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Social and Behavioral Sciences Commons™
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Articles 1 - 11 of 11
Full-Text Articles in Social and Behavioral Sciences
Discovering Motor Phenotypes In Autism Spectrum Disorder: A Cross-Syndrome Approach, Daniel Edwin Lidstone
Discovering Motor Phenotypes In Autism Spectrum Disorder: A Cross-Syndrome Approach, Daniel Edwin Lidstone
UNLV Theses, Dissertations, Professional Papers, and Capstones
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with a behavioral phenotype characterized by persistent deficits in social communication and social interaction accompanied by restricted, repetitive patterns of behaviors, interests, or activities. Currently in the US, approximately 2.5% of children have a diagnosis of ASD. The etiology of ASD is complex, however the disorder does have a strong genetic basis. Specific genetic mutations can lead to neuroanatomical and neurophysiological changes during development resulting in a behavioral phenotype that falls along the ASD spectrum and may result in a diagnosis of ASD. The severity of ASD-specific behaviors falls on a continuum …
Archaeological Analysis In The Information Age: Guidelines For Maximizing The Reach, Comprehensiveness, And Longevity Of Data, Sarah W. Kansa, Levent Atici, Eric C. Kansa, Richard H. Meadow
Archaeological Analysis In The Information Age: Guidelines For Maximizing The Reach, Comprehensiveness, And Longevity Of Data, Sarah W. Kansa, Levent Atici, Eric C. Kansa, Richard H. Meadow
Anthropology Faculty Research
With the advent of the Web, increased emphasis on “research data management,” and innovations in reproducible research practices, scholars have more incentives and opportunities to document and disseminate their primary data. This article seeks to guide archaeologists in data sharing by highlighting recurring challenges in reusing archived data gleaned from observations on workflows and reanalysis efforts involving datasets published over the past 15 years by Open Context. Based on our findings, we propose specific guidelines to improve data management, documentation, and publishing practices so that primary data can be more efficiently discovered, understood, aggregated, and synthesized by wider research communities.
Decline In Telomere Length By Age And Effect Modification By Gender, Allostatic Load And Comorbidities In National Health And Nutrition Examination Survey (1999-2002), Saruna Ghimire, Carl V. Hill, Francisco S. Sy, Rachelle Rodriguez
Decline In Telomere Length By Age And Effect Modification By Gender, Allostatic Load And Comorbidities In National Health And Nutrition Examination Survey (1999-2002), Saruna Ghimire, Carl V. Hill, Francisco S. Sy, Rachelle Rodriguez
Public Health Faculty Publications
Background: This study aims to assess the decline in telomere length (TL) with age and evaluate effect modification by gender, chronic stress, and comorbidity in a representative sample of the US population. Methods: Cross-sectional data on 7826 adults with a TL measurement, were included from the National Health and Nutrition Examination Survey, years 1999–2002. The population rate of decline in TL across 10-year age categories was estimated using crude and adjusted regression. Results: In an adjusted model, the population rate of decline in TL with age was consistent and linear for only three age categories: 20–29 (β = -0.0172, 95% …
Optimization Of Motor Performance, Lee-Kuen Chua
Optimization Of Motor Performance, Lee-Kuen Chua
UNLV Theses, Dissertations, Professional Papers, and Capstones
According to the OPTIMAL (Optimizing Performance Through Intrinsic Motivation and Attention of Learning) theory of motor learning, enhanced expectancies (EE), autonomy support (AS), and external focus (EF) augment the coupling of a person’s actions to intended movement goals. This goal-action coupling is postulated to boost a person’s focus on goal-related aspects of the motor task while reducing the person’s self-related thoughts, resulting in enhanced performance of skilled movements as well as in improving the acquisition outcomes for the learning of motor skills. The three studies in this compilation report were aimed at providing empirical evidence for the motor performance benefits …
Multi-Polygenic Risk Score Prediction Model For Bipolar Disorder, Travis Mize
Multi-Polygenic Risk Score Prediction Model For Bipolar Disorder, Travis Mize
UNLV Theses, Dissertations, Professional Papers, and Capstones
Bipolar disorder (BP), a severe mental disorder characterized by recurring manic and depressive episodes, has been shown to have a strong genetic underpinning. Current theory suggests that it is the summation of risk alleles, spread across the entirety of the genome, which contributes to the development of BP, as well as other polygenic traits. The comorbid nature of these polygenic traits are often problematic for diagnosticians as the symptomology of the disorders may vary substantially between individuals and can create diagnostic confusion. To alleviate issues such as these, a more objective measure, to be used alongside current diagnostic procedures, is …
Identification Of A Core Amino Acid Motif Within The Α Subunit Of Gabaars That Promotes Inhibitory Synaptogenesis And Resilience To Seizures, Anna J. Nathanson, Yihui Zhang, Joshua L. Smalley, Thomas A. Ollerhead, Miguel A. Rodriguez Santos, Peter M. Andrews, Heike J. Wobst, Yvonne E. Moore, Nicholas J. Brandon, Rochelle M. Hines, Paul A. Davies, Stephen J. Moss
Identification Of A Core Amino Acid Motif Within The Α Subunit Of Gabaars That Promotes Inhibitory Synaptogenesis And Resilience To Seizures, Anna J. Nathanson, Yihui Zhang, Joshua L. Smalley, Thomas A. Ollerhead, Miguel A. Rodriguez Santos, Peter M. Andrews, Heike J. Wobst, Yvonne E. Moore, Nicholas J. Brandon, Rochelle M. Hines, Paul A. Davies, Stephen J. Moss
Psychology Faculty Research
The fidelity of inhibitory neurotransmission is dependent on the accumulation of γ-aminobutyric acid type A receptors (GABAARs) at the appropriate synaptic sites. Synaptic GABAARs are constructed from α(1-3), β(1-3), and γ2 subunits, and neurons can target these subtypes to specific synapses. Here, we identify a 15-amino acid inhibitory synapse targeting motif (ISTM) within the α2 subunit that promotes the association between GABAARs and the inhibitory scaffold proteins collybistin and gephyrin. Using mice in which the ISTM has been introduced into the α1 subunit (Gabra1-2 mice), we show that the ISTM is critical for axo-axonic synapse formation, the efficacy of GABAergic …
Cardio-Metabolic Disease Risk Factors Among South Asian Labour Migrants To The Middle East: A Scoping Review And Policy Analysis, Shiva Raj Mishra, Saruna Ghimire, Chandni Joshi, Bishal Gyawali, Archana Shrestha, Dinesh Neupane, Sudesh Raj Sharma, Yashashwi Pokharel, Salim S. Virani
Cardio-Metabolic Disease Risk Factors Among South Asian Labour Migrants To The Middle East: A Scoping Review And Policy Analysis, Shiva Raj Mishra, Saruna Ghimire, Chandni Joshi, Bishal Gyawali, Archana Shrestha, Dinesh Neupane, Sudesh Raj Sharma, Yashashwi Pokharel, Salim S. Virani
Public Health Faculty Publications
This paper aims to explore the burgeoning burden of cardiovascular and metabolic disease (CMD) risk factors among South Asian labor migrants to the Middle East. We conducted a qualitative synthesis of literature using PubMed/Medline and grey literature searches, supplemented by a policy review of policies from the South Asian countries. We found a high burden of cardio-metabolic risk factors among the migrants as well as among the populations in the home and the host countries. For example, two studies reported the prevalence of diabetes mellitus (DM) ranging between 9 and 17% among South Asian migrants. Overweight and obesity were highly …
College Student Depression: An Examination Of Cardiorespiratory Fitness, Gender And Sexual Orientation Diversity, And Help-Seeking Willingness, Sharon Jalene
UNLV Theses, Dissertations, Professional Papers, and Capstones
Depression is a serious illness characterized by persistent low mood, reduced cognitive capacity, and fatigue. Although treatable, depression is the leading cause of disability and ill-health worldwide and a significant contributor to suicide, the second leading cause of death for young Americans. In any given two-week period, 8.1% of adults in the United States had moderate to severe depression (2013-2016). The rate of depression for females was twice that of males and compared to the majority, sexual and gender minorities (SGM) were at a threefold risk. Furthermore, evidence suggests that depression incidence is three times higher in college students than …
From Deviant Symbol To Cultural Icon? Understanding Pit Bull Stigma, Genevieve Minter
From Deviant Symbol To Cultural Icon? Understanding Pit Bull Stigma, Genevieve Minter
UNLV Theses, Dissertations, Professional Papers, and Capstones
This research draws from twelve months of ethnographic data using Las Vegas as a case study to understand how pit bull owners experience and negotiate stigma in various social settings. The human-dog relationship, long rooted in utility, transformed in the modern era as animals were promoted from worker to companion. The world’s first dog register, The American Kennel Club, created breed standards and encouraged selective breeding, which influenced the idea of certain dogs being more physically “dangerous” than others. Though the pit bull is not the first dog “breed” to be the object of discrimination, it is the first dog …
Analysis Of Spheno-Occipital Synchondrosis (Sos) Fusion In A Contemporary Southern Nevada Subadult Hispanic Population Using Archival Cone-Beam Computerized Tomography (Cbct) Images, Megan Baker
UNLV Theses, Dissertations, Professional Papers, and Capstones
This study employs the three-dimensional visualization capability of cone-beam computed tomography (CBCT) to investigate the relationship between chronological age and timing of fusion of the spheno-occipital synchondrosis in a male/female subadult Hispanic population of Southern Nevada. The sample includes cross-sectional data of 374 orthodontic patients (166 males and 208 females) aged 8-20 years. The SOS is scored by a four-stage scoring system as completely open (stage 0), less than half fused (stage 1), more than half fused (stage 2), or completely fused (stage 3) as visualized in the midsagittal plane in the CBCT image. The relationship between SOS fusion stage …
Nutrient And Food Group Intakes Of Low-Income Pregnant Women By Race/Ethnicity, Alla M. Hill, Danielle L. Nunnery Phd, Rdn, Ldn, Alice Ammerman Drph, Jigna M. Dharod Phd
Nutrient And Food Group Intakes Of Low-Income Pregnant Women By Race/Ethnicity, Alla M. Hill, Danielle L. Nunnery Phd, Rdn, Ldn, Alice Ammerman Drph, Jigna M. Dharod Phd
Journal of Health Disparities Research and Practice
In an exploratory study, a convenience sample of 148 pregnant women was recruited from a WIC clinic in the southeast region of the U.S. to: 1) Examine and compare daily nutrient and food group intakes of WIC pregnant women to national guidelines, and; 2) Determine racial/ethnic differences in nutrient and food group intakes among WIC pregnant women. Women were selected for the study if they were: ≥ 18 y, in 2nd trimester of pregnancy, and if they spoke English or Spanish as a first language. Upon recruitment, participants were interviewed to collect information on their socio-demographics, including race/ethnicity. Additionally, …