Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Social and Behavioral Sciences
Effect Of Ondansetron And Delta(9)-Tetrahydrocannabinol On The Establishment Of Lithium-Induced Conditioned Taste Avoidance In The House Musk Shrew (Suncus Murinus), Magdalena Kwiatkowska
Effect Of Ondansetron And Delta(9)-Tetrahydrocannabinol On The Establishment Of Lithium-Induced Conditioned Taste Avoidance In The House Musk Shrew (Suncus Murinus), Magdalena Kwiatkowska
Theses and Dissertations (Comprehensive)
Recent evidence suggests that toxin-induced taste avoidance in the non-emetic rat is not mediated by conditioned sickness. In contrast, it appears that toxin-induced taste avoidance in an emetic species is mediated by conditioned sickness. The present experiments evaluated the potential of the anti-emetic agents, ondansetron [OND; a serotonin receptor (5-HT3) antagonist] and Delta(9)-tetrahydrocannabinol [THC; a cannabinoid (CB 1) agonist] to interfere with lithium chloride (LiCl)-induced taste avoidance in the house musk shrew (Suncus murinus). In Experiment 1, shrews were pretreated with OND (1.5 mg/kg) or saline 30 min prior to drinking 0.1% saccharin solution then they were injected with LiCl …