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Full-Text Articles in Social and Behavioral Sciences

Analysis Of The Mechanism By Which Calcium Negatively Regulates The Tyrosine Phosphorylation Cascade Associated With Sperm Capacitation, Mark Baker, Louise Hethrington, Heath Ecroyd, Shaun Roman, Robert Aitken Dec 2011

Analysis Of The Mechanism By Which Calcium Negatively Regulates The Tyrosine Phosphorylation Cascade Associated With Sperm Capacitation, Mark Baker, Louise Hethrington, Heath Ecroyd, Shaun Roman, Robert Aitken

Heath Ecroyd

The capacitation of mammalian spermatozoa involves the activation of a cAMP-mediated signal transduction pathway that drives tyrosine phosphorylation via mechanisms that are unique to this cell type. Controversy surrounds the impact of extracellular calcium on this process, with positive and negative effects being recorded in independent publications. We clearly demonstrate that the presence of calcium in the external medium decreases tyrosine phosphorylation in both human and mouse spermatozoa. Under these conditions, a rise in intracellular pH was recorded, however, this event was not responsible for the observed changes in phosphotyrosine expression. Rather, the impact of calcium on tyrosine phosphorylation in …


An Analysis On Non-Finite Verb Forms As An Indication Of The Style Of Translation In Bede's Ecclesiastical History, Richard Clement Nov 2011

An Analysis On Non-Finite Verb Forms As An Indication Of The Style Of Translation In Bede's Ecclesiastical History, Richard Clement

Richard W. Clement

Non-finite verb forms are ideal as indicators of a translator's ability and style of translating Latin into OE. (1) This is because in Latin there are six different infinitives: the present active infinitive, the present passive infinitive, the perfect active infinitive, the perfect passive infinitive, the future active infinitive, and the future passive infinitive. However, in OE there is only one infinitive: the present active infinitive. In Latin there are four different participles: the present active imperfect participle, the present passive perfective participle, the future active imperfective participle, and the future passive imperfective participle (gerundive). The gerund is the neuter …