Social and Behavioral Sciences Commons^™

Enrichment And Training Improve Cognition In Rats With Cortical Malformations, Kyle R. Jenks, Marcella M. Lucas, Ben A. Duffy, Ashlee A. Robbins, Barjor Gimi, Jeremy M. Barry, Rod C. Scott

Dartmouth Scholarship

Children with malformations of cortical development (MCD) frequently have associated cognitive impairments which reduce quality of life. We hypothesized that cognitive deficits associated with MCD can be improved with environmental manipulation or additional training. The E17 methylazoxymethanol acetate (MAM) exposure model bears many anatomical hallmarks seen in human MCDs as well as similar behavioral and cognitive deficits. We divided control and MAM exposed Sprague-Dawley rats into enriched and non-enriched groups and tested performance in the Morris water maze. Another group similarly divided underwent sociability testing and also underwent Magnetic Resonance Imaging (MRI) scans pre and post enrichment. A third group …

Is Pressure Stressful? The Impact Of Pressure On The Stress Response And Category Learning, Shannon L. Mccoy, Steven B. Hutchinson, Lauren Hawthorne, Brandon J. Cosley, Shawn W. Ell

Psychology Faculty Scholarship

We examine the basic question of whether pressure is stressful. We propose that when examining the role of stress or pressure in cognitive performance it is important to consider the type of pressure, the stress response, and the aspect of cognition assessed. In Experiment 1, outcome pressure was not experienced as stressful but did lead to impaired performance on a rule-based (RB) category learning task and not a more procedural information-integration (II) task. In Experiment 2, the addition of monitoring pressure resulted in a modest stress response to combined pressure and impairment on both tasks. Across experiments, higher stress appraisals …

Self-Regulatory Depletion Increases Emotional Reactivity In The Amygdala, Dylan D. Wagner, Todd F. Heatherton

Dartmouth Scholarship

The ability to self-regulate can become impaired when people are required to engage in successive acts of effortful self-control, even when self-control occurs in different domains. Here, we used functional neuroimaging to test whether engaging in effortful inhibition in the cognitive domain would lead to putative dysfunction in the emotional domain. Forty-eight participants viewed images of emotional scenes during functional magnetic resonance imaging in two sessions that were separated by a challenging attention control task that required effortful inhibition (depletion group) or not (control group). Compared to the control group, depleted participants showed increased activity in the left amygdala to …

Decoding The Neural Mechanisms Of Human Tool Use., Jason P Gallivan, D Adam Mclean, Kenneth F Valyear, Jody C Culham

Brain and Mind Institute Researchers' Publications

Sophisticated tool use is a defining characteristic of the primate species but how is it supported by the brain, particularly the human brain? Here we show, using functional MRI and pattern classification methods, that tool use is subserved by multiple distributed action-centred neural representations that are both shared with and distinct from those of the hand. In areas of frontoparietal cortex we found a common representation for planned hand- and tool-related actions. In contrast, in parietal and occipitotemporal regions implicated in hand actions and body perception we found that coding remained selectively linked to upcoming actions of the hand whereas …

Comprehensive Behavioral Characterization Of An App/Ps-1 Double Knock-In Mouse Model Of Alzheimer's Disease, Scott J. Webster, Adam D. Bachstetter, Linda J. Van Eldik

Sanders-Brown Center on Aging Faculty Publications

INTRODUCTION: Despite the extensive mechanistic and pathological characterization of the amyloid precursor protein (APP)/presenilin-1 (PS-1) knock-in mouse model of Alzheimer's disease (AD), very little is known about the AD-relevant behavioral deficits in this model. Characterization of the baseline behavioral performance in a variety of functional tasks and identification of the temporal onset of behavioral impairments are important to provide a foundation for future preclinical testing of AD therapeutics. Here we perform a comprehensive behavioral characterization of this model, discuss how the observed behavior correlates with the mechanistic and pathological observations of others, and compare this model with other commonly used …

Anterior And Posterior Types Of Neuropsychological Deficits In Parkinson’S Disease: A Subgroup Classification Of Cognitive Outcome, Megan M. Risi

Honors Program Theses and Projects

Individuals with Parkinson’s disease (PD) exhibit cognitive deficits. Recent studies suggest there are distinct cognitive profiles of PD characterized by deficits in abilities that are dependent upon anterior versus posterior areas of the brain. While anterior-based deficits are more prevalent, posterior-based deficits are more predictive of the future occurrence of dementia in PD. The purpose of the current project was to examine these cognitive profiles in more detail. Performance on six tests of anterior function and six tests of posterior function was examined in 34 non-demented PD participants and 27 healthy control participants matched for age and education. Results showed …

The Influence Of Spatial Distance Priming On Test Anxiety And Judgments, Eric R Raap

Masters Theses & Specialist Projects

This paper examined the effects of distance priming on test anxiety and judgment. Research suggests that individuals’ perceived distance can impact their affect and judgments, which sheds light on the principle of “distance equals safety” (Williams & Bargh, 2008). Taking an exam invokes both cognitive and emotional anxiety, such as worry, panic, and tension. It is hypothesized that the distance priming may reduce test anxiety—particularly, the emotionality aspect—as well as perceived test difficulty. The results showed that, counter to the hypotheses, there was no significant difference among the three priming groups in their emotional test anxiety or perceived test difficulty. …

Ages Of Engagement In Risk Taking And Self-Harm: An Investigation Of The Dual Systems Model Of Adolescent Risk Taking, Brittany Dykstra

Masters Theses & Specialist Projects

Risk taking (RT) and self-harm (SH) are clinically, conceptually, and empirically
related, yet separate constructs, which occur most frequently during adolescence. The current study utilized retrospective reports of college students to determine reported ages of engagement in RT and SH behaviors. Reported ages were compared with predictions for ages of high frequency engagement in RT based on the Dual Systems Model of Adolescent Risk Taking (DSMART; Steinberg, 2010). The sample consisted of 228 college students, ranging in age from 18 to 48 years (mean 22.8), who completed a survey of commonly investigated RT (12 items) and SH (18 items) behaviors. …

The Influence Of Children's Affective Ties On The Goal Clarification Step Of Social Information Processing, Amanda C. Thorn

Masters Theses & Specialist Projects

Previous studies have shown that children’s social goals are influenced by
emotion and that emotions can be manipulated using relationships. The present study combines these previous findings by examining the effect of children’s relationships on social goals. Social goals were examined in second and fifth grade children using hypothetical ambiguous provocation situations in which the relationship between the participant and the provocateur was manipulated by inserting the name of a friend, enemy, or a neutral peer into the story. After each situation, children rated the importance of four different social goals, indicating which of the four would be the most …

Intrinsic And Extrinsic Motivation: Abraham Lincoln As An Adult Learner, Warren Greer

Masters Theses & Specialist Projects

Over the last two decades, research has identified factors that foster versus undermine human motivation and well being with important implications for learning and performance. Much of the research is concerned with intrinsic versus extrinsic motivation and autonomous versus non-autonomous learning environments. The data suggests that learning and performance are often significantly enhanced in autonomy-supportive environments that foster intrinsic motivational perspectives. This study examines the lived experience of Abraham Lincoln in the context of his adult learning motivation, forming a qualitative narrative around his adult educational experiences. It was hypothesized that Abraham Lincoln benefited from learning experiences with high levels …

Fkbp5 Modulates Attention Bias For Threat: Associations With Hippocampal Function And Morphology, Negar Fani, David Gutman, Erin Tone, Lynn Almli, Kristina B. Mercer, Jennifer Davis, Ebony Glover, Tanja Jovanovic, Bekh Bradley, Ivo D. Dinov, Alen Zamanyan, Arthur W. Toga, Elisabeth B. Binder, Kerry J. Ressler

Psychology Faculty Publications

Context: The FKBP5 gene product regulates glucocorticoid receptor (GR) sensitivity and hypothalamicpituitary‐adrenal axis functioning, and has been associated with a number of stress‐related psychiatric disorders. The study of intermediate phenotypes, such as emotion‐processing biases and their neural substrates, provides a way to clarify the mechanisms by which FKBP5 dysregulation mediates psychopathology risk.

Objective: To examine whether allelic variations for a putatively functional SNP associated with FKBP5 gene regulation (rs1360780) would relate differentially to attentional bias for threat; this was measured through behavioral response on a dot probe task and hippocampal activation during task performance. Morphological substrates of differential hippocampal response …

Physical Activity And Brain Function In Older Adults At Increased Risk For Alzheimer’S Disease, J. Carson Smith, Kristy A. Nielson, John L. Woodard, Michael Seidenberg, Stephen M. Rao

Psychology Faculty Research and Publications

Leisure-time physical activity (PA) and exercise training are known to help maintain cognitive function in healthy older adults. However, relatively little is known about the effects of PA on cognitive function or brain function in those at increased risk for Alzheimer’s disease through the presence of the apolipoproteinE epsilon4 (APOE-ε4) allele, diagnosis of mild cognitive impairment (MCI), or the presence of metabolic disease. Here, we examine the question of whether PA and exercise interventions may differentially impact cognitive trajectory, clinical outcomes, and brain structure and function among individuals at the greatest risk for AD. The literature suggests that the protective …

Implicitly Priming The Social Brain: Failure To Find Neural Effects, Katherine E. Powers, Todd F. Heatherton

Dartmouth Scholarship

Humans have a fundamental need for social relationships. Rejection from social groups is especially detrimental, rendering the ability to detect threats to social relationships and respond in adaptive ways critical. Indeed, previous research has shown that experiencing social rejection alters the processing of subsequent social cues in a variety of socially affiliative and avoidant ways. Because social perception and cognition occurs spontaneously and automatically, detecting threats to social relationships may occur without conscious awareness or control. Here, we investigated the automaticity of social threat detection by examining how implicit primes affect neural responses to social stimuli. However, despite using a …

Music And Movement Share A Dynamic Structure That Supports Universal Expressions Of Emotion, Beau Sievers, Larry Polansky, Michael Casey, Thalia Wheatley

Dartmouth Scholarship

Music moves us. Its kinetic power is the foundation of human behaviors as diverse as dance, romance, lullabies, and the military march. Despite its significance, the music-movement relationship is poorly understood. We present an empirical method for testing whether music and movement share a common structure that affords equivalent and universal emotional expressions. Our method uses a computer program that can generate matching examples of music and movement from a single set of features: rate, jitter (regularity of rate), direction, step size, and dissonance/visual spikiness. We applied our method in two experiments, one in the United States and another in …

Science, Sentience, And Animal Welfare, Robert C. Jones

Ethics and Animal Welfare Collection

I sketch briefly some of the more influential theories concerned with the moral status of nonhuman animals, highlighting their biological/physiological aspects. I then survey the most prominent empirical research on the physiological and cognitive capacities of nonhuman animals, focusing primarily on sentience, but looking also at a few other morally relevant capacities such as self-awareness, memory, and mindreading. Lastly, I discuss two examples of current animal welfare policy, namely, animals used in industrialized food production and in scientific research. I argue that even the most progressive current welfare policies lag behind, are ignorant of, or arbitrarily disregard the science on …

How Mean Is The Mean?, Craig P. Speelman, Marek Mcgann

Research outputs 2013

In this paper we voice concerns about the uncritical manner in which the mean is often used as a summary statistic in psychological research. We identify a number of implicit assumptions underlying the use of the mean and argue that the fragility of these assumptions should be more carefully considered. We examine some of the ways in which the potential violation of these assumptions can lead us into significant theoretical and methodological error. Illustrations of alternative models of research already extant within Psychology are used to explore methods of research less mean-dependent and suggest that a critical assessment of the …

Effects Of Hypertension And Diabetes On Sentence Comprehension In Aging, Dalia Cahana-Amitay, Martin Albert, Emmanuel Ojo, Jesse Sayers, Mira Goral, Loraine Obler, Avron Spiro Iii

Publications and Research

Objectives. To assess the impact of hypertension and diabetes mellitus on sentence comprehension in older adults.

Method. Two hundred and ninety-five adults aged 55 to 84 (52% men) participated in this study. Self-report mail survey combined with medical evaluations were used to determine eligibility. Multiple sources were used to determine whether hypertension and diabetes were present or absent and controlled or uncontrolled. Sentence comprehension was evaluated with two tasks: embedded sentences (ES) and sentences with multiple negatives (MN). Outcome measures were percent accuracy and mean reaction time of correct responses on each task.

Results. Regression models adjusted for age, gender, …

On The Future Of Tax Salience Scholarship: Operative Mechanisms And Limiting Factors, David Gamage

Articles by Maurer Faculty

This Essay — written for Florida State University’s symposium on the 100th anniversary of the U.S. federal income tax — evaluates how the literature on tax salience should be advanced in order for it to better guide tax policy over the coming decades. The literature on tax salience analyzes how taxpayers account for the costs imposed by taxation when the taxpayers make decisions or judgments, both in the taxpayers’ roles as voters and as market participants. This Essay evaluates both possible operative mechanisms that might underlie observed tax salience effects and limiting factors that might prevent tax salience effects from …