theory, Robert B. K. Brown, Peter Hyland, Ian C. Piper
Dr Ian Piper
The processes of eliciting user requirements and formalising these into specifications are critical for the success of highly interactive systems. These processes are still poorly understood, partly because current methods are usually ad hoc and lack any theoretical basis. A number of researchers have used Activity Theory (AT) to refine these processes and have met with some success. To date, this approach has been more useful explaining the processes post hoc. This positional paper proposes an AT method for requirement elicitation and specification definition. The method is sufficiently prescriptive and well formed that it does not require any detailed understanding …
Baseline Characteristics Of Volunteers In The Smart Clinical Trial: Associations Between Habitual Physical Activity And Lifestyle Disease Risk Factors, Qingsheng Zhang, Jane E. O'Shea, Rebecca L. Thorne, Linda C. Tapsell, Marijka Batterham, Karen E. Charlton
Baseline Characteristics Of Volunteers In The Smart Clinical Trial: Associations Between Habitual Physical Activity And Lifestyle Disease Risk Factors, Qingsheng Zhang, Jane E. O'Shea, Rebecca L. Thorne, Linda C. Tapsell, Marijka Batterham, Karen E. Charlton
Karen E. Charlton
Physical Activity has been suggested to have favorable effects on various cardiovascular risk factors, and may serve as an intervening variable in life-style intervention studies. We aimed to examine the relationship between habitual physical activity and selected cardiovascular markers at baseline in a sample of overweight women who participated in the SMART clinical trial [ACTRN12608000425392]. A sub-sample of eighty-six overweight/obese women (mean age ± S.D.: 45 ± 7.9 years) were included in this analysis. Anthropometric and fasting blood data was collected at baseline (t = 0). Habitual physical activity was assessed by a validated questionnaire (Baecke questionnaire). Associations were examined …
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
Bioregional Assessment Project: Sydney Metropolitan, Southern Rivers And Hawkesbury-Nepean Catchments: Data Collation Phase To Study The Impact Of Mining Activity And Coal Seam Gas On Environmental Assets, John Bradd, Tim Cohen, Sam Marx, Sol Buckman, Emma Burkhardt, A Clarke, Nicole Cook, Stephen Cullen, James Daley, Alexi Gavin, Ren Hu, Emma Kiekebosch-Fitt, Matt Lemcke, Andrew Lowe, Thomas Mcmahon, Luke Mcneilage, Kaitlyn O'Mara, Garth Nagle, Sam Robson, Carolyn Silveri, Joe Stammers
John M Bradd Dr
This study was commissioned by the Hawkesbury-Nepean (HNCMA), Sydney Metropolitan (SMCMA) and Southern Rivers (SRCMA) Catchment Management Authorities and undertaken by the University of Wollongong to collate existing data and to provide a preliminary assessment of the potential impacts of coal seam gas (CSG) and coal mining activities on environmental assets within the three CMA regions, where environmental assets were defined under three broad themes; water, land and biodiversity. This study formed part of the Australian Federal Government’s Department of Sustainability, Environment, Water, Population and Communities (SEWPaC) Bioregional Assessment initiative within regions potentially affected by CSG and coal mining activities. …
Activity As A Unit Of Analysis For Knowledge Management Frameworks, Leoni Warne, Irena Ali, Helen Hasan
Activity As A Unit Of Analysis For Knowledge Management Frameworks, Leoni Warne, Irena Ali, Helen Hasan
Helen Hasan
The authors of this paper take the view that knowledge management is a set of practices for systematically adding value to the knowlege of individuals, which is generated and shaped through interaction with others. It is therefore appropriate that knowledge management research be conducted in the context of particular organisations, focusing on local activities. To that end two of the authors have conducted a four-year research program investigating the factors in organizations that enhance and enable the assimilation, generation, sharing and building of knowledge that transfonns an organization into a learning organization. Human activities in organisational contexts have been analysed …
An Activity-Theory Analysis Of Corporate Wikis, Helen M. Hasan, Charmaine C. Pfaff
An Activity-Theory Analysis Of Corporate Wikis, Helen M. Hasan, Charmaine C. Pfaff
Helen Hasan
Purpose: Wiki technologies, which are popular in social settings, are beginning to contribute to more flexible and participatory approaches to the exploitation of knowledge in corporate settings. Through the lens of activity theory, this paper aims to investigate contentious challenges to organizational activities that may be associated with the introduction of corporate wikis, in particular the potential democratization of knowledge work. Design/methodology/approach: From a study of several cases of corporate wiki adoption, this paper presents and interprets two representative cases sampled to provide more generalized results. Qualitative data were collected through semi-structured interviews and observation. The analysis followed a systematic …
An Activity Theory Analysis Of A Case Of It-Driven Organisational Change, Wannapa Suratmethakul, Helen Hasan
An Activity Theory Analysis Of A Case Of It-Driven Organisational Change, Wannapa Suratmethakul, Helen Hasan
Helen Hasan
The paper describes unexpected problems encountered in the automation of a scheduling process using an IT application already in use in other similar organisations. A grounded theory approach was used to collect and categorise data on the case. Activity Theory was then used to analyse the attempt by management to implement organisational change through the introduction of the system. The findings suggest that it is inadvisable to impose organisational change through the introduction of a complex IT system, particularly when this disrupts entrenched decision-making processes of the organisation.
Decoupling Of Stretch Reflex And Background Muscle Activity During Anticipatory Postural Adjustments In Humans, Siddharth Vedula, Robert Kearney, Ross Wagner, Paul Stapley
Decoupling Of Stretch Reflex And Background Muscle Activity During Anticipatory Postural Adjustments In Humans, Siddharth Vedula, Robert Kearney, Ross Wagner, Paul Stapley
Dr Paul J Stapley
We studied the evolution of stretch reXexes in relation to background electromyographic (EMG) activity in the soleus muscle preceding the onset of voluntary arm raise movements. Our objective was to investigate if changes in reXex EMG and muscle activity occur simultaneously and are similarly scaled in amplitude. Ten human subjects stood with each foot on pedals able to exert short dorsiXexor pulses during stance. Subjects were asked to product consistent voluntary arm raise movements to a target upon a visual cue. In ¼ of trials, no pulse perturbations were given, but in the remaining ¾’s of all trials pulses were …
Synthesis Of Functionalised 2-Aryl-5-Nitro-1h-Indoles And Their Activity As Bacterial Nora Efflux Pump Inhibitors, John Bremner, Siritron Samosorn, Anthony Ball, Kim Lewis
Synthesis Of Functionalised 2-Aryl-5-Nitro-1h-Indoles And Their Activity As Bacterial Nora Efflux Pump Inhibitors, John Bremner, Siritron Samosorn, Anthony Ball, Kim Lewis
Kim Lewis
No abstract provided.
Structure-Activity Relationships Of 2-Aryl-1h-Indole Inhibitors Of The Nora Efflux Pump In Staphylococcus Aureus, John Bremner, Michael Kelso, Joseph Ambrus, Kim Lewis, Anthony Ball, Gabriele Casadei
Structure-Activity Relationships Of 2-Aryl-1h-Indole Inhibitors Of The Nora Efflux Pump In Staphylococcus Aureus, John Bremner, Michael Kelso, Joseph Ambrus, Kim Lewis, Anthony Ball, Gabriele Casadei
Kim Lewis
The synthesis of 22 2-aryl-1H-indoles, including 12 new compounds, has been achieved via Pd- or Rh-mediated methodologies, or selective electrophilic substitution. All three methods were based on elaborations from simple indole precursors. SAR studies on these indoles and 2-phenyl-1H-indole in Staphylococcus aureus as NorA efflux pump inhibitors indicated 5-nitro-2-(3-methoxycarbonyl)phenyl-1H-indole was a slightly more potent inhibitor than the lead INF55. A promising new antibacterial lead compound against S. aureus (2-phenyl-1H-indol-5-yl)-methanol, was also found.
Enhanced Molecular Chaperone Activity Of The Small Heat-Shock Protein Alphab-Cystallin Following Covalent Immobilization Onto A Solid-Phase Support, V Bellotti, Heath Ecroyd, J Carver, H J Griesser, B Thierry, J G Shapter, S S Griesser, S Giorgetti, M R Nussio, J A Gerrard, J Garvey
Enhanced Molecular Chaperone Activity Of The Small Heat-Shock Protein Alphab-Cystallin Following Covalent Immobilization Onto A Solid-Phase Support, V Bellotti, Heath Ecroyd, J Carver, H J Griesser, B Thierry, J G Shapter, S S Griesser, S Giorgetti, M R Nussio, J A Gerrard, J Garvey
Heath Ecroyd
The well-characterized small heat-shock protein, alphaB-crystallin, acts as a molecular chaperone by interacting with unfolding proteins to prevent their aggregation and precipitation. Structural perturbation (e.g., partial unfolding) enhances the in vitro chaperone activity of alphaB-crystallin. Proteins often undergo structural perturbations at the surface of a synthetic material, which may alter their biological activity. This study investigated the activity of alphaB-crystallin when covalently bound to a support surface; alphaB-crystallin was immobilized onto a range of solid material surfaces, and its characteristics and chaperone activity were assessed. Immobilization was achieved via a plasma-deposited thin polymeric interlayer containing aldehyde surface groups and reductive …
The Impact Of Complex Survey Design On Prevalence Estimates Of Intakes Of Food Groups In The Australian National Children's Nutrition And Physical Activity Survey, Sandy Burden, Yasmine Probst, David G. Steel, Linda C. Tapsell
The Impact Of Complex Survey Design On Prevalence Estimates Of Intakes Of Food Groups In The Australian National Children's Nutrition And Physical Activity Survey, Sandy Burden, Yasmine Probst, David G. Steel, Linda C. Tapsell
Professor David Steel
No abstract provided.
An Indoor Localisation And Motion Monitoring System To Determine Behavioural Activity In Dementia Afflicted Patients In Aged Care, Matthew D'Souza, Montserrat Ros, Mohanraj Karunanithi
An Indoor Localisation And Motion Monitoring System To Determine Behavioural Activity In Dementia Afflicted Patients In Aged Care, Matthew D'Souza, Montserrat Ros, Mohanraj Karunanithi
Dr Montserrat Ros
Dementia is highly prevalent among the older population. Most patients with dementia are admitted to an aged care facility due to wandering behaviour which tends to result in dangerous scenarios such as straying away from the facility and being seriously injured. Due to the decreasing availability of carers in aged care, there is a need to prioritise monitoring of patients that have a severe case of wondering. The challenge is to allow carers to monitor the status of such patients in terms of position localisation and motion behavioural status, in real-time. The long term behavioural analysis of such patients would …