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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Drinking In The Dark: Voluntary Co-Consumption Of Nicotine And Alcohol For Binge-Like Drinking Behavior In Mice, Katherine Benson
Drinking In The Dark: Voluntary Co-Consumption Of Nicotine And Alcohol For Binge-Like Drinking Behavior In Mice, Katherine Benson
Undergraduate Honors Thesis Collection
Alcohol and nicotine are two of the most commonly abused drugs across the United States. Given the high rates of comorbidity, it remains a pressing public health concern to determine how the two drugs interact within the CNS, and how this impacts addictive behavior. The present study investigated the effect of comorbid abuse of nicotine and alcohol on stress and anxiety-like withdrawal symptoms, as both are associated with increased rates of relapse. A voluntary co-consumption, two-bottle choice paradigm was used with nicotine and alcohol to induce binge-like drinking behavior in mice following the drinking in the dark (DID) model of …
“Wide-Awake Drunk”: Observing The Combined Effects Of Alcohol And Caffeine On Somatic Withdrawal Signs In C57bl/6j Mice, Montana Jenkins
“Wide-Awake Drunk”: Observing The Combined Effects Of Alcohol And Caffeine On Somatic Withdrawal Signs In C57bl/6j Mice, Montana Jenkins
Undergraduate Honors Thesis Collection
Caffeine is one of the most widely used psychoactive stimulants in the world and is often used in combination with other substances. The combination of caffeine and alcohol has been shown to induce a stimulated, rather than sedated state, which may result in increased alcohol-attributable accidents (e.g., drunk driving, unprotected sex, and over intoxication). Preclinical research has found mixed results regarding the co-consumption of caffeine and alcohol – some found that caffeine increases alcohol intake while others the opposite. The current study expanded on previous research by testing the effects of combined caffeine and alcohol exposure in a binge-like, mouse …