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Full-Text Articles in Social and Behavioral Sciences

Syntheses Of Spiro[Cyclopropane-1,3'-Oxindole]-2-Carboxylic Acid And Cyclopropa[C]Quinoline-7b-Carboxylic Acid And Their Derivatives, Sarah Yong, Alison T. Ung, Stephen G. Pyne, Brian W. Skelton, Allan H. White Jan 2007

Syntheses Of Spiro[Cyclopropane-1,3'-Oxindole]-2-Carboxylic Acid And Cyclopropa[C]Quinoline-7b-Carboxylic Acid And Their Derivatives, Sarah Yong, Alison T. Ung, Stephen G. Pyne, Brian W. Skelton, Allan H. White

Faculty of Science - Papers (Archive)

The synthesis of spiro[cyclopropane-1,3′-oxindole]-2-carboxylic acid, including novel 3-(2- and 3-pyridyl)-substituted analogues and the novel cyclopropa[c]quinoline-7b-carboxylic acid and their ester and amide derivatives is described. These syntheses involve diastereoselective cyclopropanation reactions of methyl 2-(2-nitrophenyl)acrylate and (3E)-(pyridin-2-ylmethylene)- and (3E)-(pyridin-3-ylmethylene)-1,3-dihydro-2H-indol-2-one with ethyl (dimethyl sulfuranylidene) acetate (EDSA). The synthesis of methyl cyclopropa[c]quinoline-7b-carboxylate involves a regioselective reductive cyclization of a nitro-diester precursor. The relative stereochemistry of key compounds has been determined by single-crystal X-ray structural analysis.


Nutrigenomics Applied To An Animal Model Of Inflammatory Bowel Diseases: Transcriptomic Analysis Of The Effects Of Eicosapentaenoic Acid-And Arachidonic Acid-Enriched Diets, Nicole Roy, Matthew Barnett, Bianca Knoch, Yvonne Dommels, Warren Mcnabb Jan 2007

Nutrigenomics Applied To An Animal Model Of Inflammatory Bowel Diseases: Transcriptomic Analysis Of The Effects Of Eicosapentaenoic Acid-And Arachidonic Acid-Enriched Diets, Nicole Roy, Matthew Barnett, Bianca Knoch, Yvonne Dommels, Warren Mcnabb

Faculty of Science - Papers (Archive)

In vivo models of Inflammatory Bowel Diseases (IBD) elucidate important mechanisms of chronic inflammation. Complex intestinal responses to food components create a unique “fingerprint” discriminating health from disease. Five-week-old IL10−/− and C57BL/6J (C57; control) mice were inoculated orally with complex intestinal microflora (CIF) and/or pure cultures of Enterococcus faecalis and E. faecalis (EF) aiming for more consistent inflammation of the intestinal mucosa. Inoculation treatments were compared to non-inoculated IL10−/− and C57 mice, either kept in specific pathogen free (SPF) or conventional conditions (2×5 factorial design). At 12 weeks of age, mice were sacrificed for intestinal histological (HIS) and transcriptomic analysis …


Conjugated Linoleic Acid Versus High-Oleic Acid Sunflower Oil: Effects On Energy Metabolism, Glucose Tolerance, Blood Lipids, Appetite And Body Composition In Regularly Exercising Individuals, Estelle V. Lambert, Julia H. Goedecke, Kerrie Bluett, Kerry Heggie, Amanda Claassen, Dale E. Rae, Sacha West, Jonathan Dugas, Lara Dugas, Shelly Meltzer, Karen E. Charlton, Inge Mohede Jan 2007

Conjugated Linoleic Acid Versus High-Oleic Acid Sunflower Oil: Effects On Energy Metabolism, Glucose Tolerance, Blood Lipids, Appetite And Body Composition In Regularly Exercising Individuals, Estelle V. Lambert, Julia H. Goedecke, Kerrie Bluett, Kerry Heggie, Amanda Claassen, Dale E. Rae, Sacha West, Jonathan Dugas, Lara Dugas, Shelly Meltzer, Karen E. Charlton, Inge Mohede

Faculty of Science, Medicine and Health - Papers: part A

The aim of this study was to measure the effects of 12 weeks of conjugated linoleic acid (CLA) supplementation on body composition, RER, RMR, blood lipid profiles, insulin sensitivity and appetite in exercising, normal-weight persons. In this double-blind, randomised, controlled trial, sixty-two non-obese subjects (twenty-five men, thirty-seven women) received either 3.9 g/d CLA or 3.9 g high-oleic acid sunflower oil for 12 weeks. Prior to and after 12 weeks of supplementation, oral glucose tolerance, blood lipid concentrations, body composition (dual-energy X-ray absorptiometry and computerised tomography scans), RMR, resting and exercising RER and appetite were measured. There were no significant effects …


Fatty Acid Intakes And Food Sources In A Population Of Older Australians, Victoria M. Flood, Karen L. Webb, Elena Rochtchina, Bridget P. Kelly, Paul Mitchell Jan 2007

Fatty Acid Intakes And Food Sources In A Population Of Older Australians, Victoria M. Flood, Karen L. Webb, Elena Rochtchina, Bridget P. Kelly, Paul Mitchell

Faculty of Health and Behavioural Sciences - Papers (Archive)

This population-based descriptive study documents fatty acid intakes in a population of older Australians. It will serve as a basis for investigations of associations between dietary fatty acid intakes and a number of eye diseases.


Fortification Of Foods With Folic Acid And Iodine, Victoria M. Flood Jan 2007

Fortification Of Foods With Folic Acid And Iodine, Victoria M. Flood

Faculty of Health and Behavioural Sciences - Papers (Archive)

Last year, Food standards Australia New Zealand (FSANZ) made two key proposals for the mandatory fortification of foods in Australia with folic acid and iodine.1,2 In the case of folic acid, the goal is to increase the folic acid intake of women of child bearing age in order to reduce the incidence of neural tube defects (NTDs) such as spina bifi da and related birth defects. Fortifi cation of foods with iodine aims to increase the intake of this nutrient by women of child bearing age, and of children to reduce the prevalence of iodine deficiency (including goitre and impaired …