Social and Behavioral Sciences Commons^™

Neurocognitive Correlates Of Treatment Response In Children With Tourette's Disorder, Susanna W. Chang, Joseph F. Mcguire, John T. Walkup, Douglas W. Woods, Lawrence Scahill, Sabine Wilhelm, Alan L. Peterson, James Dziura, John Piacentini

Psychology Faculty Research and Publications

This paper examined neurocognitive functioning and its relationship to behavior treatment response among youth with Tourette's Disorder (TD) in a large randomized controlled trial. Participants diagnosed with TD completed a brief neurocognitive battery assessing inhibitory functions, working memory, and habit learning pre- and post-treatment with behavior therapy (CBIT, Comprehensive Behavioral Intervention for Tics) or psychoeducation plus supportive therapy (PST). At baseline, youth with tics and Attention Deficit Hyperactivity Disorder (ADHD) exhibited some evidence of impaired working memory and simple motor inhibition relative to youth with tics without ADHD. Additionally, a small negative association was found between antipsychotic medications and youth's …