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Social and Behavioral Sciences Commons

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Selected Works

None

2012

J. A. Aquilina

Human

Articles 1 - 2 of 2

Full-Text Articles in Social and Behavioral Sciences

Truncation, Cross-Linking And Interaction Of Crystallins And Intermediate Filament Proteins In The Aging Human Lens, Roger Truscott, Jason Mcarthur, Andrew Aquilina, Shi-Ping (Jim) Su Oct 2012

Truncation, Cross-Linking And Interaction Of Crystallins And Intermediate Filament Proteins In The Aging Human Lens, Roger Truscott, Jason Mcarthur, Andrew Aquilina, Shi-Ping (Jim) Su

J. A. Aquilina

The optical properties of the lens are dependent upon the integrity of proteins within the fiber cells. During aging, crystallins, the major intra-cellular structural proteins of the lens, aggregate and become water-insoluble. Modifications to crystallins and the lens intermediate filaments have been implicated in this phenomenon. In this study, we examined changes to, and interactions between, human lens crystallins and intermediate filament proteins in lenses from a variety of age groups (0-86 years). Among the lens-specific intermediate filament proteins, filensin was extensively cleaved in all postnatal lenses, with truncated products of various sizes being found in both the lens cortical …


Protein-Bound Uv Filters In Normal Human Lenses: The Concentration Of Bound Uv Filters Equals That Of Free Uv Filters In The Centre Of Older Lenses, Roger Truscott, Andrew Aquilina, Anastasia Korlimbinis Oct 2012

Protein-Bound Uv Filters In Normal Human Lenses: The Concentration Of Bound Uv Filters Equals That Of Free Uv Filters In The Centre Of Older Lenses, Roger Truscott, Andrew Aquilina, Anastasia Korlimbinis

J. A. Aquilina

No abstract provided.