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Full-Text Articles in Social and Behavioral Sciences

Tyrosine Phosphorylation Of Hsp-90 During Mammalian Sperm Capacitation, Heath Ecroyd, Russell Jones, Robert Aitken Dec 2011

Tyrosine Phosphorylation Of Hsp-90 During Mammalian Sperm Capacitation, Heath Ecroyd, Russell Jones, Robert Aitken

Heath Ecroyd

The process of sperm capacitation is correlated with activation of a signal transduction pathway leading to protein tyrosine phosphorylation. Whereas phosphotyrosine expression is an essential prerequisite for fertilization, the proteins that are phosphorylated during capacitation have not yet been identified. In the present study, we observed that a major target of this signaling pathway is the molecular chaperone protein, heat shock protein (HSP)-86, a member of the HSP-90 family of HSPs. We used cross-immunoprecipitation experiments to confirm the tyrosine phosphorylation of HSP-86, a process that is not inhibited by the ansamycin antibiotic, geldanamycin. The general significance of these findings was …


The Development Of Signal Transduction Pathways During Epididymal Maturation Is Calcium Dependent, Heath W. Ecroyd, Kelly Asquith, Russell C. Jones, Robert J. Aitken Dec 2011

The Development Of Signal Transduction Pathways During Epididymal Maturation Is Calcium Dependent, Heath W. Ecroyd, Kelly Asquith, Russell C. Jones, Robert J. Aitken

Heath Ecroyd

Capacitation has been correlated with the activation of a cAMP-PKA-dependent signaling pathway leading to protein tyrosine phosphorylation. The ability to exhibit this response to cAMP matures during epididymal maturation in concert with the ability of the sperrnatozoa to capacitate. In this study, we have addressed the mechanisms by which spermatozoa gain the potential to activate this signaling pathway during epididymal maturation. In a modified Tyrode's medium containing 1.7 mM calcium, caput spermatozoa had significantly higher [Ca2+](i) than caudal cells and could not tyrosine phosphorylate in response to cAMP. However, in calcium-depleted medium both caput and caudal cells could exhibit a …


Activity Counts From Accelerometers Do Not Add Value To Energy Expenditure Predictions In Sedentary Overweight Individuals During Weight Loss Interventions, Sze Yen Tan, Marijka Batterham, Linda C. Tapsell Jan 2011

Activity Counts From Accelerometers Do Not Add Value To Energy Expenditure Predictions In Sedentary Overweight Individuals During Weight Loss Interventions, Sze Yen Tan, Marijka Batterham, Linda C. Tapsell

Faculty of Health and Behavioural Sciences - Papers (Archive)

Background: Knowing the total energy expenditure (TEE) of overweight adults is important for prescribing weight loss interventions. However, objective measurements of TEE may not always be readily available and can be expensive. This study aimed to investigate the validity of RT3 accelerometers in predicting the TEE of sedentary overweight adults, and to identify any sensitivity to anthropometric changes. Methods: The analysis used data from a 12-week weight loss study. At baseline and 12-week, TEE was predicted using RT3 accelerometers during whole room calorimeter stays. Bias between 2 methods was compared at and between the baseline and 12-week measurement points. Multiple …


An Investigation Of Forearm Vasomotor And Sudomotor Thresholds During Passive Heating, Following Whole-Body Cooling, Joanne N. Caldwell, Asa Nykvist, Nicholas Powers, Sean R. Notley, Daniel S. Lee, Gregory E. Peoples, Nigel A.S Taylor Jan 2011

An Investigation Of Forearm Vasomotor And Sudomotor Thresholds During Passive Heating, Following Whole-Body Cooling, Joanne N. Caldwell, Asa Nykvist, Nicholas Powers, Sean R. Notley, Daniel S. Lee, Gregory E. Peoples, Nigel A.S Taylor

Faculty of Health and Behavioural Sciences - Papers (Archive)

No abstract provided.


Sensitization Behaviour Of 11-12% Cr Aisi 409 Stainless Steel During Low Heat Input Welding, Cornelis Janise Van Niekerk, Madeleine Du Toit Jan 2011

Sensitization Behaviour Of 11-12% Cr Aisi 409 Stainless Steel During Low Heat Input Welding, Cornelis Janise Van Niekerk, Madeleine Du Toit

Faculty of Engineering and Information Sciences - Papers: Part A

The study comprised of the investigation into the sensitization characteristics of AISI 409 titanium stabilized ferritic stainless steel during low heat input welding. AISI 409 is a fully ferritic stainless steel used in catalytic converters and tubing for automotive exhaust systems due to the supposition that sensitization does not occur during low heat input welding. Two plates of 2 and 4 mm were tested for sensitization during low heat input welding. The study confirmed that chromium carbide (M23C6) precipitation occurs on the grain boundaries in the heat-affected zone with consequent depletion of Cr adjacent to the …


Bauschinger Effect In Microalloyed Steels: Part Ii. Influence Of Work Softening On Strength Development During Uoe Line-Pipe Forming, Andrii Kostryzhev, Martin Strangwood, Claire L. Davis Jan 2011

Bauschinger Effect In Microalloyed Steels: Part Ii. Influence Of Work Softening On Strength Development During Uoe Line-Pipe Forming, Andrii Kostryzhev, Martin Strangwood, Claire L. Davis

Faculty of Engineering and Information Sciences - Papers: Part A

The Bauschinger effect (a reduced yield stress at the start of reverse deformation following forward prestrain) is an important factor of strength development for cold metal forming technology. In steels, the magnitude of the Bauschinger effect depends on composition, through the presence of microalloy precipitates, and prior processing, through the size and distribution of the microalloy precipitates and the presence of retained work hardening. In this article, the parameters of the Bauschinger effect and work hardening (coefficient and exponent) in forward and reverse deformations were quantitatively related to the particle number density and dislocation density for two high-strength low-alloy (HSLA) …


The Type And Prevalence Of Activities Performed By Australian Children During The Lunchtime And After School Periods, Rebecca M. Stanley, Kate Ridley, Timothy Olds Jan 2011

The Type And Prevalence Of Activities Performed By Australian Children During The Lunchtime And After School Periods, Rebecca M. Stanley, Kate Ridley, Timothy Olds

Faculty of Social Sciences - Papers (Archive)

Objectives: The aim of this study was to identify the most prevalent reported activities performed by Australian children during the lunchtime and after school periods; and estimate the mean duration of a typical bout of the most prevalent activities performed during the lunchtime and after school periods. Design: This study was a secondary data analysis of the 2007 Australian National Children's Nutrition and Physical Activity Survey. Method: Use of time data were collected from Australian children aged 10.0-13.9 years (n = 794) using the Multimedia Activity Recall for Children and Adults (MARCA). The most prevalent self-reported activities for the lunchtime …


Study On Oxidation Of Stainless Steels During Hot Rolling, Z Y. Jiang, D B. Wei, K Tieu, J X. Huang, A W. Zhang, X Shi, S H. Jiao Jan 2011

Study On Oxidation Of Stainless Steels During Hot Rolling, Z Y. Jiang, D B. Wei, K Tieu, J X. Huang, A W. Zhang, X Shi, S H. Jiao

Faculty of Engineering and Information Sciences - Papers: Part A

The oxidation of stainless steels 304 and 304L during hot rolling is studied in this paper. Results show the oxide scale thickness decreases significantly with an increase of reduction, and the oxide scales of both 304 and 304L stainless steels were found more deformable than the steel substrate. Surface roughness shows a complicated transfer during the hot rolling process due to the complexity of oxide scale characteristics. Also, surface roughness decreases with an increase of reduction. The friction coefficient increases with reduction in all cases, and the increase is more significant in the case of the 304 stainless steel than …


Does Managerial Signalling Behaviour Affect Conflict During Npd Projects: An Exploratory Study, Elias Kyriazis, Les Johnson, Paul Couchman Jan 2011

Does Managerial Signalling Behaviour Affect Conflict During Npd Projects: An Exploratory Study, Elias Kyriazis, Les Johnson, Paul Couchman

Faculty of Commerce - Papers (Archive)

Cross-functional relationships during NPD projects have received considerable researchattention with an emphasis on achieving successful integration and avoiding harmfulconflict. The purpose of this paper is to develop and test an exploratory model examiningthe effects of managerial signalling behaviour, at top management and functional level,on conflict in cross-functional working relationships. Focussing on working relationshipbetween marketing managers and R&D managers in 184 new product developmentprojects in Australia this study examines the antecedents of conflict as reported by theR&D Manager. This study provides empirical support for the proposition that while topmanagement actions are useful in facilitating integration, the way a manager perceivestheir functional …