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Full-Text Articles in Social and Behavioral Sciences

Initial Studies On Alkaloids From Lombok Medicinal Plants, Surya Hadi, John B. Bremner Jan 2001

Initial Studies On Alkaloids From Lombok Medicinal Plants, Surya Hadi, John B. Bremner

Faculty of Science, Medicine and Health - Papers: part A

Initial investigation of medicinal plants from Lombok has resulted in the collection of 100 plant species predicted to have antimicrobial, including antimalarial, properties according to local medicinal uses. These plants represent 49 families and 80 genera; 23% of the plants tested positively for alkaloids. Among the plants testing positive, five have been selected for further investigation involving structure elucidation and antimicrobial testing on the extracted alkaloids. Initial work on structural elucidation of some of the alkaloids is reported briefly.


Indole Derivatives From The Egg Masses Of Muricid Molluscs, Kirsten Benkendorff, John B. Bremner, Andrew R. Davis Jan 2001

Indole Derivatives From The Egg Masses Of Muricid Molluscs, Kirsten Benkendorff, John B. Bremner, Andrew R. Davis

Faculty of Science, Medicine and Health - Papers: part A

A range of brominated indole derivatives were found in the egg masses of six species of muricid molluscs. Several non-brominated indoles were also present in the eggs of two Mediterranean Muricidae, although these were not found in the Australian species. Tyrindoleninone (3), was the only compound found in all six species and is likely to be responsible for the observed antimicrobial activity of these muricid egg masses [1,2]. These bioactive indoles appear to be characteristic of muricid egg masses and were not found in the egg masses from 17 species in different families of marine molluscs.


Detection Of P2x Purinergic Receptors On Human B Lymphocytes, Ronald Sluyter, J A. Barden, James Wiley Jan 2001

Detection Of P2x Purinergic Receptors On Human B Lymphocytes, Ronald Sluyter, J A. Barden, James Wiley

Faculty of Science - Papers (Archive)

B lymphocytes are known to synthesise the P2X(7) subtype of the P2X purinergic receptor family; however, the identification of the other six P2X subtypes on these cells has been limited by the absence of specific antibodies. In this study, we used a panel of anti-P2X polyclonal antibodies and confocal microscopy to examine the presence of each P2X receptor on human B lymphocytes. We observed that P2X(1), P2X(2), P2X(4) and P2X(7) subtypes, but not P2X(3), P2X(5) and P2X(6) subtypes, are present on B lymphocytes.